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Chris Kotanidis

@cpkotanidis.bsky.social
42 followers 31 following 11 posts

Clinical Lecturer in Cardiology at Oxford | Former Editorial Fellow at New England Journal of Medicine | PostDoc at Harvard Med | DPhil University of Oxford | MD Aristoteleio

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Reposted by Chris Kotanidis
American Journal of Preventive Cardiology @ajpcardio.bsky.social · 19/06/2026
🧬 Can AI predict heart attack risk in psoriasis patients better than traditional tools? MetaPsoAI found a 3.6× higher risk, validated in 274,000 UK Biobank participants. 🔗 www.sciencedirect.com/science/artic… #Psoriasis #PreventiveCardiology #CardioSky #MedSky
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Reposted by Chris Kotanidis
American Society for Preventive Cardiology @aspcardio.bsky.social · 10/06/2026
The countdown is on. 🫀 Hear from Congress Chair David Maron, MD, FASPC, on what makes #ASPC2026 the premier meeting in cardiovascular disease prevention! 📅 July 31 – August 2 📍 The Phoenician, Scottsdale, AZ www.aspconline.org/events/2026c... #CardioSky #MedSky @ajpcardio.bsky.social
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 11/03/2026
For a patient with hypertension, would you recommend a systolic blood-pressure target of less than 120 mm Hg and or a target of less than 140 mm Hg? Vote on the best option: nej.md/4sr0SP0  #MedSky #CardioSky
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Chris Kotanidis @cpkotanidis.bsky.social · 14/01/2026
I want to thank my co-authors Hélène Eltchaninoff, Elaine Tseng & Vinod Thourani, who argue pros and cons for this interesting vignette in our latest #NEJM Clinical Decisions. Read the full discussion below and cast your vote. @nejm.org @ai.nejm.org
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Chris Kotanidis @cpkotanidis.bsky.social · 10/09/2025
#GLP1s have transformed #obesity care, but can they compete with surgery? #AMichaelLincoff & #ScottShikora argue the pros and cons of #semaglutide vs #bariatricsurgery for a man with obesity in our @nejm.org Clinical Decisions www.nejm.org/doi/full/10....
nejm.org
Managing Obesity | NEJM
This feature about a man with obesity offers a case vignette accompanied by two essays, one supporting initiation of semaglutide therapy and the other recommending bariatric and metabolic surgery.
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Reposted by Chris Kotanidis
Radcliffe Department of Medicine @rdm.ox.ac.uk · 08/09/2025
Congratulations to Dr Christos Kotanidis who has been awarded the 2025 ESC Young Investigator Award in Preventative Cardiology at the European Society of Cardiology Congress in Madrid. Read more 👇 shorturl.at/KU2Be
shorturl.at
Christos Kotanidis wins ESC Young Investigator Award 2025 in Preventive Cardiology
Congratulations to Dr Christos Kotanidis, NIHR-funded Academic Clinical Lecturer in Cardiology, who has been awarded the 2025 ESC Young Investigator Award in Preventive Cardiology at the European Soci...
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Chris Kotanidis @cpkotanidis.bsky.social · 08/09/2025
www.rdm.ox.ac.uk/news/christo...
rdm.ox.ac.uk
Christos Kotanidis wins ESC Young Investigator Award 2025 in Preventive Cardiology
Congratulations to Dr Christos Kotanidis, NIHR-funded Academic Clinical Lecturer in Cardiology, who has been awarded the 2025 ESC Young Investigator Award in Preventive Cardiology at the European Soci...
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Reposted by Chris Kotanidis
Peer Review Congress #PRC11 Coming 2029! @peerreviewcongress.bsky.social · 05/09/2025
#ZakKohane on #AI in #PeerReview: the surge in scientific publication is straining the conventional review system beyond capacity. @ai.nejm.org piloting AI-augmented fast track review: manuscripts w high prior of being good gets assigned to #GPT5 + a human, disposition reviewed by editorial team!
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Reposted by Chris Kotanidis
Peer Review Congress #PRC11 Coming 2029! @peerreviewcongress.bsky.social · 04/09/2025
Comparing submitted vs published RCT abstracts eval'd at @nejm.org in 4 domains (design, outcome, AEs, conclusions). published abstracts improved in a mean 0.9 domains. More improvements observed in leading gen med vs 433 other journals (72 % vs 48%) www.acpjournals.org/... @cpkotanidis.bsky.social
Our comparisons of submitted and published abstracts suggest that peer review and editorial processes result in substantial revision of research reports. The findings reinforce the importance of editorial oversight in scientific publishing, highlighting its role in refining study design communication, reporting of outcomes, and overall clarity in research dissemination.
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Reposted by Chris Kotanidis
Sarah Gorey @sarahgorey.bsky.social · 04/09/2025
Well done @cpkotanidis.bsky.social ! Also check out our manuscript in @annalsofim.bsky.social url.us.m.mimecastprotect.com/s/kNYpCDkAO2...
url.us.m.mimecastprotect.com
ACP Journals
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Chris Kotanidis @cpkotanidis.bsky.social · 29/08/2025
Excited to present our work tomorrow on a novel #AI #metabolomics score to predict #cardiovascular risk in #psoriasis at the #ESCCongress #WCCardio 2025 Young Investigator Award session in Preventive Cardiology. #PreventiveCardiology #CardioRheumatology #YIA
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 29/08/2025
Four Original Articles were simultaneously published in NEJM and presented earlier today at this year’s #ESCCongress in Spain. @escardio.bsky.social
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Reposted by Chris Kotanidis
Eric Topol @erictopol.bsky.social · 29/08/2025
The #1 cause of death in women is heart disease. A new report makes the case for treating women with statins who have a high inflammation marker (hs-CRP) but no traditional risk factors academic.oup.com/eurheartj/ad...
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Reposted by Chris Kotanidis
European Society of Cardiology @escardio.bsky.social · 29/08/2025
🎥 Snackable Science from #ESCCongress 2025 in Madrid! Roxana Mehran & Michael Gibson break down the new Focus Update of the 2019 #ESCGuidelines on #dyslipidaemias with the latest recommendations you need to know 👇
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 15/08/2025
For a man with #obesity, would you recommend the initiation of semaglutide therapy or bariatric and metabolic surgery? Read the case vignette and essays on both treatment options and cast your vote: nej.md/3HiAnJz #MedSky #EndoSky
Clinical Decisions 
Managing Obesity 
Christos P. Kotanidis, M.D., D.Phil., A. Michael Lincoff, M.D., and Scott A. Shikora, M.D. 

An illustration of the man walking his dog
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Chris Kotanidis @cpkotanidis.bsky.social · 31/07/2025
The win ratio method is gaining traction in #RCTs. Is it just a trend or a smarter way to look at composite hierarchical outcomes? We break it down in our latest Stats, STAT!📊 in NEJM Evidence. youtube.com/watch?v=jKtF... #stats @nejm.org @sarahgorey.bsky.social @chardin.bsky.social @ai.nejm.org
youtube.com
How Win Ratios Work | NEJM Evidence
YouTube video by NEJM Group
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Reposted by Chris Kotanidis
CORE IM @coreimpodcast.bsky.social · 25/06/2025
1/ 🚨 NEW #BeyondJournalClub w/ @nejm.org: REDUCE-AMI What is the long term benefit of beta blockers in patients with preserved EF following an MI? 🖥️: www.coreimpodcast.com/2025/06/25/b...
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Reposted by Chris Kotanidis
JAMA Internal Medicine @jamainternalmed.com · 24/06/2025
In older patients with acute coronary syndrome, an early invasive strategy did not reduce all-cause mortality but decreased recurrent myocardial infarction and repeated revascularization. ja.ma/40hDK9G
Early Invasive or Conservative Strategies for Older Patients With Acute Coronary Syndromes
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 13/06/2025
What is it like to be an NEJM editorial fellow for a year? This year’s fellows discuss what they have learned, how their experience will help their career, and what surprised them. Apply for the 2026–27 NEJM editorial fellowship by August 1. Learn more: nej.md/3cCQajB #MedSky #MedEd
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 14/06/2025
60-Second Journal Club: The SUMMIT trial examined cardiovascular outcomes of treatment with tirzepatide in patients with heart failure with preserved ejection fraction and obesity. Read the full trial results: nej.md/4hRGaTY #MedSky #CardioSky @cpkotanidis.bsky.social‬
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 09/06/2025
A 73-year-old woman presented with severe chest pain. She had undergone multivessel percutaneous coronary intervention 2.5 years earlier. Angiography revealed a large thrombus in an LAD artery stent (shown in videos). Read the full case details: nej.md/4jC2aSa #MedSky #CardioSky
Aspiration Thrombectomy for Coronary Stent Thrombosis 

Panel A: Coronary angiography revealing a large thrombus in the LAD artery stent. 
Panel B: The thrombus that was removed with the use of an aspiration catheter. 
Panel C: The stent that was dilated with a balloon at high pressure, which resulted in improved flow.
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Reposted by Chris Kotanidis
Sarah Gorey @sarahgorey.bsky.social · 06/05/2025
Really enjoying @cpkotanidis.bsky.social’s fascinating presentation on his interesting work at @brighamandwomens.bsky.social on identifying risk markers of CVD in patients with IMIDs 🤩👏👏👏
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Chris Kotanidis @cpkotanidis.bsky.social · 22/04/2025
New research alert: Our latest report highlights a significant reduction in coronary #inflammation and residual inflammatory risk as captured by #CCTA imaging using CaRi-Heart AI in women with #BreastCancer 2 years post-RT #AI #CardioOncology #CardioEd #EHJ @escardio.bsky.social
academic.oup.com
Coronary inflammation and cardiovascular risk in breast cancer after radiotherapy
Radiotherapy (RT) is known to reduce the rate of disease recurrence following breast-conserving surgery in patients with breast cancer, but also entails ir
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 30/03/2025
Presented at #ACC25: In the PROTECT-TAVI trial, the routine use of cerebral embolic protection during TAVI did not reduce the incidence of stroke within 72 hours or before discharge from the hospital (if discharge occurred sooner). Full trial results: nej.md/41RONXi @accintouch.bsky.social
nej.md
Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation | NEJM
Transcatheter aortic-valve implantation (TAVI) is associated with procedure-related stroke. Cerebral embolic protection (CEP) devices may reduce embolization to the cerebral circulation and hence t...
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Chris Kotanidis @cpkotanidis.bsky.social · 26/03/2025
Ever wondered how interim analyses work in #RCTs? 📊 Check out our Stats, STAT! video at NEJM Evidence: @nejm.org @ai.nejm.org @sarahgorey.bsky.social evidence.nejm.org/doi/full/10.... #MedStats #ClinicalTrials
evidence.nejm.org
How Interim Analyses Work
This Stats, STAT! animated video explores interim analyses in clinical trials. During these evaluations of the data, researchers may assess safety, efficacy, and verify sample size assumptions, but...
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 08/03/2025
Tirzepatide was previously shown to provide sustained weight reductions in adults with #obesity. Longer-term findings in adults with both obesity and prediabetes are summarized in a new Quick Take video. youtu.be/c9uazgSdDJc #MedSky #EndoSky
youtu.be
- YouTube
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
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Chris Kotanidis @cpkotanidis.bsky.social · 07/03/2025
🫀New research🫀 Across 6 #RCTs (n=2,257) early invasive management in #female patients with #NSTEACS did not reduce all-cause mortality or MI risk at 6 months vs. delayed management. #AHAJournals @drroxmehran.bsky.social @vijaykunadian.bsky.social www.ahajournals.org/doi/10.1161/...
ahajournals.org
Early Versus Delayed Invasive Management of Female Patients With Non–ST-Elevation Acute Coronary Syndrome: An Individual Patient Data Meta-Analysis | Circulation: Cardiovascular Interventions
BACKGROUND: Female patients are at greater risk of adverse events following non–ST-elevation acute coronary syndrome but less frequently receive guideline-recommended coronary angiography and revascul...
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 05/03/2025
In the HELIOS-B trial, researchers assessed the efficacy and safety of vutrisiran in patients with transthyretin amyloidosis with cardiomyopathy. NEJM Editorial Fellow Christos Kotanidis, MD, DPhil, summarizes the results. Full trial: nej.md/3X5nl5Q #MedSky #CardioSky @cpkotanidis.bsky.social
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Reposted by Chris Kotanidis
NEJM.org @nejm.org · 03/03/2025
In a new editorial, NEJM Editor-in-Chief Eric J. Rubin, MD, PhD, comments on the effects of the raft of executive orders from the current administration on scientific research and public health. Read the full editorial: nej.md/4gXeRFW #MedSky
EDITORIAL 
“What can we do to counter the current chaos? At the least, we can try to maintain order. In our roles as editors, this means continuing to do what we think makes a difference: publishing the highest-quality research, analysis, opinion, and educational content that can improve patient health.” 

“Order out of Chaos” by NEJM Editor-in-Chief Eric J. Rubin, M.D., Ph.D.
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Chris Kotanidis @cpkotanidis.bsky.social · 27/02/2025
🤔Recurrent severe abdominal pain with no clear cause? In the latest #NEJMDoubleTake we unpack a perplexing case with a broad differential, key clinical clues, and a surprising diagnosis. 🎥🩺 🏥🔬 nejm.org/doi/full/10.... @nejm.org
nejm.org
A Swell Diagnosis | NEJM
This Double Take video explores the differential diagnosis for a man with recurrent severe diffuse abdominal pain without obvious associated symptoms and reviews how the diagnosis evolves with new ...
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