Sign in

Daniel Alber

@danielalber.bsky.social
137 followers 227 following 10 posts

Postdoc, Hughes Lab @ UPenn | PhD, Shvartsman Lab @ Princeton

PostsRepliesMedia
Reposted by Daniel Alber
Phil Abitua @ohnolog.bsky.social · 30/06/2026
Annual killifish continue to surprise us: they make neutrophils before almost every other cell type, even before gastrulation. Neutrophils usually arise from the lateral plate mesoderm (forming in cyan), but in killifish they are already patrolling around the embryo in gold. tinyurl.com/killiphil
720357
Reposted by Daniel Alber
Pierre Haas @lepuslapis.bsky.social · 29/04/2026
A fantastic #postdoc opportunity to join us in Dresden @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social or to join @biohub.org. Apply by the 20th of May!
014
Reposted by Daniel Alber
Alex Hughes Lab @hugheslabpenn.bsky.social · 03/04/2026
@lsprahl.bsky.social and Ronald Canlla in the lab just published a detailed study on remote-controlled epithelial budding morphogenesis. We can direct budding, tubule elongation, and perhaps branching in human kidney organoids via a light-activated RET receptor. www.biorxiv.org/content/10.6...
2248
Reposted by Daniel Alber
Alex Hughes Lab @hugheslabpenn.bsky.social · 13/12/2025
*New preprint alert* uncovering a mechanical pacemaker that synchronizes nephron formation with branching of the kidney's epithelial tubule tree. Read below to learn about this twisty journey lead by Sam Grindel and Sachin Davis in the lab. [Movie by Nils Lindstrom] www.biorxiv.org/content/10.1...
24010
Reposted by Daniel Alber
Aria 哲媛 Huang @azyhuang.bsky.social · 07/12/2025
if you are attending #CellBio2025 please check out the posters from our lab @hugheslabpenn.bsky.social. The lab will have a great showing this year featuring my talented colleagues @lsprahl.bsky.social @danielalber.bsky.social and many others!
095
Reposted by Daniel Alber
Kate Cavanaugh @katecavanaugh.bsky.social · 01/10/2025
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
1125881
Reposted by Daniel Alber
David Brückner @davidbrueckner.bsky.social · 27/09/2025
How do cells navigate up gradients of adhesive proteins? 🤔 Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood We show that passive friction directs cells & explains complex trajectories on gradients 👉 www.nature.com/articles/s41...
17626
Reposted by Daniel Alber
kuba sędziński @kuba-sedzinski.bsky.social · 22/09/2025
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
912336
Reposted by Daniel Alber
Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 19/09/2025
Peer pressure shapes the gut: latest publication in @pnas.org by @lepuslapis.bsky.social, @zhaoshh.bsky.social from @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social with colleagues from @flatironinstitute.org and Princeton University. www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Peer pressure shapes the gut
International research team develops mechanical model to explain the shaping of the fruit fly hindgut by forces from neighbouring tissues
1227
Reposted by Daniel Alber
Pierre Haas @lepuslapis.bsky.social · 19/09/2025
Now #published @pnas.org: "A model for boundary-driven tissue morphogenesis", a great #biophysics #devbio collaboration led by @danielalber.bsky.social @zhaoshh.bsky.social: doi.org/10.1073/pnas.2505160122 @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social @flatironinstitute.org
43812
Reposted by Daniel Alber
Mattia Serra @mattiaserra.bsky.social · 19/09/2025
📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia. @sreejithsanthosh.bsky.social biorxiv.org/content/10.1...
17619
Daniel Alber @danielalber.bsky.social · 18/09/2025
A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis! Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)
36922
Reposted by Daniel Alber
Pierre Haas @lepuslapis.bsky.social · 05/06/2025
Now #published in Phys. Rev. Lett. as an Editors' Suggestion: "Mechanics of poking a cyst" - the first paper from the PhD work of @zhaoshh.bsky.social. journals.aps.org/prl/abstract... @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
2255
Reposted by Daniel Alber
Eszter Posfai @eposfai.bsky.social · 22/03/2025
How many cells do you need to establish PCP? The magic number is 3! Beautiful work by Lena Basta in Danelle Devenport's lab. Happy to have contributed. www.science.org/doi/10.1126/...
science.org
Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous
For cells to polarize collectively along a tissue plane, asymmetrically localized planar cell polarity (PCP) complexes must form intercellular contacts between neighboring cells. Yet, it is unknown wh...
26120
Reposted by Daniel Alber
David Brückner @davidbrueckner.bsky.social · 14/03/2025
How do cells migrate without substrate, e.g. in embryogenesis, when extra-cellular matrix has not yet formed? Check out our paper in @cp-cellreports.bsky.social on zebrafish lateral mesendoderm migration, led by @stetavano.bsky.social @heisenbergcplab.bsky.social! www.cell.com/cell-reports...
1254
Reposted by Daniel Alber
Arthur Michaut 🔬🐣 @amichaut.bsky.social · 13/03/2025
I am delighted to share with you my first postdoc paper, which has now been published in @currentbiology.bsky.social! www.cell.com/current-biol... Thanks to everyone who contributed: A. Chamolly, @aurelienvilledieu.bsky.social, F. Corson and @jeromegros.bsky.
cell.com
A tension-induced morphological transition shapes the avian extra-embryonic territory
Michaut et al. show that the tension produced during epiboly elastically stretches the extra-embryonic (EE) territory, while the embryo proper (EP) remains unaffected. Although the whole epiblast (EP ...
55211
Reposted by Daniel Alber
Pierre Haas @lepuslapis.bsky.social · 07/03/2025
New #preprint: "Euler buckling on curved surfaces" arxiv.org/abs/2503.04303 @zhaoshh.bsky.social and I ask the question that Euler left open: How does an elastic line buckle within a (general) curved surface? @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
2306
Reposted by Daniel Alber
Pierre Haas @lepuslapis.bsky.social · 06/03/2025
New #preprint: "A model for boundary-driven tissue morphogenesis" arxiv.org/abs/2503.03688. A great collaboration with @danielalber.bsky.social @zhaoshh.bsky.social, Alexandre Jacinto, Eric Wieschaus, Stas Shvartsman. @flatironinstitute.org @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
15616
Daniel Alber @danielalber.bsky.social · 06/03/2025
Developmental systems have regions that deform actively or passively from their active neighbors. We use a ring of tissue as a model to investigate this boundary-driven morphogenesis in its biological context, learning something about gastrulation and possibly blastopore geometries in the process!
0122
Reposted by Daniel Alber
Eszter Posfai @eposfai.bsky.social · 05/03/2025
A duo of preprints on the dynamics of the first cell fate decision in mouse by Madeleine Chalifoux (first grad student in the lab!) and Maria Avdeeva (Flatiron). We use quantitative live imaging of key cell fate determinants to follow the segregation of inner cell mass and trophectoderm lineages.
12611