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Sarah Gorey

@sarahgorey.bsky.social
66 followers 50 following 6 posts

👩🏻‍⚕️ Geriatric Medicine Fellow 🇮🇪 in 🇺🇸, 🧠Stroke Research & PhD candidate UCD Dublin, 💻MSc NUIG Galway, YSPR committee European Stroke Organisation 🇪🇺

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Reposted by Sarah Gorey
NEJM.org @nejm.org · 03/10/2025
For a student with strep throat and an unconfirmed penicillin allergy, would you prescribe a nonpenicillin antibiotic or give penicillin under doctor supervision? Read the case vignette and essays on both treatment options and cast your vote: nej.md/48eHjm9 #MedSky #MedEd
An illustration of a patient with strep throat, a box of penicillin, and the patient's medical record
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Reposted by Sarah Gorey
CORE IM @coreimpodcast.bsky.social · 01/10/2025
1/ 🚨 NEW #BeyondJournalClub w/ @NEJMGroup: The Bolland study Question: Does infrequent zoledronate therapy in patients without osteoporosis prevent fractures? Answer: ⤵️ www.coreimpodcast.com/2025/10/01/b...
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Sarah Gorey @sarahgorey.bsky.social · 04/09/2025
Well done @cpkotanidis.bsky.social ! Also check out our manuscript in @annalsofim.bsky.social url.us.m.mimecastprotect.com/s/kNYpCDkAO2...
url.us.m.mimecastprotect.com
ACP Journals
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Reposted by Sarah Gorey
Peer Review Congress #PRC11 Coming 2029! @peerreviewcongress.bsky.social · 04/09/2025
2.2.1 In an RCT comparing 'uselessly elongated' vs shorter #PeerReview of @neuripsconf.bsky.social 2022 submissions, the longer reviews received higher quality scores, suggesting a length bias among reviewers, w implications for #LLM-generated reviews journals.plos.org/pl... @scsatcmu.bsky.social
Evaluators exhibited a significant elongated review bias (P < .001). Elongated reviews received a mean score of
4.29 vs. 3.73 for original reviews. Each individual criterion also showed length bias (P < .05).
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Reposted by Sarah Gorey
Peer Review Congress #PRC11 Coming 2029! @peerreviewcongress.bsky.social · 04/09/2025
In the med literature, statements like “to our knowledge [TOK], this is the FIRST...” often replace a proper systematic search. Among 4488 PMC articles in 6 leading medical journals published 2020-2024, TOK prevalence was 21.7%, w @PLOSMedicine highest (48.4%) and @NEJM lowest (1.3%) #CornellVet
In 2 journals, Journal of Small Animal Practice (JSAP) and Journal of Exotic Pet Medicine (JEPM), an intervention to advise authors against use of these phrases and in favor of a scoping search of the literature was implemented in 2020, w decreases from 37.4% to 7.6% after the intervention.
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Reposted by Sarah Gorey
Chris Kotanidis @cpkotanidis.bsky.social · 31/07/2025
The win ratio method is gaining traction in #RCTs. Is it just a trend or a smarter way to look at composite hierarchical outcomes? We break it down in our latest Stats, STAT!📊 in NEJM Evidence. youtube.com/watch?v=jKtF... #stats @nejm.org @sarahgorey.bsky.social @chardin.bsky.social @ai.nejm.org
youtube.com
How Win Ratios Work | NEJM Evidence
YouTube video by NEJM Group
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Reposted by Sarah Gorey
Blue Planet Society @blueplanetsociety.bsky.social · 02/06/2025
Irish whale watching business closes after 25 years. 🐳 “There are only a few whales left - the water is overfished.” The owner was previously a commercial fisher but gave up when fish stocks crashed. “It wasn’t something I wanted to be a part of.” 🎣❌ www.irishtimes.com/ireland/2025...
irishtimes.com
‘It’s an empty, lifeless sea’: Whales leave Cork waters, putting watchers out of business
Stocks of sprat have crashed, forcing whales away, says businessman whose livelihood has been ruined
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Sarah Gorey @sarahgorey.bsky.social · 29/05/2025
🐈🐕📈📉👩‍💻🛋️
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 19/05/2025
In the BATURA trial, as-needed albuterol–budesonide resulted in a lower risk of severe asthma exacerbation than as-needed albuterol among participants with disease that was uncontrolled despite treatment for mild asthma. Full trial results: nej.md/43uVpwK #ATS2025 @atscommunity.bsky.social
A graph showing the first severe asthma exacerbation, assessed in a time-to-event analysis, in the on-treatment efficacy population (primary end point)
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 21/05/2025
BRIDGE-TNK trial: Among 550 patients with stroke due to large-vessel occlusion who had presented within 4.5 hours after onset, 90-day functional outcomes were better with intravenous tenecteplase before thrombectomy than with thrombectomy alone. nej.md/3GTVKAk #ESOC2025 @esostroke.bsky.social
A figure showing the distribution of scores on the modified Rankin scale at 90 days in the intention-to-treat population
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Sarah Gorey @sarahgorey.bsky.social · 06/05/2025
Really enjoying @cpkotanidis.bsky.social’s fascinating presentation on his interesting work at @brighamandwomens.bsky.social on identifying risk markers of CVD in patients with IMIDs 🤩👏👏👏
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 02/05/2025
For a woman with device-detected atrial fibrillation, would you initiate anticoagulant therapy or recommend continuation of antiplatelet therapy? Read the case vignette and essays on both treatment options and cast your vote: nej.md/4lQzxTA #MedSky #CardioSky #Afib
CLINICAL DECISIONS 
Anticoagulation or Antiplatelet Therapy for Device-Detected Atrial Fibrillation 

An illustration of a smartwatch monitoring ECG and two bottles, one containing an anticoagulant, and the other containing aspirin
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 27/04/2025
Both clonal hematopoiesis of indeterminate potential (CHIP) and cancer are more common with age. When they coexist in the same patient, CHIP cells may migrate to the tumor and have an adverse effect on overall survival. Full study results: nej.md/3EnzMVu #MedSky #Hematology
A schematic representation of clonal hematopoiesis of indeterminate potential (CHIP) and tumor-infiltrating clonal hematopoiesis (TI-CH) in a patient with lung cancer.
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 22/04/2025
Our partnership with @glaucomflecken.bsky.social continues as he summarizes new research into fracture prevention with infrequent zoledronate in women 50 to 60 years of age. Access the article for free: nej.md/DrG15 #MedSky
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 22/04/2025
A 56-year-old man was transferred to a burn center for management of pavement burns on his feet that had occurred during a heat wave. Read the full case details: nej.md/3Rh2XfR @uwsph.bsky.social #MedSky #ClimateChange
Images in Clinical Medicine 
Climate Change 
Pavement Burns 

Photo of burns on the patient's feet
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Chris Kotanidis @cpkotanidis.bsky.social · 22/04/2025
New research alert: Our latest report highlights a significant reduction in coronary #inflammation and residual inflammatory risk as captured by #CCTA imaging using CaRi-Heart AI in women with #BreastCancer 2 years post-RT #AI #CardioOncology #CardioEd #EHJ @escardio.bsky.social
academic.oup.com
Coronary inflammation and cardiovascular risk in breast cancer after radiotherapy
Radiotherapy (RT) is known to reduce the rate of disease recurrence following breast-conserving surgery in patients with breast cancer, but also entails ir
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Reposted by Sarah Gorey
CORE IM @coreimpodcast.bsky.social · 16/04/2025
1/ 🚨 NEW #BeyondJournalClub w/ @NEJMGroup: PURPOSE Trials Both PURPOSE 1 & 2 used a new long acting medication: Lenacapavir! Let’s learn what we can takeaway from these trials ⤵️ 🖥️: coreimpodcast.com/2025/04/16/a-r…
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Shreya P. Trivedi MD, MHPE @shreyatrivedimd.bsky.social · 02/04/2025
An outstanding episode - learned a ton 🥂
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NEJM.org @nejm.org · 29/03/2025
Editorial: Cancer-Associated Venous Thromboembolism — Beyond 6 Months nej.md/4iB6wcA
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Chris Kotanidis @cpkotanidis.bsky.social · 26/03/2025
Ever wondered how interim analyses work in #RCTs? 📊 Check out our Stats, STAT! video at NEJM Evidence: @nejm.org @ai.nejm.org @sarahgorey.bsky.social evidence.nejm.org/doi/full/10.... #MedStats #ClinicalTrials
evidence.nejm.org
How Interim Analyses Work
This Stats, STAT! animated video explores interim analyses in clinical trials. During these evaluations of the data, researchers may assess safety, efficacy, and verify sample size assumptions, but...
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 18/03/2025
What is the impact of microplastics on human health? The latest episode of Beyond Journal Club, a collaboration between @coreimpodcast.bsky.social and NEJM Group, takes a deep dive into the APAChE study on microplastics and cardiovascular disease. 🎧 Listen here: nej.md/4igpJQy #MedSky
An illustration of the APAChE study results
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 14/03/2025
The SCALE Kids trial, summarized here by NEJM Editorial Fellow Harleen Marwah, MD, assessed the efficacy and safety of liraglutide, as compared with placebo, as an adjunct treatment to lifestyle interventions, for the treatment of obesity in children 6 to 12 years of age. Full trial: nej.md/3MBP1uc
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Sarah Gorey @sarahgorey.bsky.social · 05/03/2025
A great listen from the coreIM team on potential health effects of microplastics and a nuanced discussion on causality and limitations of observational studies ❤️👏🐥
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Irish Doctors for the Environment @irishdocsenv.bsky.social · 25/02/2025
A truly beautiful piece by Dr Lisa McNamee (@lisadangermcnamee.bsky.social)! Everyone should read this!
medicalindependent.ie
Turning despair into action  - Medical Independent
In January, climate action advocate and Dundalk GP Dr Seán Owens was seriously injured while cycling home from work...
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The Lancet @thelancet.com · 25/02/2025
"By staying true to its mission and embracing necessary reforms, PEPFAR can...continue to be a beacon of hope in the fight against HIV/AIDS." Comment—PEPFAR under review: what's at stake for PEPFAR's future tinyurl.com/28ahdmv8 #MedSky
tinyurl.com
PEPFAR under review: what's at stake for PEPFAR's future
The US President's Emergency Plan for AIDS Relief (PEPFAR) faces a pivotal moment, confronting one of its most challenging periods since its launch in 2003. The new policy priorities of the administra...
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 25/02/2025
How much training do you need to do to run a 5K? 🏃 The NEJM Evidence team aims to find out in this Stats, STAT! animated video on linear regression. Watch the full video: youtu.be/qUfVrYKetfA  #MedSky #ScienceSky #Statistics
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JAMA @jama.com · 18/02/2025
"Without research to point toward a healthier country, there will be poorer national health and less capacity to do what people do...on either end of the political spectrum." Read the Editorial by JAMA Health Forum EIC Sandro Galea and JAMA EIC @kbibbinsdomingo.bsky.social. ja.ma/4b6Z2LJ #MedSky
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NEJM.org @nejm.org · 12/02/2025
Perspective by Eleanor R. Menzin, MD: With U.S. politics threatening to erase the gains of science, reduce access to vaccines, and undermine their vast public health benefit, what is a conscientious pediatrician to do? Read the full Perspective: nej.md/4iZNHQW
Square image with a purple background and a quote from a Perspective article by Eleanor R. Menzin, M.D., that reads "Some will ask, “Can you recommend a good pediatrician who does not believe in vaccines?” No, I say, no more than I can recommend a good physicist who does not believe in gravity." At the bottom of the image is "NEJM" next to the logo for the New England Journal of Medicine.
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 12/02/2025
A 29yo man with well-controlled HIV infection presented with a 1-week history of a painful, whitish discoloration on his tongue. Smooth, pink, guttate macules were present on the tongue within a white coating. Full case from @aidshealthcare.bsky.social : nej.md/4jNuAdw #MedSky #IDSky
Images in Clinical Medicine
Plaques en Prairie Fauchée Tongue Lesions in Secondary Syphilis

Photo of the patient's tongue
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The Lancet @thelancet.com · 07/02/2025
“...to care is an act not of weakness, but of strength.” The Lancet response: bit.ly/4jRb5Av
A Lancet Editorial: “American chaos: standing up for health and medicine”
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NEJM.org @nejm.org · 05/02/2025
Editorial: Medium- and Distal-Vessel Occlusion — The Limit of Thrombectomy? nej.md/40Hu9bP
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NEJM.org @nejm.org · 05/02/2025
In the DISTAL trial involving 543 patients with stroke due to occlusion of medium or distal vessels, endovascular treatment within 24 hours after the onset of symptoms was not effective in improving functional outcome at 90 days. nej.md/4jYWV0z #ISC25 | @ahascience.bsky.social
nej.md
Endovascular Treatment for Stroke Due to Occlusion of Medium or Distal Vessels | NEJM
Endovascular treatment (EVT) of stroke with large-vessel occlusion is known to be safe and effective. The effect of EVT for occlusion of medium or distal vessels is unclear. We randomly assigned pa...
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 05/02/2025
In the ESCAPE-MeVO trial involving patients with ischemic stroke due to medium-vessel occlusion, thrombectomy within 12 hours did not lead to a better functional outcome and lower mortality at 90 days than usual care. Full trial results: nej.md/40LTUaL #ISC25 | @ahascience.bsky.social
nej.md
Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion | NEJM
Whether the large effect size of endovascular thrombectomy (EVT) for stroke due to large-vessel occlusion applies to stroke due to medium-vessel occlusion is unclear. In a multicenter, prospective,...
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The Irish Times @irishtimes.com · 04/02/2025
Epilepsy: ‘It’s like having the sword of Damocles above your head’
irishtimes.com
Epilepsy: ‘It’s like having the sword of Damocles above your head’
Former international cricketer Emma Beamish on living with the anxiety of never knowing when it might strike again, and her decision not to have children
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Reposted by Sarah Gorey
NEJM.org @nejm.org · 02/01/2025
An 84-year-old man with benign prostatic hyperplasia who had been admitted to the hospital with acute kidney injury due to obstructive uropathy was noted to have gray skin. The skin changes had been present for 5 years. 1/3 #MedSky
Image Challenge
What is the diagnosis?

Left: Photo of the patient’s face.
Right: Photo of the patient’s hands (top) and skin biopsy (bottom).
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NEJM.org @nejm.org · 03/01/2025
From March through October 2024, a total of 46 human cases of highly pathogenic avian influenza A(H5N1) virus infections were identified in the United States, with 20 linked to poultry exposure and 25 to dairy cow exposure. Read the full article: nej.md/3VU4R8I  #MedSky #IDSky
nej.md
Highly Pathogenic Avian Influenza A(H5N1) Virus Infections in Humans | NEJM
Highly pathogenic avian influenza A(H5N1) viruses have caused widespread infections in dairy cows and poultry in the United States, with sporadic human cases. We describe characteristics of human A...
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CORE IM @coreimpodcast.bsky.social · 11/12/2024
1/ 🚨 NEW #BeyondJournalClub with @NEJMGroup: REVISE Trial Do PPIs reduce the risk of clinically important upper GI bleeding? ⤵️ 🖥️: coreimpodcast.com/2024/12/11/str… Sponsor: Freed AI
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Sarah Gorey @sarahgorey.bsky.social · 10/12/2024
@nejm.org is seeking submissions for images highlighting the health impact of climate change to be featured during Earth Month 2025. Info at nejm.org/event-info #MedSky #ClimateChange #EnvironmentalHealth
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Ken Milne MD @thesgem.bsky.social · 27/11/2024
This is a reminder that spurious correlations can be observed in observational studies. We should be skeptical of this type of data. Hypothesis generating. Proper RCTs should be performed if possible to conclude causation. www.tylervigen.com/spurious-cor... #MedSky
tylervigen.com
Spurious Correlations
Correlation is not causation: thousands of charts of real data showing actual correlations between ridiculous variables.
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Irish Doctors for the Environment @irishdocsenv.bsky.social · 27/11/2024
Irish people will die in significant numbers due to rising temperatures. Irish people will die in significant numbers due to rising temperatures, HSE specialist claims, yet #ClimateChange remains a peripheral issue of the #GE24.
irishtimes.com
Irish people will die in significant numbers due to rising temperatures, HSE specialist claims
Healthcare is at climate frontline, notably in emergency departments and at primary care level, conference hears
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Sarah Gorey @sarahgorey.bsky.social · 22/11/2024
The New England Journal of Medicine is inviting submissions for Images in Clinical Medicine on the theme of health impacts of climate. Deadline is 1 Jan! See nejm.org for details #climate #healthimpactofclimatechange #climateandhealth #climatecrisis
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