Karl Deisseroth, Peter Hegemann and George Nagel receive the prize for their work on light-gated ion channels and optogenetics

'It's not fraudulent, and it's not really slop,' one expert says

An updated phylogeny of bats is presented, based on new genome assemblies and many ancient fossils and including all known bat families.

2 June 2026 marked the centenary of the death of Sir William Boog Leishman, the Scottish physician after whom Leishmania was named. However, he was not the first to describe the parasite. In this article, we recount this discovery and explain the etymological conventions that ensured Leishman’s name was preserved in scientific history.

A free, searchable database of knockout-controlled antibody characterisation data covering 155 genes and 1620 antibodies. Includes a free e-learning Academy.

wwPDB: Worldwide Protein Data Bank

The Chemical Biology Services Team at the European Bioinformatics Institute (EMBL-EBI) is looking for a talented scientist with a flair for data curation to be responsible for the quality of chemical ...

Bacterial diadenylate cyclase (DAC) enzymes synthesize the nucleotide signal 3′3′ cyclic di-AMP (3′3′-c-di-AMP) to control osmoregulation, cell-wall homeostasis, and DNA-damage responses. Here we disc...

Efficient navigation requires prioritizing information from behaviorally relevant locations. In rats, such selective sampling may arise from theta-paced sweeps in grid and place cell populations, whic...

Now there are lots of AI tools for drug discovery. I think it's difficult to expect 8 years before when I moved to cheminformatics team from MedChem 🙂 And one of the hot area is Folding AI such as Boltz, Alpha fold and OpenFold etc. Boltz-2 has not only cofolding prediction module but also binding affinity prediction module. It will be useful if the module works well.

Read on for early results and what we’ll be looking at in the next phase.

Bringing structural biology to AI: exploring the PDBe MCP servers -

This story is wild. The short version: OpenAI were running a cybersecurity test against an unreleased model, with the model’s guardrail features turned off. Rather than solve the test, the …

Nibrozetone (RRx-001), identified via a phenotypic screen of compounds from the rocket fuel industry, has been advanced by EpicentRx into multiple clinical trials. The molecule additionally received a...

Warning Material for MkDocs is approaching end of life Material for MkDocs is scheduled to reach end of life on November 5, 2026. Until then, maintenance is limited to critical bug fixes and securi...

He won the Nobel Prize for his work on immunology and then went on to define the field of learning and memory.

How useful are Cavity Prediction Algorithms, NMR-AI, (Failing at) Predicting Alternative Binding Modes via Docking and a long list of papers...and maybe the last one of these from PT.

Today's guest blogger questions the operating model around scholarly research and asks why these capabilities are so difficult to sustain at scale.

Defense-associated reverse transcriptases (DRTs) employ DNA synthesis to protect bacteria against phage infection[1][1],[2][2]. We previously showed that DRT10, a tripartite system comprising an RT, a...

FlashPPI2 drives up PPI prediction performance (AUPRC) by 17% while maintaining inference speed at minutes per genome — now deployed across SeqHub's database of over 130,000 microbial genomes.

A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.

How Pandas chunking, Dask, and Polars help process millions of records when adding more compute isn't an option.

Chagas disease is a global public health issue, life-threatening parasitic disease, affecting mostly underserved communities in Latin America. Yet, 10% of infected individuals are diagnosed, and 1% receive etiological treatment. Priority actions for disease elimination by 2030 are streamlining diagnostic methods and evaluating and developing point-of-care diagnostics. We convened 44 researchers, test developers, and health authorities, to provide scientific advice and reach consensus on (i) a harmonized protocol for evaluation of rapid diagnostic tests; (ii) preferred molecular diagnostics characteristics (scope, performance, operational features, pricing, and evaluation standards); and (iii) economic impact evidence needed to have a transformational impact in primary healthcare. We considered global and national perspectives with discordant evidence from multiple disciplines. Our outcomes provide a reference on practical applications and recommendations to promote test development and evaluation. Finally, we debate about the appropriate approach moving forward to meet the diagnostic gap, and propose how investments could be stimulated.

Scientists have long worried about the reliability of commercial antibodies, and the latest findings have sparked fresh concerns.