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FrankeLab

@frankelab.bsky.social
239 followers 132 following 13 posts

Plant Natural Products Group at Leibniz University Hannover. We study the biosynthetic pathways of complex specialised metabolites from plants. www.botanik.uni-hannover.de/en/rese…

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Reposted by FrankeLab
Claudia Vickers @claudiavickers.bsky.social · 06/10/2026
📣 HAVE YOUR SAY Synthetic Biology Australasia wants to know how the Industry Rep role can help strengthen connections between the synbio community and industry. Please complete the survey! Link below or scan the QR code, and please re-post forms.cloud.microsoft/pages/respon... @coesb.com.au
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FrankeLab @frankelab.bsky.social · 03/07/2026
It is a great honour to receive this award from one of my favourite journals, Natural Product Reports @natprodreports.rsc.org. Even better to receive it at one of my favourite conference series. Directing Biosynthesis VIII #DBVIII was a fantastic meeting with an outstanding lineup. 👏
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Reposted by FrankeLab
German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 26/05/2026
Hurry up, if you want to present your latest #plantsci research results to an international plant science audience at #BT2026 🚨Abstract submission ends on 31st May 2026 🚨 Please remind to register first to be able to submit your abstract 📆 6-10 September 2026 📍Bochum, Germany botanik-tagung.de
"From industrial Past to Green Future" written around an ancient industry tower typical for the region together with a plant changing colours from blue to green is the motto of the German Society for Plant Sciences international Conference, the Botanik-Tagung, 2026 in Bochum Germany, that brings together plant scientists from several scientific disciplines. The logo highlights the structural change of the Ruhr area, from coal mining + heavy industries to the increasingly important issues of climate protection, sustainability + preservation of biodiversity, with plant sciences at the forefront of this transformation.
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Reposted by FrankeLab
Kai Blin @kblin.bsky.social · 25/05/2026
HMMER is an integral part of the software my whole career is built on. Software that researchers at the DOE have run millions of times. Complete, utter bollocks.
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FrankeLab @frankelab.bsky.social · 19/05/2026
Congratulations, great work! 🎉
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Reposted by FrankeLab
Boas Pucker @bpucker.bsky.social · 07/04/2026
Would you like to confirm your cloning success with full plasmid sequencing? NanoPlasmiQC allows automatic analysis of dozens of plasmids in a single ONT sequencing run: doi.org/10.64898/202... #Genomics #Bioinformatics #OpenScience @puckerlab.bsky.social @unibonn.bsky.social
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Reposted by FrankeLab
Jens Boch @mikrobenjaeger.bsky.social · 25/03/2026
The Leibniz University Hannover/Germany has an open position for a Professor for Molecular Phytopathology (W2TTW3)! Apply before April 27. Please forward this! Contact me for questions. See you in Hannover! 😃🎓🪴🌾🌱🌽🥬🦠🧪🧫🧬🔬🧑‍🔬👩‍🔬👍 www.uni-hannover.de/en/jobs/8410/ (EN) www.uni-hannover.de/de/jobs/8410/ (DE)
uni-hannover.de
University Professorship in Molecular Phytopathology – Leibniz University Hannover
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Reposted by FrankeLab
German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 03/03/2026
#PlantSciJobs #PlantSciJob PhD position: Plant Biochemistry @frankelab.bsky.social @unihannover.bsky.social Start: 1 July 2026 Deadline: 29 March 2026 www.deutsche-botanische-gesellschaft.de/stellenangeb...
deutsche-botanische-gesellschaft.de
Stellenausschreibungen in Pflanzenwissenschaften und Botanik
Stellenausschreibungen in Pflanzenwissenschaften und Botanik
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Reposted by FrankeLab
beckybart.bsky.social @beckybart.bsky.social · 17/02/2026
The Bart Lab at UC Berkeley is looking for a postdoc. Please share!
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FrankeLab @frankelab.bsky.social · 06/02/2026
Congratulations to this great work!
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FrankeLab @frankelab.bsky.social · 16/01/2026
Congratulations, great work! 👏
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Reposted by FrankeLab
Nick Desnoyer @nickdesnoyer.bsky.social · 01/12/2025
The hidden danger of Biorender (& the death of scientific illustration) A short thread 🧵
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FrankeLab @frankelab.bsky.social · 08/10/2025
Congratz! 🎉
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Reposted by FrankeLab
Lichman Lab @lichmanlab.bsky.social · 22/09/2025
Hello! We are currently hiring for two post-doc positions on projects related to plant natural products, enzymes, and developing new systems to make useful small molecules. More details on our website: lichmanlab.weebly.com/post-docs.html
lichmanlab.weebly.com
Post-Docs
We are currently recruiting for two post-doc positions in the Lichman lab that require similar skills and experience. We aim to do a joint recruitment process with a single interview. If you apply...
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Reposted by FrankeLab
German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 16/09/2025
#PlantSciJobs #PlantSciJob Wissenschaftliche Mitarbeit: chemische und molekulare Ökologie trophischer Pflanzen-Insekten-Interaktionen. @unihohenheim.bsky.social in Stuttgart, Germany Start: 1 März 2026 Deadline: 19 Oktober 2025 www.deutsche-botanische-gesellschaft.de/stellenangeb...
deutsche-botanische-gesellschaft.de
Stellenangebote
Stellenausschreibungen in der Botanik und den Pflanzenwissenschaften
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Reposted by FrankeLab
Nadine Ziemert @nadineziemert.bsky.social · 08/09/2025
⏰ Just 7 days left for our Glycopeptide Renaming Challenge! 💡 Share your best name idea and win 500€ 👉 More info and submission here: docs.google.com/forms/d/1ym9... #secmet #NaturalProducts #Antibiotics #NamingChallenge #Glycopeptides @gdwantibiotics.bsky.social @marghesosio.bsky.social
docs.google.com
Naming Challenge: Help Redefine the Glycopeptide Family!
We are excited to launch a naming competition inspired by the recent preprint "Phylogenetic distance and structural diversity directing a reclassification of glycopeptide antibiotics" (https://www.bio...
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FrankeLab @frankelab.bsky.social · 20/07/2025
Ein wirklich toller Artikel, absolut lesenswert! 👍
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Reposted by FrankeLab
Leibniz Universität Hannover (LUH) @unihannover.bsky.social · 14/07/2025
Nachschattengewächse als Basis für Arzneimittel: Forschungsteams der #LUH und der @unibonn.bsky.social‬ entschlüsseln Gensequenz zur Bildung von Steroiden. @dfg.de‬ fördert das Projekt mit rund 511.00 Euro. go.lu-h.de/aNhrb
Nancy Choudhary, Institut für Zelluläre und Molekulare Botanik an der Universität Bonn, bei der Durchführung der Genomsequenzierung der Pflanze Withania somnifera. (Bildquelle: Julie Anne V.S. de Oliveira)
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FrankeLab @frankelab.bsky.social · 10/07/2025
And make sure to also check out the excellent work on the withanolide biosynthetic gene cluster by Claude Becker's group www.pnas.org/doi/10.1073/... and by Jing-Ke Weng's group: www.biorxiv.org/content/10.1...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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FrankeLab @frankelab.bsky.social · 10/07/2025
Big thanks also to anonymous Reviewer 1. Their supportive and constructive report led us to discover the role of the dehydrogenase SDR in the biosynthetic pathway. This is how peer review should work. 👏
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FrankeLab @frankelab.bsky.social · 10/07/2025
Extremely happy to see our withanolide biosynthesis paper out in @natcomms.nature.com‬ rdcu.be/evHOF Fantastic team effort with the Pucker group @bpucker.bsky.social‬ @puckerlab.bsky.social‬ at @unibonn.bsky.social and Heretsch, Herde and Witte groups at @unihannover.bsky.social. Funded by @dfg.de
rdcu.be
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
Nature Communications - Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown....
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Reposted by FrankeLab
Boas Pucker @bpucker.bsky.social · 07/07/2025
There is still time to apply 👇 #MSCA #Postdoc #Biotech #Bioinformatics #Genomics
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Reposted by FrankeLab
Plantae.org @plantaeofficial.bsky.social · 02/07/2025
Plant Science Research Weekly -- Elucidation and recreation of the biosynthetic pathway for taxol (Nature) @cmcclune.bsky.social‬ (Summary by Mary Williams @PlantTeaching.bsky.social) buff.ly/miccEK3 #PlantaePSRW
buff.ly
Elucidation and recreation of the biosynthetic pathway for taxol | Plantae
Paclitaxel (sold as Taxol) is taxane diterpene natural product of yew trees (Taxus spp.) and a potent stabilizer of microtubules that is effective in treatment of cancers. However…
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Reposted by FrankeLab
Jens Boch @mikrobenjaeger.bsky.social · 17/06/2025
PhD position open! 🌾🧫🧬✂️😃 Are you interested in plant pathology and genome editing? Have you ever seen how cool Xanthomonas manipulates the plant cell using TALEs? Don't hesitate to apply! www.uni-hannover.de/en/jobs/id/7...
A cartoon showing a bacterial Xanthomonas cell injecting TALEs into a plant cell to induce expression of target genes.
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Reposted by FrankeLab
Robert Hoffie @forscherrobert.bsky.social · 17/06/2025
Dear #molbio buble, can you suggest any (free) software for cloning and sequence analysis? Something similiar to SnapGene (but cheaper) or Benchling (but locally hosted)? Asking for a newly set up group.
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FrankeLab @frankelab.bsky.social · 11/06/2025
Also check out my News & Views article for more details on the significance of this work 👇 rdcu.be/eqwOy
rdcu.be
Biochemical breakthrough paves way to reliable supply of anticancer drug | Nature
‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees. ‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees.
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FrankeLab @frankelab.bsky.social · 11/06/2025
Fantastic work by the Sattely group on taxol biosynthesis, featuring a highly innovative application of single nuclei sequencing to find elusive biosynthetic genes 👏 www.nature.com/articles/s41...
nature.com
Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature
An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose curren...
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Reposted by FrankeLab
geufloreslab.bsky.social @geufloreslab.bsky.social · 16/04/2025
We're hiring! 🥼 2-year lab technician at UCPH from 01 Aug 🌿 Support our research in plant natural products with relevance in agriculture, nutrition, and medicine. 🧬 Your skills: plant molecular biology and/or tissue culture & transformation 📅 Deadline 18 May 2025 jobportal.ku.dk/administrati...
jobportal.ku.dk
Laboratory Technician, Department of Plant and Environmental Sciences
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FrankeLab @frankelab.bsky.social · 18/03/2025
Started as a very successful master thesis, now published in JACS. Screening sequence similarity networks turned out to be a great way to discover oxidosqualene cyclases with unusual activity from more than thousand plant transcriptome sequence datasets. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants
Triterpenoids and steroids are structurally complex polycyclic natural products with potent biological functions, for example, as hormones. In all eukaryotes, the carbon skeletons of these compounds a...
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Reposted by FrankeLab
Boas Pucker @bpucker.bsky.social · 28/02/2025
I am trying to find everyone working on plant genomics: go.bsky.app/NqARJ7V Please let me know who is already on @bsky.app, but missing in this #PlantGenomics starter pack
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Reposted by FrankeLab
Savage Lab @savagecatsonly.bsky.social · 24/01/2025
What limits rubisco function? Is it the chemical mechanism? Evolution? In this paper, @prywes.bsky.social et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7) doi.org/10.1038/s415...
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Reposted by FrankeLab
Ryo Yokoyama @yokoyama-ryo.bsky.social · 20/12/2024
A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids | Science www.science.org/doi/10.1126/... @science.org
science.org
A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids
Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heter...
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Reposted by FrankeLab
Justin Brower @naturespoisons.bsky.social · 17/12/2024
Anyone up for some #ToxTuesday? A lot of us love spicy foods, and the capsaicin in chili peppers that gives us that heat can be addictive. But is there anything hotter? I'm glad you asked. Yes, yes there is. And it's called RESINIFERATOXIN
The chemical structure of resiniferatoxin, drawn with TWSBI ECO fountain pens in a dark purple and dark gray inks.
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FrankeLab @frankelab.bsky.social · 13/12/2024
Awesome job, Omar, congratulations! 👏
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Andy Truman @andytruman4.bsky.social · 19/11/2024
We have a fully funded 4-year PhD studenship available that builds on parts of this pre-print: biodtp.norwichresearchpark.ac.uk/projects/dis... 🗓️ Deadline 25 Nov 2024 Please do get in touch if you're interested!
biodtp.norwichresearchpark.ac.uk
Discovery and Function of Natural Metalloprotease Inhibitors | Doctoral Training Partnership
TRUMAN_J25DTP2
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