Reposted by Charles D Coxnatashaharvey.bsky.social @natashaharvey.bsky.social · 11/06/2026Join us in Adelaide this September for IVBM2026! The program is brilliant and the opportunities to interact with amazing researchers, clinicians, students and industry partners working on vascular biology are unmatched! Register now at ivbm2026.com 021
Reposted by Charles D CoxJournal of Cell Science @jcellsci.bsky.social · 09/06/2026Zijing Zhou, Charles Cox @charlesdcox.bsky.social @victorchang.edu.au and colleagues interrogate the molecular components of mechanically evoked currents in the Merkel cell line MCC13. Highlight: journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/... 111
Reposted by Charles D CoxBiophysical Society @biophysicalsoc.bsky.social · 08/06/2026Biophysical Society members! The 2026 ballot for the election of President-Elect, Secretary, and four members of Council is now available online. Cast your vote! buff.ly/FLF1Waz 021
Reposted by Charles D CoxBen Hogan @benjhogan.bsky.social · 30/05/2026Beyond time that we started seeing articles like this about the appalling state of Australia’s grant funding system……and peer review is just one problem that needs fixing. Australia’s erosion of peer review | Science www.science.org/doi/10.1126/...science.orgAustralia’s erosion of peer reviewThroughout the world, peer review serves as the cornerstone of the scientific enterprise, providing rigorous quality control and building the confidence that underpins progress for both science and so... 12113
Charles D Cox @charlesdcox.bsky.social · 05/05/2026Looking for a cell line that natively expresses PIEZO2 - we’d say avoid MCC13. Unlike Merkel cells the native mechanically-evoked currents in this line are largely carried by PIEZO1. And like many other cell lines that we’ve tested the slow components come from MDFIC/MDFI tinyurl.com/3mmnwhpptinyurl.comUnderstanding the molecular components of mechanically evoked currents in the Merkel cell line MCC13Merkel cells are epithelial cells involved in the discrimination of light touch. Situated in the skin, these specialised cells decode mechanical cues through the mechanosensitive ion channel PIEZO2. M... 052
Charles D Cox @charlesdcox.bsky.social · 10/04/2026Not the greatest ride for this one but happy with the end result - a sensory neuron specific protein that regulates PIEZO1/2. Lots of cool things left to show with this protein! MDFIC2 is a sensory neuron–specific PIEZO channel auxiliary subunit | PNAS www.pnas.org/doi/10.1073/...pnas.orgMDFIC2 is a sensory neuron–specific PIEZO channel auxiliary subunit | PNASPIEZO channels are critical for sensory mechanotransduction. While MyoD-family inhibitor proteins were identified as PIEZO1 auxiliary subunits, the... 091
Reposted by Charles D CoxJenny Stow @jennystowlab.bsky.social · 04/12/2025#NHMRC responses at #Estimates were deeply inadequate, uninformed and are not going to #SaveOzScience. #NHMRC has NOT requested more funding to save the majority of excellent science. Our science, our scientists and the public deserve better. Thankyou #DavidPocock and #DrMoniqueRyan. 095
Reposted by Charles D CoxPlessLab @plesslab.bsky.social · 26/11/2025To all trainees interested in channels and transporters: the joint FEBS/EMBO course will go ahead in Erice, Italy from May 13-19 2026: network.febs.org/posts/new-jo... Further details to come soon. Please share and repost. 01312
Reposted by Charles D CoxMelanie D. White @melaniedwhite.bsky.social · 25/09/2025Hey Mechanobiologists! Come and join us in sunny Brisbane for #MechBio2025 Nov 5-7. Registration is now open. Enjoy world-class science, a stellar speaker line-up, and relaxed Queensland vibes. 🧪🔬🌴 ausmb.org/meetings_202...ausmb.orgMechanobiology2025Join us for MechBio2025, the annual meeting of the Australian Society for Mechanobiology. November 5-7, 2025 at the University of Queensland, Brisbane. Featuring international keynote speakers and sho... 0154
Reposted by Charles D CoxArdem Patapoutian @ardemp.bskyverified.social · 09/04/2025Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...cnn.comNobel laureate: I owe America my success. Today, its scientific future is in danger | CNNDr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted... 15893488
Charles D Cox @charlesdcox.bsky.social · 31/01/2025I didn’t even know there was a PIEZO3 let alone a 4th one… 150
Charles D Cox @charlesdcox.bsky.social · 30/01/2025First pre-print of 2025! Collaborative effort with the Martinac and Feneley labs looking at the long term impact of Piezo1 deletion on cardiac function. Some very cool data, particularly a link between atrial stretch-Piezo1 channels and ANP release!! www.biorxiv.org/content/10.1...biorxiv.orgDeletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature deathMechanosensitive PIEZO1 channels have emerged as key transducers of mechanical forces in the cardiovascular system. In cardiomyocytes, we previously showed that PIEZO1 decodes mechanical cues driving ... 140
Charles D Cox @charlesdcox.bsky.social · 18/12/2024Stoked for and thankful to 🙏🏽 this wonderful crew! Amazing to get an NHMRC ideas grant at the 4th attempt!! Not only that but a second one led by our wonderful colleague Renjing_Liu !! #Fantastic2024 and it’s not even over yet 🥹 1110
Charles D Cox @charlesdcox.bsky.social · 12/12/20248 years apart - first as a post doc now as a PI. Pretty sure I haven’t aged a day 🫣 - congrats to post doc Zijing Zhou @victorchang.edu.au 051
Reposted by Charles D CoxGeorge Heath @georgerheath.bsky.social · 10/12/2024Please share, we have #PhD opportunities for anyone interested in filming the #Biophysics of life at the nanoscale. Full details at: heath-afm-lab.github.io/positions/ Projects based around developing and applying High-Speed Atomic Force Microscopy methods to understand molecular dynamics. 03517
Charles D Cox @charlesdcox.bsky.social · 03/12/2024First post- a photo of all the important people, celebrating a birthday and unbelievably good news from a grant funding round! 1120