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Yale Cancer Center

@yalecancer.bsky.social
750 followers 154 following 1.1K posts

Yale Cancer Center is a collaboration between renowned cancer researchers and physicians at Yale University and Smilow Cancer Hospital.

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Yale Cancer Center @yalecancer.bsky.social · 6h
Beatrice Katsnelson shared analysis of 2,186 patients with #NSCLC, noting KEAP1 & SMARCA4 tumor mutations predicted development of bone mets. Findings suggest molecular profiling could identify high-risk pts and increase surveillance strategies. #ASTRO26 @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 6h
Dr. Victor Lee shared that patients with #prostatecancer & TP53 mutations had higher pathologic lymph node involvement. Noting incorporating TP53 mutational status into risk stratification models could improve patient selection for elective nodal irradiation. #ASTRO26 @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 6h
Dr. Mary-Kate Lawlor presented new data #ASTRO26 showing in 81 patients with stage III uterine serous carcinoma, #EBRT significantly improved pelvic control + OS vs vaginal brachytherapy alone (4-year OS 87% vs. 55%) without increased toxicity. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 6h
Dr. Victor Lee presents an analysis of patients with stage I–III #breastcancer through MSK-CHORD #ASTRO26 showing TP53 mutations were associated with development of brain mets, suggesting TP53 mutational status may enhance risk stratification. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 6h
Congratulations to Dr. Christopher Rodman, recipient of @nanets.bsky.social Clinical Investigator Scholarship (NCIS) Award for: "Radiomics, Deep Learning, and Digital Pathology to Identify Biomarkers of Response & Resistance to Capecitabine/Temozolomide in Advanced Pancreatic Neuroendocrine Tumors.”
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Yale Cancer Center @yalecancer.bsky.social · 21h
Dr. Mary Kate Lawlor presented a Quick Pitch presentation earlier today at #ASTRO26 on "Morbidity of Pelvic Recurrence in Stage 3 Uterine Serous Carcinoma." amportal.astro.org/sessions/qp-29… @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
Dr. Victor Lee will present during a Scientific Symposium this afternoon #ASTRO26 on "TP53 Mutations in Primary Breast Tumors Predict Brain Metastases: Insights from the MSK CHORD Cohort." amportal.astro.org/sessions/ss-40… @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
Dr. Ignaty Leshchiner and colleagues analyzed #cfDNA blood samples from 12,000+ patients with metastatic #breastcancer & found serial cfDNA testing can detect newly-emerging resistance mutations before clinical progression. medicine.yale.edu/cancer/publi... @yalecbb.bsky.social
medicine.yale.edu
Blood-Based Circulating DNA Testing Maps Metastatic Breast Cancer
This study shows that liquid biopsy—blood-based tumor DNA testing—reveals widespread treatment-resistance mutations across 12,827 patients with metastatic
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
Stop by Exhibit Hall A this afternoon #ASTRO26 as we have five poster presentations on the schedule, featuring: Yue Tang; Daniel Liu; Beatrice Katsnelson; and Victor Lee. @yaleschoolofmed.bsky.social @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
New data from Dr. Erica Shen #ASTRO2026 finds in adults undergoing allogeneic stem cell transplant for ALL or AML, TBI with lung shielding yielded a 13.4% rate of severe pulmonary toxicity. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
Dr. James Ninia presents the HyDEF phase I trial #ASTRO26. The protocol treats two halves of the same tumor with radiobiologically equivalent but different fractionated doses. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
Proud to have Drs. Henry Park; Shari Damast; Melissa Young; and Suzanne Evans moderating education sessions during Monday's program at #ASTRO2026, representing the depth of expertise and academic leadership in our department. Thank you and congratulations to all four! @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
New data presented by Maneeth Ellendula @yaleschoolofmed.bsky.social #ASTRO2026 identifies SMARCA4 mutations as a predictor of brain mets in early-stage non-small lung cancer #NSCLC. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 29/09/2026
Maneeth Ellendula @yaleschoolofmed.bsky.social presented a Quick Pitch presentation today #ASTRO26: "Association of SMARCA4 Primary Tumor Mutations with Brain Metastases in Initially Non-Metastatic Non-Small Cell Lung Cancer." amportal.astro.org/sessions/qp-12… @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
This afternoon in Room 256, Dr. Suzanne Evans presents "Safety and Quality Considerations in Clinical Care: Lessons Learned from RO-ILS" as part of an #ASTRO26 Education Session.amportal.astro.org/sessions/edu-2… @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
At #ASTRO26, we are proud to welcome so many Yale attendees, including our current residents and the alumni of our Radiation Oncology Residency Program, and advancing the field of radiation oncology. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
At #ASTRO26 Dr. Cary Gross @carygross.bsky.social presented on Comparative Effectiveness and Value in Cancer Care, exploring how we measure and communicate the value of #radiationoncology and #cancercare. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
Dr. Shari Damast presented "Advanced #EndometrialCancer Case Discussion - The Significance of Molecular Status" in an #ASTRO26 Education Session this morning. amportal.astro.org/sessions/edu-2… @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
Today at #ASTRO26, we have two AM and two PM poster presentations scheduled in Exhibit Hall A. Please stop by and support your colleagues and their research: Drs. Dae Han; Anvi Sud; James Ninia; and Erica Shen. @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
De. Henry Park at #ASTRO26: How should we interpret randomized Phase II trials in radiation oncology? Dr. Park reviewed the potential impact of phase II clinical trials, while reviewing the need for scrutiny of results. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
Dr. James Ninia shares a case series of early radium therapy from the #YNHH archives, the birth of modern #brachytherapy, at #ASTRO26. @astro-org.bsky.social @oncoalert.bsky.social amportal.astro.org/sessions/pqa-0…
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
Dr. Shari Bodofsky shares research #ASTRO26 showing women <45 with rectal cancer who undergo pelvic radiation face early menopause. Early counseling on fertility preservation and hormone therapy improve outcomes. @astro-org.bsky.social @oncoalert.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 28/09/2026
This morning in Room 256 at #ASTRO26, @carygross.bsky.social presents "Comparative Effectiveness and Value in Cancer Care" as part of an Education Session. amportal.astro.org/sessions/edu-1… @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 27/09/2026
New research from Dr. Giorgio Caturegli at #ASTRO26 compares neoadjuvant FOLFOX vs. CROSS chemoradiation for esophageal adenocarcinoma. FOLFOX was associated with higher CRR, higher 5-year recurrence-free and overall survival in unadjusted analyses. @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 27/09/2026
Today at 4:45pm in Rm 210 #ASTRO26, Dr. Henry Park presents "Promising or Premature? Making Sense of Randomized Phase 2 Trials in #RadiationOncology." ➡️amportal.astro.org/sessions/pro-1… @astro-org.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 27/09/2026
As #ASTRO26 begins, we start with six poster presentations today at 3pm featuring Drs. Shari Bodofsky; Giorgio Caturgli; Alexis Gayne; Ella Zhang; James Ninia; and Colin McNamara. @ASTRO_org
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Yale Cancer Center @yalecancer.bsky.social · 27/09/2026
Tonight at 7:30pm on #YaleCancerAnswers, Dr. Jeremy Kortmansky shares insight into the changes in the management of GI cancers and the impact of #immunotherapy and combination therapies. 🎧Listen live #wnpr 💻Listen later #ApplePodcasts; #Spotify; #YouTube
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Yale Cancer Center @yalecancer.bsky.social · 25/09/2026
Thank you, @anirbanmaitra.bsky.social for your excellent presentation and visit to New Haven! Watch Dr. Maitra's full talk, "Mediators of Restraint in Early Pancreatic Neoplasia," on our YouTube channel: youtu.be/j_VYvB0R3_Y?.... @pamelakunzmd.bsky.social
youtu.be
Mediators of Restraint in Early Pancreatic Neoplasia with Dr. Anirban Maitra
YouTube video by Yale Cancer Center
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Yale Cancer Center @yalecancer.bsky.social · 23/09/2026
Smilow Cancer Hospital’s Cellular Therapy Program is proud to announce that it ranks 3rd in the nation in patients treated with #Breyanzi. We’re proud of this achievement and remain committed to providing exceptional care to patients. @yale-hematology.bsky.social @cibmtr.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 22/09/2026
Today at 12pm, we are pleased to welcome Dr. Anirban Maitra @anirbanmaitra.bsky.social for our #GrandRounds and Koenigsberg Lecture! Dr. Maitra will present "Mediators of Restraint in Early Pancreatic Neoplasia." Join us in Smilow Auditorium or online via Zoom: bit.ly/4gWZv7G.
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Yale Cancer Center @yalecancer.bsky.social · 22/09/2026
Dr. Cece Calhoun joined the #HemeTalks #Podcast to discuss one of the most vulnerable moments in #sicklecell care: the transition from pediatric to adult management. open.spotify.com/episode/53Be... @yale-hematology.bsky.social @ash.hematology.org
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Yale Cancer Center @yalecancer.bsky.social · 21/09/2026
We’re grateful for the @yale.edu College Class of 1961 #CancerEndowment, which has grown to more than $3.5 million, awarding over $900,000 in research grants to young scientists at @yalecancer.bsky.social. medicine.yale.edu/news-article...
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Yale Cancer Center @yalecancer.bsky.social · 21/09/2026
Yesterday’s #SmilowSalute was an emotional and exciting stop on @ctfride.bsky.social 💙 A huge thank you to our amazing riders, volunteers, and donors for your enthusiasm and support of patient care and research at Smilow Cancer Hospital and Yale Cancer Center. #CTFRide
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Yale Cancer Center @yalecancer.bsky.social · 18/09/2026
#Osimertinib appears to ⬇️ the elevated brain metastasis risk historically associated with two common subtypes of EGFR mutations, supporting osimertinib's role as a preferred first-line treatment for EGFR-mutant #NSCLC. medicine.yale.edu/cancer/publi... @oncoalert.bsky.social
medicine.yale.edu
Osimertinib and Brain Metastasis Risk in Lung Cancer
This study shows that osimertinib reduces brain metastasis risk differences seen between two common EGFR lung cancer mutation subtypes.
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Yale Cancer Center @yalecancer.bsky.social · 16/09/2026
Congratulations Dr. Jeremy Jacox, recipient of a Seed Grant from the Hirshberg Foundation. The grant program provides early funding to support basic scientists and clinicians for improving diagnosis and developing new treatment modalities for #pancreaticcancer. pancreatic.org/research/see...
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Yale Cancer Center @yalecancer.bsky.social · 16/09/2026
Elaine Yang @yaleschoolofmed.bsky.social presented research during a poster session yesterday at #WCLC in Seoul: "CT-Detected Residual Thymic Tissue Predicts Pathologic Complete Response to Neoadjuvant Therapy in Locally Advanced #NSCLC." cattendee.abstractsonline.com/meeting/2148...
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Yale Cancer Center @yalecancer.bsky.social · 16/09/2026
Dr. VIctor Lee presented a mini-oral session yesterday at #WCLC in Seoul: "ATRX Mutations Are Enriched in Female #NSCLC and Associated With Higher Tumor Mutational Burden." cattendee.abstractsonline.com/meeting/2148... @iaslc.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 15/09/2026
Today at 12pm marks the return of our #GrandRounds! Drs. Maximilian Stahl and Jan Bewersdorf present on "New Directions in #AML and #Myelofibrosis." Join us in Smilow Auditorium or online via Zoom: bit.ly/4A7szkr @yale-hematology.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 15/09/2026
Dr. Patrick Oh presented his research during a poster session yesterday at #WCLC in Seoul: "Poor Survival and Increased Nodal Metastasis in SMARCA4-Mutant Lung Adenocarcinoma in a Multi-Cohort Analysis." cattendee.abstractsonline.com/meeting/2148... @iaslc.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 15/09/2026
In new #pancreascancer research, @muzumdarlab.bsky.social et al. find that the pre-existing molecular state of a #PDAC cell exerts greater influence over how a #KRAS mutation behaves than the identity of the mutation itself. medicine.yale.edu/cancer/publi... @molecularomics.bsky.social
medicine.yale.edu
How Cell State Shapes KRAS Mutation Effects in Pancreatic Cancer
This study shows that in pancreatic cancer cells, a cell's baseline state—not which KRAS mutation it carries—drives its molecular behavior.
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Yale Cancer Center @yalecancer.bsky.social · 14/09/2026
Dr. Henry Park, an accomplished violinist, returned to the stage at #WCLC to perform alongside Dr. Andreas Rimner at the Journal of Thoracic Oncology #JTO 20th Anniversary Reception! @iaslc.bsky.social @yale.edu
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Yale Cancer Center @yalecancer.bsky.social · 14/09/2026
Dr. Anne Chiang presented at #WCLC in Seoul as a discussant for the exciting primary results of the Phase 3 ARTEMIS-008 trial, debated optimal use of therapeutic agents in #SCLC, and saw a friendly face! @iaslc.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 14/09/2026
Dr. Henry Park presents a research poster at #WCLC in Seoul tonight on "Androgen Receptor Mutations in #NSCLC are Enriched in Females and Predict Better Immunotherapy Response." cattendee.abstractsonline.com/meeting/21487/… @iaslc.bsky.social
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Yale Cancer Center @yalecancer.bsky.social · 13/09/2026
Early onset cancer is the topic tonight on #YaleCancerAnswers, and guests Drs. Nancy Borstelmann and Veda Giri join to talk about diagnosis and family history, and the unique challenges young patients face. 🎧Listen live #WNPR ▶️Available on #ApplePodcasts, #Spotify, #YouTube
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Yale Cancer Center @yalecancer.bsky.social · 11/09/2026
A new study from @jeffreytownsend.bsky.social shows how ranking mutations by cancer effect size, not frequency alone, can surface rare, potentially high-impact variants overlooked by standard approaches. medicine.yale.edu/cancer/publi... @plosone.org @yalesph.bsky.social
medicine.yale.edu
Driver Mutations in Chinese Liver Cancer Ranked
This study identifies which mutations most strongly drive hepatocellular carcinoma—liver cancer—in Chinese patients by measuring each mutation's selective
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Reposted by Yale Cancer Center
Jeffrey Townsend @jeffreytownsend.bsky.social · 09/09/2026
In liver cancer, the most frequent mutations aren’t always the most important. 🧪 Estimating the growth and proliferation advantage in tumor evolution, we identified rare, high-effect candidates that frequency-based analyses can miss. ♋ @yalecancer.bsky.social: medicine.yale.edu/cancer/publi...
medicine.yale.edu
Driver Mutations in Chinese Liver Cancer Ranked
This study identifies which mutations most strongly drive hepatocellular carcinoma—liver cancer—in Chinese patients by measuring each mutation's selective
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Yale Cancer Center @yalecancer.bsky.social · 10/09/2026
Congratulations to Dr. Nikolai Podolsev @yale-hematology.bsky.social, whose leadership of a #clinicaltrial at Smilow Cancer Hospital resulted in FDA approval of #Besremi ( #ropeginterferon ) for treatment of #essentialthrombocythemia (ET). thelancet.com/journals/lan...
thelancet.com
Ropeginterferon alfa-2b-njft treatment in essential thrombocythemia across different driver mutations: results from a North American, single-arm, multicentre study (EXCEED-ET)
Ropeg showed efficacy and substantial molecular responses with good overall tolerability across a broad ET population.
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Yale Cancer Center @yalecancer.bsky.social · 09/09/2026
Dr. Aram Bidikian and Yale colleagues share a case report in Leukemia & Lymphoma @tandfonline.bsky.social on the reversal of systemic mastocytosis-induced liver #cirrhosis with #avapritinib treatment. tandfonline.com/doi/full/10.... @yale-hematology.bsky.social @yalepathology.bsky.social
tandfonline.com
Reversal of systemic mastocytosis-induced liver cirrhosis with avapritinib treatment: case report
Published in Leukemia & Lymphoma (Ahead of Print, 2026)
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Yale Cancer Center @yalecancer.bsky.social · 06/09/2026
Dr. Gabriel Cartagena joins #YaleCancerAnswers for an important discussion on #mentalhealth and #cancer -how it affects the patient and their family, caregivers, and managing depression, anxiety, + trauma. 🎧Listen live #WNPR tonight at 7:30pm ▶️Listen later #ApplePodcasts, #Spotify, #YouTube
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Yale Cancer Center @yalecancer.bsky.social · 04/09/2026
Dr. Samir Zaidi received an @theaacr.bsky.social Trailblazer Cancer Research Grant earlier this year + in the latest #CancerDiscovery @aacrjournals.bsky.social he shares commentary on his research project, Decoding Lineage Plasticity as the Engine of Therapy Escape." aacrjournals.org/cancerdiscov...
aacrjournals.org
Insights on Future Directions in Cancer Research from the AACR Trailblazer Cancer Research Grant Awardees
The American Association for Cancer Research (AACR) Trailblazer Cancer Research Grant Program is a historic initiative intended to provide talented investigators with the resources to support innovati...
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