iiinova — where your digital self keeps evolving

Reposted by Dina Schuster

Basavraj Khanppnavar @basurajsk.bsky.social · 22/04/2026

How do cells integrate multiple signals into precise responses? Our study uncovers neuronal calcium sensor proteins as new regulators of adenylyl cyclase 8, linking GPCR-cAMP-Ca²⁺ signaling. @rflorea.bsky.social @dina-sch.bsky.social @psi.ch @eth-dbiol.bsky.social www.biorxiv.org/content/10.6...

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Reposted by Dina Schuster

Pedro Beltrao @pedrobeltrao.bsky.social · 04/03/2026

We have started a project trying to predic the interactions/structures of all yeast protein pairs using an AlphaFold pooling approach. We are making the current dataset open and we welcome collaborations. www.evocellnet.com/2026/03/mapp...

evocellnet.com

Mapping the yeast atructural interactome with AlphaFold3: an open call for collaboration

We are excited to announce the early-stage release of our S. cerevisiae structural interactome mapping project. Using AlphaFold3 (AF3), w...

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Dina Schuster @dina-sch.bsky.social · 11/02/2026

Congratulations!!! Well deserved 🥳

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Reposted by Dina Schuster

Keri Backus @keribackus.bsky.social · 06/02/2026

Excited to share our new paper and lipid- and protein-directed photocatalytic labeling method (POCA) just out in @natchembio.nature.com. tinyurl.com/2kcxuvvv. Big congrats to first author Andrew Becker and the whole team for launching our lab into the wild world of singlet oxygen interactomics.

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Reposted by Dina Schuster

Picotti Lab @picottilab.bsky.social · 13/01/2026

We’re delighted to report a global structural proteome analysis within living cells! doi.org/10.1038/s443... #proteomics #structuralproteomics #massspectrometry #structuralbiology #ethz @imsb-eth.bsky.social

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Reposted by Dina Schuster

Sarafan ChEM-H @stanford-chemh.bsky.social · 15/01/2026

#ICYMI The Chemoproteomics Group at the Nucleus, led by @dina-sch.bsky.social, uses mass spec-based techniques to study proteins & their molecular interactions. The group supports Stanford researchers throughout a project, from design consultation to data analysis.

youtube.com

Chemoproteomics Group at the Nucleus, Sarafan ChEM-H

The Chemoproteomics Group at the Nucleus, Sarafan ChEM-H, led by Dr. Dina Schuster, focuses on a wide range of mass spectrometry-based techniques to study proteins and their molecular interactions.…

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Reposted by Dina Schuster

Alice Ting @aliceyting.bsky.social · 08/01/2026

Can we design mutations that bias proteins towards desired conformational states? Today in @science.org, we introduce Conformational Biasing (CB), a simple and scalable computational method that uses contrastive scoring by inverse folding models to identify conformation-biasing mutations.

science.org

Computational design of conformation-biasing mutations to alter protein functions

Conformational biasing (CB) is a rapid and streamlined computational method that uses contrastive scoring by inverse folding models to predict protein variants biased toward desired conformational sta...

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Reposted by Dina Schuster

Ruth Huttenhain @rhuttenhain.bsky.social · 02/10/2025

My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology: postdocs.stanford.edu/prospective/... #TeamMassSpec #Proteomics #GPCR #Postdoc

postdocs.stanford.edu

Open Postdoctoral position, faculty mentor Ruth Huttenhain | Office of Postdoctoral Affairs

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Reposted by Dina Schuster

Polly Fordyce @pollyfordyce.bsky.social · 29/09/2025

Come and join us @stanford-chemh.bsky.social! It's an amazing place to do interdisciplinary science & I'm so grateful to be in this community. Faculty applications due 10/15/2025 -- please share widely. Interested but not sure you're ready to apply this year? DM me & I'm happy to provide advice :)

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Reposted by Dina Schuster

Sarafan ChEM-H @stanford-chemh.bsky.social · 24/09/2025

Sarafan ChEM-H awards four $25K seed grants to fund collaborations w/ the new chemoproteomics group, led by @dina-sch.bsky.social at the Nucleus, a collection of labs that leverage scientific experts& advanced instrumentation to facilitate discoveries @stanford.edu chemh.stanford.edu/news/sarafan...

chemh.stanford.edu

Sarafan ChEM-H awards four $25K seed grants to fund collaborations with the new chemoproteomics group at the Nucleus

The grants will give researchers access to advanced instrumentation and technical guidance for a variety of specialized proteomics techniques.

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Dina Schuster @dina-sch.bsky.social · 29/07/2025

Come work with us at the Nucleus @stanford-chemh.bsky.social! Happy to help you with proteome analyses, identifying your drug targets, understanding drug mechanisms, and much more 🔎🕵🏻

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Reposted by Dina Schuster

Andrea Sinz 🧪 @sinzandrea.bsky.social · 25/06/2025

‼️ Job alert 🚨: I have an open 3-year postdoc position in my lab to develop novel crosslinking mass spectrometry workflows. 🧪🧪 So if you want to do cool stuff in protein MS, please apply ! ⬇️ Please RT www.verwaltung.uni-halle.de/dezern3/Auss... #Academicsky #Chemsky #teammassspec

verwaltung.uni-halle.de

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Dina Schuster @dina-sch.bsky.social · 23/05/2025

We heat up the ADC at the inlet of the mass spectrometer, separate the isoforms within the instrument and analyze each isoform in one run. This is one step away from the commonly used methods that probe only the bulk stability and gives direct insights into each specific drug-load species. 3/3

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Dina Schuster @dina-sch.bsky.social · 23/05/2025

ADCs are heterogeneous drug products. They are antibodies linked with varying amounts of drugs. Their stabilities are often assessed at the bulk level, completely ignoring the fact that the individual drug linked species have different properties! That’s where vT-ESI-MS can help. 2/3

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Dina Schuster @dina-sch.bsky.social · 23/05/2025

Ever wondered how stable your ADCs are and how their stability is influenced by their drug-load? Variable-temperature electrospray ionization can help with that! Jan Fiala’s and my postdoc work in the lab of @hecklab.bsky.social was just published! 🥳🥳🥳 pubs.acs.org/doi/10.1021/... 1/3

pubs.acs.org

Antibody–Drug Conjugate Stability Probed by Variable-Temperature Electrospray Ionization Mass Spectrometry

Antibody–drug conjugates (ADCs) are effective anticancer biotherapeutics, often referred to as “magic bullets” due to their high specificity and cytotoxicity. This unique drug class consists of cytoto...

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Dina Schuster @dina-sch.bsky.social · 22/05/2025

Some sections have been claimed already and I can only include a limited number of authors. Deadline for the submission is July 1st, so we have to move fast. Please feel free to share! #TeamMassSpec #MassSpectrometry #Proteomics #MembraneProteins 3/3

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Dina Schuster @dina-sch.bsky.social · 22/05/2025

We will be writing the manuscript on GitHub, using Manubot. Please check out the repository for more information: github.com/dschust-r/re... Feel free to DM me or post an Issue, if you’d like to contribute. Please tell me what section you would like to contribute to. 2/3

github.com

GitHub - dschust-r/review_ms_mem_prot: Community review on "Advances in Mass Spectrometry for Membrane Protein Pharmacology"

Community review on "Advances in Mass Spectrometry for Membrane Protein Pharmacology" - dschust-r/review_ms_mem_prot

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Dina Schuster @dina-sch.bsky.social · 22/05/2025

Call for membrane protein mass spectrometry scientists! 🥼 I have the opportunity to write a short review on “Advances in Mass Spectrometry for Membrane Protein Pharmacology“, and I am looking for fellow membrane protein mass spec enthusiasts to contribute. 1/3

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Reposted by Dina Schuster

Ying Ge @yingge2121.bsky.social · 14/05/2025

Please join us for proteoform Thurs this Thurs. Our former student, David Roberts will be presenting. David is a very talented young scientist and a great speaker. Please register using the link 👇 please help share @proteoforms.bsky.social @joelooucla.bsky.social ❤️

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Dina Schuster @dina-sch.bsky.social · 09/05/2025

Great presentation on #FragPipe and its capabilities. Definitely learned a lot! Thank you @nesvilab.bsky.social for virtually stopping by to give a talk during our #proteomics users group meeting here @stanford.edu and for answering all our questions 😊 #massspec #teammassspec #StanfordProteomics

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Dina Schuster @dina-sch.bsky.social · 04/05/2025

I have a timsTOF HT right now that I am very happy with! The Ascend is on my desk, the timsTOF in the lab 😊

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Dina Schuster @dina-sch.bsky.social · 03/05/2025

That one is nice too! I wonder if they will have any new sets at ASMS this year 👀

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Dina Schuster @dina-sch.bsky.social · 02/05/2025

Wow, the set DID come with other options, I completely missed that. Just thought they had - for some weird reason - included multiples of the same label.

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Dina Schuster @dina-sch.bsky.social · 02/05/2025

That’s a good point! I just checked and mine is the MultiOmics edition. It came with some replacement labels (total of 3 labels), need to check them when I am at home. Will update you when I get home and am able to check 😊

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Dina Schuster @dina-sch.bsky.social · 01/05/2025

Is is an Ascend 😊 Never saw a Lumos set but I imagine they would be almost impossible to distinguish

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Dina Schuster @dina-sch.bsky.social · 30/04/2025

Do you have this one? It‘s not really an issue but just wondering. Looks much better with the proper source build 😊

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Dina Schuster @dina-sch.bsky.social · 30/04/2025

I was missing 2 parts at the top, or I thought I was - do you also have a little gap at the top between the gray and black panels? I had used the parts from the source to make that edge even at the top but that looked bad. “Fixed“ the source after taking the picture because it started to bother me 😅

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Reposted by Dina Schuster

Joost Snijder @joostsnijder.bsky.social · 29/04/2025

Excited to announce our revamped PhD-level BioMS course this September: Advanced Proteomics for Drug Discovery and Biotherapeutics Great line-up of instructors and topics, registration is open: www.hecklab.com/advanced-pro...

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Dina Schuster @dina-sch.bsky.social · 29/04/2025

I love it! 🥰 Still need to get my hands on a Stellar 👀

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Dina Schuster @dina-sch.bsky.social · 29/04/2025

Here’s the fully assembled Ascend 😉

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Dina Schuster @dina-sch.bsky.social · 29/04/2025

Tribrid is correct! Unfortunately, the mass specs are hollow on the inside. The Vanquish LC set is pretty cool, you can open the different compartments.

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Dina Schuster @dina-sch.bsky.social · 29/04/2025

Lego mass specs will never get boring 🥰 Any guesses on which one I am assembling? #massspec #teammassspec

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Reposted by Dina Schuster

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 25/04/2025

What a great month of science and inspiration as hosts of sabbatical visitor @hecklab.bsky.social, looking forward to our next encounters!

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Reposted by Dina Schuster

Olga Vitek @olgavitek.bsky.social · 15/04/2025

A few more spots are still open for some of the in-person programs at May Institute on Computation and Statistics for Mass Spectrometry and Proteomics on April 28 – May 11, 2025 on the campus of Northeastern University in Boston MA computationalproteomics.khoury.northeastern.edu

computationalproteomics.khoury.northeastern.edu

May Institute – Computation and statistics for mass spectrometry and proteomics

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Reposted by Dina Schuster

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 11/04/2025

SCAM ALERT. This is a fake conference that ripped off my and other people’s names to trick people into registering. There is no such conference that I or the others shown were invited or agreed to. We are working to try to get this fraud taken down from the web. chemsymposia.com

chemsymposia.com

Join Chemsymposia 2026: Research & Innovation | ChemSymposia 2026

Join us at Chemsymposia 2026 to discover groundbreaking research in physics applications. Connect with experts, engage in insightful discussions, and explore our venue, registration details, and speak...

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Dina Schuster @dina-sch.bsky.social · 07/04/2025

Exploring the great California outdoors at the #Sunol regional wilderness preserve this weekend: lush green hills, beautiful wildflowers, lots of squirrels, and even a bobcat (!) - I’m a fan.

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Dina Schuster @dina-sch.bsky.social · 24/03/2025

Love Caltrain’s Swiss trains, almost feels like I am still in Switzerland🇨🇭

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Reposted by Dina Schuster

Erin Baker @erinbakerims.bsky.social · 07/03/2025

I had the opportunity to give my perspective to The Analytical Scientist about recent events. With this article, I hope to give a voice to others who may not have the ability to speak out. #StandUpForScience theanalyticalscientist.com/business-edu...

theanalyticalscientist.com

A Bleak Future?

Recent layoffs and funding cuts have not only crippled morale among scientists, they’ve also set an alarming precedent for the future of science

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Reposted by Dina Schuster

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 05/03/2025

It is important at this pivotal moment to @standupforscience.bsky.social. Looking forward to sharing my thoughts on why this should be a national priority at tomorrow’s rally in SF:

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Dina Schuster @dina-sch.bsky.social · 04/03/2025

It’s a challenging time (not only but also) for science in the US right now. We have to do what we can to maintain the high level of scientific progress and that includes my new position, I think.

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Dina Schuster @dina-sch.bsky.social · 04/03/2025

Thank you, Alex 😊 Hope you’re also doing well!

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Dina Schuster @dina-sch.bsky.social · 04/03/2025

Thank you! Looking forward to a great time together @stanford-chemh.bsky.social 😊

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Dina Schuster @dina-sch.bsky.social · 04/03/2025

Very excited to announce that I have moved across the pond to start my new position as Assistant Director for Chemoproteomics @ the Nucleus @stanford-chemh.bsky.social. This position allows me to do what I love: fun science, collaborations & teaching everyone about the wonders of #massspectrometry 🥳

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