iiinova — where your digital self keeps evolving

Sophie Bell @sophiebell.bsky.social · 13/03/2026

Alzheimer's disease cases are projected to double within the next two decades. Research funding was just cut in half. Needless to say, the math ain't mathing.

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Sophie Bell @sophiebell.bsky.social · 06/02/2026

Packed first day at #INS2026inPhiladelphia! Loved sharing our Lifespan Cognitive Health Risk Score with a room full of neuropsychologists 🧠 @ent3c.bsky.social Then caught Abeera Ahmad presenting our poster on concordance between amyloid positivity + neuropsych testing @ins-slc.bsky.social

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Reposted by Sophie Bell

Advancing Excellence in Scholarship Research Conference @aesconferenceuva.bsky.social · 20/01/2026

We invite you to register and/or submit an abstract to present at UVA's virtual Advancing Excellence in Research Scholarship Research Conference, on April 10th, 2026! The abstract submission deadline will be on February 27, 2026! Registration is free. Submit here: forms.gle/dGqvvBQC29hJ...

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Sophie Bell @sophiebell.bsky.social · 19/01/2026

(1/4) Thrilled to share our new paper out now in @geronsociety.bsky.social Journals of Gerontology. The association between birthweight and cognitive ability declined exponentially across the lifespan. A longitudinal twin study helped us unpack why... academic.oup.com/psychsocgero...

academic.oup.com

Nonlinear decline in the association between birth weight and cognitive ability from infancy to midlife in a community sample of twins

AbstractObjectives. Birth weight is a widely used indicator of prenatal experiences in models of the developmental origins of cognitive ability across the

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Sophie Bell @sophiebell.bsky.social · 10/11/2025

Another intriguing Atlantic read from Eric Turkheimer @ent3c.bsky.social and Paige Harden @kph3k.bsky.social! "We can add three and two to make five, but we cannot add scientific breakthroughs to bigotry and arrive at a tidy, incontrovertible sum. One deed sits stubbornly beside the other."

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Reposted by Sophie Bell

Eric Turkheimer @ent3c.bsky.social · 13/10/2025

In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.

theatlantic.com

Your Genes Are Simply Not Enough to Explain How Smart You Are

Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.

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Sophie Bell @sophiebell.bsky.social · 10/09/2025

Grateful to UVA Today for featuring our recent study! And big thanks to the creative mind behind this mildly creepy yet amazing graphic - who knew DNA methylation aging and twins could come together so seamlessly? news.virginia.edu/content/uva-...

news.virginia.edu

UVA study of identical twins links faster aging to memory decline

Researcher Sophie Bell and professor Eric Turkheimer identified how genetics, environment and biology combine to affect cognitive health.

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Reposted by Sophie Bell

Aging Journal @aging-us.bsky.social · 30/07/2025

📈 #TrendingWithImpact: A new #researchpaper was #published on July 23, titled “Second generation DNA methylation age predicts cognitive change in midlife: the moderating role of childhood socioeconomic status.” 🔗 doi.org/10.18632/agi... #aging #quote #openaccess #publishing #twins #DNAMethylation

Second generation DNA methylation age predicts cognitive change in midlife: the moderating role of childhood socioeconomic status

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Reposted by Sophie Bell

Eric Turkheimer @ent3c.bsky.social · 23/07/2025

New paper with first author @sophiebell.bsky.social. We show that epigenetic clocks predict decline in IQ between adolescence and midlife, between and within twin pairs, and that the effect is stronger among people from low SES backgrounds. A Scarr-Rowe-adjacent effect. www.aging-us.com/advance

Graph illustrating interaction effect whereby epigenetic clocks predict IQ decline more strongly in twins from low SES backgrounds.

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Sophie Bell @sophiebell.bsky.social · 06/07/2025

Another great BGA meeting in Atlanta.. glad to keep the lab tradition going @ent3c.bsky.social!

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Sophie Bell @sophiebell.bsky.social · 30/05/2025

Major congrats to our colleagues at USC!! The 5ADCSI test for Alzheimer's disease blood biomarkers is now validated and published in Journal of Alzheimer's Disease. The 5ADCSI is a low-cost, sensitive assay capturing plasma amyloid-β, pTau, NfL, and GFAP: journals.sagepub.com/doi/10.1177/...

journals.sagepub.com

High precision and cost-effective multiplex quantification of amyloid-β40, amyloid-β42, p181Tau, p217Tau, neurofilament light chain, and glial fibrillary acidic protein from plasma and serum - Farshad...

Background Current methods to quantify blood biomarkers for Alzheimer's disease (AD) are expensive and are not widely available. Objective To develop a lo...

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