Reposted by @elainetao.bsky.social
I'm so excited to have been part of this very fun project in collaboration with the Zhang lab! 💻💙
Please check out our preprint on this beautiful channel-like protein called XPR1 here at www.biorxiv.org/content/10.1...
biorxiv.org
KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1
XPR1 is emerging as the only known inorganic phosphate (Pi) exporter in humans, critical for Pi homeostasis, with its activity stimulated by inositol pyrophosphate InsP8 and regulated by neuronal scaf...