Sign in

lettermann.bsky.social

@lettermann.bsky.social
47 followers 80 following 5 posts
PostsRepliesMedia
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 02/09/2026
Very nice thread on our new paper on competing actin networks now live at PRX Life 😀👍🙏🏻
0142
lettermann.bsky.social @lettermann.bsky.social · 03/04/2026
Excited to be part of this collaboration, thanks to all! Our theory of malaria parasite gliding also helps explain diatom motility. A neat twist: the systems are inverted—malaria uses fixed myosins moving short actin filaments, while diatoms use mobile myosins walking on a long actin bundle.
040
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 02/04/2026
Diatom gliding motility is so amazing 🚀 Happy to be together with @lettermann.bsky.social part of this great collaboration 😀 Check out the website of this open access publication to learn how their movement can be fast and flexible at the same time. And to watch many more beautiful movies 😉
0153
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 19/02/2026
Just back from the annual meeting of the @dfg.de priority program #SPP2332 on "Physics of Parasitism", this time at the Robert Koch Institute at Berlin. So many great talks and discussions! Already looking forward to next year's meeting at Hamburg👍
1115
Reposted by @lettermann.bsky.social
Simone Reber @simonereber.bsky.social · 23/01/2026
Chirality shapes life & infection! 😍 Beautiful work by @freddyfrischknecht.bsky.social & @ulrichschwarz.bsky.social labs! Congrats 🍾🍾🍾 rdcu.be/e0rGu
rdcu.be
Chirality of malaria parasites determines their motion patterns
Nature Physics - Malaria parasites move on helical trajectories when infecting their hosts. Now it is shown that they use right-handed chirality to control their motion patterns, and that this...
0131
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 23/01/2026
(2/2) Many thanks to Georgios Pavlou and Isabelle Tardieux for providing such an insightful perspective on our work: www.nature.com/articles/s41...
nature.com
Chirality helps malaria parasites reach their target - Nature Physics
Malaria parasites rapidly glide through host tissues in right-handed spirals. A tilted architecture and asymmetric forces power this chiral motion and help them to transition between different environ...
032
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 23/01/2026
(1/2) Our work with @freddyfrischknecht.bsky.social on the chirality of malaria parasites has found its home in the January issue of @natphys.nature.com: www.nature.com/articles/s41... Moreover, we are very happy that it comes with a news and views article 👍❤️😀
nature.com
Chirality of malaria parasites determines their motion patterns - Nature Physics
Malaria parasites move on helical trajectories when infecting their hosts. Now it is shown that they use right-handed chirality to control their motion patterns, and that this chirality is linked to t...
1179
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 14/01/2026
Now out in @biophysj.bsky.social: our work on the rosettes that sometimes are formed by red blood cells infected by malaria parasites (iRBCs). Surprisingly, they do not marginate, as do white blood cells or "normal" iRBCs, and we explain why (because they are dynamic and effectively soft).
3206
Reposted by @lettermann.bsky.social
Freddy Frischknecht @freddyfrischknecht.bsky.social · 04/12/2025
Join us (again) for another fantastic BioMalPar meeting @embl.org and also a great pre-meeting @ciid-heidelberg.bsky.social
0104
lettermann.bsky.social @lettermann.bsky.social · 27/11/2025
Two videos on how malaria parasites move: helical motion can be "straighter than a straight line" in active particle models @physrevlett.bsky.social, and sporozoite generate chirality differently from Toxoplasma/ookinetes @natphys.nature.com. DOIs: doi.org/10.1103/4kxb... doi.org/10.1038/s415...
140
Reposted by @lettermann.bsky.social
Benjamin Friedrich @friedrich-group.bsky.social · 26/11/2025
Axolotl can regrow lost limbs, matching their body size. How? Our new theory-experiment paper in @pnas.org proposes how oppositely oriented morphogen gradients scaling with animal size promote proportional growth. Great collaboration with @tatianasg.bsky.social @cmcb-tud.bsky.social
Schematic of limb regeneration in axolotl, with growth controlled by two oppositely oriented morphogen gradients (SHH, FGF8).
1349
lettermann.bsky.social @lettermann.bsky.social · 25/11/2025
Super happy to see this major part of my PhD work out in @natphys.nature.com! Three years of fantastic teamwork with Mirko Singer and @freddyfrischknecht.bsky.social and many others. Paper: doi.org/10.1038/s415... More on helical trajectories in @physrevlett.bsky.social: doi.org/10.1103/4kxb...
060
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 01/09/2025
Great session with flash talks at #25EngLife. Here @lettermann.bsky.social presenting his work on malaria parasite motility.
0102
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 26/08/2025
📣 Now out in @physreve.bsky.social‬ as editors' suggestion: our theory on the role of different myosin II isoforms during cell migration. For standard parameters, A and B segregate to the front and the back, respectively. Yet for other parameter values, also oscillations are possible.
1156
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 10/08/2025
Now out in ACS Infectious Diseases @pubs.acs.org: joint work from the Lanzer, Tanaka, Schwarz and Cavalcanti-Adam labs within #SFB1129 on the adhesion footprint of malaria-infected infected red blood cells. Read the open access paper here: pubs.acs.org/doi/10.1021/...
pubs.acs.org
Contact Dynamics of Cytoadhering Plasmodium falciparum-Infected Erythrocytes in Flow
The virulence of the human malaria parasite Plasmodium falciparum is linked to the altered mechanical and adhesive properties of infected erythrocytes, which adhere to the microvascular endothelium to...
0113
Reposted by @lettermann.bsky.social
Freddy Frischknecht @freddyfrischknecht.bsky.social · 14/06/2025
Finally published: discovery of an unusual Arp2/3 complex with surprising new function in transmission of #malaria #parasites. Great work by Franzi Hentzschel, Yvonne Sokolowski + David Jewanski + fantastic collaboration with Matthias Marti: www.nature.com/articles/s41...
34312
Reposted by @lettermann.bsky.social
Ricard Alert Zenón @ricardalert.bsky.social · 10/06/2025
👉 New paper @physrevlett.bsky.social! Active nematics flow spontaneously, driven by their own constituents, e.g. molecular motors or cells. The transition to spontaneous flows was thought to be always continuous. We now discovered that it can also be discontinuous! journals.aps.org/prl/abstract...
journals.aps.org
Nonlinear Spontaneous Flow Instability in Active Nematics
Active nematics exhibit spontaneous flows through a well-known linear instability of the uniformly aligned quiescent state. Here, we show that even a linearly stable uniform state can experience a non...
1103
Reposted by @lettermann.bsky.social
Fever: Global Histories of (a) Disease @feverprojecthd.bsky.social · 29/04/2025
It was a real pleasure to explore the past and present of fever(s) together with my colleague Ulrich Schwarz from Biophysics yesterday! Thanks to the organisers from InterdisciPlenary Heidelberg for making this event happen!
0104
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 10/04/2025
📢 Preprint alert 📢 (1/6) Our work on 3D force inference for intestinal organoids is now on bioRxiv: www.biorxiv.org/content/10.1... Stunning collaboration between @omdrozdowski.bsky.social and @kimboonekamp.bsky.social from the lab of @michaelboutros.bsky.social and with Ulrike Engel. A short🧵...
24611
Reposted by @lettermann.bsky.social
Pintu Patra @pintupatra.bsky.social · 04/04/2025
Check our new paper: "Pair cross-correlation analysis for assessing protein co-localization." Here we provide a quantitative understanding of the image pair cross-correlation method used to analyze spatial co-localization from super-resolution images. t.co/oXBkoo4YI3
t.co
https://www.cell.com/biophysj/fulltext/S0006-3495%2825%2900138-9
131
Reposted by @lettermann.bsky.social
Ulrich Schwarz @ulrichschwarz.bsky.social · 04/04/2025
New paper in @biophysj.bsky.social led by @pintupatra.bsky.social on the analysis of two-color superresolution microscopy data, with an application to malaria-infected red blood cells. Collaboration with Lanzer lab in #SFB1129
042
Reposted by @lettermann.bsky.social
Freddy Frischknecht @freddyfrischknecht.bsky.social · 25/03/2025
Finally: Plasmodium actin filaments visualized in all their glory. Congrats Josie and Vojtech: www.embopress.org/doi/full/10....
embopress.org
Molecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum | EMBO reports
imageimageThis study directly visualises actin cytoskeleton in Plasmodium falciparum sporozoites under native conditions and investigates its structural transitions during locomotion. P. falciparum a...
0133
Reposted by @lettermann.bsky.social
Edouard Hannezo @ehannezo.bsky.social · 17/12/2024
Happy to share the latest work from Preeti Sahu, with Adriana Sanchez-Danes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! See 🧵 below (1/n) bit.ly/3ZXxJzk
15115
lettermann.bsky.social @lettermann.bsky.social · 17/12/2024
Made with #blender, very handy for shiny visualization of more complex (e.g. 3D) data, here the trajectories of malaria sporozoites moving through a hydrogel! Great experiments by Mirko Singer at @freddyfrischknecht.bsky.social lab, we tracked the sporozoites and rendered the resulting trajectories!
020
Reposted by @lettermann.bsky.social
Jose Jimenez-Luna @jjimenezluna.bsky.social · 06/12/2024
Excited to present what we've been up to the last couple years. Introducing BioEmu, a Biomolecular Emulator of protein dynamics: www.biorxiv.org/content/10.1...
biorxiv.org
Scalable emulation of protein equilibrium ensembles with generative deep learning
Following the sequence and structure revolutions, predicting the dynamical mechanisms of proteins that implement biological function remains an outstanding scientific challenge. Several experimental t...
26515