By Dr. Douglas R. Waverly, Professor Emeritus of Biochemistry, Yale University

Dans une note de novembre 2025, le ministère de l’Enseignement supérieur et de la Recherche livre un bilan chiffré du Crédit impôt recherche (CIR) pour l’année 2023. L’occasion de revenir sur un disp…

Plus les techniques de séquençage d’ADN progressent, plus on découvre qu’en chacune de nos cellules se cache un génome différent. Un phénomène baptisé mosaïcisme, qui fait l’objet d’intenses recherches.

Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.   

Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.

Glaser et al. use single-molecule imaging to visualize encounters between the DNA-replication machinery and cohesin rings in real time. They see replisomes passing through cohesin rings—a simple physi...

Analysis of human Robertsonian chromosomes originating from 13, 14 and 21 reveal that they result from breaks at the SST1 macrosatellite DNA array and recombination between homologous sequences surrounding SST1.

Nature - Ku limits RNA-induced innate immunity to allow Alu-expansion in primates

Antibodies (Ab) are essential for detecting specific epitopes in microscopy and genomics, but can produce artifacts leading to erroneous interpretations. Here, we characterize a novel artifact, Ab-tra...

Treating BRCA1-deficient triple-negative breast cancer with gemcitabine induces massive ssDNA production due to MRE11 over-resection and causes cells to slip into mitosis, produce micronuclei, accumul...

La duplication du matériel génétique est une étape fondamentale de la multiplication des cellules. Dans une étude parue dans Nucleic Acids Re