Reposted by Diego Sainz de la MazaBloomington Drosophila Stock Center @bdsc.bsky.social · 15/10/202640 years ago today, the BDSC made its 1st shipment. To celebrate, Trudy Kaufman, who packed the 1st shipment, boxed up the same kinds of flies for John Roote at Cambridge, who placed the 1st order. Watch for pics of the arrival next week. We’ve shipped 4,882,378 vials total. That’s a lot of flies! 515553
Reposted by Diego Sainz de la MazaJess Miers 🦝 @jmiers230.bsky.social · 13/09/2026I did a somewhat deep dive into the recent OpenAI and Anthropic "hacks" for an upcoming interview. IMO, the AI companies are better off running with the "rogue AI" story because the real story is actually pretty embarrassing. Like making your Wi-Fi password "wifi" embarrassing. 🧵 341836794
Reposted by Diego Sainz de la MazaPatricia Fernández de Lis @pflis.bsky.social · 09/09/2026Ojo a esto que va a traer cola. Como dice Terence Tao, y ¿ahora, qué? Si un rumor puede desplegar miles de agentes con millones de dólares por parte de una IA, ¿qué incentivo le queda a nadie para compartir ideas prometedoras antes de tenerlas cerradas? elpais.com/ciencia/2026...elpais.comEl anuncio de OpenAI de que ha resuelto uno de los mayores enigmas matemáticos de la historia desata acusaciones de plagioUn matemático acusa a la tecnológica de usar investigaciones y de “presiones” para excluir a otro investigador de Anthropic 0197
Reposted by Diego Sainz de la MazaAltmetric @altmetric.com · 08/09/2026Update: The academic flight from Twitter is now complete and appears permanent. April 2023, after the pandemic research surge, we recorded 2,234,307 posts sharing research on Twitter. As of April this year, "X" had 896,741 posts about research. That's a 60% drop in traffic. 9318136
Reposted by Diego Sainz de la MazaAlexander Shakeel Bates @asbates.bsky.social · 04/09/2026And now this new beast - the full male fly central nervous system connectome - is out in print! www.cell.com/cell/fulltex... A phenomenal resource, @ukri.org @hhmijanelia.bsky.social, @cellpress.bsky.socialcell.comSexual dimorphism in the complete Drosophila male central nervous system connectomeThe Drosophila whole male central nervous system connectome enables end-to-end analysis of sensorimotor circuits. Comparison with existing female datasets shows that brain-wide wiring differences betw... 063
Reposted by Diego Sainz de la Mazathe Node @the-node.bsky.social · 26/08/2026Revisiting metabolic fundamentals In this post on the Node, Liliana Piñeros & @diegosainzdelamaza.bsky.social report on the Workshop, ‘Revisiting metabolic fundamentals,’ aimed at reframing metabolism as an information-processing and signalling system. thenode.biologists.com/revisiting-m...thenode.biologists.comRevisiting metabolic fundamentals - the NodeIn this post, Liliana Piñeros and Diego Sainz de la Maza report on the Workshop, 'Revisiting metabolic fundamentals'. 062
Reposted by Diego Sainz de la MazaNature @nature.com · 30/07/2026Nature research paper: Intestinal stem cells count self-renewal divisions to switch multipotency go.nature.com/45uYCwngo.nature.comIntestinal stem cells count self-renewal divisions to switch multipotency - NatureIn Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing an enteroendocrine mother cell every ninth division. 0268
Reposted by Diego Sainz de la MazaMarco MILAN LAB @milanlab.bsky.social · 20/08/2026Treat biological databases as infrastructure, not projects www.nature.com/articles/d41...nature.comTreat biological databases as infrastructure, not projectsLetter to the Editor 013
Reposted by Diego Sainz de la MazaCSICdivulga @csicdivulga.bsky.social · 29/06/2026🟡El CSIC inicia la conmemoración de los 120 años de la JAE con el acto ‘Ciencia, represión y memoria del CSIC’, en el que se presentará el proyecto ‘La represión del CSIC sobre la JAE (1939-1950)’. Inscripciones ➡️ tinyurl.com/2mcxafe3 @csic.es @cchscsic.bsky.social @cienciagob.bsky.social 055
Reposted by Diego Sainz de la MazaScience Magazine @science.org · 14/07/2026The Spanish National Research Council, established under Francisco Franco’s dictatorship, has published the stories of some 500 researchers and support staff purged after the civil war. Learn more: scim.ag/3Rq5EiJ 0348
Reposted by Diego Sainz de la MazaNSF–DOE Rubin Observatory @rubinobservatory.org · 30/06/2026The moment we've all been waiting for is finally here… On June 29, 2026, NSF–DOE Rubin Observatory officially began the Legacy Survey of Space and Time (LSST)! 🔭🧪☄️🌌 🔗: rubinobservatory.org/news/action-... 3294138
Reposted by Diego Sainz de la MazaCivio @civio.es · 30/06/2026¿Para quién son las viviendas protegidas de alquiler en España? En muchos casos, necesitas cobrar más de 2.000€ al mes para acceder a una vivienda social. No es una exageración. En las casas del Plan Vive, de la Comunidad de Madrid, las condiciones de acceso no son para la mayoría social. ⬇️🧵civio.esAlquiler de vivienda protegida: para rentas superiores a la media y a precio de mercadoVarias comunidades, con Madrid a la cabeza, marcan ingresos mínimos para arrendar vivienda protegida que en algunos casos llegan a superar los 2.000 euros mensuales y máximos de hasta 90.000 euros. 1918
Reposted by Diego Sainz de la MazaJames Briscoe @jamesbriscoe.bsky.social · 18/06/2026As Editor of @dev-journal.bsky.social I get asked "What are you doing about your impact factor?" In our new editorial we say: Ask not what Dev can do for the impact factor. Ask what you can do for Dev's IF The IF is about how we all cite, review & assess each other's work doi.org/10.1242/dev....doi.orgThe elephant in the room: impact factorSummary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ... 06633
Reposted by Diego Sainz de la MazaAmoyel lab @amoyellab.bsky.social · 11/06/2026Fantastic news for the lab! We've just been awarded a Wellcome Discovery award and will be recruiting at postdoc and research assistant level shortly. We're excited by this project that aims to understand how metabolism influences male germline development. Please forward to any interested people! 63610
Reposted by Diego Sainz de la MazaThe EMBO Journal @embojournal.org · 11/06/2026Somatic cells compartmentalise their carbohydrate metabolism to sustain germ cell survival @diegosainzdelamaza.bsky.social, Marc Amoyel et al link.springer.com/article/10.1...link.springer.comSomatic cells compartmentalise their carbohydrate metabolism to sustain germ cell survival - The EMBO JournalTo ensure success in reproduction, organisms dedicate substantial resources to supporting the germline. In testes, somatic gonadal cells form a barrier that isolates germ cells from circulating nutrie... 075
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 11/06/2026My latest work is out in @embojournal.org, and it well deserves a 🧵!!!👇 For the first time in vivo, we show that somatic gonadal cells sustain the developing germline by producing lactate through glycolysis and shuttling it directly to germ cells to keep them alive link.springer.com/article/10.1...link.springer.comSomatic cells compartmentalise their carbohydrate metabolism to sustain germ cell survival - The EMBO JournalTo ensure success in reproduction, organisms dedicate substantial resources to supporting the germline. In testes, somatic gonadal cells form a barrier that isolates germ cells from circulating nutrie... 392
Reposted by Diego Sainz de la MazaTominaga K. (tomiken) @pacyc184.bsky.social · 28/05/2026PlasmidGPT: A generative framework for plasmid analysis and generation | Science Advances www.science.org/doi/full/10.1126/sc…science.orgPlasmidGPT: A generative framework for plasmid analysis and generationA generative framework predicts plasmid features and enables controlled generation of functional DNA sequences. 0112
Reposted by Diego Sainz de la MazaScience News @sciencenews.bsky.social · 28/05/2026On cloudy days, immune cells serve as the homing pigeon’s internal compass. www.sciencenews.org/article/pigeon-…sciencenews.orgHoming pigeons may use a surprising navigation mechanismHow animals navigate by Earth's magnetic field is hotly debated. New research in pigeons points to iron-laden liver immune cells as the compass. 022
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 02/05/2026It was amazing to be part of this. Lots of new ideas to test in the lab! 010
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 15/04/2026Antonio García-Bellido (1936-2025): journals.biologists.com/dev/article/...journals.biologists.comAntonio García-Bellido (1936-2025)When asking Artificial Intelligence (Google Gemini) about Antonio, it responds: ‘It's not every day you talk about a man who literally helped map out how a single cell knows how to become a complex wi... 000
Reposted by Diego Sainz de la MazaScience News @sciencenews.bsky.social · 25/03/2026Dogs in Europe had been domesticated from wild wolves by at least 14,200 years ago, two new genetic studies suggest. www.sciencenews.org/article/oldest-…sciencenews.orgWhen were dogs domesticated? The oldest known dog DNA offers cluesTwo new studies suggest that genetically stable dogs were living among humans in Europe by about 14,000 years ago. 061
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 26/03/2026I'm a Luddite, Why Aren't Youyoutube.comPYCON UK 2025: I m a Luddite Why Aren't You, CJ ShearwoodYouTube video by PYCON UK 000
Reposted by Diego Sainz de la MazaWaggoner Lab @labwaggoner.bsky.social · 18/02/2026Turning on the ‘for you’ feed on X shifted political opinions, but turning it off did not @nature.com www.nature.com/articles/d41... www.nature.com/articles/s41...nature.comTurning on the ‘for you’ feed on X shifted political opinions, but turning it off did notUsers started and continued following right-wing accounts even after switching back to a chronological feed. 001
Reposted by Diego Sainz de la MazaNature Metabolism @natmetabolism.nature.com · 08/12/2025bit.lyFat sensory cues in early life program central response to food and obesityNature Metabolism, Published online: 01 December 2025; doi:10.1038/s42255-025-01405-8Non-nutritive sensory components of high-fat diet, such as bacon flavour, are sufficient to impair metabolic health in offspring in mice. 022
Reposted by Diego Sainz de la MazaNature Metabolism @natmetabolism.nature.com · 10/12/2025bit.lyNeuronal fatty acid oxidation fuels memory after intensive learning in DrosophilaNature Metabolism, Published online: 10 December 2025; doi:10.1038/s42255-025-01416-5Neurons are shown to use fatty acid β-oxidation as a fuel source for memory formation upon intensive learning in Drosophila, challenging the view that neurons are unable to use fatty acids for energy production. 041
Reposted by Diego Sainz de la MazaMetabolism in Development and Physiology, Virtual Seminar Series @devmetphys.bsky.social · 08/01/2026We’re back with the Metabolism in Development & Physiology online seminar series 🎉 Thu 15 Jan 2025, 16:00 CET Speakers: Heidi Lempradl (Professor, VAI) Diego Sainz de la Maza (PostDoc, UCL) 045
Reposted by Diego Sainz de la MazaEL PAÍS México @elpaismexico.bsky.social · 04/01/2026El pastelero que patentó una molécula contra el cáncer que se ha vendido por 7.000 millones de euros dozz.es/tgwbd7dozz.esEl pastelero que patentó una molécula contra el cáncer que se ha vendido por 7.000 millones de eurosEl biólogo Eduard Batlle, criado en la pastelería de sus padres, es uno de los seis inventores del petosemtamab, un revolucionario tratamiento experimental contra los tumores 001
Reposted by Diego Sainz de la MazaSEBD @sebioldev.bsky.social · 18/12/2025Now @thenode.bsky.social #SEBD Honours Antonio García-Bellido thenode.biologists.com/sebd-honours...thenode.biologists.comSEBD Honours Antonio García-Bellido - the NodeA Pioneer in Developmental Biology On the past 10th of November, Antonio García-Bellido passed away. Widely regarded as the father of the Spanish school 032
Reposted by Diego Sainz de la MazaEl Salto @elsaltodiario.com · 07/12/2025El artista vasco Koque Martínez descansa eternamente, bajo el mismo sol y a la sombra de los mismos cipreses, junto a Karl Marx. elsaltodiario.comKoque Martínez, el artista vasco que está enterrado junto a Karl MarxEl azar se empeñó en que dos hombres que jamás coincidieron en vida descansen eternamente bajo el mismo sol, a la sombra de los mismos cipreses y, sobre todo, unidos por la lealtad a una idea que los llevó lejos de sus casas. 0149
Reposted by Diego Sainz de la MazaScience Magazine @science.org · 20/11/2025This parasitic ant tricks workers into killing their own queen. Learn more: scim.ag/43FNdcR 16111
Reposted by Diego Sainz de la MazaCentro de Biología Molecular Severo Ochoa @cbm-csic-uam.bsky.social · 19/11/2025Este viernes a las 19:00h, la Residencia de Estudiantes y el CBM organizamos una sesión de homenaje a Antonio García-Bellido, con la participación de sus discípulos, amigos y colegas. Estáis todos invitados a venir. 033
Reposted by Diego Sainz de la MazaNature @nature.com · 20/10/2025Obituary: John Gurdon (1933-2025) Biologist who made cloning possible go.nature.com/3WicRAego.nature.comJohn Gurdon obituary: Biologist who made cloning possibleHe showed that specialized cells retain the genes to form an organism. 05016
Reposted by Diego Sainz de la MazaDevelopment @dev-journal.bsky.social · 09/10/2025An Interview with Azim Surani Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia: journals.biologists.com/dev/article/... 01712
Reposted by Diego Sainz de la MazaFlyBase @flybase.bsky.social · 03/10/2025There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase... We express enormous gratitude to the people, labs, groups, and foundations who have already helped us. #FlyBase #Drosophila 14540
Reposted by Diego Sainz de la MazaFlyBase @flybase.bsky.social · 16/09/2025The FlyBase situation has made the national news www.nbcnews.com/science/scie...nbcnews.comTrump's Harvard cuts threaten a giant in biomedical research: A database about the tiny fruit flyThis spring, the Trump administration rescinded a grant that maintained FlyBase, a pillar of global basic research, as part of its broader $2.2 billion funding cuts at Harvard. 02827
Reposted by Diego Sainz de la Mazathe Node @the-node.bsky.social · 11/09/2025Congratulations to the winners of our image competition with the @mblscience.bsky.social Embryology course. The winner of the Editor’s choice is an image of a anole lizard eye, acquired by Arthur Boutillon @campaslab.bsky.social. thenode.biologists.com/results-from... #devbio 🔬🎉 14011
Reposted by Diego Sainz de la MazaFlyBase @flybase.bsky.social · 15/08/2025FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...wiki.flybase.orgFlyBase:Contribute to FlyBase - FlyBase Wiki 3130159
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 25/07/2025New preprint from the lab! Check it out, we show how somatic gonadal cells ensure that carbohydrate metabolism is wired to support the developing germline! Ah, and we rename a gene! 010
Reposted by Diego Sainz de la MazaAmoyel lab @amoyellab.bsky.social · 25/07/2025🆕🧪‼️ New lab preprint! We study how germ cells (the cells that give rise to gametes, in this case sperm) are supported by somatic (non-germ) cells of the gonad. This matters for our understanding of reproduction - without germ cell development, animals are sterile. www.biorxiv.org/content/10.1...biorxiv.orgSomatic cells compartmentalise their metabolism to sustain germ cell survivalTo ensure success in reproduction, organisms dedicate substantial resources to supporting the germline. In testes, somatic gonadal cells form a barrier that isolates germ cells from circulating nutrie... 12612
Reposted by Diego Sainz de la MazaAnthony Ricciardi @ecoinvasions.bsky.social · 23/05/2025"Thinking time —the time needed to concentrate without interruptions has always been central to scholarly work. It is essential to designing experiments, compiling data, assessing results, reviewing literature and, of course, writing. Yet, [it] is often undervalued." www.nature.com/articles/d41... 4339132
Reposted by Diego Sainz de la MazaAndreas Prokop @poppi62.bsky.social · 10/04/2025If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social 092102
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 20/02/2025Acabar un día de trabajo echando un ratico para hablar de lo divino, de lo humano y de los testículos de la mosca de la fruta fue una gozada. Gracias @raticosdeciencia.bsky.social 010
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 06/02/2025nature.comMitochondria as you’ve never seen them — January’s best science imagesThe month’s sharpest science shots, selected by Nature’s photo team. 010
Reposted by Diego Sainz de la MazaArmando Iannucci @aiannucci.bsky.social · 29/01/2025you.38degrees.org.uk/petitions/sa...you.38degrees.org.ukSave The Prince Charles CinemaThe future of the iconic Prince Charles Cinema in London’s West End is under serious threat! We are beyond disappointed that our landlords, Zedwell LSQ Ltd and their ultimate parent company Criterion... 423960
Reposted by Diego Sainz de la MazaNature @nature.com · 13/01/2025A decade in, expansion microscopy is unlocking insights across biology and medicine go.nature.com/4adlNgggo.nature.com‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the massesA decade in, expansion microscopy is unlocking insights across biology and medicine. 18519
Reposted by Diego Sainz de la MazaGavin Woodruff @weirdworms.bsky.social · 12/12/2024Spread of yellow-bill-color alleles favored by selection in the long-tailed finch hybrid system www.cell.com/current-biol...cell.comSpread of yellow-bill-color alleles favored by selection in the long-tailed finch hybrid systemCarotenoid color ornaments play important roles in social signaling and species recognition. Hooper et al. show that bill-color variation in long-tailed finches is associated with genes controlling the metabolism of red pigments from yellow dietary precursors. Selection favoring yellow alleles is causing the trait to introgress between subspecies. 021
Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 11/01/2025Repurposing of a gill gene regulatory program for outer ear evolutionnature.comRepurposing of a gill gene regulatory program for outer ear evolution - NatureNature - Repurposing of a gill gene regulatory program for outer ear evolution 000
Reposted by Diego Sainz de la MazaManuel Ansede @manuelansede.bsky.social · 30/12/2024Un experimento en un laboratorio español ha recreado la Tierra primitiva y han surgido protocélulas, un paso previo a los seres vivos. “No hay un soplo divino” en el origen de la vida, afirma el geólogo Juan Manuel García Ruiz elpais.com/ciencia/2024...elpais.comUn experimento recrea el mundo sin vida y surgen protocélulas, un paso previo a los seres vivos: “No hay un soplo divino”Los investigadores, de un laboratorio español, observan por primera vez la aparición de compartimentos junto a los ingredientes básicos de los organismos 23919
Reposted by Diego Sainz de la MazaFlyBase @flybase.bsky.social · 23/12/2024New #GeneGroups subset: Metabolic Pathways! These manually curated reports aim to facilitate metabolic research in Drosophila by providing high-quality gene lists and visual representations of fly metabolic pathways, integrated with the other rich data in FlyBase. 1136
Reposted by Diego Sainz de la MazaThe Interactive Fly @interactivefly.bsky.social · 23/12/2024Kaur, R., McGarry, A., Shropshire, J. D., Leigh, B. A., Bordenstein, S. R. (2024). Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality. Science, 383(6687):1111-1117 www.science.org/doi/10.1126/...science.orgProphage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethalityWolbachia prophage manipulates sperm noncoding RNA and DNA vital for chromatin integrity and offers potential leads for vector control. 011