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Peter Hall

@drpeterhall.bsky.social
2.1K followers 1.2K following 130 posts

Professor of public health | translational neuroscience researcher | www.canadianbiobank.ca | uwaterloo.ca/prevention-neuroscienc…

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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 08/10/2026
Why do small dogs live longer than large dog species, and what is the biologic basis of differences in lifespan and healthspan? Epigenetics. There's a lot in the methylation pattern of dogs to explain this @science.org science.org/doi/10.1126/...
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Peter Hall @drpeterhall.bsky.social · 08/10/2026
Will A.I. Make Your Brain Lazy? Here’s What the New Research Actually Shows. www.nytimes.com/interactive/...
nytimes.com
Will A.I. Make Your Brain Lazy? Here’s What the New Research Actually Shows.
We’re starting to learn more about how the technology can change us.
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 05/08/2026
Severe Covid leads to persistent viral reactivation, with >10 different viruses noted in the first 40 days after hospital admission. Long Covid was specifically associated with reactivation of latent Anelloviridae virus @nature.com www.nature.com/articles/s41...
nature.com
Virus reactivation in acute and long COVID-19 - Nature
Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog...
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Peter Hall @drpeterhall.bsky.social · 03/08/2026
Longitudinal use of AI agents; an important issue in health-related contexts, given that the rule is ongoing / repeat engagements rather than single shot engagements. #AI www.nature.com/articles/s44...
nature.com
A framework for longitudinal health AI agents - Nature Health
This Perspective outlines the main components needed to design AI models that can assist individuals in the long-term management of their health, formalizing also the shortcomings and challenges of cu...
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Peter Hall @drpeterhall.bsky.social · 03/08/2026
Reliable (and sometimes quite substantial) birth order effects on disease risk in a study of 10 million siblings. “Birth order and disease risk across the human phenome” #birthorder www.nature.com/articles/s44...
nature.com
Birth order and disease risk across the human phenome - Nature Health
In multiple study designs involving millions of matched individuals, either between or within families, birth order determined differential associations with disease risk across 569 diseases.
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Peter Hall @drpeterhall.bsky.social · 02/08/2026
Antibodies have equally fascinating roles in brain development and degeneration, via a neuronal hyperactivity flagging process. #brain www.science.org/doi/10.1126/...
science.org
Antibodies sculpt adult brain circuits
Immune cells target hyperactive neurons to eliminate synaptic connections
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Reposted by Peter Hall
Lucas C Parra @parralab.org · 05/06/2026
Neuron–astrocyte associative memory | PNAS www.pnas.org/doi/10.1073/...
pnas.org
Neuron–astrocyte associative memory | PNAS
Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astroc...
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Reposted by Peter Hall
Earl K. Miller @earlkmiller.bsky.social · 21/05/2026
@pinotsislab.bsky.social showed that electric fields carry info and have *little or no representational drift* Beyond dimension reduction: Stable electric fields emerge from and allow representational drift doi.org/10.1016/j.ne... #neuroscience
doi.org
Redirecting
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Reposted by Peter Hall
Nature @nature.com · 15/05/2026
Antibiotics designed by AI, and other key developments in the ongoing battle against antimicrobial resistance go.nature.com/4twQntn
go.nature.com
Six key developments in the fight against antimicrobial resistance
Antibiotics designed by artificial intelligence, immunotherapy for resistant infections and other highlights from studies and trials.
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Peter Hall @drpeterhall.bsky.social · 13/05/2026
Biosecurity risks with AI? www.nature.com/articles/d41...
nature.com
AI can design viruses, toxins and other bioweapons. How worried should we be?
Scientists are debating whether to limit biological AI software to ward off threats.
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Peter Hall @drpeterhall.bsky.social · 06/05/2026
My new editorial on Long COVID at @JPrecisionMed : “Post-COVID-19 condition: A primer for precision medicine.” #longcovid www.jprecisionmedicine.org/article/S305...
jprecisionmedicine.org
Post-COVID-19 condition: A primer for precision medicine
Post-COVID-19 Condition (PCC; “long COVID”) is a post-viral syndrome evident by 8 to 12 weeks post-SARS-CoV-2 infection and lasting for months to years thereafter. PCC comprises at least one persisten...
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 30/04/2026
First randomized trial to show Ozempic reduces alcohol consumption in people seeking treatment for alcohol use disorder. Placebo-controlled, double-blind. Participants with BMI >30 kg/m2. thelancet.com/journals/lan...
thelancet.com
Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial
Semaglutide showed robust therapeutic effects in treatment-seeking participants with obesity and alcohol use disorder and this trial supports previous preclinical and clinical findings suggesting GLP-...
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Reposted by Peter Hall
Dr. Sandra Steingraber 🏳️‍🌈 @ssteingraber1.bsky.social · 25/04/2026
🧪 NEW STUDY: Link between microplastics and brain tumors 👇
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Reposted by Peter Hall
Edward Elderman @elderman.bsky.social · 16/04/2026
"New York with Moon". Georgia O'Keeffe. 1925.
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Peter Hall @drpeterhall.bsky.social · 14/04/2026
This is an excellent review of the features and predictors of long COVID + includes updates on recent and ongoing clinical trials for treatment. A very timely review given that 2025 was a banner year for important new findings pertaining to long COVID. #LongCOVID www.nature.com/articles/s41...
nature.com
Understanding the long-term neurological effects of SARS-CoV-2 infection - Nature Reviews Neurology
Post-COVID-19 condition (PCC), also known as long COVID, is a heterogeneous condition marked by persistent symptoms following acute SARS-CoV-2 infection. This Review summarizes the spectrum of neurolo...
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Reposted by Peter Hall
Canadian Covid Society @covidsociety.ca · 15/03/2026
Tonight, Canada goes teal for International Long Covid Awareness Day. Share your photo or video from one of the locations to support the long Covid community. Find a location near you: covidsociety.ca/priorities/l... 📷 Stacey Leigh (Corner Brook City Hall) #LongCovid #ILCAD2026 #LongCovidAwareness
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Peter Hall @drpeterhall.bsky.social · 08/03/2026
Social determinants associated with greater risk of paediatric long COVID. #longcovid jamanetwork.com/journals/jam...
jamanetwork.com
Social Determinants of Health and Pediatric Long COVID in the US
This cross-sectional analysis of a meta-cohort study evaluates associations between social determinants of health and odds of long COVID in children and adolescents.
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Peter Hall @drpeterhall.bsky.social · 01/03/2026
www.nytimes.com/2025/02/12/w...
nytimes.com
Ozempic Can Curb Drinking, New Research Shows (Published 2025)
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Reposted by Peter Hall
Nature Portfolio @natureportfolio.nature.com · 28/02/2026
Aged adults with extraordinary memory capacity – known as SuperAgers – exhibit a unique neurogenesis profile with a surprisingly high number of young neurons, according to a study published in Nature. 🧪 #Neuroscience
go.nature.com
Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease - Nature
Mapping of neurogenesis in human hippocampi across ages and different cognitive abilities using multiomic single-cell sequencing reveals distinct signatures between cognitive preservation and decline.
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 30/01/2026
"Our study highlights the presence of widespread neuroinflammation in the brain and increased levels of inflammatory cytokines in the plasma of individuals with post–COVID-19 active temporal lobe epilepsy.". www.science.org/doi/10.1126/...
science.org
Neuroimmune activation in temporal lobe epilepsy patients with worsening seizure following the COVID-19 pandemic: A [18F]DPA-714 PET/MR study
TSPO PET and inflammatory markers reveal spread neuroinflammation in temporal lobe epilepsy with seizure worsening after COVID-19.
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Peter Hall @drpeterhall.bsky.social · 28/01/2026
P-tau abnormalities appear in the spinal cord of CTE cases, not just the brain. This may open pathways toward in vivo biomarkers (finally!). #CTE #brain jamanetwork.com/journals/jam...
jamanetwork.com
Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy
This case-control study evaluates spinal cord pathologies associated with exposure to repetitive head impacts or chronic traumatic encephalopathy neuropathologic change in the brain among autopsied in...
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Reposted by Peter Hall
Will Stancil @whstancil.bsky.social · 24/01/2026
in case you're curious about how angry Minnesota is about ICE, it was -20 today
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 14/01/2026
Continuous glucose monitoring sensor data, with a foundation model, predicts risk of Type 2 diabetes and cardiovascular outcomes better than HbA1c New @nature.com www.nature.com/articles/s41...
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 03/01/2026
A.I. detecting early pancreatic cancer in China, based on @naturemedicine.bsky.social validation publication "I think you can 100% say AI saved their lives." gift link www.nytimes.com/2026/01/02/w...
nytimes.com
In China, A.I. Is Finding Deadly Tumors That Doctors Might Miss
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 05/12/2025
How do the metabolic waste products get cleared from our brain? And how does this process intersect with the brain's immune system? An exceptional review by @jonykipnis.bsky.social and colleagues cell.com/neuron/fullt...
cell.com
Resolving the mysteries of brain clearance and immune surveillance
This review by Kipnis et al. explores recent advances in brain fluid dynamics, emphasizing CSF flow’s role in waste clearance, the glymphatic and meningeal lymphatic systems, and neuroimmune interacti...
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Peter Hall @drpeterhall.bsky.social · 29/11/2025
Many complexities, but AI does seem to perform well in initial head-to-head tests, when using text as the medium. Text is, however, a very limited modality in relation to fluid, real-time interpersonal exchanges more typical of psychotherapy or emotional support #AI academic.oup.com/bmb/article/...
academic.oup.com
AI chatbots versus human healthcare professionals: a systematic review and meta-analysis of empathy in patient care
AbstractBackground. Empathy is widely recognized for improving patient outcomes, including reduced pain and anxiety and improved satisfaction, and its abse
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 29/10/2025
Acute and chronic viral infections, including Herpes Zoster (Shingles), Hepatitis C, HIV, CMV, influenza, and SARS-CoV-2, are linked with a substantial increased risk of cardiovascular events, from a systematic review. Figure for SARS-CoV-2 below newsroom.heart.org/news/some-ac...
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Peter Hall @drpeterhall.bsky.social · 27/10/2025
Longer survival among cancer patients may be an unexpected benefit of COVID vaccination. www.nature.com/articles/d41....
nature.com
People with some cancers live longer after a COVID vaccine
mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer ― in an unexpected way.
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Reposted by Peter Hall
Michael Okun @michaelokun.bsky.social · 14/10/2025
RIP Dr. Nolan R. Williams (1983-2025) professor at Stanford. He was a pioneer in the treatment of depression and a friend. I read this Substack eulogy on him this morning, and I thought it really captured both the man and his brilliance. thefrontierpsychiatrists.substack.com/p/a-eulogy-f...
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Peter Hall @drpeterhall.bsky.social · 16/10/2025
An up to date review on the Brian health officials impacts of exercise, with a focus on mechanism #brainhealth www.thelancet.com/journals/lan...
thelancet.com
Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing
Ageing is a scientifically fascinating and complex biological occurrence characterised by morphological and functional changes due to accumulated molecular and cellular damage impairing tissue and org...
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 10/10/2025
Waning immunity. A significant Covid wave in England. No new variant. Thanks Prof Pagel for highlighting and contextualizing
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Peter Hall @drpeterhall.bsky.social · 02/10/2025
One third???
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 01/10/2025
Our capability to prevent diseases from occurring is gaining momentum. Using A.I. to predict >1,200 diseases 20 years ahead adds to the ways we'll be able to achieve primary prevention. nature.com/articles/d41... erictopol.substack.com/p/dawn-of-a-...
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 17/09/2025
A groundbreaking paper published @nature.com today—the first large health language model—predicts >1,000 diseases for a person and when. Implications here: erictopol.substack.com/p/dawn-of-a-...
erictopol.substack.com
Dawn of A New Era of Primary Prevention in Medicine
Recent groundbreaking reports highlight our newfound potential to prevent diseases
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 16/09/2025
Coming tomorrow. Something that's been talked about for many decades, but not done. That's changing. Subscribe; it's free, and you'll get the link by email and future posts. erictopol.substack.com
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 13/09/2025
We know GLP-1 drugs reduce brain inflammation. But I didn't anticipate bipolar disorder as a possible indication in the future www.nature.com/articles/s41...
nature.com
Glucagon-like Peptide-1 receptor agonists as emerging therapeutics in bipolar disorder: a narrative review of preclinical and clinical evidence - Molecular Psychiatry
Molecular Psychiatry - Glucagon-like Peptide-1 receptor agonists as emerging therapeutics in bipolar disorder: a narrative review of preclinical and clinical evidence
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Reposted by Peter Hall
The New York Times @nytimes.com · 03/09/2025
OpenAI said on Tuesday that it planned to introduce new features intended to make its chatbot safer, including parental controls, “within the next month.”
nyti.ms
ChatGPT Will Get Parental Controls and New Safety Features, OpenAI Says
After a California teenager spent months on ChatGPT discussing plans to end his life, OpenAI said it would introduce parental controls and better responses for users in distress.
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 22/08/2025
How plasma p-Tau markers can predict if and when there will be transition to mild cognitive impairment and Alzheimer’s disease in cognitively unimpaired individuals, along staging of the disease www.nature.com/articles/s43...
nature.com
Plasma tau biomarkers for biological staging of Alzheimer’s disease - Nature Aging
Montoliu-Gaya, Salvadó et al. develop a blood-based model using tau biomarkers measured in a single analysis enabling biological staging of Alzheimer’s disease to support the diagnosis, prognosis and ...
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Reposted by Peter Hall
Doug Parr @dougparr.bsky.social · 21/08/2025
China installed 212 gigawatts of solar capacity in the first six months of the year, more than America's entire capacity of 178 gigawatts as of the end of 2024 www.independent.co.uk/news/china-a...
independent.co.uk
China rushes to build out solar, and emissions edge downward
Chinese officials have showcased what they claim will be the world's largest solar farm on the Tibetan plateau
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Reposted by Peter Hall
Sara Margarita Medina Ramos @sarammedinaramis.bsky.social · 20/08/2025
COVID Vaccine for children
reuters.com
US pediatric group breaks with federal policy, recommends COVID vaccines for young children
The American Academy of Pediatrics on Tuesday recommended that all young children get vaccinated against COVID-19, differing from federal policy that no longer recommends routine vaccination for healthy children.
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Peter Hall @drpeterhall.bsky.social · 13/08/2025
Naturally occurring dementia analog in cats may turn out to be a good model for humans. #dementia www.the-independent.com/life-style/h...
the-independent.com
Cats develop dementia in a similar way to humans, study finds
The breakthrough was hailed as a “perfect natural model for Alzheimer’s” by scientists who worked on it
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 07/08/2025
For #ME/CFS, genomics assessed in >15,000 indviduals with 8 genomic loci identified. "Validation of ME/CFS as a biomedical condition and an important corrective to psychologizing ‘all in the mind’ perspectives on the disease” www.science.org/content/arti... www.research.ed.ac.uk/en/publicati...
science.org
Possible genetic clues to ME/chronic fatigue syndrome identified in massive study
DNA analysis of more than 15,500 people with the debilitating condition identifies eight tentative “genetic signals”
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Reposted by Peter Hall
Eric Topol @erictopol.bsky.social · 03/08/2025
A rundown on the big advances we’re seeing on the brain-immune axis erictopol.substack.com/p/our-braini...
erictopol.substack.com
Our Brain—Immune Axis Gets A Jolt
Facts, data and analytics about biomedical matters
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Peter Hall @drpeterhall.bsky.social · 30/07/2025
I’m floored … this is pretty astounding. #SARS-CoV-2 #Covid19
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Peter Hall @drpeterhall.bsky.social · 30/07/2025
Infection-related visual stimuli are enough to prime the immune response via the brain #immune #brain www.nature.com/articles/s41...
nature.com
Neural anticipation of virtual infection triggers an immune response - Nature Neuroscience
Serino et al. show that seeing an infectious avatar approach the body in virtual reality triggers an immune response, indicating that the brain prepares the body to fight infections even for perceived...
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Reposted by Peter Hall
Martin Alan @martinalan.bsky.social · 25/07/2025
Enjoying the silence. #summermorning #enjoythesilence #summer #nature #silhouette #sunrise
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Peter Hall @drpeterhall.bsky.social · 25/07/2025
www.bbc.co.uk/news/videos/...
bbc.co.uk
The story behind the photograph of a starving Gaza baby
Photographer Ahmed al-Arini told BBC Newshour he had to catch his breath between each photograph.
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Peter Hall @drpeterhall.bsky.social · 24/07/2025
Oh my god, this has to stop. Let the trucks in… www.theguardian.com/world/live/2...
theguardian.com
People in Gaza are ‘walking corpses’, says Unrwa, as agency says it has 6,000 aid trucks ready to enter – Middle East crisis live
Philippe Lazzarini says Unrwa findings show one in five children is malnourished in Gaza City and says agency has food and medical supplies
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Peter Hall @drpeterhall.bsky.social · 20/07/2025
Even in post-secondary, we are seeing some highly misogynistic language popping up in online venues, with little to no moderation. Definitely not helping the situation, as it maintains an illusion of endorsement or credibility. www.cbc.ca/news/canada/...
cbc.ca
Online misogyny seeping into classrooms in 'frightening' ways, teachers and experts say | CBC News
A Dalhousie researcher has found misogynistic comments from students are disrupting  learning environments as teachers deal with degrading remarks and male-supremacist sentiments.
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Reposted by Peter Hall
Prof Sarah-Jayne Blakemore @sjblakemore.bsky.social · 16/07/2025
I was explaining to my Ukrainian colleague the phrase ‘There’s no such thing as a free lunch’. She told me the equivalent in Ukrainian is ‘The only free cheese is in the mousetrap’ - which is so much better
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