Gabandé-Rodríguez, Soto-Heredero and colleagues identify an accumulation of cytotoxic CD4+ T cells producing CCL5 in the bone marrow during aging, linked to age-associated myelopoiesis. CCR5 blockade ...

Event is likely to be largest in at least 1,000 years and will pile extra heat into a world already in a climate crisis

Fearless molecular biologist who revealed the workings of antibodies and memories.

Limbs have distinct sidedness, with dorsal-ventral flexure allowing diverse movements that permit nuanced articulation and function. Hawkins et al. demonstrate that the genetic foundation of this patt...

The process of DNA replication is inherently asymmetric. While the leading strand is synthesized continuously, the lagging strand is copied in small fragments, the Okazaki fragments, requiring the ...

The Max Delbrück Center’s Global Fellow Postdoctoral Program aims to establish a structure to foster greater interdisciplinary research among different labs. Our first winners of the three-year fellow...

Total body irradiation is routinely used for myeloablation before a mouse hematopoietic cell transplant. Widespread transition from 137Cs γ irradiator…

Job Description We are seeking a highly motivated postdoctoral researcher to join our laboratory to study the early steps of development of childhood B-cell Acute Lymphoblastic Leukemia (B-ALL). The p...

The biochemist introduced the first heel-prick tests for newborn babies in Spain, protecting infants from life-changing metabolic conditions.

Shortages of donor blood for transfusions can have severe medical consequences, and ex vivo production of red blood cells offers a potential solution. Here authors developed synthetic EPO receptors, w...

Roger Penrose, now 93, never shied away from wild ideas and the ensuring debates. The first full-length biography reveals more about the mathematician and the man.

Cylinders discovered in 2004 are inscribed with the earliest known examples of letters, say archaeologists.

Haematopoietic stem cell (HSC) clonogenic activity, lineage output, lineage commitment and somatic mutation rates are influenced by the underlying disease, patient age, extent of genetic defect correc...

Earth’s old animals are in decline. Despite this, emerging research is revealing the vital contributions of older individuals to cultural transmission, population dynamics, and ecosystem processes and...

A few months after ChatGPT was released, the neural network pioneer Terrence Sejnowski wrote about coming to grips with the shock of what large language models (LLMs) could do: “Something is beginning...