Large study suggests people’s genetics could ‘tip the balance’ on whether they would develop the illness

Senior Fellow in Public Health and Journalism, Center for Global Public Health at the University of California, Berkeley. I blog at Virology Blog (virology.ws). My academic position is largely funded ...

Pediatric Research - Distinct pro-inflammatory/pro-angiogenetic signatures distinguish children with Long COVID from controls

Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) patients share similar symptoms including post-exertional malaise, neurocognitive impairment, and memory loss. The neurocogni...

The cognitive behavioral model (CBmodel) (1,2) has dominated the world of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) since the 1990s. Accord...

Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may occur after infection. How often people develop ME/CFS after SARS-CoV-2 infection is unknown. Objective To determine the inci...

A year in review for chronic fatigue syndrome or ME/CFS findings evidence of cellular exhaustion in many levels caused by mitochondrial dysfunction.

Cardiovascular diseases (CVDs) are the leading cause of mortality among individuals with noncommunicable diseases worldwide. Obesity is associated with an increased risk of developing cardiovascular d...

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Five years after SARS-CoV-2 surfaced, scientists reflect and look ahead to the next threat

e activity is considered when working with people with long COVID, particularly when identifying triggers of post exertional symptom exacerbation. There are many potential mechanisms that could be dri...

symptoms, via reduced blood flow and cellular energy production. Postexertional malaise (PEM) is common and exercise therapy should not be recommended without addressing the underlying pathology. Cas...

litation. Methods: We conducted an international consultation on priorities for long COVID and rehabilitation with people living with long COVID, clinicians, researchers, and other key interest-hol...

Background Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In a 2021 review article on the pa...

Millions of Americans are struggling to return to work months after their initial bout with COVID-19, and the economic toll is staggering.

To date, 770 million people worldwide have contracted COVID-19, with many reporting long-term “brain fog”. Concerningly, young adults are both overrep…

British researchers have newly noted that women at midlife who have long COVID seem to get specific, and severe, symptoms, including brain fog, fatigue, new-onset dizziness, and difficulty sleeping.

Current evidence indicates that the prevalence of Long COVID in adults living with HIV may be high, suggesting the need for increased awareness and education of healthcare providers and policy makers. Evidence on whether HIV positivity increases the risk of Long COVID is limited and inconclusive, highlighting a need for further research to clarify this potential association.

Introduction: Orthostatic intolerance is highly prevalent in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and is caused by an abnormal reduction in cerebral blood flow (CB...

Since the pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the leading trigger for myalgic encephalomyelitis/chronic …

A new finding of post-exertional malaise in 20% of people with fibromyalgia might be an overestimate, but when post-exertional malaise is present, extreme caution is needed around prescribing exercise...

In this longitudinal, case-controlled, cohort design study, authors show that post-exertional malaise is associated with severe exercise-induced myopathy, local and systemic metabolic disturbances and...

Fibrin drives inflammation and neuropathology in SARS-CoV-2 infection, and fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with long COVID.

Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

By David Tuller, DrPH Cochrane has just given the finger to the international ME/CFS community. After jerking everyone around and promising for five years t ...

By David Tuller, DrPH The BMJ recently published a review of interventions for Long Covid that--surprise!--recommended CBT and a rehabilitation program as t ...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Health minister and Nice commit to work to improve patient outcomes after landmark inquest