West Nile virus (WNV) is one of the leading causes of arthropod-transmitted encephalitis in the world, yet its effects on neurons, the principal target of WNV in the brain, remain poorly defined. Here...

Cellular signaling is inherently organized in space and time, requiring coordinated control of protein localization, molecular interactions, and enzym…

High-throughput data-independent acquisition (DIA) workflows paired with short chromatographic separations are increasingly adopted for systems biology and clinical proteomics. However, narrower peak ...

Targeted proteomics technologies, and specially data-independent acquisition techniques, have revolutionized the landscape of proteomic research in the last decade offering researchers unprecedented …

The HUPO Early Career Researcher (ECR) Committee was founded in 2015 and has since actively and tirelessly promoted the transmission of HUPO ideals to the

The HUPO Early Career Researcher Committee is organizing three Mentoring Sessions during the HUPO 2022 World Congress in Toronto, ON, Canada (November 9-13, 2025). The topic of one of the three mentor...

Researchers are organizing protests and making their voices heard as Trump officials slash funding and lay off federal scientists.

Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background la...

The Huttenhain Lab at Stanford University studies cellular signaling networks to uncover how cells decode extracellular cues into dynamic physiologic responses.