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Ayush Midha

@ayushmidha.bsky.social
118 followers 294 following 25 posts

MD/PhD student at UCSF studying the metabolic adaptations to hypoxia in the Jain Lab. Member of UAW 4811. He/him

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Reposted by Ayush Midha
Gladstone Institutes @gladstoneinst.bsky.social · 22/09/2026
Ayush Midha, a graduate student in the Jain Lab, is uncovering how the body adapts when oxygen runs low—work that has surprising ties to cancer and fertility.
gladstone.org
Meet Gladstone: Ayush Midha
Ayush Midha, a graduate student in the Jain Lab, studies how the body's metabolism adapts to low oxygen—work that's uncovered backup energy pathways, potential fertility treatments, and a link between...
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Ayush Midha @ayushmidha.bsky.social · 03/09/2026
Relatedly, new review! @cp-trendsbiochem.bsky.social It's often assumed that oxygen is required for eukaryotic metabolism, but early eukaryotes emerged when oxygen was scarce. Their descendants use a remarkable diversity of anaerobic electron acceptors. Read more here: www.cell.com/trends/bioch...
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Ayush Midha @ayushmidha.bsky.social · 02/09/2026
New preprint! www.biorxiv.org/content/10.6... We uncovered surprising roles for a little-known metabolic pathway, branched-chain amino acid fermentation, with implications for hypoxia, mitochondrial dysfunction, alcohol toxicity, and fertility.
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Reposted by Ayush Midha
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 26/02/2026
“These awardees stood out for their scientific originality, rigor and dedication to asking important scientific questions. They reflect the strength and promise of the next generation of scientific leaders.” - Dr. Bai, director of the Weintraub Award. www.fredhutch.org/en/news/rele...
Top row, left to right: Keene Abbot, Gabriella Chua, Lifei Jiang, Won Jun Kim, Ruchita Kothari and Ayush Midha. Bottom row, left to right: Rohith Rajasekaran, Yusha Sun, Andrea Terceros, Wendy Valencia Montoya, Zachary Walsh and Peter Yoon.
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Ayush Midha @ayushmidha.bsky.social · 10/02/2026
I am excited to share our latest preprint showing that systemic hypoxia suppresses solid tumor growth: www.biorxiv.org/content/10.6... This has been a tremendous collaborative effort in the labs of Isha Jain @ishahjain.bsky.social and Hani Goodarzi @genophoria.bsky.social.
biorxiv.org
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Reposted by Ayush Midha
Vijay Ramani @vram142.bsky.social · 15/11/2024
The latest from our group, led by Megan Ostrowski and @martyyang.bsky.social, is now published in final form (www.cell.com/cell/fulltex...! Many thanks to our excellent peer reviewers for suggesting several experiments (including CAF-1 perturbation) to really improve the study =) #epigenetics
cell.com
The single-molecule accessibility landscape of newly replicated mammalian chromatin
By developing a long-read sequencing method to simultaneously map replication status and protein-DNA contacts in cells, Ostrowski, Yang, et al. show that newly replicated chromatin is enriched for unw...
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