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Anca M. Hrastinski, MD (former Pasca)

@braintherapies.bsky.social
1.1K followers 1.9K following 44 posts

Neonatologist and scientist using organoids to study neonatal brain development and injury. www.BrainTherapeuticsLab.org

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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 18/09/2026
Super cool for biological discovery and biologically-informed drug development!
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Reposted by Anca M. Hrastinski, MD (former Pasca)
Stella Hurtley @smhsci.bsky.social · 18/09/2026
Out now in @science.org Multi-organelle signatures map cell-state diversity and metabolic adaptation in tissues | Science www.science.org/doi/10.1126/...
science.org
Multi-organelle signatures map cell-state diversity and metabolic adaptation in tissues
Cell-state diversity drives tissue adaptability, repair, and disease resilience, but capturing this complexity is a challenge. Current approaches rely on transcriptional profiling and overlook organel...
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 15/09/2026
As a #StemCells and #Organoid enthusiast, but also in my new role as expert advisor 😍 for the  Consortium on Advanced Stem Cell-Based Models in Drug Discovery and Development, I am truly looking forward to this amazing event: www.isscr.org/upcoming-pro...
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 25/05/2026
Goodreads alert from our team: Adrenomedullin Restores Mitochondrial Bioenergetics and Rescues Interneuron Phenotypes in Human Models of 22q11.2 Deletion Syndrome. www.biorxiv.org/content/10.6... Same Adrenomedullin that rescues interneuron migration in hypoxia in Puno at al, eLife, 2026!
biorxiv.org
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Reposted by Anca M. Hrastinski, MD (former Pasca)
Eric Topol @erictopol.bsky.social · 31/10/2025
We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word www.scripps.edu/news-and-eve...
scripps.edu
Scripps Research scientists launch new digital clinical trial to test repurposed drug for long COVID symptom relief
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 03/10/2025
Celebrated our paper: We show that supporting, rather than suppressing, some cellular responses to hypoxia can be neuroprotective. Sometimes, hypoxia markers are not just biomakers, but therapeutic avenues. Tks @elife.bsky.social for supporting unconventional ideas elifesciences.org/reviewed-pre...
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Reposted by Anca M. Hrastinski, MD (former Pasca)
Ruth Huttenhain @rhuttenhain.bsky.social · 02/10/2025
My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology: postdocs.stanford.edu/prospective/... #TeamMassSpec #Proteomics #GPCR #Postdoc
postdocs.stanford.edu
Open Postdoctoral position, faculty mentor Ruth Huttenhain | Office of Postdoctoral Affairs
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 19/08/2025
Had dinner at Buck’s of Woodside! This restaurant is sooo unique! Here is one of the things they had on display 😂
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 25/07/2025
My first experience as an #NIH reviewer was extremely gratifying and honestly life changing. I only wish I would have done it sooner…much sooner! Junior PIs: this should be TOP on your priority list! No joke!
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 26/06/2025
We are in the latest stages of submitting a major revision. I worked in the Neonatal ICU for 2 weeks #exhausted Me: send me your manuscript, I will review it on the plane. Lab member: No, you are taking a few days off this weekend. I am not sending you anything. #LabGoals
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 11/04/2025
New parenting level unlocked: kids self-sufficient at a water park! #glorious
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 19/03/2025
6th grade math problems challenging sometimes? ChatGPT to the rescue…with step by step explanations
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 13/03/2025
Thank you @stanford-chemh.bsky.social for this 😍 opportunity to collaborate with the amazing Nucleus team in our quest for develop neurotherapeutics for hypoxic injuries! This is a BIG step forward! #TeamScience is the future, and the future is here for us! chemh.stanford.edu/news/sarafan...
chemh.stanford.edu
Sarafan ChEM-H awards six $50,000 grants through inaugural Nucleus Seed Grant Program
The grants will allow Stanford researchers to collaborate with the Nucleus, a collection of labs designed to supercharge basic and translational science at Sarafan ChEM-H.
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 11/03/2025
I wonder what happened to the alcohol sales in the past 2 months…😂
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 06/03/2025
Our current situation is an effective demonstration of what happens when you put MONEY-and POWER-focused businessman in charge of caring for PEOPLE and their personal well-being.
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Reposted by Anca M. Hrastinski, MD (former Pasca)
Denis Jabaudon @djabaudon.bsky.social · 05/03/2025
Open positions in human developmental neuroscience, check it out!
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 13/02/2025
Viruses and the body made a pretty “thoughtful “compromise when they decided on an incubation period before symptoms… by the time the second person in the house gets sick, the first one is recovered and ready to take care of the rest 🙄
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 12/02/2025
I now added another brain to my office decor 🥰
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 16/01/2025
I wish all my work days could be as productive as today 🤩
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 13/01/2025
Dear 🦋team, point me to protocols for performing RBC transfusions in neonatal rat or mouse models. Thank you, thank you!
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 10/01/2025
This is, by far, the most interesting and informative research study I have seen…so much to unfold here for translational purposes, drug development etc! Amazing work research team and Cell team! www.cell.com/cell/fulltex...
cell.com
Atlas of the plasma proteome in health and disease in 53,026 adults
A large-scale proteomics study involving 53,026 individuals maps 2,920 plasma proteins to 406 prevalent diseases, 660 incident diseases, and 986 health-related traits, identifying promising biomarkers for disease discrimination and potential therapeutic targets and paving the way for precision medicine.
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 08/01/2025
👏🏻👏🏻👏🏻
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Reposted by Anca M. Hrastinski, MD (former Pasca)
Anshul Kundaje @anshulkundaje.bsky.social · 07/01/2025
Very excited to announce that the single cell/nuc. RNA/ATAC/multi-ome resource from ENCODE4 is now officially public. This includes raw data, processed data, annotations and pseudobulk products. Covers many human & mouse tissues. 1/ www.encodeproject.org/single-cell/...
encodeproject.org
Single cell – ENCODEHomo sapiens clickable body map
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 07/01/2025
Stanford Pediatrics Pulmonary Division is looking for a physician-scientist for a faculty position - all ranks. Consider joining us! facultypositions.stanford.edu/en-us/job/49...
facultypositions.stanford.edu
Stanford | Faculty Positions: Details - Pediatric Pulmonary Faculty
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 03/01/2025
Let it snow @ Lake Tahoe ☃️🗻❄️
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 28/12/2024
In the self checkout line at the store. Machine: transaction approved Me (loudly): Thank you! Have a good day! My brain 1 sec later: Well, that was embarrassing. You need more sleep.
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 26/12/2024
Merry Christmas from the Neo ICU …the place where tears of pure happiness or deep heartbreak can be shed at the same time just a few feet away, and can bring families together in the strongest way possible. I will always be in awe of the strength, resilience, love and selflessness of NICU families.
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 23/12/2024
Little kids in their holidays pajamas and crocs, sipping hot chocolate at Starbucks at 8 am, might be one of my favorite things during this time of the year 🥰
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 21/12/2024
NICU has been super busy all week, we are all running around like crazy…but…today someone gifted us little preemie hats and I got to give them to babies in rounds 😍…oh… I also decided it was boba day for the team! Everyone is simply amazing! #StanfordNeoProud @stanfordmedicine.bsky.social
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 13/12/2024
We made gingerbread houses for our Lab Holiday Party this year 😍. Lots of fun, much needed relaxation…and a bit of competition 😂
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 11/12/2024
Always a pleasure to collaborate with Julien Sage's lab @stanfordmedicine.bsky.social, and very proud of my postdoc Jongbin Choi for leading the #organoid part of this work THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle. www.biorxiv.org/content/10.1...
biorxiv.org
THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
A growing number of therapies are being developed to target the cell cycle machinery for the treatment of cancer and other human diseases. Consequently, a greater understanding of the factors regulati...
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 09/12/2024
Our lab meeting today…🔥! 😍😍😍 I cannot say it enough! I love my team!
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 06/12/2024
Chicago drivers are awesome! They actually use their blinkers when they change lanes! Take note, California drivers, take note!
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 04/12/2024
We ended up in the ED with my 2 yr dog thinking she is having a stroke. She was positive for THC. The vet said it is very common for dogs to end in the ED with overdoses after walks in public places. 🤦🏼‍♀️🤦🏼‍♀️🤦🏼‍♀️ Not something I thought I would ever have to worry about. www.knudsensnews.com/post/experts...
knudsensnews.com
Experts are Warning Dog Owners to Be On the Lookout for Fentanyl Overdoses
Miami, FL - When police officer Chad Blaze was out walking the jet black 14-month-old Havanese he had recently adopted from a local animal shelter, the last thing on his mind was the possibility of a ...
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Reposted by Anca M. Hrastinski, MD (former Pasca)
Giorgia Quadrato @giorgiaquadrato.bsky.social · 03/12/2024
We're excited to share our comprehensive protocol for generating human cerebellar #organoids, addressing the many requests we've received from the scientific community! Congratulations to Alex Atamian, @marcellabirtele.bsky.social, and Negar Hosseini! rdcu.be/d13Zu @natureportfolio.bsky.social
rdcu.be
Generation and long-term culture of human cerebellar organoids from pluripotent stem cells
Nature Protocols - Generation and long-term culture of a human pluripotent stem cell-derived human cerebellar organoid model, which successfully replicates the cellular diversity of the fetal...
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 02/12/2024
My brain coral fossil 😍
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 02/12/2024
I am not sure I am ready for this transition
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 30/11/2024
Nature’s art 😍
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Reposted by Anca M. Hrastinski, MD (former Pasca)
Craig Brown @craigedbrown.bsky.social · 28/11/2024
Congrats to the team! Here we directly image and quantify cerebral #angiogenesis and pruning in vivo. Found interesting regional differences and dependence on #notch signalling. Where you look does matter! www.cell.com/cell-reports...
cell.com
Angiogenesis in the mature mouse cortex is governed in a regional- and Notch1-dependent manner
The angiogenic capacity of the mature healthy brain and its underlying mechanisms are unclear. Raudales et al. show that rates of cerebral angiogenesis follow regional gradients and are regulated by e...
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 27/11/2024
About 10 years into Neonatal ICU practice, and I am still in awe of how small our smallest babies are. Adult CPR mask versus smallest Neonatal one 🤯 for comparison.
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 26/11/2024
Desperately needed a day off…decided to let my evolutionary conserved foraging instinct take over today…you will find me at the mall.
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 22/11/2024
A scientific miracle is happening in this #organoid 🤩. Can’t wait to share the details once confirmed and validated! #FluorescenceFriday
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 18/11/2024
Looking for hindbrain specific genes…any leads? Thank you, thank you #neuroteam
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 17/11/2024
I wish I could transfer my posts from X…
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Anca M. Hrastinski, MD (former Pasca) @braintherapies.bsky.social · 15/11/2024
Looking for neuro starter packs to join!
media.tenor.com
a baby with a green shirt on says help
ALT: a baby with a green shirt on says help
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