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Gabe DuBose

@gabe-dubose.bsky.social
42 followers 46 following 16 posts

Evolutionary biologist, computational/quantitative biologist, and bioinformatician Contractor through the St. George Tanaq Corporation supporting the Centers for Disease Control and Prevention (CDC). gabe-dubose.github.io

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Reposted by Gabe DuBose
EcoEvoRxiv @ecoevorxiv.bsky.social · 15/07/2026
Why trait gradients across environments differ within species and across communities: Insights from a theoretical model doi.org/10.32942/X2D...
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Reposted by Gabe DuBose
EcoEvoRxiv @ecoevorxiv.bsky.social · 27/05/2026
Towards a standard model for teaching the process of biological evolution. DOI: doi.org/10.32942/X2G...
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EcoEvoRxiv @ecoevorxiv.bsky.social · 27/05/2026
Ecological and evolutionary dynamics of chlamydiae endosymbionts in social amoeba host communities. DOI: doi.org/10.32942/X2B...
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Reposted by Gabe DuBose
EcoEvoRxiv @ecoevorxiv.bsky.social · 26/05/2026
"The holobiont is not a useful model for most host-microbiome interactions" doi.org/10.32942/X2W...
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EcoEvoRxiv @ecoevorxiv.bsky.social · 25/05/2026
"The roles of density dependence, developmental asynchrony, and niche traversal costs in shaping the evolution of ontogenetic complexity" doi.org/10.32942/X2N...
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Hakeem Jefferson @hakeemjefferson.bsky.social · 06/05/2026
FWIW, I don’t think the major problem in my field, or related ones, is that people need to move faster & produce more. I read a lot of papers as part of the job, and I’m increasingly convinced we’d benefit from fewer papers and better ones, not more mediocre work produced ever more “efficiently.”
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Genetics Society of America @genetics-gsa.bsky.social · 08/05/2026
Dive deep into this new perspective piece in #GENETICS, emphasizing the limitations of classical genetics in deciphering genotype-phenotype relationships and the need for new experimental paradigms to understand context-dependent genetic effects. 🧬 🔗 buff.ly/VOi9xht
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Genetics Society of America @genetics-gsa.bsky.social · 23/04/2026
New research in #GENETICS from @msrivastava95.bsky.social, Ard Louis, and @n-martin.bsky.social focuses on fitness landscapes built from genotype–phenotype maps with a random phenotype-fitness map and makes analytic predictions about their topographical properties. 🔗 for the paper: buff.ly/VnQ796V
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Reposted by Gabe DuBose
Genome Biology and Evolution @genomebiolevol.bsky.social · 09/04/2026
@haorancai.bsky.social and Des Marais investigated gene expression variability in duplicate genes, suggesting a mechanism facilitating gene expression divergence, functional gains, and duplicate retention following small-scale duplications. 🔗 doi.org/10.1093/gbe/evag077 #genome #evolution
doi.org
Dynamics of Expression Variability Contribute to Retention of Small-Scale vs. Whole-Genome Duplicates
Abstract. Genome analyses reveal that gene duplication in eukaryotes is pervasive, providing a primary source for the emergence of new genes. Nevertheless,
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Reposted by Gabe DuBose
EcoEvoRxiv @ecoevorxiv.bsky.social · 06/04/2026
Endosymbiotic mutualism can constrain host diversity and evolved complexity: doi.org/10.32942/X2H...
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Charikleia Karageorgiou (Clio) @evobioclio.bsky.social · 28/03/2026
The special issue Functional and Adaptive Effects of Genomic Structural Variation is now out in Heredity. Many thanks to all contributors for their submissions, to the editorial team at @heredityjournal.bsky.social and to @ellenleffler.bsky.social, @mydennis.bsky.social & @gokcumenlab.bsky.social!
nature.com
Special Issue: Functional and Adaptive Effects of Genomic Structural Variation
See more information on the new Heredity special issue on functional and adaptive effects of genomic structural variation.
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Reposted by Gabe DuBose
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 01/04/2026
Seasonal fluctuations in fitness result in severe reductions in effective population size www.biorxiv.org/content/10.64898/20…
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Reposted by Gabe DuBose
Royal Society Publishing @royalsocietypublishing.org · 15/03/2026
New #RSOS paper: Inferring the dynamics of selective constraints across complex ontogenies: royalsocietypublishing.org/rsos/article...
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Reposted by Gabe DuBose
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 14/03/2026
Evolution as Active Geometry: The Geometric State Equation of the Tree of Life www.biorxiv.org/content/10.64898/20…
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Gabe DuBose @gabe-dubose.bsky.social · 05/03/2026
Super happy to share that my article on inferring the dynamics of selective constraints across complex ontogenies is now out in Royal Society Open Science. My experience with RSOS was great, and I’m happy to be part of the movement towards open science! royalsocietypublishing.org/rsos/article...
royalsocietypublishing.org
Inferring the dynamics of selective constraints across complex ontogenies | Royal Society Open Science | The Royal Society
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Dave Baltrus 🦦 @surtlab.bsky.social · 14/02/2026
<steps to microphone> <taps microphone> Most microbes do not coevolve with *hosts* even when found associated with hosts
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Gabe DuBose @gabe-dubose.bsky.social · 07/01/2026
Happy to share this work by myself and Charles Wang, an incredible undergraduate student I have had the pleasure of working with over the past year, is now out in G3: Genes|Genomes|Genetics. @genetics-gsa.bsky.social academic.oup.com/g3journal/ar...
academic.oup.com
Pleiotropy and the evolutionary stability of plastic phenotypes: a geometric framework
Abstract. Phenotypic plasticity allows organisms to express different traits in response to different environmental or genetic conditions. Understanding th
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Reposted by Gabe DuBose
bioRxiv Ecology @biorxiv-ecology.bsky.social · 02/01/2026
The interaction of dispersal, species sorting, and priority effects, explains a unimodal response of β-diversity to immigration rates www.biorxiv.org/content/10.64898/20…
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Evolution Letters @evolletters.bsky.social · 29/10/2025
Pleiotropy increases with gene age in six model multicellular eukaryotes doi.org/10.1093/evle... Now in @evolletters.bsky.social by Reese Martin and Ann T Tate
doi.org
Pleiotropy increases with gene age in six model multicellular eukaryotes
Abstract. Fundamental traits of genes, including function, length, and Guanine-Cytosine (GC) content, all vary with gene age. Pleiotropy, where a single ge
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Reposted by Gabe DuBose
Evolution Letters @evolletters.bsky.social · 19/12/2025
Why is phenotypic plasticity so common? Models show that even low migration between locally adapted populations can maintain costly plasticity in constant environments, revealing migration as a key driver of plastic trait evolution. academic.oup.com/evlett/advan...
academic.oup.com
Evolution of phenotypic plasticity owing to migration
Phenotypes can change without alterations in the underlying genotype—a phenomenon known as phenotypic plasticity—the evolution of which is typically trigge
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Reposted by Gabe DuBose
Evolution Letters @evolletters.bsky.social · 18/12/2025
Do extra chromosome sets mask bad mutations? Simulations show tetraploids often carry higher genetic load than diploids, depending on dominance, demography, and drift—with important implications for fitness and conservation. academic.oup.com/evlett/artic...
academic.oup.com
The hidden threat: genetic load dynamics in tetraploids and diploids
Polyploid organisms often display unique evolutionary dynamics compared to diploids. One unresolved question is how polyploidy affects the accumulation of
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Reposted by Gabe DuBose
Evolution Letters @evolletters.bsky.social · 18/12/2025
Can we predict gene expression evolution? In flour beetles, transcriptome-wide selection predicts expression change, with indirect selection acting strongest on pleiotropic, network-central genes—linking co-expression architecture to adaptation. academic.oup.com/evlett/artic... Photo: Udo Schmidt
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Gabe DuBose @gabe-dubose.bsky.social · 15/12/2025
My first manuscript reviewed by @peercommunityin.bsky.social (Evolutionary Biology) is now out in @peercomjournal.bsky.social, and I could not be happier with the processes. I am proud to contribute to what I believe is the future of scientific publishing. peercommunityjournal.org/articles/10....
peercommunityjournal.org
The effects of host phylogenetic coverage and congruence metric on Monte Carlo-based null models of phylosymbiosis
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 25/11/2025
Biophysical constraints on mRNA decay rates shape macroevolutionary divergence in steady-state abundances www.biorxiv.org/content/10.1101/202…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 19/11/2025
Mean fitness is maximized in small populations under stabilizing selection on highly polygenic traits www.biorxiv.org/content/10.1101/202…
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Reposted by Gabe DuBose
Chaitanya Gokhale @gokhalecs.bsky.social · 24/07/2025
Very proud that @gauravathreya.bsky.social's brilliant work based on his Master's thesis is out as his first paper in @asn-amnat.bsky.social. Interested in host-symbiont interdependence, eukaryogenesis, evolutionary transitions in individuality, and some great theory to back it?...check out the🧵👇
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Reposted by Gabe DuBose
Chris Catano @chriscatano.bsky.social · 10/11/2025
New paper showing how immigration alters the ecological processes structuring the assembly and variation in #Monarch caterpillar gut #microbiomes. w/ @jaapderoode.bsky.social, @gabe-dubose.bsky.social, Joselyne Chavez, Lydia Fuller-Hall Ecology Letters onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Experimental Immigration Mediates Ecological Selection and Drift in Monarch Microbiome Assembly
The distribution of biodiversity depends on processes operating across scales, yet multiscale paradigms have struggled to permeate host-microbiome research. By integrating multi-scale ecological theo...
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Reposted by Gabe DuBose
Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 11/10/2025
Phylogeny-aware simulations suggest a low impact of unsampled lineages in the inference of gene flow during eukaryogenesis Excellent paper from @tonigabaldon.bsky.social and @microbiobits.bsky.social and Moisès Bernabeu. academic.oup.com/gbe/advance-...
academic.oup.com
Phylogeny-aware simulations suggest a low impact of unsampled lineages in the inference of gene flow during eukaryogenesis
Abstract. The topologies of gene trees are broadly used to infer horizontal gene transfer events and characterize the potential donor and acceptor partners
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Reposted by Gabe DuBose
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 20/09/2025
Quantitative system drift www.biorxiv.org/content/10.1101/202…
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Jorge Peña 🇵🇸 @jorgeapenas.bsky.social · 12/09/2025
"Biologists often become alienated from mathematics at an early stage in their career under the misconception [...] that biology is not a mathematical science. The claim is also often made that mathematical theory is overly simplistic, ignoring the [...] complex nature of biological systems." 1/
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 30/08/2025
Dynamics of fixation probability in a population with fluctuating size www.biorxiv.org/content/10.1101/202…
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Gabe DuBose @gabe-dubose.bsky.social · 21/08/2025
Super excited to share this work from an awesome collaboration between myself and Charles Wang, an incredibly bright and motivated undergraduate in the lab!
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 19/08/2025
Graph Neural Networks for Likelihood-Free Inference in Diversification Models www.biorxiv.org/content/10.1101/202…
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Evolution Letters @evolletters.bsky.social · 18/08/2025
The evolution of reversible plasticity in stable environments doi.org/10.1093/evle... Now in @evolletters.bsky.social by Nicole Walasek et al.
doi.org
The evolution of reversible plasticity in stable environments
Abstract. Reversible plasticity, i.e., the ability to deconstruct phenotypic specializations based on environmental conditions, is widespread in nature. De
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Reposted by Gabe DuBose
bioRxiv Ecology @biorxiv-ecology.bsky.social · 08/08/2025
Strategic citations for a fairer academic landscape www.biorxiv.org/content/10.1101/202…
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Reposted by Gabe DuBose
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 12/07/2025
Developmental system drift in the patterning of the arthropod tarsus www.biorxiv.org/content/10.1101/202…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 07/07/2025
The evolution of high-order genome architecture revealed from 1,000 species www.biorxiv.org/content/10.1101/202…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 28/05/2025
The impact of background selection in mutation-selection-drift balance models of complex trait evolution www.biorxiv.org/content/10.1101/202…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 27/05/2025
Pleiotropy and facilitation of local adaptation in the silverleaf sunflower Helianthus argophyllus www.biorxiv.org/content/10.1101/202…
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Gabe DuBose @gabe-dubose.bsky.social · 23/05/2025
Super happy to share the pre-print for this project after >5 years in the works!
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 17/05/2025
When should adaptation arise from a polygenic response versus few large effect changes? www.biorxiv.org/content/10.1101/202…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 31/03/2025
Sex decreases the pleiotropic costs of local adaptation www.biorxiv.org/content/10.1101/202…
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Pedro Peres-Neto @comecology.bsky.social · 24/03/2025
Why aren't more researchers publishing in society journals? Two potential reasons: 1) They're often unfamiliar to early-career researchers, and/or 2) they need better promotion, a task for all of us.
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Genome Biology and Evolution @genomebiolevol.bsky.social · 09/03/2025
March issue: Amino acids that are more different do have lower rates of exchange over evolutionary time, and this result is general to different taxonomic groups. doi.org/10.1093/gbe/... #MolecularEvolution #AminoAcids #OpenAccess
doi.org
Amino Acid Properties, Substitution Rates, and the Nearly Neutral Theory
Abstract. Do the properties of amino acids affect their rates of substitution? The neutral theory predicts that greater selective constraint leads to slowe
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Chris Catano @chriscatano.bsky.social · 05/03/2025
Excited to share our new paper in Ecology Letters w @lars-brudvig.bsky.social, the culmination of more than a half decade of great fun and research from a landscape-scale experiment in tallgrass prairies! #CommunityAssembly, #PlantDiversity, #RestorationEcology, #Scale, #Prediction
onlinelibrary.wiley.com
Regional Processes Mediate Ecological Selection and the Distribution of Plant Diversity Across Scales
This experiment quantifies how species pool size and immigration influence plant community assembly in restored grasslands. Our findings reveal that greater immigration (seed arrival) and smaller spe...
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 28/02/2025
Accelerated genome shuffling associated with rapid evolution of sexual conflict in seed beetles www.biorxiv.org/content/10.1101/202…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 05/02/2025
Evolution of developmental bias explains divergent patterns of phenotypic evolution www.biorxiv.org/content/10.1101/202…
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Brian J. Enquist @bjenquist.bsky.social · 07/02/2025
Not sure this needs emphasis, but worried about overfitting in #data-driven models? #Theory-driven predictions based on principles offer transparent rationale. Assumptions, parameters & interconnections are easier to assess and refine - it's more about evaluating assumptions than fitting to data 🧪
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