iiinova — where your digital self keeps evolving

Slim Mzoughi @sleemmz.bsky.social · 13/07/2026

🔬 Come build something new with us in NYC 🗽. We're hiring a Postdoctoral Fellow and an Assistant Scientist at Mount Sinai. We study functional heterogeneity, cell-state plasticity, and tumor evolution, and we're looking for curious, ambitious scientists ready to tackle bold questions. Please share!

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Slim Mzoughi @sleemmz.bsky.social · 25/06/2025

📢 Exciting news: The Mzoughi Lab will launch in January 2026 at the Icahn School of Medicine at Mount Sinai in NYC! Young talents and cell plasticity enthusiasts—stay tuned for upcoming opportunities!

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Slim Mzoughi @sleemmz.bsky.social · 12/02/2025

🔈We've got the cover of the 2nd NG issue for 2025🙌 Read about the cover: In the comment👇 Also check out our research briefing🚨 (link below): nature.com/articles/s41... nature.com/articles/s41...

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Chris Tape @christophertape.bsky.social · 11/02/2025

Nice paper from @sleemmz.bsky.social et al underscoring the importance of stem cell transdetermination in CRC. RXR, YAP, and AP1 signalling collectively control access to revival stem cells and inhibition of these nodes limits plasticity to improve chemosensitivity. www.nature.com/articles/s41...

nature.com

Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer - Nature Genetics

Oncofetal (OnF) reprogramming, driven by YAP and AP-1, induces phenotypic plasticity and therapy resistance in WNT-dependent colorectal cancer (CRC). Targeting the OnF state in combination with chemot...

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Chris Marine Lab @marinelab.bsky.social · 10/02/2025

So happy to see this live, Slim! Congratulations to you, Ernesto and the whole team for your resilience, vision and creativity!

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Slim Mzoughi @sleemmz.bsky.social · 10/02/2025

Thrilled to share my 1st brainchild, out today @naturegenet.bsky.social 🚀 Been hearing a lot about fetal-like states lately? We uncover the molecular mechanisms, functional significance and clinical relevance of #oncofetal reprogramming in CRC. www.nature.com/articles/s41... (rdcu.be/d9iSN) a 🧵

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Nature Portfolio @natureportfolio.nature.com · 26/11/2024

The Human Cell Atlas is yielding detailed maps of human tissues and systems throughout life, along with methods to handle single-cell data. Four scientists reflect in Nature on how the project is transforming our understanding of human biology. 🧪

go.nature.com

Cellular atlases are unlocking the mysteries of the human body

Scientists reflect on insights from the Human Cell Atlas.

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Eslam Katab @eslamkatab.bsky.social · 23/11/2024

A shared meal, a kiss on the cheek: these social acts bring people together — and bring their microbiomes together, too. …. It is fascinating how our microbiome is shaped! www.nature.com/articles/d41...

nature.com

Your friends shape your microbiome — and so do their friends

Analysis of nearly 2,000 people living in remote villages in Honduras reveals who’s spreading gut microorganisms to whom.

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Slim Mzoughi @sleemmz.bsky.social · 20/11/2024

Happy with the move to🦋 ! I hope we can use this platform as a fresh start to foster meaningful scientific discussions and collegiality, rather than superficial praise or unproductive disagreements.

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