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Manuela Aguirre-Botero

@maguirreb.bsky.social
143 followers 208 following 5 posts

PhD | Parasitologist 📍in 🇫🇷 | Malaria and Immunity Unit | 🇨🇴

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Manuela Aguirre-Botero @maguirreb.bsky.social · 29/04/2026
I am very glad to share the result of a great collaboration with Yevel Flores-Garcia and Fidel Zavala. Endlessly grateful to Rogerio Amino and everyone involved in the project. link.springer.com/article/10.1...
link.springer.com
Relevance of the antibody Fc fragment and epitope valency in protection against malaria sporozoites - EMBO Reports
Protection against infection by Plasmodium falciparum sporozoites is mediated in part by antibodies that recognize the repeated (NPNA)3 epitopes of the circumsporozoite protein (CSP). To evaluate the ...
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Reposted by Manuela Aguirre-Botero
Felix Streicher @virolicious.bsky.social · 08/10/2025
🥳🎉Our brand-new review on species-specific differences in interferon response effectors and the resulting barriers to interspecies transmission of viruses is out, go read it!🥳🎉
journals.plos.org
Viral interferon antagonism shapes host tropism
Outbreaks of zoonotic viruses in human populations highlight the need to understand the molecular factors that influence viral host tropism and interspecies transmission. A virus’s host range is deter...
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Manuela Aguirre-Botero @maguirreb.bsky.social · 02/09/2025
Curious about how antibodies can target Plasmodium sporozoites? Very happy to see this review out, it means a lot to me to finish my PhD research topic with a nice overview of what is known about how anti-CSP Abs neutralize the parasite in the mammalian host.
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Reposted by Manuela Aguirre-Botero
Trends in Parasitology @cp-trendsparasitol.bsky.social · 31/08/2025
New Review alert! Tissue-dependent protection mechanisms of #antibodies targeting #Plasmodium #sporozoites, authored by @maguirreb.bsky.social & Rogerio Amino. #malaria #circumsporozoiteprotein #CSP @pasteur.fr‬ @upcite.bsky.social authors.elsevier.com/a/1lhKa5Eb1x...
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Reposted by Manuela Aguirre-Botero
Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 20/08/2025
🦟 Today is #worldmosquitoday! It's a good opportunity to show what it takes to rear Anopheles mosquitos for our #malaria research. First, let's look at how many mosquitos are bred in the Levashina Lab each year. Check out the following posts to learn what it takes to keep them happy! (1/4) 👇
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Reposted by Manuela Aguirre-Botero
Marine Biological Laboratory @mblscience.bsky.social · 07/04/2025
🔬 This polarized light microscopy image shows Schistosoma mansoni, a parasite that causes schistosomiasis. #WorldHealthDay 🌍 #MicroscopyMonday 📲 Read more about the MBL's research on S. mansoni: bit.ly/3R90jbQ 📷: MBL Biology of Parasitism students and Michael Shribak
Two worm-like shapes, rainbow-colored, on a black background
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Reposted by Manuela Aguirre-Botero
Manuela Aguirre-Botero @maguirreb.bsky.social · 15/02/2025
Curious about the Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody? doi.org/10.7554/eLif...
doi.org
Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody
A late-neutralizing monoclonal antibody targeting the major surface antigen of plasmodial sporozoites impairs the fitness of intracellular parasites, offering mechanistic insights to guide the develop...
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Manuela Aguirre-Botero @maguirreb.bsky.social · 15/02/2025
Curious about the Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody? doi.org/10.7554/eLif...
doi.org
Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody
A late-neutralizing monoclonal antibody targeting the major surface antigen of plasmodial sporozoites impairs the fitness of intracellular parasites, offering mechanistic insights to guide the develop...
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Reposted by Manuela Aguirre-Botero
Camila Duitama @camiladuitama.bsky.social · 04/02/2025
🧬 Excited to share our latest work, MUSET 🌭, a new tool for creating abundance unitig matrices from sequencing data. It was published yesterday in Oxford Bioinformatics if you want to have a look👀 : academic.oup.com/bioinformati... Let's break it down:
academic.oup.com
MUSET: Set of utilities for constructing abundance unitig matrices from sequencing data
AbstractSummary. MUSET is a novel set of utilities designed to efficiently construct abundance unitig matrices from sequencing data. Unitig matrices extend
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Manuela Aguirre-Botero @maguirreb.bsky.social · 03/12/2024
Still in the process of realizing that I just finished my PhD! As my first post I would like to thank again the most amazing boss: Rogerio Amino. Also an special thanks to all the people who were part of this journey Institut Pasteur Education | Université Paris Cité | #PPUprogram
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