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Douglas W. Houston

@dhouston.bsky.social
67 followers 65 following 119 posts

Developmental Biologist. Professor, #UIowa Director, Developmental Studies Hybridoma Bank, @dshb-antibodies.bsky.social Views my own

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Reposted by Douglas W. Houston
Kurianlab @kurianlab.bsky.social · 26/08/2026
dshb.biology.uiowa.edu We should support and make better use of hybridoma bank Maintained by a small team at the University of Iowa’s Developmental Studies Hybridoma Bank
dshb.biology.uiowa.edu
Developmental Studies Hybridoma Bank - DSHB
High quality, low cost antibodies.
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Rebecca D. Burdine, PhD @rburdine1.bsky.social · 25/08/2026
This is bonkers.
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Reese Richardson @reeserichardson.bsky.social · 25/08/2026
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 14/08/2026
Cross-species reactivity isn’t guaranteed. Before ordering, check sequence conservation with BLAST, inspect structural context near an epitope, and search the literature for prior use. What else is on your checklist?https://dshb.biology.uiowa.edu/blog#post=choosing-an-antibody-with-confidence
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 15/06/2026
Spotted in @braincomms.bsky.social! Researchers from #CHEO Research Institute, among others, used 4 of DSHB's anti-MHC mAbs to examine how different genetic forms of CMS respond to a MuSK‑targeting antibody.
BA-F8 in blue
SC-71 in magenta
6H1 in green
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 14/06/2026
🔎 Spotted in @jci.org! Researchers at the University of Osaka, among others, used our anti-MHC [MF20] antibody to identify an SGCB splice-site mutation linked to dilated cardiomyopathy. 📄 tinyurl.com/2hdyfkys 🧫 dshb.biology.uiowa.edu/MF-20
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Diedre Reitz @diedrereitz.bsky.social · 09/06/2026
Happy to share that I will be joining the Biology Department and Holden Comprehensive Cancer Center at University of Iowa as an assistant professor in summer 2027! My lab will study how recombination is regulated to prevent non-allelic repair and genome rearrangements, and their relation to cancer.
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 04/06/2026
🔎 Spotted in #AdvancedScience! Researchers from #NYUGrossman and @dnanexus.bsky.social used our PAX7 antibody in a study mapping FAP signaling in skeletal muscle, revealing how cell populations communicate during homeostasis and regeneration. 📄 tinyurl.com/32k25caf 🧫 dshb.biology.uiowa.edu/PAX7
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 30/05/2026
🔎 Spotted in #npj Parkinson's Disease! Researchers from Buddhist Tzu Chi Medical Foundation, among others, used DSHB's anti-EN1 [4G11] mAb in a study on the development of cryopreservable dopaminergic progenitor cells from human stem cells to treat Parkinson’s disease in rats.
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 02/06/2026
🔎 Spotted in @physrep.bsky.social! Researchers from #NYIT College Of Osteopathic Medicine used DSHB's anti-MHCI [BA-F8], anti-MHCIIa [SC-71], anti-MHCIIb [BF-F3], and anti-PAX7 mAbs in a study on how Mustn1 gene ablation affects skeletal muscle repair in mice.
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University of Iowa Department of Biology @uiowabiology.bsky.social · 02/06/2026
We invite applications for multiple non-tenure-track Instructor positions that would begin on August 19, 2026. These positions will primarily contribute to instruction in the introductory biology laboratory curriculum for life sciences. For details and to apply, visit: jobs.uiowa.edu/faculty/view...
jobs.uiowa.edu
Faculty Requisition Details - Jobs@UIOWA: Search and Apply for Jobs at The University of Iowa
Jobs@UIOWA: The official place to search and apply for jobs at The University of Iowa.
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Roberto Mayor Lab @mayorlab.bsky.social · 16/05/2026
PL retweet. Developmental Biology Course (Quintay). More information: biodesarrollo.unab.cl
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University of Iowa Department of Biology @uiowabiology.bsky.social · 16/05/2026
Two new faculty members in the UI Department of Biology, Cathy Yea Won Sung and Anne Martin (@eannemartin.bsky.social), are advancing research on how the body develops and responds to disease. To read more, visit: clas.uiowa.edu/news/2026/04...
clas.uiowa.edu
New CLAS Biology faculty members earn national and local research support
Cathy Yea Won Sung and Anne Martin, who joined CLAS last fall, are advancing research in hearing loss and brain science with support from the National Institutes of Health and the Roy J. Carver Charit...
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Bailey Weatherbee @bailweatherbee.bsky.social · 01/05/2026
It's difficult to succinctly summarize a entire germ layer, but Aaron Zorn, Scott Rankin and I tried recently! Our "Endoderm at a Glance" review with @dev-journal.bsky.social is out now. shorturl.at/kHf9Y
Multipanel poster of "vertebrate endoderm development"
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Douglas W. Houston @dhouston.bsky.social · 27/04/2026
The chick embryos are always a crowd favorite!
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Igor Schneider @ischneider.bsky.social · 30/03/2026
Preprint out! Salamanders harbor a hypersensitive mTOR, thought to enable their remarkable limb regeneration. But do you need a special mTOR to regrow appendages? In Polypterus, we find that a canonical mTOR pathway supports full appendage regeneration. www.biorxiv.org/content/10.6...
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University of Iowa Department of Biology @uiowabiology.bsky.social · 28/03/2026
Congratulations to Biology Professor Maurine Neiman, PhD (@maurineneiman.bsky.social), on receiving the 2025 IDEA Award! Professor Neiman has spent her career expanding access and inclusion in the evolutionary biology community worldwide. Read more here: biology.uiowa.edu/news/2026/03...
biology.uiowa.edu
Biology Professor Receives 2025 IDEA Award
Biology Professor, Maurine Neiman, is the 2025 recipient of the IDEA Award given to a person at any career stage who has strengthened the ecology and evolutionary biology community by promoting access...
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Harv Virk @harv-virk.bsky.social · 09/03/2026
[1/6] Two new preprints out today from the OGA team. We've quantified the ethical costs of poor antibody validation for the first time — and developed a consensus plan to fix it. Thread 🧵
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 07/03/2026
#Dros26 Day 3 Did you know DSHB houses over 1600 Drosophila antibodies? Browse the collection and more: dshb.biology.uiowa.edu 📸 Drosophila germarium labeled with DSHB anti-Vasa (green) and anti-hts (magenta) 🧫 dshb.biology.uiowa.edu/anti-vasa 🧫 dshb.biology.uiowa.edu/1B1
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Douglas W. Houston @dhouston.bsky.social · 06/03/2026
From the meeting so far, here’s what seems in demand in the fly field; tell me I’m wrong. 1. Organelle markers ER, Golgi, endosomes, lysosomes, mitochondria. 2. Post translational modifications phospho-ERK, phospho-AKT, phospho-JNK, ubiquitin chains. 3. Cell-type markers Glia, intestinal cells
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John Wallingford @jbwallingford.bsky.social · 10/02/2026
Registration is OPEN for the 2026 Santa Cruz Meeting on Developmental Biology!!! Please spread the word! @mads100tist.bsky.social @socdevbio.bsky.social @bsdb.bsky.social @xenbase.bsky.social @isdb.bsky.social @devbiol.bsky.social @the-node.bsky.social scdb2026.sites.ucsc.edu
scdb2026.sites.ucsc.edu
Santa Cruz Developmental Biology Meeting
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 06/03/2026
If you're at #Dros26 and are interested in how cells change shape & move during morphogenesis & how different classic cadherins influence different cell behaviors, check out the talk by @saraheclark.bsky.social in Cell Biology: Cytoskeleton, Organelles, & Trafficking II Sat 9:15 🧪
Picture of SarahTalk slide title with images of testis defects
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 05/03/2026
Check out our booth at #Dros26!
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 05/03/2026
#Dros26 Day 1 Comment below your favorite DSHB antibody! 📸 Drosophila brain labeled with DSHB anti-Bruchpilot in blue 🧫 dshb.biology.uiowa.edu/nc82
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 20/02/2026
🔎 Spotted in Neurobiology of Disease! Researchers from #OhioStateUniversity and @wrightstateu.bsky.social used DSHB's anti-NF-M [2H3] and anti-SV2A mAbs in a study on a new SCN8A epileptic encephalopathy mouse model that depicts seizures and motor impairments seen in patients.
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 29/01/2026
🔎 Spotted in #ScientificReports by @natureportfolio.nature.com! Researchers from #NTUsg used DSHB's anti-CD8A mAb in a study on the role of ARL13B on ciliogenesis and related signaling pathways. 📄 tinyurl.com/2f86jfum 🧫 dshb.biology.uiowa.edu/CPTC-CD8A-1
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 28/01/2026
Spotted in @plosone.org! Researchers from Quillen College of Medicine and @hubrechtinstitute.bsky.social used DSHB's anti-Krt8 [TROMA-I] mAb in a study on Lgr5-positive duct cells in von Ebner’s glands as potential stem cells for regenerating posterior tongue taste buds in mice.
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 09/12/2025
Cooking up the next wave of Drosophila antibodies with Lori Wallrath 🧫🔬 Last day to visit DSHB at booth 1210! Don't miss out! #CellBio2025 #uiowa @ascbiology.bsky.social @embo.org
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Douglas W. Houston @dhouston.bsky.social · 04/12/2025
@dshb-antibodies.bsky.social is returning to ASCB #CellBio2025 stop by and check out what's new at booth 1210
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 07/11/2025
🔎 Spotted in Naunyn-Schmiedeberg's Archives of Pharmacology! Researchers from International University of Health and Welfare, Narita Campus used DSHB's anti-LAMP-1 [1D4B], anti-NCAM [AG1], and anti-synaptic-vesicles [SV2] mAbs in a study on mapping the Neuropeptide Y Y₁ receptor in the mouse brain.
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 25/11/2025
🔎 Spotted in #FASEBJournal! Researchers from @pullman.wsu.edu and @ohsunews.bsky.social used DSHB's anti-β-tubulin [E7] mAb in a study on the effects of Intralipid enhancing fetal sheep adipose growth. 📄 tinyurl.com/3zt6762j 🧫 dshb.biology.uiowa.edu/E7_2
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Molecular Instruments, Inc. @hcrimaging.bsky.social · 18/11/2025
With the HCR™ HiFi Encoder, @dhouston.bsky.social (@uiowabiology.bsky.social) ran two @dshb-antibodies.bsky.social mouse IgG1 antibodies directly from supernatant and achieved robust double-labeling using HCR™ Gold IF. 🔬 Ready to try HCR™ Gold IF? Get a free Starter Kit here: tinyurl.com/37dfdenf
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 10/11/2025
🔎 Spotted in @natbiotech.nature.com! Researchers from @hubrechtinstitute.bsky.social, among others, used DSHB's anti-integrin-β1 [AIIB2] mAb in a study on how an antibody derivative (scTS2/16) enhances human epithelial organoid growth. 📄 tinyurl.com/yu36mt6m 🧫 dshb.biology.uiowa.edu/AIIB2
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Douglas W. Houston @dhouston.bsky.social · 07/11/2025
Thanks to the folks at @HCRimaging for their nifty HCR HiFi encoders: "quantitative signal amplification of 1˚ antibodies for same-isotype multiplexing" 🔑@DSHB_antibodies can be tagged as supernatant, allowing mulplx wo/purification --> here are 2 trusted IgG1s used together
low-mag (5x) lateral view of a Xenopus tadpole; magenta is anti-skeletal muscle marker [12/101] staining the somites; green is anti-keratan sulfate [MZ15] staining notochord, both mouse IgG1s labeled with 546 and 647 encoders, respectively. Semi-cleared in 80% TDE.
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Maurine Neiman @maurineneiman.bsky.social · 06/11/2025
Nice highlight of new genome paper. ❤️ emphasis on leadership of ECR Potamomics team members @kylemcelroy.bsky.social @chelseahiggins.bsky.social @jsharbro.bsky.social Genome Duplication in a New Zealand Snail Holds Clues for the Persistence of (A)sexual Reproduction: academic.oup.com/gbe/article/...
academic.oup.com
Highlight: Genome Duplication in a New Zealand Snail Holds Clues for the Persistence of (A)sexual Reproduction
Why does sexual reproduction persist in so many species? This is a fundamental question in biology that, remarkably, remains a mystery. Sexual reproduction
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Maurine Neiman @maurineneiman.bsky.social · 05/11/2025
I am so proud & happy to see our Potamo genome assembly finally out there in the world! The process ended up being way more challenging than expected, but for some really cool reasons. ❤️🐌🧬 TLDR: Surprise! A VERY recent WGD. academic.oup.com/gbe/article/... Photo: C. Böck, ILIM, Mondsee, Austria)
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Patricia Schneider @patyschneider22.bsky.social · 04/11/2025
How do four-eyed fish see above & underwater? 🌤️🌊 Our new preprint reveals how Anableps rewired its retina for dual vision- evolution at work 👁️👁️ Kudos to @perezlouise.bsky.social @josanesousa.bsky.social @keylapruett.bsky.social + team! 🔗 tinyurl.com/3a8r9xy5
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 04/11/2025
🔎 Spotted in #Virulence by @tandfresearch.bsky.social! Researchers from #WSU Floyd College of Medicine used DSHB's anti-α-tubulin [AA4.3] mAb in a study on how the GCN-2 pathway triggers stress responses in C. elegans during infection. 📄 tinyurl.com/3anhfuhm 🧫 dshb.biology.uiowa.edu/AA4-3
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Society for Developmental Biology @socdevbio.bsky.social · 03/11/2025
🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 28/10/2025
🔎 Spotted in The Journal of Translational Medicine! Researchers from Sun Yat-sen University, among others, used DSHB's anti-Gingipain/P. gingivalis [61BG1.3] mAb in a study on how P. gingivalis drives cervical cancer metastasis. 📄 tinyurl.com/yzjhb6sx 🧫 dshb.biology.uiowa.edu/61BG1-3
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 23/10/2025
🔎 Spotted in Molecular Genetics and Genomics! Researchers from @ur-ctsi.bsky.social and @ucsandiego.bsky.social used DSHB's anti-HP1 [C1A9] mAb in a study on how CRIF1 suppresses tumors by opposing Ras signaling in Drosophila. 📄 tinyurl.com/4uscst5c 🧫 dshb.biology.uiowa.edu/C1A9
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Igor Schneider @ischneider.bsky.social · 14/10/2025
Hey Regen folks 👋 Excited to share that our single-nucleus RNA-seq dataset for Polypterus fin regeneration is now live at the Broad Institute portal! Dive in here: tinyurl.com/5bck22jx Big thanks to the team for making this happen—looking forward to seeing what you all discover!
UMAP of single nucleus RNAseq dataset of Polypterus fin regeneration
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 25/09/2025
🔎 Spotted in @natcomms.nature.com! Researchers from @uwmadison.bsky.social, among others, used DSHB's anti-MHC [MF 20] mAb in a study on how deleting ICAM-1 improves the immune resistance of stem-cell grafts. 📄 tinyurl.com/2s3pzheu 🧫 dshb.biology.uiowa.edu/MF-20
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 23/09/2025
🔎 Spotted in Autophagy by @tandfresearch.bsky.social! Researchers from #NationalTaiwanUniversity used DSHB's anti-α-Spec [3A9], anti-dlg [4F3], and anti-spitz mAbs in a study on Rab27’s role in regulating autophagy and lifespan in Drosophila.
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Douglas W. Houston @dhouston.bsky.social · 19/09/2025
Novel monoclonal antibodies against the C-terminal HEAT domain of Huntingtin biorxiv.org/content/10.110… Nice collaboration between @DSHB_antibodies , @LabScribbles and @thesgconline to make and characterize anti-HTT mAbs
biorxiv.org
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 18/09/2025
🔎 Spotted in Comparative Biochemistry & Physiology Part A! Researchers from @umassamherst.bsky.social and @utaustin.bsky.social used DSHB's anti-NKA-α-subunit [a5] mAb in a study on how red drum larvae adapt acid excretion to survive ocean acidification.
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 17/09/2025
🔎 Spotted in @mucosalimmunol.bsky.social! Researchers from #TongjiUniversity used DSHB's anti-dlg1 [4F3] mAb in a study on how bacterial membrane vesicles suppress CREB to regulate host immunity. 📄 tinyurl.com/yc7f97wk 🧫 dshb.biology.uiowa.edu/4F3-anti-dis...
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 12/09/2025
🔎 Spotted in #ScienceAdvances! Researchers from @uni-muenster.de, #OsnabrückUniversity, and @istaresearch.bsky.social used DSHB's anti-Rab7 mAb in a study on how RabGEF complexes evolved to regulate Rab GTPases in cell trafficking. 📄 tinyurl.com/4rnzfw4k 🧫 dshb.biology.uiowa.edu/Rab7
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 03/09/2025
🔎 Spotted in Proceedings B of @royalsocietypublishing.org! Researchers from @barnard-college.bsky.social, among others, used DSHB's anti-PDF [C7] mAb in a study on how artificial night light influences fruit fly behavior across sexes and genes.
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dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 20/08/2025
🔎 Spotted in Journal of Advanced Research! Researchers from Heilongjiang Bayi Agricultural University used DSHB's anti-Br-C core [25E9.D7] mAb in a study on how SUMOylation switches Kr-h1 from repressing to activating Br-C during insect development.
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