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Sanjay Popat

@drsanjaypopat.bsky.social
523 followers 191 following 28 posts

Thoracic Oncologist, Royal Marsden Hospital | Professor, Institute of Cancer Research | Past chair, British Thoracic Oncology Group | Views are my own

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Reposted by Sanjay Popat
D. Ross Camidge @drcamidge.bsky.social · 18/05/2026
HOPE summit keynote now on YouTube - enjoy. www.youtube.com/watch?v=UMNY...
youtube.com
HOPE Summit 2026 Keynote -- Hope 2026: Wagons Roll
YouTube video by LUNGevityFoundation
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D. Ross Camidge @drcamidge.bsky.social · 21/01/2026
www.sciencedirect.com/science/arti... Now in press in Journal of Thoracic Oncology - a hypothesis I’ve presented at meetings for a couple of years but never put in writing before.
sciencedirect.com
Hiding in Plain Sight: The Neuro-Protective Benefit of Tyrosine Kinase Inhibition in Non–Neurotrophic Receptor Tyrosine Kinase-Driven Lung Cancers
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Davidmcmahon @drdavidmcmahon.bsky.social · 24/01/2026
Pleased to publish a case report exploring a number of interesting elements of ERBB2 (HER2) mutated NSCLC on @jtoonline.bsky.social with @drsanjaypopat.bsky.social and @dralexiusjohn.bsky.social www.jtocrr.org/article/S266...
jtocrr.org
Acquired ERBB2 amplification and overexpression as on-target resistance mechanisms to zongertinib with subsequent response to trastuzumab deruxtecan; a case report
A number of drugs are in development for the treatment of ERBB2(HER2)-mutated Non-Small Cell Lung Cancer (NSCLC) including antibody-drug conjugates (ADCs) such as trastuzumab deruxtecan (T-DXd) and ty...
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Davidmcmahon @drdavidmcmahon.bsky.social · 30/01/2026
pubmed.ncbi.nlm.nih.gov/41609978/ Delighted to explore the complex landscape of EGFRm NSCLC in 2026 with @drsanjaypopat.bsky.social and @dralexiusjohn.bsky.social Mechanisms of resistance FLAURA vs MARIPOSA vs FLAURA 2 Decision making after these regimens Genomic informed and agnostic approaches
pubmed.ncbi.nlm.nih.gov
Current and Emerging Treatment Landscape of Common EGFR-Mutated Advanced Non-small Cell Lung Cancer - PubMed
Osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has been standard of care as monotherapy for EGFR-mutated advanced non-small cell lung cancer since reporting of the FLAURA phase III clinical trial, which demonstrated superiority over first-generatio …
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Sanjay Popat @drsanjaypopat.bsky.social · 16/12/2025
There’s a lot going on and new in #lungcancer. Be there to understand the latest developments!
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Sanjay Popat @drsanjaypopat.bsky.social · 28/10/2025
Fellows, writing a manuscript with me? The 10 golden rules never grow old
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Sanjay Popat @drsanjaypopat.bsky.social · 05/09/2025
For those of you wondering why newer antibodies are now called -tugs -barts -migs and -ments not -mabs, this is the official @who.int INN explainer tinyurl.com/49bxfn4t
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BTOG @btog.bsky.social · 31/07/2025
🌍 Why do people who’ve never smoked get lung cancer? Our first session dives into epidemiology, environmental aetiology, and early detection. With @ruthstraussfdn.bsky.social‬ 🧠 #BTOG2025 | 📍 London | 📅 13 Nov 🔗 www.btog.org/non-smo... #LungCancer #LCSM #NonSmokingLungCancer
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The OncoAlert Network 🚨 @oncoalert.bsky.social · 26/05/2025
The #ASCO25 #OncoAlertTOP10 Abstracts in #LungCancer 🫁 These are some of our picks of TOP abstracts we look forward to be presented at the upcoming ASCO Meeting in Chicago 🇺🇸 @biagioricciutimd.bsky.social ‬ @stephenvliu.bsky.social @drsanjaypopat.bsky.social Ping @drjnaidoo.bsky.social
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Dr. Herbert Loong @herbloongmd.bsky.social · 26/04/2025
Thank you #LCS2025 in #KualaLumpur 🇲🇾 for hosting an informative & interactive lung cancer meeting! Always pleasure to meet colleagues who are keen to move our 🫁 field forward. #LCSM @apoddc @APCLC_2023 @stephanieplsaw @drdaviddwlee #BeungChulAhn #PJVoon #JenniferLeong @drsanjaypopat.bsky.social
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Tom Newsom-Davis @tnewsomdavis.bsky.social · 10/04/2025
❗️FLAURA2 approved by NICE❗️ Already on BlueTeq! Now an option for 1L EGFR+ pts Worth familiarising yourself with the higher risk subgroups that seemed to better with this regimen
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Sanjay Popat @drsanjaypopat.bsky.social · 10/04/2025
Great to see this important step for our EGFR mutant patients: FLAURA-2 approval by NICE. Interesting to note that the reimbursement (Blueteq form) allows a single cycle of chemo if clinically urgently indicated, but no access if PD on adjuvant osi. @btog.bsky.social @egfrpositiveuk.bsky.social
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Sanjay Popat @drsanjaypopat.bsky.social · 05/04/2025
Very important dataset and a set forward to potential ambulatory delivery in the future.
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Tom Newsom-Davis @tnewsomdavis.bsky.social · 13/03/2025
HER2 mutated NSCLC increasingly important as a rest of new TKI show promising effectiveness in early phase trials Riyaz Shah and I discuss these, and other HER2 targeted treatments
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Sanjay Popat @drsanjaypopat.bsky.social · 09/03/2025
Very nice perspective from Drs Tannock, De Vries & colleagues @pmresearch-uhn.bsky.social in @thelancetoncol.bsky.social on dose optimization for oncology drugs: an area that @nihr.bsky.social should be evaluating, IMHO @nhsengland.bsky.social @bopa.org.uk shorturl.at/aszUO
shorturl.at
Dose optimisation to improve access to effective cancer medicines
Access to many cancer medicines on WHO's Essential Medicines List (EML) is restricted because of price, especially in low-income and middle-income countries (LMICs). Other cancer medicines that have b...
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Chloe Waterson @chloewaterson.bsky.social · 05/03/2025
Was really looking forward to this session and it didn't disappoint! Always find related questions the hardest to answer in clinic. Just a shame they had the graveyard slot! @bopa.org.uk take note of the speakers, they would be great additions to annual conference agenda #BTOG25
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Gerry Hanna @gerryhanna.bsky.social · 05/03/2025
Well #BTOG25 that’s a wrap for 2025 from #Belfast Thanks to @btog.bsky.social for 3 fantastic years in Belfast It’s been an absolute pleasure to have the BTOG community over with us for the last 3 years 🙏 Here’s to next year in Edinburgh! @drsanjaypopat.bsky.social @tnewsomdavis.bsky.social
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Jo Evans. @oncolojo.bsky.social · 05/03/2025
With the successful role out of the TLHC programme, we now have a growing cohort of stage 1 SCLC patients. Hopefully this will become even more common, and work needed to understand optimal patient management @drjnaidoo.bsky.social #BTOG25
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Sanjay Popat @drsanjaypopat.bsky.social · 05/03/2025
Agree. A packed room for SCLC on the last day of a conference? Unheard of previously! Obviously all attending to listen to @annaminchom.bsky.social , @drjnaidoo.bsky.social ,& @stephenvliu.bsky.social! @btog.bsky.social #BTOG25
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Jo Evans. @oncolojo.bsky.social · 05/03/2025
@annaminchom.bsky.social on newer small cell therapeutic strategies and management of CRS and ICANS as specific TRAEs With thought around timings of dose delivery and education of AOS teams and patients, safely deliverable within the NHS #BTOG25
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Sanjay Popat @drsanjaypopat.bsky.social · 05/03/2025
Great job, team! @btog.bsky.social #BTOG25
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Yvonne Diaz @yvonnediaz.bsky.social · 05/03/2025
Professor @drjnaidoo.bsky.social welcomed to the #BTOG25 stage as a Lung Cancer Legend & doesn’t disappoint. Lots of discussion on how we turn discussions on Small Cell Lung Cancer on its head. Lots of optimism in #SCLC coming from new standards & future treatments. #LCSM
Photo of Dr Naidoo on stage Dr Naidoo presenting conclusionsCompares future to various movies
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DrLJ @drlaurajane.bsky.social · 05/03/2025
At #BTOG25 & I tringied by Matt’s comment on the fact that GP practices who request more chest X-rays have less stage III/IV #lungcaner disease? Read more here! www.respiratoryfutures.org.uk/features/dia...
respiratoryfutures.org.uk
Diagnosing Lung Cancer: X-rays & CT Scans | Respiratory Futures
Learn how chest x-rays and CT scans aid in diagnosing lung cancer and the role of primary care in early detection.
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DrLJ @drlaurajane.bsky.social · 05/03/2025
We really need to make sure people know this!! It’s never too late to quit smoking. Treating tobacco dependence is cancer treatment! We would not let this survival benefit pass us by of this was a new oncology drug. #BTOG25
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Chloe Waterson @chloewaterson.bsky.social · 05/03/2025
So what's the point in quitting smoking once you've already been diagnosed with cancer? Quitting in the first 6 months could add extra years to survival! #BTOG25
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Jo Evans. @oncolojo.bsky.social · 05/03/2025
@stephenvliu.bsky.social on excitement in the Small Cell arena. PDL1/PD1 inhibition a practice changer, but so many potential game changers on the horizon from BITES To ADC, it’s exciting to see new drugs for an area of unmet need #BTOG25
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Jo Evans. @oncolojo.bsky.social · 05/03/2025
@drjnaidoo.bsky.social on the limited stage small cell space and the excitement around CCRT-Durvalumab. EAMS currently open in England… #BTOG25
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Jo Evans. @oncolojo.bsky.social · 05/03/2025
Small cell in never smokers. On the rise for unknow reasons and a different biology. Having recently encountered my first patient who’s a never smoker(and no alcohol or recreational drugs), with extensive stage disease this insight is fascinating @stephenvliu.bsky.social #BTOG25
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Jo Evans. @oncolojo.bsky.social · 04/03/2025
@drsanjaypopat.bsky.social ! The OG!!! #BTOG25 @btog.bsky.social
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BTOG @btog.bsky.social · 05/03/2025
We are delighted to announce that the 2025 BTOG Lifetime Achievement Award has been presented to Professor Cindy Billingham. The announcement was made by Professor Gary MIddleton and hosted at the 23nd BTOG Annual Conference in Belfast by Professor @drsanjaypopat.bsky.social #BTOG25 #LCSM
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Oncogene Cancer Research @oncogenecancer.bsky.social · 05/03/2025
Historic moment at #BTOG25 at last evening’s dinner where Professor @drsanjaypopat.bsky.social finished his 13 year tenure as BTOG Chair & heralded the great progress. The reigns (& clapper) hv now been handed to Dr @tnewsomdavis.bsky.social. Patient advocates grateful for progress & keen for more
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Tom Newsom-Davis @tnewsomdavis.bsky.social · 04/03/2025
Fun #BTOG25 fun-run fun Excellent turnout by the hardier / insane delegates
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Jo Evans. @oncolojo.bsky.social · 04/03/2025
Sandi Deans in delivering a 14 day genomics service, and the impact of the ctDNA pilots and roll out in potential time saving. CtDNA now pending addition to the Directory @BTOG25
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Jo Evans. @oncolojo.bsky.social · 04/03/2025
Caught the most amazing sunrise en route to the #BTOG25 5km… there are some benefits to wandering the streets at 6:30am 🤣
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Jo Evans. @oncolojo.bsky.social · 04/03/2025
Matthew Krebs on ctDNA and moving away from confirmatory tissue testing where an informative result is present. Key number 1% VAF for determining of non-actionable mutations are informative #BTOG25
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Yvonne Diaz @yvonnediaz.bsky.social · 04/03/2025
Speed to diagnosis is key for ppl w #lungcancer- many of us are diagnosed at stage 4 when unwell. Great talk from Sandi Deans @nhsenglandldn.bsky.social Genomics at #BTOG25, illustrating the ideal pathway to reach the 14-day turnaround target in UK. Good to see ctDNA here #LCSM @btog.bsky.social
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Sanjay Popat @drsanjaypopat.bsky.social · 04/03/2025
One of the most powerful phrases heard at this conference. Bravo @alkpositiveuk.bsky.social #BTOG25 @btog.bsky.social
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DrLJ @drlaurajane.bsky.social · 04/03/2025
Out now! Faster Testing, Better Outcomes: genomic testing in #lungcancer from @uklungcancer.bsky.social Important recommendations #BTOG25
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ALK Positive Lung Cancer UK @alkpositiveuk.bsky.social · 04/03/2025
At #BTOG25, our Chair, Debra Montague, addressed: Have we lost the patient voice in genomics? #lungcancer patients must be at the heart of genomic advances. With the focus often on technology & turnaround times, this was a chance to put patient experiences at the centre of the conversation. #LCSM
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Sanjay Popat @drsanjaypopat.bsky.social · 04/03/2025
Ama amazing and packed session. Bravo to speakers and chairs! @btog.bsky.social #BTOG25
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Gerry Hanna @gerryhanna.bsky.social · 04/03/2025
My takeaways 👇 ➡️ uncertainty regarding benefit of peri-operative vs pre-op ChemoIO ➡️ EORTC guidelines give us a steer on surgical resectability ➡️ Radiotherapy and CRT being using post pre-op ChemoIO if patient no longer operable ➡️ Role of PORT needs re-examined in higher risk disease #BTOG25
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DrLJ @drlaurajane.bsky.social · 04/03/2025
There are any trials of IO at multiple parts of pathway. Neoadj, adj, period. Growing area. Complex & sometimes burdensome for patients but potential benefits. #BTOG25
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DrLJ @drlaurajane.bsky.social · 04/03/2025
Great summary of debates over what operable means, incl consensus statement & its limitations. Difficult to ascertain place of chemo-RTX in N2 disease when surgical approaches differ across centres… #BTOG25
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DrLJ @drlaurajane.bsky.social · 04/03/2025
Great presentation on risk of major CV events in patients with coronary calcification on #lungcancer screening. It matters. Next step: find out what interventions work & how to deliver equitably at scale! #BTOG25
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Jo Evans. @oncolojo.bsky.social · 04/03/2025
Debra Montague on ensuring the patient voice is not lost. The most important person in the room after all! We haven’t lost the patient voice but we all need to be better at listening! #BTOG25
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Tom Newsom-Davis @tnewsomdavis.bsky.social · 04/03/2025
Superstar #BTOG25 speakers, and the boss
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Sanjay Popat @drsanjaypopat.bsky.social · 04/03/2025
Podcast buddies at #BTOG25 @btog.bsky.social
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Sanjay Popat @drsanjaypopat.bsky.social · 04/03/2025
Podcast buddies at #BTOG25 @btog.bsky.social
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Jo Evans. @oncolojo.bsky.social · 03/03/2025
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Jo Evans. @oncolojo.bsky.social · 03/03/2025
Please do check out Roxane Chen’s (my iBSc student - a medical student) poster on pan-immune inflammation scoring and outcomes in ALK positive lung cancer. She worked so hard, and has been rewarded with the first abstract in the book, so no excuses not to engage, people! ❤️ No 1!! 🏅 #BTOG25
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