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Diego Sainz de la Maza

@diegosainzdelamaza.bsky.social
154 followers 456 following 20 posts

Postdoc at the Amoyel Lab. So far, happy developmental biologist, but I have my days. Studying stem cells and tissue homeostasis in the fly testis. Science is also part of culture

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Reposted by Diego Sainz de la Maza
Bloomington Drosophila Stock Center @bdsc.bsky.social · 15/10/2026
40 years ago today, the BDSC made its 1st shipment. To celebrate, Trudy Kaufman, who packed the 1st shipment, boxed up the same kinds of flies for John Roote at Cambridge, who placed the 1st order. Watch for pics of the arrival next week. We’ve shipped 4,882,378 vials total. That’s a lot of flies!
Trudy Kaufman packing flies to send to John Roote.
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Reposted by Diego Sainz de la Maza
Jess Miers 🦝 @jmiers230.bsky.social · 13/09/2026
I did a somewhat deep dive into the recent OpenAI and Anthropic "hacks" for an upcoming interview. IMO, the AI companies are better off running with the "rogue AI" story because the real story is actually pretty embarrassing. Like making your Wi-Fi password "wifi" embarrassing. 🧵
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Reposted by Diego Sainz de la Maza
Patricia Fernández de Lis @pflis.bsky.social · 09/09/2026
Ojo a esto que va a traer cola. Como dice Terence Tao, y ¿ahora, qué? Si un rumor puede desplegar miles de agentes con millones de dólares por parte de una IA, ¿qué incentivo le queda a nadie para compartir ideas prometedoras antes de tenerlas cerradas? elpais.com/ciencia/2026...
elpais.com
El anuncio de OpenAI de que ha resuelto uno de los mayores enigmas matemáticos de la historia desata acusaciones de plagio
Un matemático acusa a la tecnológica de usar investigaciones y de “presiones” para excluir a otro investigador de Anthropic
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Reposted by Diego Sainz de la Maza
Altmetric @altmetric.com · 08/09/2026
Update: The academic flight from Twitter is now complete and appears permanent. April 2023, after the pandemic research surge, we recorded 2,234,307 posts sharing research on Twitter. As of April this year, "X" had 896,741 posts about research. That's a 60% drop in traffic.
Graph showing cumulative research sharing across platforms, including Twitter - April 2023Graph of April 2026 cumulative research sharing including "X". One third of what it was.
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Reposted by Diego Sainz de la Maza
Alexander Shakeel Bates @asbates.bsky.social · 04/09/2026
And now this new beast - the full male fly central nervous system connectome - is out in print! www.cell.com/cell/fulltex... A phenomenal resource, @ukri.org @hhmijanelia.bsky.social, @cellpress.bsky.social
cell.com
Sexual dimorphism in the complete Drosophila male central nervous system connectome
The Drosophila whole male central nervous system connectome enables end-to-end analysis of sensorimotor circuits. Comparison with existing female datasets shows that brain-wide wiring differences betw...
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Reposted by Diego Sainz de la Maza
the Node @the-node.bsky.social · 26/08/2026
Revisiting metabolic fundamentals In this post on the Node, Liliana Piñeros & @diegosainzdelamaza.bsky.social report on the Workshop, ‘Revisiting metabolic fundamentals,’ aimed at reframing metabolism as an information-processing and signalling system. thenode.biologists.com/revisiting-m...
thenode.biologists.com
Revisiting metabolic fundamentals - the Node
In this post, Liliana Piñeros and Diego Sainz de la Maza report on the Workshop, 'Revisiting metabolic fundamentals'.
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Reposted by Diego Sainz de la Maza
Nature @nature.com · 30/07/2026
Nature research paper: Intestinal stem cells count self-renewal divisions to switch multipotency go.nature.com/45uYCwn
go.nature.com
Intestinal stem cells count self-renewal divisions to switch multipotency - Nature
In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing an enteroendocrine mother cell every ninth division.
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Reposted by Diego Sainz de la Maza
Marco MILAN LAB @milanlab.bsky.social · 20/08/2026
Treat biological databases as infrastructure, not projects www.nature.com/articles/d41...
nature.com
Treat biological databases as infrastructure, not projects
Letter to the Editor
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Reposted by Diego Sainz de la Maza
CSICdivulga @csicdivulga.bsky.social · 29/06/2026
🟡El CSIC inicia la conmemoración de los 120 años de la JAE con el acto ‘Ciencia, represión y memoria del CSIC’, en el que se presentará el proyecto ‘La represión del CSIC sobre la JAE (1939-1950)’. Inscripciones ➡️ tinyurl.com/2mcxafe3 @csic.es @cchscsic.bsky.social @cienciagob.bsky.social
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Reposted by Diego Sainz de la Maza
Science Magazine @science.org · 14/07/2026
The Spanish National Research Council, established under Francisco Franco’s dictatorship, has published the stories of some 500 researchers and support staff purged after the civil war. Learn more: scim.ag/3Rq5EiJ
Spain's largest research organization confronts its dark past.
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Reposted by Diego Sainz de la Maza
NSF–DOE Rubin Observatory @rubinobservatory.org · 30/06/2026
The moment we've all been waiting for is finally here… On June 29, 2026, NSF–DOE Rubin Observatory officially began the Legacy Survey of Space and Time (LSST)! 🔭🧪☄️🌌 🔗: rubinobservatory.org/news/action-...
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Civio @civio.es · 30/06/2026
¿Para quién son las viviendas protegidas de alquiler en España? En muchos casos, necesitas cobrar más de 2.000€ al mes para acceder a una vivienda social. No es una exageración. En las casas del Plan Vive, de la Comunidad de Madrid, las condiciones de acceso no son para la mayoría social. ⬇️🧵
civio.es
Alquiler de vivienda protegida: para rentas superiores a la media y a precio de mercado
Varias comunidades, con Madrid a la cabeza, marcan ingresos mínimos para arrendar vivienda protegida que en algunos casos llegan a superar los 2.000 euros mensuales y máximos de hasta 90.000 euros.
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Reposted by Diego Sainz de la Maza
James Briscoe @jamesbriscoe.bsky.social · 18/06/2026
As Editor of @dev-journal.bsky.social I get asked "What are you doing about your impact factor?" In our new editorial we say: Ask not what Dev can do for the impact factor. Ask what you can do for Dev's IF The IF is about how we all cite, review & assess each other's work doi.org/10.1242/dev....
doi.org
The elephant in the room: impact factor
Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...
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Reposted by Diego Sainz de la Maza
Amoyel lab @amoyellab.bsky.social · 11/06/2026
Fantastic news for the lab! We've just been awarded a Wellcome Discovery award and will be recruiting at postdoc and research assistant level shortly. We're excited by this project that aims to understand how metabolism influences male germline development. Please forward to any interested people!
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The EMBO Journal @embojournal.org · 11/06/2026
Somatic cells compartmentalise their carbohydrate metabolism to sustain germ cell survival @diegosainzdelamaza.bsky.social, Marc Amoyel et al link.springer.com/article/10.1...
link.springer.com
Somatic cells compartmentalise their carbohydrate metabolism to sustain germ cell survival - The EMBO Journal
To ensure success in reproduction, organisms dedicate substantial resources to supporting the germline. In testes, somatic gonadal cells form a barrier that isolates germ cells from circulating nutrie...
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 11/06/2026
My latest work is out in @embojournal.org, and it well deserves a 🧵!!!👇 For the first time in vivo, we show that somatic gonadal cells sustain the developing germline by producing lactate through glycolysis and shuttling it directly to germ cells to keep them alive link.springer.com/article/10.1...
link.springer.com
Somatic cells compartmentalise their carbohydrate metabolism to sustain germ cell survival - The EMBO Journal
To ensure success in reproduction, organisms dedicate substantial resources to supporting the germline. In testes, somatic gonadal cells form a barrier that isolates germ cells from circulating nutrie...
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Reposted by Diego Sainz de la Maza
Tominaga K. (tomiken) @pacyc184.bsky.social · 28/05/2026
PlasmidGPT: A generative framework for plasmid analysis and generation | Science Advances www.science.org/doi/full/10.1126/sc…
science.org
PlasmidGPT: A generative framework for plasmid analysis and generation
A generative framework predicts plasmid features and enables controlled generation of functional DNA sequences.
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Reposted by Diego Sainz de la Maza
Science News @sciencenews.bsky.social · 28/05/2026
On cloudy days, immune cells serve as the homing pigeon’s internal compass. www.sciencenews.org/article/pigeon-…
sciencenews.org
Homing pigeons may use a surprising navigation mechanism
How animals navigate by Earth's magnetic field is hotly debated. New research in pigeons points to iron-laden liver immune cells as the compass.
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 02/05/2026
It was amazing to be part of this. Lots of new ideas to test in the lab!
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 15/04/2026
Antonio García-Bellido (1936-2025): journals.biologists.com/dev/article/...
journals.biologists.com
Antonio García-Bellido (1936-2025)
When asking Artificial Intelligence (Google Gemini) about Antonio, it responds: ‘It's not every day you talk about a man who literally helped map out how a single cell knows how to become a complex wi...
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Reposted by Diego Sainz de la Maza
Science News @sciencenews.bsky.social · 25/03/2026
Dogs in Europe had been domesticated from wild wolves by at least 14,200 years ago, two new genetic studies suggest. www.sciencenews.org/article/oldest-…
sciencenews.org
When were dogs domesticated? The oldest known dog DNA offers clues
Two new studies suggest that genetically stable dogs were living among humans in Europe by about 14,000 years ago.
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 26/03/2026
I'm a Luddite, Why Aren't You
youtube.com
PYCON UK 2025: I m a Luddite Why Aren't You, CJ Shearwood
YouTube video by PYCON UK
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Reposted by Diego Sainz de la Maza
Waggoner Lab @labwaggoner.bsky.social · 18/02/2026
Turning on the ‘for you’ feed on X shifted political opinions, but turning it off did not @nature.com www.nature.com/articles/d41... www.nature.com/articles/s41...
nature.com
Turning on the ‘for you’ feed on X shifted political opinions, but turning it off did not
Users started and continued following right-wing accounts even after switching back to a chronological feed.
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Reposted by Diego Sainz de la Maza
Nature Metabolism @natmetabolism.nature.com · 08/12/2025
bit.ly
Fat sensory cues in early life program central response to food and obesity
Nature Metabolism, Published online: 01 December 2025; doi:10.1038/s42255-025-01405-8Non-nutritive sensory components of high-fat diet, such as bacon flavour, are sufficient to impair metabolic health in offspring in mice.
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Reposted by Diego Sainz de la Maza
Nature Metabolism @natmetabolism.nature.com · 10/12/2025
bit.ly
Neuronal fatty acid oxidation fuels memory after intensive learning in Drosophila
Nature Metabolism, Published online: 10 December 2025; doi:10.1038/s42255-025-01416-5Neurons are shown to use fatty acid β-oxidation as a fuel source for memory formation upon intensive learning in Drosophila, challenging the view that neurons are unable to use fatty acids for energy production.
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Reposted by Diego Sainz de la Maza
Metabolism in Development and Physiology, Virtual Seminar Series @devmetphys.bsky.social · 08/01/2026
We’re back with the Metabolism in Development & Physiology online seminar series 🎉 Thu 15 Jan 2025, 16:00 CET Speakers: Heidi Lempradl (Professor, VAI) Diego Sainz de la Maza (PostDoc, UCL)
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Reposted by Diego Sainz de la Maza
EL PAÍS México @elpaismexico.bsky.social · 04/01/2026
El pastelero que patentó una molécula contra el cáncer que se ha vendido por 7.000 millones de euros dozz.es/tgwbd7
dozz.es
El pastelero que patentó una molécula contra el cáncer que se ha vendido por 7.000 millones de euros
El biólogo Eduard Batlle, criado en la pastelería de sus padres, es uno de los seis inventores del petosemtamab, un revolucionario tratamiento experimental contra los tumores
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Reposted by Diego Sainz de la Maza
SEBD @sebioldev.bsky.social · 18/12/2025
Now @thenode.bsky.social #SEBD Honours Antonio García-Bellido thenode.biologists.com/sebd-honours...
thenode.biologists.com
SEBD Honours Antonio García-Bellido - the Node
A Pioneer in Developmental Biology On the past 10th of November, Antonio García-Bellido passed away. Widely regarded as the father of the Spanish school
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El Salto @elsaltodiario.com · 07/12/2025
El artista vasco Koque Martínez descansa eternamente, bajo el mismo sol y a la sombra de los mismos cipreses, junto a Karl Marx.
elsaltodiario.com
Koque Martínez, el artista vasco que está enterrado junto a Karl Marx
El azar se empeñó en que dos hombres que jamás coincidieron en vida descansen eternamente bajo el mismo sol, a la sombra de los mismos cipreses y, sobre todo, unidos por la lealtad a una idea que los llevó lejos de sus casas.
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Science Magazine @science.org · 20/11/2025
This parasitic ant tricks workers into killing their own queen. Learn more: scim.ag/43FNdcR
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Centro de Biología Molecular Severo Ochoa @cbm-csic-uam.bsky.social · 19/11/2025
Este viernes a las 19:00h, la Residencia de Estudiantes y el CBM organizamos una sesión de homenaje a Antonio García-Bellido, con la participación de sus discípulos, amigos y colegas. Estáis todos invitados a venir.
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Nature @nature.com · 20/10/2025
Obituary: John Gurdon (1933-2025) Biologist who made cloning possible go.nature.com/3WicRAe
go.nature.com
John Gurdon obituary: Biologist who made cloning possible
He showed that specialized cells retain the genes to form an organism.
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Development @dev-journal.bsky.social · 09/10/2025
An Interview with Azim Surani Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia: journals.biologists.com/dev/article/...
Picture of Azim Surani in a dark blue jumper and light blue collared shirt sitting by a microscope.
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FlyBase @flybase.bsky.social · 03/10/2025
There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase... We express enormous gratitude to the people, labs, groups, and foundations who have already helped us. #FlyBase #Drosophila
FlyBase Update – October 2025
The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support:
	•	European labs: Please consider contributing to the Cambridge, U.K. FlyBase group
	•	U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups
	•	Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience.
For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase
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FlyBase @flybase.bsky.social · 16/09/2025
The FlyBase situation has made the national news www.nbcnews.com/science/scie...
nbcnews.com
Trump's Harvard cuts threaten a giant in biomedical research: A database about the tiny fruit fly
This spring, the Trump administration rescinded a grant that maintained FlyBase, a pillar of global basic research, as part of its broader $2.2 billion funding cuts at Harvard.
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the Node @the-node.bsky.social · 11/09/2025
Congratulations to the winners of our image competition with the @mblscience.bsky.social Embryology course. The winner of the Editor’s choice is an image of a anole lizard eye, acquired by Arthur Boutillon @campaslab.bsky.social. thenode.biologists.com/results-from... #devbio 🔬🎉
Development cover: Embryonic eye of an anole lizard stained for nuclei (DAPI, blue) and F-actin (Phalloidin, orange), imaged by spinning disc confocal microscopy and processed using ImageJ. The image was acquired at the 2025 MBL Embryology course by Arthur Boutillon and was the Editor's choice from the Node image competition.
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Reposted by Diego Sainz de la Maza
FlyBase @flybase.bsky.social · 15/08/2025
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
wiki.flybase.org
FlyBase:Contribute to FlyBase - FlyBase Wiki
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 25/07/2025
New preprint from the lab! Check it out, we show how somatic gonadal cells ensure that carbohydrate metabolism is wired to support the developing germline! Ah, and we rename a gene!
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Reposted by Diego Sainz de la Maza
Amoyel lab @amoyellab.bsky.social · 25/07/2025
🆕🧪‼️ New lab preprint! We study how germ cells (the cells that give rise to gametes, in this case sperm) are supported by somatic (non-germ) cells of the gonad. This matters for our understanding of reproduction - without germ cell development, animals are sterile. www.biorxiv.org/content/10.1...
biorxiv.org
Somatic cells compartmentalise their metabolism to sustain germ cell survival
To ensure success in reproduction, organisms dedicate substantial resources to supporting the germline. In testes, somatic gonadal cells form a barrier that isolates germ cells from circulating nutrie...
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Reposted by Diego Sainz de la Maza
Anthony Ricciardi @ecoinvasions.bsky.social · 23/05/2025
"Thinking time —the time needed to concentrate without interruptions has always been central to scholarly work. It is essential to designing experiments, compiling data, assessing results, reviewing literature and, of course, writing. Yet, [it] is often undervalued." www.nature.com/articles/d41...
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Andreas Prokop @poppi62.bsky.social · 10/04/2025
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 20/02/2025
Acabar un día de trabajo echando un ratico para hablar de lo divino, de lo humano y de los testículos de la mosca de la fruta fue una gozada. Gracias @raticosdeciencia.bsky.social
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 06/02/2025
nature.com
Mitochondria as you’ve never seen them — January’s best science images
The month’s sharpest science shots, selected by Nature’s photo team.
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Armando Iannucci @aiannucci.bsky.social · 29/01/2025
you.38degrees.org.uk/petitions/sa...
you.38degrees.org.uk
Save The Prince Charles Cinema
The future of the iconic Prince Charles Cinema in London’s West End is under serious threat! We are beyond disappointed that our landlords, Zedwell LSQ Ltd and their ultimate parent company Criterion...
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Nature @nature.com · 13/01/2025
A decade in, expansion microscopy is unlocking insights across biology and medicine go.nature.com/4adlNgg
go.nature.com
‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses
A decade in, expansion microscopy is unlocking insights across biology and medicine.
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Gavin Woodruff @weirdworms.bsky.social · 12/12/2024
Spread of yellow-bill-color alleles favored by selection in the long-tailed finch hybrid system www.cell.com/current-biol...
cell.com
Spread of yellow-bill-color alleles favored by selection in the long-tailed finch hybrid system
Carotenoid color ornaments play important roles in social signaling and species recognition. Hooper et al. show that bill-color variation in long-tailed finches is associated with genes controlling the metabolism of red pigments from yellow dietary precursors. Selection favoring yellow alleles is causing the trait to introgress between subspecies.
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Diego Sainz de la Maza @diegosainzdelamaza.bsky.social · 11/01/2025
Repurposing of a gill gene regulatory program for outer ear evolution
nature.com
Repurposing of a gill gene regulatory program for outer ear evolution - Nature
Nature - Repurposing of a gill gene regulatory program for outer ear evolution
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Manuel Ansede @manuelansede.bsky.social · 30/12/2024
Un experimento en un laboratorio español ha recreado la Tierra primitiva y han surgido protocélulas, un paso previo a los seres vivos. “No hay un soplo divino” en el origen de la vida, afirma el geólogo Juan Manuel García Ruiz elpais.com/ciencia/2024...
elpais.com
Un experimento recrea el mundo sin vida y surgen protocélulas, un paso previo a los seres vivos: “No hay un soplo divino”
Los investigadores, de un laboratorio español, observan por primera vez la aparición de compartimentos junto a los ingredientes básicos de los organismos
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FlyBase @flybase.bsky.social · 23/12/2024
New #GeneGroups subset: Metabolic Pathways! These manually curated reports aim to facilitate metabolic research in Drosophila by providing high-quality gene lists and visual representations of fly metabolic pathways, integrated with the other rich data in FlyBase.
FlyBase Metabolic Pathways report for CHITIN BIOSYNTHESIS.
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The Interactive Fly @interactivefly.bsky.social · 23/12/2024
Kaur, R., McGarry, A., Shropshire, J. D., Leigh, B. A., Bordenstein, S. R. (2024). Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality. Science, 383(6687):1111-1117 www.science.org/doi/10.1126/...
science.org
Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality
Wolbachia prophage manipulates sperm noncoding RNA and DNA vital for chromatin integrity and offers potential leads for vector control.
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