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corrylab.bsky.social

@corrylab.bsky.social
1.2K followers 839 following 32 posts

Computational protein research group of Prof Ben Corry. We love molecular dynamics and all kinds of membrane proteins including ion channels, transporters and immune receptors ~Posts by group members

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corrylab.bsky.social @corrylab.bsky.social · 01/09/2026
Excited to share work by @yemilywang.bsky.social & Zhouyu Zhang, in a collab with PKU: Martini 3 CG sims overestimate lipid scrambling, predict it in proteins that don't scramble, and give anomalous binding, from low headgroup polarity. But small parameter refinements fix it. tinyurl.com/m3scramble
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corrylab.bsky.social @corrylab.bsky.social · 17/06/2026
Kudos to @ciarawallis.bsky.social & @yiechanglin.bsky.social for their elegant publication testing #AlphaFold for predicting protein oligomeric states including advice on when it is likely to do well and when it can fail. 🌟🎉🌟🎉#StructuralBiology #AI #Biophysics tiny.cc/oligos
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corrylab.bsky.social @corrylab.bsky.social · 27/05/2026
Excited to share this paper from @yiechanglin.bsky.social showing how lipids can move between bacterial membranes along the bridge like protein TamB. Also happy to be able to post the cool movie. 🎥🌟 #MDsimulations #StructuralBiology doi.org/10.1016/j.bp...
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corrylab.bsky.social @corrylab.bsky.social · 02/02/2026
Beginning 2026 with a flipping good paper🚀 OSCA/TMEM63 proteins do double duty: they’re ion channels and mechanically activated lipid scramblases helping reshape membranes and survive mechanical stress. 👏 @yiechanglin.bsky.social @charlesdcox.bsky.social doi.org/10.1038/s414...
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corrylab.bsky.social @corrylab.bsky.social · 16/09/2025
Great to see this paper with @elainetao.bsky.social out in print at the Biophysical Journal. Using Alphafold to study conformational transitions in 32 voltage-gated channel superfamily members #ionchannel #AI #StructuralBiology www.sciencedirect.com/science/arti...
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corrylab.bsky.social @corrylab.bsky.social · 27/07/2025
2 yrs ago @yiechanglin.bsky.social sent me this movie of lipid scrambling by OSCA1.2. Now we show it’s common to WT OSCA/TMEM63 proteins, mechanically activated, cholesterol dependent, and protects cells from damaging forces. Awesome collab with @charlesdcox.bsky.social &Zhang lab. tiny.cc/tmem63
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corrylab.bsky.social @corrylab.bsky.social · 17/06/2025
🌟 We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids 🌟 Join us at #scienceanu with amazing collaborators and great working conditions! Email me (karri.anu.edu.au) or apply here (tiny.cc/corry). Please share & repost!
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corrylab.bsky.social @corrylab.bsky.social · 27/03/2025
We show where chloroquine and peptides bind and help explain the polyspecific transport mechanism (2/2)
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corrylab.bsky.social @corrylab.bsky.social · 27/03/2025
Excited to share John's new work in Nat Coms! We demonstrate how PfCRT, a polyspecific peptide transporter, turns into a drug transporter for antimalarials like chloroquine and why this causes a fitness cost for the malaria parasite (1/2) tiny.cc/PfCRT
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corrylab.bsky.social @corrylab.bsky.social · 17/03/2025
Also bittersweet to announce the final work of @elainetao.bsky.social in our lab, using AF2 to study conformational transitions in 32 voltage-gated channel superfamily members 🤩 we're so excited to watch you Nav-igate the next steps of your career, Dr. Tao & are so proud of you 🎩 tiny.cc/VSD-AF2
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corrylab.bsky.social @corrylab.bsky.social · 16/03/2025
Thrilled to share our latest preprint from @yiechanglin.bsky.social & @ciarawallis.bsky.social showing that AF2-Multimer and AF3 can quickly & accurately predict the oligomeric states & structures of proteins (& maybe can identify multiple biologically relevant oligomeric states 👀) tiny.cc/oligomers
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corrylab.bsky.social @corrylab.bsky.social · 14/03/2025
Big congratulations to the very sharp @elainetao.bsky.social who submitted her PhD last week! Our greatest Nav channel expert is rumoured to be joining the dark side of Kv. #drtao #phdone @scienceanu.bsky.social 🔪🎆👩‍🔬👩‍🎓
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corrylab.bsky.social @corrylab.bsky.social · 10/02/2025
Big congratulations to @riottowow.bsky.social .bsky.social for winning an Anders Early Career Award at @lorneproteins.bsky.social ! Presenting his work on the lipid lined pore of the OSCA mechanosensitive channel. #lorneproteins2025
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corrylab.bsky.social @corrylab.bsky.social · 21/01/2025
Proud of our latest work w/ the Zhang lab showing from structure & simulation how XPR1, the only known human Pi exporter, is regulated by InsP8 & KIDINS220 + Pi selection & permeation through a channel-like “knock-kiss-kick” mechanism 🚪💋🦵 💻 by @ciarawallis.bsky.social & @riottowow.bsky.social
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corrylab.bsky.social @corrylab.bsky.social · 08/01/2025
I should have included one of the nice figures from the paper! rupress.org/jgp/article-...
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corrylab.bsky.social @corrylab.bsky.social · 18/12/2024
Season's Greetings from our (lab) family to yours! P.s. can you guess which lab member is which?? 🎄🎅🍪 Baking by @yiechanglin.bsky.social, Elaine Tao, ZhouYi Wang, @ciarawallis.bsky.social, + honorary member @caloflaherty.bsky.social ♥️
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corrylab.bsky.social @corrylab.bsky.social · 22/11/2024
I'm following the Friday trend to make my own word scramble. Mine is a bit of a historical mess, but lots of fun to try scholargoggler.com
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corrylab.bsky.social @corrylab.bsky.social · 22/11/2024
It's great to be back in Canberra with my wonderful (and prize-winning) lab talking about channels, transporters, lipids, and simulations while drinking boba #scienceanu
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