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Don Sharkey

@donsharkey.bsky.social
277 followers 125 following 59 posts

Prof of Neonatal Medicine & Technologies @Uni Nottingham. Views my own. Neonatal technologies & transport research.

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Don Sharkey @donsharkey.bsky.social · 01/10/2026
Amazing, well done all. Looking forward to 👀 results, next week 😉?
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Don Sharkey @donsharkey.bsky.social · 04/09/2026
Fascinating work.
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Don Sharkey @donsharkey.bsky.social · 02/09/2026
www.bapm.org/events/bapm-... only 2 weeks to go to the 50th anniversary annual conference of @bapmofficial.bsky.social . Super excited as being held in our very own @uniofnottingham.bsky.social . Our group will be presenting some exciting research we believe will shape practice....
bapm.org
BAPM Annual Conference 2026
Working Together to Shape the Future of Perinatal Care.
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Don Sharkey @donsharkey.bsky.social · 13/08/2026
It happens to us all!
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Don Sharkey @donsharkey.bsky.social · 09/08/2026
This signal suggests larger adequately powered (90%) studies are required especially in low resource settings where treatment is harder and burden of visual impairment greater. Safety data will be crucial inc. eye infections.
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Don Sharkey @donsharkey.bsky.social · 06/08/2026
www.science.org/doi/10.1126/... Interesting preclinical study. Perhaps has implications for term HIE & preterm brain injury repair? One for newborn brain researchers to consider? @jamespboardman.bsky.social @atulmalhotra.bsky.social @ela-chakk.bsky.social @braintherapies.bsky.social @science.org
science.org
Adenosine 2A receptor drives microglial efferocytosis to accelerate white matter repair and functional recovery after stroke
Stimulating the efferocytosis of cellular and myelin debris by microglia after stroke promotes remyelination.
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Don Sharkey @donsharkey.bsky.social · 29/07/2026
Interesting how the two studies (www.nejm.org/doi/full/10....) @nejm.org were very similar but powered very differently. Hopefully an planned IPMA will come next but I'd say the writing is on the wall for EPO. Where next, melatonin? @ebneo.bsky.social
nejm.org
Trial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns | NEJM
Neonatal hypoxic–ischemic encephalopathy is an important cause of death as well as long-term disability in survivors. Erythropoietin has been hypothesized to have neuroprotective effects in infants...
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Don Sharkey @donsharkey.bsky.social · 27/07/2026
Small but crucial gains, we suspected this but great to see in RCT. Also fabulous to see @jama.com publishing trials in these populations.
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European Society for Paediatric Research (ESPR) @espr-esn.bsky.social · 22/07/2026
Only 2 of 38 EU health research calls explicitly include children. It’s time to change that. Read the joint white paper from EAP, ESPR, AEPC, ESPE and ESPGHAN and help make child health a research priority. 🔗 www.eurospe.org/wp-content/u...
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Don Sharkey @donsharkey.bsky.social · 14/07/2026
Factor in pregnancy and this becomes even harder to understand for babies exposed (or not)....
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Don Sharkey @donsharkey.bsky.social · 14/07/2026
Thanks. May not have spotted this one without excellent @ebneo.bsky.social summary. Will now hunt it out....
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Don Sharkey @donsharkey.bsky.social · 11/07/2026
www.bbc.co.uk/news/article... what an inspiring story, if we had more Harchie's we'd be turning our use of technologies for the good and less about profit and destruction.
bbc.co.uk
Lab named after teenager who helped improve tech for disabled
Harchie Sagoo, who had cerebral palsy, was a key product tester for Bristol-based Smartbox.
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Don Sharkey @donsharkey.bsky.social · 05/06/2026
@espr-esn.bsky.social
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Don Sharkey @donsharkey.bsky.social · 05/06/2026
Finally awarded the neonatal transport grant I've been building for 5yrs. 🙏 @ukri.org for funding our team £1.5 million ($2M) to finally make interhospital transfer safer for all babies and provide the research community with next generation research tools to accelerate Neonatal Transport care.
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Don Sharkey @donsharkey.bsky.social · 26/05/2026
The info graphic suggests both groups received high drug delivery devices, is this a typo or have I misinterpreted @jamapediatrics.com ?
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European Society for Paediatric Research (ESPR) @espr-esn.bsky.social · 22/05/2026
The interactive scientific programme of our 2026 international meeting @cepascongress.bsky.social together with EAP & in collab. with GFCNI is live. Explore session details, confirmed talks & speakers! Kindly supported by @99nicu.bsky.social & @ebneo.bsky.social. More: www.cepas.org/scientific-p...
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The BMJ @bmj.com · 20/05/2026
This Analysis for The BMJ Commission on the Future of Academic Medicine proposes reforms to rebuild the clinical academic pipeline www.bmj.com/content/393/...
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Don Sharkey @donsharkey.bsky.social · 18/05/2026
www.nature.com/articles/s41... Wow, eco friendly house in rural Africa massively reduces malaria, diarrhoea, respiratory infections and improves pre-school children height. Fabulous work, pharma has its place but this is outstanding. Perhaps an approach to consider aid differently rather than cuts.
nature.com
A sustainable house design to improve child health in rural Africa: a cluster-randomized controlled trial - Nature Medicine
A cluster-randomized trial in rural Tanzania showed that a sustainable housing design reduced incidences of malaria, diarrhea, acute respiratory infections and stunting in children under 5 years of ag...
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Don Sharkey @donsharkey.bsky.social · 16/05/2026
Done 😀
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Don Sharkey @donsharkey.bsky.social · 13/05/2026
This is a huge effect size. Congratulations translating this into clinical trials.
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Don Sharkey @donsharkey.bsky.social · 29/04/2026
Fascinating, would be good to understand the implications for preterm birth, nutrition of the preterm infant and impact on outcomes. One for you @jamespboardman.bsky.social
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The BMJ @bmj.com · 13/04/2026
Data used to justify the expansion of controversial software in the NHS is flawed, experts say, and the pilot trust’s innovation adviser worked directly for Palantir bit.ly/4stVolW
bmj.com
Palantir: NHS pilot’s “success” is questioned as second figure at major trust is linked to the tech giant
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The Lancet @thelancet.com · 10/04/2026
"Every 1% increase in military spending drives a 0·62% reduction in public health spending." On the cover, a new letter examines the relationship between military spending and public health expenditure during conflicts. Find out more in our latest issue: spkl.io/63325ANG6W
Cover of The Lancet's April 11, 2026 issue. Quote on cover reads: "Health cannot—and should not—be overlooked in the economies of war."
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Don Sharkey @donsharkey.bsky.social · 10/04/2026
Some important messages in this 1 minute read.
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SurePulse @surepulsemedical.bsky.social · 17/03/2026
Dr James Carpenter will present our new multi-parameter, wireless, vital sign monitoring for newborns to an audience of 90+ investors, strategics, clinicians, and industry leaders helping shape the future of medtech. #MedTechInnovator #MTIRadarForum
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Don Sharkey @donsharkey.bsky.social · 06/03/2026
Intriguing!
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Don Sharkey @donsharkey.bsky.social · 15/02/2026
Shocking data.
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European Society for Paediatric Research (ESPR) @espr-esn.bsky.social · 13/01/2026
Join us at the 17th Dresden Symposium on Feto-Neonatal Health & ESN Spring School under the leadership of ESPR Senior Member Prof Mario Rüdiger!📍 Dresden, 12-14 March.📅 Thu–Fri: cutting-edge talks; 🛠 Sat: hands-on workshops, incl. ESN NPE training. See the full programme here: tinyurl.com/3rhz4cuy
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NeoTRIPs @handle.invalid · 29/12/2025
The next NeoTRIPs Lunch & Learn! 🧬 Clinical Genetics in Neonatal Medicine 🗓️ Friday 23rd January 12-2pm 🎟️ Register with your work email here: neotrips.org/event/neotri...
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Don Sharkey @donsharkey.bsky.social · 10/12/2025
@plos.org
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Don Sharkey @donsharkey.bsky.social · 10/12/2025
journals.plos.org/digitalhealt... New paper out today from @tngchang.bsky.social from University of Nottingham with many collaborators (thanks). Excellent OA online extreme preterm mortality prediction tool with neat explainable element. Great for all perinatal teams.
journals.plos.org
Developing and validating an explainable digital mortality prediction tool for extremely preterm infants
Author summary Increasingly, more premature babies are being born even earlier and surviving. Each premature baby is unique, with different combinations of factors affecting their chances of survival....
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European Society for Paediatric Research (ESPR) @espr-esn.bsky.social · 24/11/2025
🚀Calling all neonatal & paediatric researchers! Submit your abstract for #CEPAS2026 in Lyon (28–31 Oct) by 1 Apr 2026. Share your innovations, gain skills, and connect globally to shape the future of child health! www.cepas.org/abstracts?ut...
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Don Sharkey @donsharkey.bsky.social · 23/10/2025
I've seen the published data on this which are worrying. I'm less convinced of the causal suggestion but certainly more work could tease thar out. Having a plastic tube in your trachea/bloodstream/GI tract for months may not be without hidden issues.
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ambaln.bsky.social @ambaln.bsky.social · 30/09/2025
Our BiB trial manuscript now published in JAMA...Early Intratracheal Budesonide for Bronchopulmonary Dysplasia url: jamanetwork.com/journals/jam...
jamanetwork.com
Early Intratracheal Budesonide for Bronchopulmonary Dysplasia
This randomized clinical trial conducted at centers of the United States Neonatal Research Network assesses whether early intratracheal administration of a combination of budesonide mixed with surfact...
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NIHR HealthTech Research Centre in Paediatrics and Child Health @nihrhrcchildren.bsky.social · 29/09/2025
Our September newsletter is now available! Read this month's issue here for news, upcoming events, funding opportunities and recent publications in child health 👉 mailchi.mp/d56096f82afc...
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NEJM.org @nejm.org · 25/09/2025
Editor-in-Chief Eric Rubin asks why, under an administration that says it is focused on making America healthy again, we are denigrating and discarding our single most cost-effective public health tools — vaccines. Read the full editorial: nej.md/4mtH8Xm #MedSky #PublicHealth
Editorial 
"Under an administration that says it is focused on making America healthy again, why are we denigrating and discarding our single most cost-effective public health tools?" 

"Risk and Benefit" by Eric J. Rubin, M.D., Ph.D.
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Don Sharkey @donsharkey.bsky.social · 23/09/2025
Sad to see this come to fruition. @stefanjohansson.nicuverse.org.ap.brid.gy your analysis gets a mention but despite the strengths it is dismissed...😔
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Don Sharkey @donsharkey.bsky.social · 20/09/2025
Great to see neonatal studies of this type being published in JAMA.
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Don Sharkey @donsharkey.bsky.social · 16/09/2025
Very thorough review and highlights early challenges FGR infants need to overcome. As highlighted, tricky to identify who truly is FGR vs constitutionally small.
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Don Sharkey @donsharkey.bsky.social · 15/09/2025
Early days but a promising approach. Likely to be more challenging in my population of newborn infants but would be great to explore....
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Don Sharkey @donsharkey.bsky.social · 15/09/2025
Interesting approach.
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Don Sharkey @donsharkey.bsky.social · 12/09/2025
The link doesn't work
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Don Sharkey @donsharkey.bsky.social · 04/09/2025
Some great baseline data to see how RSV prophylaxis works out in coming years.
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Don Sharkey @donsharkey.bsky.social · 04/09/2025
Very nice. Agree, neonatology should not follow the historical approach of "one size fits all", we moved past that long ago and need to personalise treatments for the infant in front of us.
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Don Sharkey @donsharkey.bsky.social · 04/09/2025
You can't beat some baby feet to grab your attention and make you read!
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Don Sharkey @donsharkey.bsky.social · 29/08/2025
I've listened to almost all of these and they are great. Chatting about neonatal research and care. Well worth a listen for all involved in the care of newborns. Good work Mario and @espr-esn.bsky.social
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Don Sharkey @donsharkey.bsky.social · 11/08/2025
Really interesting study pushing the boundaries on this tricky and often poor outcome condition. Perhaps a condition that one day will have a handful of centres with expertise to treat and hopefully improve outcomes.
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Chris Kotanidis @cpkotanidis.bsky.social · 31/07/2025
The win ratio method is gaining traction in #RCTs. Is it just a trend or a smarter way to look at composite hierarchical outcomes? We break it down in our latest Stats, STAT!📊 in NEJM Evidence. youtube.com/watch?v=jKtF... #stats @nejm.org @sarahgorey.bsky.social @chardin.bsky.social @ai.nejm.org
youtube.com
How Win Ratios Work | NEJM Evidence
YouTube video by NEJM Group
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Stephen Wardle @stevewardle.bsky.social · 23/07/2025
www.nottinghampost.com/news/notting...
nottinghampost.com
Mum of 'miracle' baby on the pioneering surgery which saved her life
The procedure prevented an extremely premature birth and the baby is now doing well
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NEJM.org @nejm.org · 23/07/2025
Ivermectin is an antiparasitic drug that kills mosquitoes feeding on treated persons. In this trial in Kenya, ivermectin given once per month for 3 months led to a 26% lower incidence of malaria than albendazole. Full trial results: nej.md/4lIyNzB #MedSky #IDSky
A graph showing the crude cumulative incidence of malaria infection in the 6 months after the start of three monthly rounds of mass administration of ivermectin at a dose of 400 μg per kilogram of body weight, as compared with albendazole at a dose of 400 mg.
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