Tu et al. present a systematic analysis of the tumor microenvironment across 14,837 breast cancers, identifying distinct cellular patterns that predict disease-specific survival independently of genomic and intrinsic subtypes. Characterizing microenvironment composition may provide critical prognostic markers that can complement current molecular classification for treatment selection and preventing recurrence.

Au cours de la journée internationale de mobilisation « Stand Up for Science », des chercheurs français de toutes les disciplines ont appelé à la solidarité internationale face à la brutalité de l’administration Trump envers certains pans de la recherche.

Le CNRS rappelle son engagement indéfectible pour préserver la liberté académique. L'indépendance des scientifiques et la possibilité de mener une recherche publique fondamentale libre sont des princi...

In solidarity Dear Colleagues in the USA, We wish to express our unwavering support for you during these alarming times. From our positions as researchers and academics in Europe, we are observing …

Scholars warn of president’s lawlessness in actions such as federal funding freeze and birthright citizenship order

Imagining how we'd cover overseas what's happening to the U.S. right now

Researchers from the Tanenbaum group have developed a new microscopy technique to observe how ribosomes function in cells.

Dans le cadre de son programme de recherche intégrée « Cerveau, cancer et immunité – dialogue cellulaire dans les tumeurs cérébrales », […]

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Appointed Executive Director of Paris Brain Institute for a five-year term, Professor Stéphanie Debette took up her new position on January 1, 2025. She succeeds Professor Alexis Brice, who has served...

Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with aberrant development in gliob...

Nature Cell Biology - Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with...

A study using glioblastoma mouse models, serial magnetic resonance imaging and single-cell profiling details changes in the identity and balance of cellular states from initiation of tumorigenesis to ...

Gonzalez-Aponte et al. identify daily glucocorticoid receptor signaling as an intrinsic driver of glioblastoma (GBM) progression and a synchronizer of tumor clock gene expression to the host. This work provides an intrinsic circadian driver, and therapeutic target, to slow GBM growth, and offers considerations for glucocorticoid use in the clinic.