Reposted by Federica AnastasiBarcelonaβeta Brain Research Center @barcelonabeta.bsky.social · 10/03/2026🗓️ Tuesday, March 17 🗣️ Maria Pujol-Torrens 📌 Auditorium 10+11 | 14:00 – 15:30 “Dissociable network-based mechanisms underlie cognitive resilience in aging and preclinical Alzheimer's disease” 131
Reposted by Federica AnastasiBarcelonaβeta Brain Research Center @barcelonabeta.bsky.social · 10/03/2026Poster session on Tuesday 17: "Biomarkers of neurodegeneration predict cognitive decline in preclinical #Alzheimer's Disease" 👤 Anna Coward 131
Reposted by Federica AnastasiBarcelonaβeta Brain Research Center @barcelonabeta.bsky.social · 10/03/2026🗓️ Friday, March 20 🗣️ Clara Gallay (@clara-gallay.bsky.social) 📌 Auditorium 15 | 13:50 – 15:50 “Parity interacts with amyloid status to influence hippocampal volume and cognition in postmenopausal women at risk of Alzheimer’s disease” 142
Reposted by Federica AnastasiBarcelonaβeta Brain Research Center @barcelonabeta.bsky.social · 10/03/2026🗓️ Tuesday, March 17 🗣️ Dr. Marta del Campo 📌 Room Hall 180-181| 11:00 – 13:00 Chairing the session and presenting “Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias” 121
Reposted by Federica AnastasiDementia Researcher @dementiaresearcher.bsky.social · 06/08/2025Roche is seeking a Lead Clinical Director, Neurology. To Lead late-stage trials for Trontinemab in Alzheimer’s, shape strategy, and make real-world impact in a supportive, inclusive culture. Closing date: 3rd October www.dementiaresearcher.nihr.ac.uk/job/clinical...dementiaresearcher.nihr.ac.ukClinical Director: Alzheimer’s disease - DEMENTIA RESEARCHERClinical Director, Neurology – Roche. Lead late-stage trials for Trontinemab in Alzheimer’s, shape strategy, and make real-world impact. 022
Reposted by Federica AnastasiVanessa Linke @massspecvanili.bsky.social · 31/07/2025🤩 JOB ALERT 🤩 Come work with me and two cutting-edge LC-MS/MS systems at our brand new Mass Spectrometry Facility @iimcb.bsky.social in Warsaw! Apply here tinyurl.com/y47mzafa or send any questions my way. #TeamMassSpec please share widely!tinyurl.comMass Spectrometry Technology Specialist, Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie, WarszawaJob offer Mass Spectrometry Technology Specialist, Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie, Warszawa 1159
Reposted by Federica AnastasiPastelBio @pastelbio.bsky.social · 31/07/2025Perspectives in Computational Mass Spectrometry: Recent Developments and Key Challenges chemrxiv.org/engage/... --- #proteomics #prot-preprint 052
Reposted by Federica Anastasifhernandezv.bsky.social @fhernandezv.bsky.social · 29/07/2025#AAIC2025 Today, Tuesday, July 29th, I am presenting my poster “Sex-specific associations between age-related blood proteins, cognition and Alzheimer’s biomarkers” (N. 364) Thanks to my supervisors and collaborators who made this work possible. @marcsuarezcalvet.bsky.social @fanastasi.bsky.social 051
Reposted by Federica AnastasiBarcelonaβeta Brain Research Center @barcelonabeta.bsky.social · 27/07/2025📍Day 1 at #AAIC25 kicks off with strong participation from the #BBRC! Have a look at today’s schedule!! ⤵️ We'll keep you posted! @alzassociation.bsky.social 141
Reposted by Federica AnastasiBarcelonaβeta Brain Research Center @barcelonabeta.bsky.social · 16/07/2025Early detection and effective treatment of neurodegenerative diseases remains one of the great scientific and medical challenges of the 21st century. Read our latest piece of news: www.barcelonabeta.org/en/news/news... @marcsuarezcalvet.bsky.social @natvilortejedor.bsky.social @fanastasi.bsky.social 131
Reposted by Federica AnastasiPastelBio @pastelbio.bsky.social · 04/07/2025Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome www.nature.com/artic... --- #proteomics #prot-paper 031
Federica Anastasi @fanastasi.bsky.social · 02/07/2025I'm extremely happy to share that I've been awarded the @brightfocus.bsky.social Postdoctoral Grant! 🎉🙌 Huge thanks to BFF for their trust, and heartfelt gratitude to my mentors @marcsuarezcalvet.bsky.social and @bettytijms.bsky.social for their trust and help every step of the way! 💪✨ 162
Reposted by Federica AnastasiBarcelonaβeta Brain Research Center @barcelonabeta.bsky.social · 02/07/2025🎉 Great news!! Dr. @fanastasi.bsky.social has been awarded a prestigious research grant from the @brightfocus.bsky.social to advance personalized approaches to #Alzheimer’s disease. Her project is one of 50 selected globally this year⤵️ www.barcelonabeta.org/en/news/news... 143
Reposted by Federica AnastasiMireya Plass @mireyaplass.bsky.social · 04/12/2024Please RT: In my lab we are looking for computational #postdoc researchers to apply to a #juandelacierva or #embo postdoctoral fellowships to work on projects on post-transcriptional regulation on single-cell data (method development and/or data analysis). Contact me if you are interested! 11021
Reposted by Federica AnastasiUS HUPO @us-hupo.org · 13/05/2025Are You Hiring? Let the US HUPO community know you're looking for a talented proteomic scientist! Post your job here: us-hupo.org/US-HUPO-... Looking for a job? Check out the job board! #ProteomicsJobs 021
Reposted by Federica AnastasiProteomicsNews (Ben Orsburn) @proteomicsnews.bsky.social · 12/04/2025A human protein tissue specifity atlas attempt that is actually good! proteomicsnews.blogspot.com/2025/04/a-ti... - punchline might be that there aren't all that many linear protein sequences that are tissue specific. Proteoforms are probably the only correct answer.proteomicsnews.blogspot.comA tissue proteome specificity map that is actually good!I am so excited by this great new resource! And not just because the most recent big paper purporting to do such a thing ( this one - s... 1132
Reposted by Federica Anastasibiofinder.bsky.social @biofinder.bsky.social · 09/04/2025New manuscript alert! Can blood-based biomarkers measured on a fully automated platform accurately identify Alzheimer’s disease (AD) pathology?🩸 Our new multi-cohort study has now been published in @naturemedicine.bsky.social: nature.com/articles/s41.... A thread🧵nature.comPlasma phospho-tau217 for Alzheimer’s disease diagnosis in primary and secondary care using a fully automated platform - Nature MedicineAmong 1,767 patients in 5 centers, a fully automated blood test showed high accuracy for Alzheimer’s pathology in secondary and primary care using a predefined cutoff. 143
Federica Anastasi @fanastasi.bsky.social · 03/04/2025Had a great time today at #ADPD2025 presenting our research on global and sex-specific predictors of cognitive changes in preclinical AD. Huge thanks to my amazing colleagues for their incredible support! #proteomics #BarcelonaBeta #ALFAstudy 020
Reposted by Federica AnastasiNat Vilor-Tejedor @natvilortejedor.bsky.social · 02/04/2025Excited to present at the Alzheimer's Insight Summit Industry Symposium at #ADPD2025! Grateful to #ADDI team for the invitation to share how my team leverages the AD Workbench to advance our research. Huge thanks to all partners for the great initiative! #ADresearch 041
Reposted by Federica AnastasiProf Malú Gámez Tansey @malutansey.bsky.social · 02/04/2025Great #ADPD2025 #Forum02 on #integrating #bloodbasedbiomarkers w #CSF #imaging and #digital chaired by @melissamurray and @oskarhansson 0121
Reposted by Federica AnastasiNat Vilor-Tejedor @natvilortejedor.bsky.social · 03/04/2025Fantastic presentation by our amazing team member #PatriciaGenius, brilliantly showcasing epidemiological and genetic risk factors of regional white matter hyperintensities using strong statistical methods for profile selection! #ADPD2025 #NBGteam 🧠🧬 021
Reposted by Federica AnastasiEMBL-EBI Training @training.ebi.embl.org · 27/03/2025If you’re looking to gain hands-on training in the basics of mass spectrometry and proteomics bioinformatics, then this course is for you! Make sure you’ve submitted your application by 6 April: www.ebi.ac.uk/training/eve... Some financial assistance is available - see the course website. 🧪🧶🧬🖥️ 1239
Reposted by Federica AnastasiProteomicsNews (Ben Orsburn) @proteomicsnews.bsky.social · 27/03/202536,000 plasma proteomes by mass spectrometry? No nanoparticles?!?! 2,000 protein depth? Can NOT wait to read this. proteomicsnews.blogspot.com/2025/03/pca-...proteomicsnews.blogspot.comPCA-N -36,000 human plasma proteomics samples by mass spec in 311 days!WHOOOOOOOOOOOOOOOOOOOOOOOOOOOOOAAAAAAAA!!!!! Dataset for reanalysis alert!! Mann lab optimized perchlorate based enrichment to get a supe... 4346
Federica Anastasi @fanastasi.bsky.social · 01/03/2025Unbelievable. This is just insane. What can we do from Europe to support this and other research projects being shut down in the USA? Scientists shouldn't have to fight for keeping knowledge alive but apparently they should start to. 040
Reposted by Federica AnastasiAlexa Pichet Binette @alexapb.bsky.social · 20/02/2025Join us on March 21st for a primer on GWAS in AD and a great discussion with leaders in the field 🧠 🧬 031
Reposted by Federica AnastasiVadim Demichev @vadim-demichev.bsky.social · 29/01/2025DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...github.comRelease DIA-NN 2.0 · vdemichev/DiaNNWe are excited to announce DIA-NN 2.0, the most significant milestone in the history of DIA-NN development. Key Breakthroughs Proteoform Confidence mode: DIA-NN 2.0 solves the long-standing chall... 615039
Reposted by Federica AnastasiJackie Flynn Mogensen @jackiefmogensen.bsky.social · 23/01/2025If you're a researcher impacted by the NIH/CDC/FDA travel and communication pause and are open to chatting about your experience, big or small, please reach out to me at jmogensen@motherjones.com or DM for Signal 5140721218
Reposted by Federica AnastasiNature @nature.com · 24/01/2025In an unprecedented move, research-grant reviews have been suspended indefinitely at the world’s largest public funder of biomedical research go.nature.com/4gc0Bc5go.nature.com‘Never seen anything like this’: Trump’s team halts NIH meetings and travelIn an unprecedented move, research-grant reviews have been suspended indefinitely at the world’s largest public funder of biomedical research. 11221136
Reposted by Federica AnastasiJulia Bubis @jbubis.bsky.social · 16/01/2025Finally, it is out!:) #SCP #Astral #massspectromentry www.nature.com/articles/s41...nature.comChallenging the Astral mass analyzer to quantify up to 5,300 proteins per single cell at unseen accuracy to uncover cellular heterogeneity - Nature MethodsAn ultra-low-input single-cell proteomic workflow is optimized to yield maximum proteome coverage with high accuracy and precision on the Orbitrap Astral mass spectrometer. 1195
Reposted by Federica AnastasiTim Mathews @timmathews.bsky.social · 10/12/2024Here are my book recommendations for the new year: Read the books you already bought. 4746481858
Reposted by Federica AnastasiHeidi Jacobs @heidijacobslab.bsky.social · 28/11/2024New work from our postdoc Elouise Koops just got published: #locuscoeruleus metabolism is elevated in preclinical Alzheimer’s disease, and provides resilience against cognitive decline! In collaboration with Joyita Dutta (UMass) alz-journals.onlinelibrary.wiley.com/doi/10.1002/...alz-journals.onlinelibrary.wiley.comElevated locus coeruleus metabolism provides resilience against cognitive decline in preclinical Alzheimer's diseaseINTRODUCTION Alterations in locus coeruleus’ (LC) metabolic turnover are associated with Alzheimer's disease (AD)-pathology and cognitive impairment. However, the evolution of these changes across d... 14517
Reposted by Federica AnastasiEric Topol @erictopol.bsky.social · 27/11/20242 new studies on brain aging with sex-specific findings —Angiogenesis factors www.science.org/doi/10.1126/... —Loss of gray matter press.psprings.co.uk/jnnp/novembe... 414545
Reposted by Federica AnastasiCarolyn Bertozzi @carolynbertozzi.bskyverified.social · 26/11/2024Exciting new discovery from colleagues @stanfordmedicine.bsky.social, astrocyte metabolism compromised by amyloid and tau oligomers leading to insufficient support for neurons. Possible new target for treating AD. www.science.org/doi/10.1126/...science.orgRestoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologiesImpaired cerebral glucose metabolism is a pathologic feature of Alzheimer’s disease (AD), with recent proteomic studies highlighting disrupted glial metabolism in AD. We report that inhibition of indo... 420947
Reposted by Federica AnastasiMaurizio De Pittà @mdepitta.bsky.social · 24/11/2024I am giving a 2-day #advanced #course on #astrocyte multiscale #models at the University of #Padua IT on April 10--11, 2025 #EMBO. An excellent opportunity to learn how to include #neuron-#glia #interactions in your models, from molecules to networks. Info & Registration: tinyurl.com/yx3m6acy 1155
Reposted by Federica AnastasiOded Rechavi @odedrechavi.bsky.social · 19/11/2024Hope I'm the first to post this all time classic on this platform 392909620
Reposted by Federica AnastasiEric Topol @erictopol.bsky.social · 22/11/2024The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers www.cell.com/cell/fulltex... 418939
Reposted by Federica Anastasigenomicscow.bsky.social @genomicscow.bsky.social · 20/11/2024Somalogic, Olink, and Alamar are casting doubt on each other’s data, proudly calling out lack of correlation. I know why they do this but in the long run as it casts doubt on affinity approaches as a whole. We will think lots of data is generated that is trash and won’t know which 4265
Reposted by Federica AnastasiEduardo Zimmer @erzimmer.bsky.social · 20/11/2024Paper of the year 2 👉 astrocytes, glucose, lactate, IDO1 and impressive results! 👇👇👇👇👇👇👇👇👇👇👇👇👇 www.science.org/doi/10.1126/...science.orgRestoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologiesImpaired cerebral glucose metabolism is a pathologic feature of Alzheimer’s disease (AD), with recent proteomic studies highlighting disrupted glial metabolism in AD. We report that inhibition of indo... 03212
Reposted by Federica AnastasiPastelBio @pastelbio.bsky.social · 17/11/2024Addressing statistical challenges in the analysis of proteomics data with extremely small sample size: a simulation study - BMC Genomics bmcgenomics.biomedce... --- #proteomics #prot-paper 051
Reposted by Federica AnastasiCrystal M. Glover, Ph.D. @cgster.bsky.social · 15/11/2024New press release today featuring our manuscript that sets forth recommendations to make dementia research more inclusive. I am so happy to get this work into the scientific register. I am so proud to serve as senior author. #GSA2024 #geronsky www.alz.org/news/2024/pu...alz.orgCommunity Members and Researchers Publish Recommendations to Make Dementia Studies More InclusiveIn the Alzheimer's Association journal, authors discuss Public and Participant Involvement (PPI) and working with community members in dementia studies. 06827
Reposted by Federica AnastasiAlejandro Brenes @ajbrenes.com · 10/11/2024#teamMassSpec here is a starting pack in case you just moved over, or in case you've been absent for a while. This is #proteomics or #massspec related. The pack is not comprehensive but it's a start. go.bsky.app/HH7kqEh 198751