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Cindy L

@cuboidalhug.bsky.social
1.3K followers 540 following 153 posts
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Reposted by Cindy L
Eric Topol @erictopol.bsky.social · 05/08/2026
Severe Covid leads to persistent viral reactivation, with >10 different viruses noted in the first 40 days after hospital admission. Long Covid was specifically associated with reactivation of latent Anelloviridae virus @nature.com www.nature.com/articles/s41...
nature.com
Virus reactivation in acute and long COVID-19 - Nature
Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog...
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Cindy L @cuboidalhug.bsky.social · 08/07/2026
This review by Carolina López, just published in Nature Immunology, discusses persistence of RNA viruses past acute infection stages www.nature.com/articles/s41...
nature.com
Implications of RNA virus persistence for post-acute sequelae and chronic inflammatory syndromes - Nature Immunology
López and colleagues review recent evidence of RNA virus persistence and the associated consequences in terms of post-acute sequelae or chronic inflammatory syndromes.
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Cindy L @cuboidalhug.bsky.social · 16/05/2026
www.cell.com/cell/abstrac...
cell.com
Respiratory viral infections prime accelerated lung cancer growth
Severe COVID-19 is associated with an increased subsequent risk of lung cancer. Viral pneumonia induces durable lung epigenetic imprinting that promotes tumor-supportive neutrophils and impairs T cell...
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Cindy L @cuboidalhug.bsky.social · 25/03/2026
www.nbcnews.com/health/healt...
nbcnews.com
Pfizer Lyme vaccine shows more than 70% efficacy but misses key statistical goal
There hasn't been an approved Lyme disease vaccine for more than 20 years, after GSK pulled its shot because of a lack of demand.
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Cindy L @cuboidalhug.bsky.social · 22/02/2026
New huge (>800,000 people) study in Nature using genomic sequencing data finds association of EBV w/various diseases, including rheumatoid arthritis, MS, IBD, hypothyroidism, and T2D. Detectable EBV viral DNA is associated with 54 HLA alleles and 27 other genomic loci www.nature.com/articles/s41...
nature.com
Host control of persistent Epstein–Barr virus infection - Nature
Nature - Host control of persistent Epstein–Barr virus infection
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Reposted by Cindy L
Ezra S @ezra.zone · 05/01/2026
Long COVID advocate Meighan Stone needs our help, please share and donate if you can. Thanks to @phillyphile215.bsky.social for organizing. www.gofundme.com/f/keep-long-...
gofundme.com
Donate to Keep LC Campaign Founder Housed and Medically Stable, organized by Melissa Mazur
Friends, Long COVID Campaign Founder Meighan Stone needs our help! … Melissa Mazur needs your support for Keep LC Campaign Founder Housed and Medically Stable
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Reposted by Cindy L
Jonathan Wosen @jonathanwosen.bsky.social · 27/12/2025
A @statnews.com exclusive from me: Walter Koroshetz, director of NIH's neurological disorders institute, has been ousted. Yet another example of NIH leadership churn. His departure means that 13 of the agency's 27 divisions will have interim leaders. www.statnews.com/2025/12/27/n...
statnews.com
Director of NIH neurological disorders institute is ousted, adding to leadership churn
Walter Koroshetz, director of the National Institute of Neurological Disorders and Stroke, will soon be leaving his role, STAT has learned. His departure
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Reposted by Cindy L
Magnus Johansson @pgmj.bsky.social · 28/12/2025
"40 percent of MRI signals do not correspond to actual brain activity"; "Since tens of thousands of fMRI studies worldwide are based on this assumption, our results could lead to opposite interpretations in many of them.” www.tum.de/en/news-and-...
tum.de
40 percent of MRI signals misinterpreted
Interpretation of numerous MRI data may be incorrect: blood flow is not a reliable indicator of brain activity.
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Reposted by Cindy L
Scientific American @sciam.bsky.social · 26/12/2025
Immense progress in gene editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025
scientificamerican.com
Seven Feel-Good Science Stories to Restore Your Faith in 2025
Immense progress in gene editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025
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Cindy L @cuboidalhug.bsky.social · 19/12/2025
So amazing to see Whitney Dafoe able to speak again www.facebook.com/reel/6513673...
facebook.com
40K views · 2.2K reactions | Talking Again in 2025 I started eating again in 2024. After 11 years not eating a crumb of food or even drinking a drop of water. I got all fluids and nutrition from tu...
Talking Again in 2025 I started eating again in 2024. After 11 years not eating a crumb of food or even drinking a drop of water. I got all fluids and nutrition from tubes inserted into my body....
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Cindy L @cuboidalhug.bsky.social · 18/12/2025
yangtan.mit.edu/new-study-su...
yangtan.mit.edu
New study suggests a way to rejuvenate the immune system - Yang Tan Collective at MIT
Stimulating the liver to produce some of the signals of the thymus can reverse age-related declines in T-cell populations and enhance response to vaccination. Anne Trafton, MIT News As people age, the...
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Reposted by Cindy L
C.H. Romatowski @chromatowski.bsky.social · 06/12/2025
If you’re not already familiar w/ @boltsmag.org, it does terrific journalism at the local level across the U.S. The quality is wonderful and the stories are critical—putting Bolts in your timeline will make you so much more informed. Highly recommend. And rn following can help fund their work!
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Cindy L @cuboidalhug.bsky.social · 05/12/2025
New review from Akiko Iwasaki outlining the history of chronic illness in the wake of epidemics www.cell.com/trends/immun...
cell.com
The lingering shadow of epidemics: post-acute sequelae across history
The SARS-CoV-2 pandemic has drawn global attention to post-acute infection syndromes (PAIS), with millions affected by post-acute sequelae of COVID-19 (PASC, or Long COVID). While Long COVID is newly ...
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Cindy L @cuboidalhug.bsky.social · 01/12/2025
FYI - personal laminar flow & regular air filtration devices from @adamwong.bsky.social are on sale right now! I just wore my Air Fanta Wear for the first time at the hospital to supplement my N99 mask, and it was invaluable when I needed to drink water or (sadly) toss my cookies air-fanta.com
air-fanta.com
AirFanta air purifiers
Official website of AirFanta air purifiers.
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Cindy L @cuboidalhug.bsky.social · 27/11/2025
Nice review from Tim Henrich et al laying out a framework for thinking about how the complex landscape of prior, concurrent, and subsequent microbial infection (viral, microbial, fungal) may interact w Covid infection and whether that might play a role in Long Covid elifesciences.org/articles/106...
elifesciences.org
The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective
Unraveling mechanisms underlying post-acute SARS-CoV-2 sequelae (long COVID) and finding therapeutic solutions require a full understanding of the causative role of SARS-CoV-2 persistence and/or infec...
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Cindy L @cuboidalhug.bsky.social · 21/11/2025
Infection Connections: How past microbial incursions can lead to neurodegenerative diseases stanmed.stanford.edu/infections-l...
stanmed.stanford.edu
Why acute infections can lead to neurodegeneration
Researchers are uncovering the mysteries of why early-in-life acute infections can lead to neurodegenerative diseases in later years.
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Cindy L @cuboidalhug.bsky.social · 13/11/2025
@polybiorf.bsky.social is holding their Fall Research symposium tomorrow (Fri Nov 14). Register here to attend virtually —https://polybio.org/fall-2025-symposium/
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Reposted by Cindy L
Billy Hanlon @bhanlon15.bsky.social · 10/11/2025
With the RECOVER-NEURO clinical trial study results published today, looking forward to these RECOVER pathology studies planned for publication in 2026-2027
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Cindy L @cuboidalhug.bsky.social · 10/11/2025
Unsurprisingly, none of the “brain training interventions” tested in the RECOVER-NEURO Long Covid trial showed efficacy jamanetwork.com/journals/jam...
jamanetwork.com
Interventions for Cognitive Symptoms in Long COVID
This randomized clinical trial investigates if evidence-based rehabilitation strategies improve cognitive symptoms in persons with long COVID.
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Reposted by Cindy L
Adam Wong @adamwong.bsky.social · 03/11/2025
Hey everyone, I'm excited to share that AirFanta Wear is now live on air-fanta.com/products/air... You'll find a thorough product breakdown and a detailed video I made explaining a lot of things about it. (1/3)
air-fanta.com
AirFanta Personal Wearable Laminar Air Purifier
The AirFanta Wear is a personal wearable air purifier. Worn around the neck, it delivers a stream of HEPA-filtered air directly to your breathing zone, creating a personal bubble of clean air. Third-p...
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Cindy L @cuboidalhug.bsky.social · 29/10/2025
A nice article in Nature on how seemingly esoteric, basic science research has had an enormous impact on our lives… highlighting the importance of funding basic research whose practical applications are not yet readily apparent! www.nature.com/articles/d41...
nature.com
7 basic science discoveries that changed the world
Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government.
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Cindy L @cuboidalhug.bsky.social · 02/10/2025
This is cool 🙂
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Cindy L @cuboidalhug.bsky.social · 08/09/2025
Massachusetts Rebuffs RFK Jr. With Northeast Vaccine Accord www.msn.com/en-us/health...
msn.com
MSN
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Cindy L @cuboidalhug.bsky.social · 22/08/2025
www.bostonglobe.com/2025/08/22/m...
bostonglobe.com
Eight states, including Mass., met this week in a step toward public health independence from the federal government - The Boston Globe
Northeast states are seeking closer collaboration amid Trump's public health policies.
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Reposted by Cindy L
Dr. med. Hank Schiffers @leanhealth.bsky.social · 08/08/2025
UK: What if everyone had masked up? Analysis of app data has the answer: "Respirators would have dropped the rate of COVID transmission by an estimated factor of 9, compared with 0.6 for surgical masks. A factor of 9 is enough to put SARS-COV-2 into exponential decay! www.nature.com/articles/d41...
nature.com
What if everyone had masked up? Analysis of app data has an answer
Modelling study based on almost 250,000 positive COVID-19 tests in the United Kingdom shows that universal masking could have cut transmission markedly.
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Reposted by Cindy L
Brandy Zadrozny @brandyzadrozny.bsky.social · 09/08/2025
Exclusive: CDC Director Susan Monarez met with its vaccine-focused center to talk about yesterday’s shooting. I listened to a recording. Scientists and officials are shaken & pointing fingers at RFK Jr. Many said his vilification and misinfo turned them into targets. www.msnbc.com/opinion/anal...
msnbc.com
A deadly shooting at the CDC shook its scientists. Now they want answers from RFK Jr.
CDC Director Susan Monarez convened an online all-hands meeting of the agency division that focuses on vaccines, and employees called out Kennedy’s rhetoric specifically.
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Reposted by Cindy L
Dr. Lucky Tran @luckytran.com · 06/08/2025
At his confirmation hearing, RFK Jr claimed he wouldn’t take away vaccines. So far he has: Removed COVID vaccine recommendations Fired the CDC’s vaccine committee Replaced scientists with antivaxxers Cancelled vaccine hesitancy research Pulled $500m in mRNA vaccine research
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Science Magazine @science.org · 26/06/2025
Breaking news: The NIH yesterday moved to reinstate about 900 grants that a judge last week ruled had been canceled illegally because their topics, ranging from vaccine hesitancy or promoting diversity in the scientific workforce, had been blacklisted by the Trump administration. scim.ag/4lq9UrQ
scim.ag
NIH will reinstate 900 grants in response to court order
Projects touching on sensitive topics such as DEI had been illegally terminated, judge found
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Reposted by Cindy L
BK. Titanji @boghuma.bsky.social · 09/06/2025
More resistance from within the NIH Gift article www.theatlantic.com/health/archi...
theatlantic.com
An Uproar at the NIH
Jay Bhattacharya, the the agency’s director, has made a point of welcoming dissent. A letter from his officials will test that.
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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 18/05/2025
The FDA has approved Novavax COVID19 shots for those aged 65 and older or those 12-64 with medical conditions that put them at higher risk for severe COVID19. It doesn’t make sense to restrict it to ages 65 and up, but this is what happens when Congress confirms an anti-vaxxer to lead HHS.
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Tom Kindlon @tomkindlon.bsky.social · 04/05/2025
PolyBio @polybiorf.bsky.social Spring Symposium: Zoom seminar with 10 minute research updates from 33 researchers. Friday, May 16, 1100 ET / 1500 UTC polybio.org/spring-2025-... Register: us02web.zoom.us/webinar/regi... #longcovid #chronicillness #mecfs #lyme #cci
polybio.org
Spring 2025 Symposium Schedule - PolyBio Research Foundation
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Reposted by Cindy L
Carl Zimmer @carlzimmer.com · 02/05/2025
Time to catch up on the past week’s news about science and medicine in the US. Whew. 1/10
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Miles W. Griffis @mileswgriffis.bsky.social · 30/04/2025
Akiko Iwasaki and Harlan Krumholz call for Long COVID and chronic disease research funding in the WSJ: “Advancing this research is one of the most effective ways to improve the lives of the tens of millions of Americans with chronic diseases.” www.wsj.com/opinion/how-...
wsj.com
Opinion | How to Lead a Chronic Disease Revolution
Washington has an opportunity to help tens of millions.
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Reposted by Cindy L
Don Moynihan @donmoyn.bsky.social · 28/04/2025
New at Can We Still Govern: An anonymous NIH employee maps out the GOP budget gameplan to permanently gut our most important science agency. Impoundment, delay and red tape will create artificial "savings" that become the new benchmark for NIH budgets. donmoynihan.substack.com/p/the-nih-bu...
donmoynihan.substack.com
The NIH budget is on a fast track to disaster
An NIH insider explains what Republicans are likely to do next, and what we can do
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 11/04/2025
Kidney outcomes following COVID in children - from the NIH RECOVER initiative in @jama.com Network Open Usual caveats jamanetwork.com/journals/jam... #pedneph #NephSky
Figure 2.  Adjusted Hazard Ratios (HRs) for Kidney Outcomes in COVID-19–Positive vs –Negative Patients by Phase
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Eric Topol @erictopol.bsky.social · 03/04/2025
Another $2.6 billion in cuts to NIH are coming by next Tuesday www.statnews.com/2025/04/03/n... The shredded image fits
statnews.com
Trump administration orders NIH to eliminate $2.6 billion in federal contracts
At a chaotic time, the NIH is given a deadline of April 8 to make a 35% cut in services that may include specimen storage, genetic counseling, and administration.
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Eric Topol @erictopol.bsky.social · 02/04/2025
The vaccine against Shingles helps protect against dementia, results of a natural experiment, adding to prior evidence "implications are profound" New @nature.com www.nature.com/articles/d41... nature.com/articles/s41...
nature.com
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature
Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...
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Dr Satoshi Akima, FRACP @toshiakima.bsky.social · 02/04/2025
“A positive test for COVID-19 was associated with increased rates of diagnosis of various infections in the 12 months following an acute SARS-CoV-2 infection.” www.thelancet.com/journals/lan...
thelancet.com
Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study
Our results suggest that a positive test for COVID-19 (vs a negative test) was associated with increased rates of diagnosis of various infections in the 12 months following an acute SARS-CoV-2 infecti...
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Paul Nuki @paulnuki.bsky.social · 28/03/2025
Some very bad news: New modelling predicts up to 10 million additional HIV infections following aid cuts www.telegraph.co.uk/global-healt...
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Eric Topol @erictopol.bsky.social · 28/03/2025
Gearing up mRNA vaccines ("tolerogenic") to prevent autoimmune diseases, vital science that is currently under irrational and reckless attack www.nature.com/articles/s41...
nature.com
Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PDL1 within lipid nanoparticles - Nature Biomedical Engineering
Therapeutic tolerogenic antigen-presenting cells can be generated in vivo by delivering, via lipid nanoparticles, mRNA coding for the inhibitory protein programmed death ligand 1, as shown in mouse mo...
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Miles W. Griffis @mileswgriffis.bsky.social · 28/03/2025
🚨 BREAKING: Long COVID research grants rescinded earlier this week have been restored, according to researchers & patient reps. Advocates organized quickly yesterday in response to the news, helping reverse the decision. Exclusive in @thesicktimes.bsky.social thesicktimes.org/2025/03/28/u...
thesicktimes.org
UPDATE: RECOVER Long COVID pathobiology grants restored - The Sick Times
Long COVID research grants from the National Institutes of Health’s RECOVER program will be restored following news stories about their abrupt cancellations and advocacy to restore the funding, accord...
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It's ME(Jaime) @exceedhergrasp1.bsky.social · 27/03/2025
The administration has canceled 45 RECOVER #LongCOVID grants. These grants examined pathology, & were vital to understanding infection-associated chronic illness as a whole. Half of those with #LongCOVID at 6 mo. meet criteria for #MECFS. 🧪 cen.acs.org/policy/resea...
cen.acs.org
NIH cancels grants through flagship long COVID initiative
Termination ‘a waste of the money we’ve spent already’
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Reposted by Cindy L
Reuters @reuters.com · 27/03/2025
The US Department of Health and Human Services canceled around $12 billion in federal grants to states that were allocated during the COVID-19 pandemic. The grants were being used to track, prevent and control infectious diseases, said lawmakers reut.rs/41WVed3
reut.rs
US pulls back $12 billion in funding to state health departments
The U.S. Department of Health and Human Services canceled around $12 billion in federal grants to states that were allocated during the COVID-19 pandemic, the federal department and state officials said on Wednesday.
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Reposted by Cindy L
It's ME(Jaime) @exceedhergrasp1.bsky.social · 25/03/2025
Folks, very bad news for #LongCOVID. Deep breath. 29 awarded grants to do with COVID and Long COVID have been rescinded by NIH. 🧪 www.science.org/content/arti...
Science has learned that grant termination letters went out last night to principal investigators of 29 awards made by the National Institute of Allergy and Infectious Diseases (NIAID), including nine grants that were part of a program hoping to deliver antiviral drugs to prevent future pandemics. Other terminated grants involved research to develop improved COVID-19 vaccines and to address Long Covid, the mysterious lingering aftermath of some SARS-CoV-2 infections. “The research is being treated like we already have all the answers we will need in the future and that the current vaccines work well enough and don’t need improvement, which we know is not true,” says an investigator involved with one of the NIAID grants who asked not to be named for fear of retribution. “Some of the studies being canceled were attempting to make a pancoronavirus vaccine, which would hopefully be available the next time a novel coronavirus jumps species into humans.”
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Science Friday @scifri.bsky.social · 16/03/2025
90% of people diagnosed with pancreatic cancer die from the disease. That's why the medical community is excited about the results of a small trial in which nearly half of the pancreatic cancer patients who received an mRNA vaccine for the disease remained relapse-free three years later.
sciencefriday.com
A Vaccine For Pancreatic Cancer Continues To Show Promise
In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine for the disease had no relapse three years later.
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Eric Topol @erictopol.bsky.social · 12/03/2025
How does SARS-CoV-2 lead to the multisystem inflammatory syndrome in children, a rare, potentially fatal condition? www.nature.com/articles/s41... High levels of TGFβ interfere with the child's response to control Epstein Barr virus, leading to its reactivation and severe inflammation @nature.com
nature.com
TGFβ links EBV to multisystem inflammatory syndrome in children - Nature
Multisystem inflammatory syndrome following SARS-CoV-2 infection results from increased serum levels of TGFβ, which impairs the reactivation of virus-specific T cells.
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Christopher Barnes @cobarnes27.bsky.social · 06/03/2025
Excited to share the peer-reviewed version of our paper, which is out today!! Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern | Science Translational Medicine www.science.org/doi/10.1126/...
science.org
Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern
Bispecific antibodies incorporating a cross-reactive NTD-specific antibody are resilient to SARS-CoV-2 variants of concern.
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Stand Up for Science! @standupforscience.net · 07/03/2025
At a Stand Up for Science event? Show us your photos at #standupforscience2025 📣☀️🌎
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Marisa Kabas @marisakabas.bsky.social · 07/03/2025
The National Cancer Institute (part of NIH) released new guidelines for "controversial, high-profile or sensitive" keywords that require "review prior to publication" if included in a product or materials. Keywords include abortion, obesity, and peanut allergies.
Materials produced or authored by NCI staff that address topics that may be controversial, high profile, or sensitive must be sent to the NCI Clearance Team for review prior to publication.

Depending on the nature of the information, additional review and clearance by the NCI director, deputy directors, NIH, and HHS may be required. In some cases, the material will not need further review, but the NCI Clearance Team will share it with NCI leadership, NIH, and/or HHS for their awareness.

Examples of controversial or high-profile topics include, but are not limited to:

Cancer Moonshot
NCI budget
COVID-19
Vaccines
H5N1/bird flu
Opioids ,
Marijuana
Dietary guidelines/ultra-processed foods
Obesity
Stem cell or fetal tissue research
Abortion
Autism
Peanut allergies
Fluoride
Measles
Diversity/equity efforts
Gender ideology
Environmental justice
Discussion of federal policies
Topics of federal investigations
Issues concerning pending legislation
Topics that have received recent attention from Congress
Topics that have received widespread or critical media attention
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Bethany Brookshire @beebrookshire.bsky.social · 07/03/2025
Francis Collins Said science is of the people, by the people, for the people
Francis Collins, former director of the NIH, plays guitar in front of a crowd on the steps of the Lincoln memorial
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