Macroalgae, the dominant primary producers of Earth’s most productive coastal vegetated ecosystems and a vital component driving ocean carbon sequestration, produce ∼5 to 80% of their net primary prod...

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The idea of ‘biological agency’ — that life devises its own goals and behaves accordingly — complicates our understanding of what it means to be alive. But does it serve a scientific purpose?

4 scientists explain why the Reflecting Pool may be green instead of blue on July 4.

Establish David Attenborough Day on 8th May

Clardy, J. & Walsh, C. Lessons from natural molecules. Nature 432, 829–837 (2004). Xu, T. et al. NPBS Atlas: a comprehensive data resource for exploring the biological sources of natural products. J. Cheminform. 17, 172 (2025). Newman, D. J. & Cragg, G. M. Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019. J. Nat. Prod. 83, 770–803 (2020). Koehn, F. E. & Carter, G. T. The evolving role of natural products in drug discovery. Nat. Rev. Drug Discov. 4, 206–220 (2005). Vanni, C. et al. Unifying the known and unknown microbial coding sequence space. eLife 11, e67667 (2022). Wirbel, J., Bhatt, A. S. & Probst, A. J. The journey to understand previously unknown microbial genes. Nature 626, 267–269 (2024). Scherlach, K. & Hertweck, C. Mining and unearthing hidden biosynthetic potential. Nat. Commun. 12, 3864 (2021). Medema, M. H. et al. antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences. Nucleic Acids Res. 39, W339–W346 (2011). Skinnider, M. A. et al. Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM). Nucleic Acids Res. 43, 9645–9662 (2015). Hannigan, G. D. et al. A deep learning...

Biotic interactions modulate protein abundance, reducing functional redundancy and increasing productivity in complex bacterial communities.

This study introduces KIMMDY, a biomolecular reaction emulator that models complex biochemical reactions in dynamic atomistically resolved systems, from protein radical chemistry to DNA photoreactions.

A nature-inspired ion trap enabling massively parallel mass spectrometry.