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Preprint servers and open science platforms have revolutionized the scientific process. A fundamental feature of these platforms is a lack of peer review—virtually anyone with an internet connection can upload their research in a few clicks. Although this setup has facilitated rapid dissemination of results and open access to research, it has also enabled fringe researchers to post and share pseudoscientific, genetically informed studies of differences in behavior that often advance racial hereditarian and eugenic claims. Because preprint archives are now routinely used by mainstream academics, preprints grant a degree of legitimacy to fringe research that otherwise may have been relegated to a blog post or fringe publication. Previous studies have documented individual examples of pseudoscientific, genetic studies of group differences being posted on preprint archives, but the scope of this problem remains unclear, making it difficult to formulate responses and potential solutions. The present study quantified and characterized pseudoscientific studies of group differences in behavior—including studies that used genetic methods—housed on popular preprint servers and open science collaboration platforms. Dozens of such preprints were identified. Preprinted studies on group differences often analyzed controversial phenotypes, most frequently intelligence and related traits, and furthered classical, widely rejected hereditarian and eugenic theories. Genetically informed analyses rested on fundamentally flawed assumptions about heritability and polygenic scores. The Preprint Problem is indicative of a broader effort to weaponize mainstream academic research and its mechanisms, including Open Science, and a recent resurgence of scientific racism and eugenics. Potential responses to these challenges are introduced.

Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.

Over the last years, the decreased costs and enhanced accessibility to large genome-wide association studies datasets have laid the foundations for the development of polygenic risk scores (PRSs). ...

Question Is variation in global functioning among people with schizophrenia associated with genetic differences? Findings In this genetic association study of 5991 adults with schizophrenia and 59,79...