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Kathrin Marheineke, CNRS research director

@kathrinmarheineke.bsky.social
51 followers 42 following 3 posts

Senior researcher in the Prioleau lab, Institut Jacques Monod, CNRS, Université Paris Cité, France, DNA replication, replication timing, G4

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Kathrin Marheineke, CNRS research director @kathrinmarheineke.bsky.social · 18/08/2026
Our latest publication on DNA replication kinetics in different polyploid Xenopus species is now out in the FEBS Journal!😊 dx.doi.org/10.1111/febs...
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Reposted by Kathrin Marheineke, CNRS research director
Bruno Miroux @brunomiroux.bsky.social · 29/04/2026
Rapport de l'UNESCO (donnees.banquemondiale.org/indicateur/G...). Entre 1996 et 2023, 𝟩 𝘱𝘢𝘺𝘴 𝘴𝘶𝘳 𝟤𝟪 en Europe ont vu leurs investissements en recherche et développement 𝗯𝗮𝗶𝘀𝘀𝗲𝗿 en % du PIB. La Moldavie, la Biélorussie, la Roumanie, la Géorgie, l’Azerbaïdjan, la Fédération de Russie, et la 𝗙𝗿𝗮𝗻𝗰𝗲.
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Reposted by Kathrin Marheineke, CNRS research director
Bruno Miroux @brunomiroux.bsky.social · 29/04/2026
Investissement en R&D. Il a fallu 27 ans à 21 pays européens pour augmenter leurs dépenses en recherche et développement de 0,8 % en moyenne de leur PIB. Il faudra 30, 40, 50 ans à la France pour rattraper l’Autriche ou la Belgique!
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Reposted by Kathrin Marheineke, CNRS research director
mnprioleau.bsky.social @mnprioleau.bsky.social · 08/04/2026
Our latest publication is out! @narjournal.bsky.social academic.oup.com/nar/article-...
academic.oup.com
Transcription at an inducible common fragile site reveals replication origin strength hierarchy
Abstract. While genome-wide analyses in vertebrates suggest that transcription negatively regulates replication origin activation, thereby shaping the land
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Reposted by Kathrin Marheineke, CNRS research director
Thomas Balan @thomasbalan.bsky.social · 08/04/2026
First first-author paper out! 🎉 We show that the classically repressive mark H3K27me3 can be linked to active transcription through a newly identified reader complex 🤯 Really grateful to everyone involved in this project during my PhD! Thread below 👇
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Kathrin Marheineke, CNRS research director @kathrinmarheineke.bsky.social · 12/01/2026
We are pleased to share a new preprint on BioRxiv www.biorxiv.org/content/10.6.... @ijmonod.bsky.social.
biorxiv.org
Ploidy-dependent modulation of DNA replication kinetics in Xenopus
DNA replication in multicellular organisms follows a tightly regulated spatio-temporal program. Although the mechanisms underlying this replication program remain only partially understood, studies in...
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Reposted by Kathrin Marheineke, CNRS research director
CNRS Biologie @cnrsbiologie.bsky.social · 04/03/2025
#RésultatScientifique | Un équilibre subtil dans la duplication des chromosomes 🧬🔬 @kathrinmarheineke.bsky.social et ses collaborateurs révèlent que la réplication de l'ADN repose sur deux stratégies opposées et que Plk1 joue un rôle de coordination ! buff.ly/SNH5hl6
insb.cnrs.fr
Yin-Yang dans la duplication des chromosomes
La duplication du matériel génétique est une étape fondamentale de la multiplication des cellules. Dans une étude parue dans Nucleic Acids Re
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Kathrin Marheineke, CNRS research director @kathrinmarheineke.bsky.social · 30/01/2025
We are happy to share our latest study, published today in Nucleic Acids Research (doi.org/10.1093/nar/...) @ijmonod.bsky.social, @i2bcparissaclay.bsky.social. Many thanks to our collaborators !
doi.org
Dual DNA replication modes: varying fork speeds and initiation rates within the spatial replication program in Xenopus
Abstract. Large vertebrate genomes duplicate by activating tens of thousands of DNA replication origins, irregularly spaced along the genome. The spatial a
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