Sign in

Joanna Chustecki

@chusteckisci.bsky.social
413 followers 159 following 46 posts

Postdoc Associate at University of Oxford, currently studying mitochondrial dynamics in plant development Also on the bird app

PostsRepliesMedia
Reposted by Joanna Chustecki
Journal of Cell Science @jcellsci.bsky.social · 30/09/2026
Jin-Mo Gu, Andreas Nebenführ and colleagues discover that accelerated organelle movements can indirectly affect the motility of other organelles in plant cells. Highlight: journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/...
168
Joanna Chustecki @chusteckisci.bsky.social · 23/09/2026
New preprint! @mitomaths.bsky.social expanded our model of mitochondrial dynamics to comprehensively characterise potential behaviours. We look through the plant lense: even under compounded genomic stress plants show rebalanced but still near-optimal behaviours! www.biorxiv.org/content/10.6...
biorxiv.org
111
Joanna Chustecki @chusteckisci.bsky.social · 20/09/2026
"The breadth of topics presented & active participation of ECRs reflected the vibrant and collaborative nature of the ICPMB community. Plant mito biology is well positioned for further advances in both fundamental plant research and for future crop breeding" academic.oup.com/pcp/advance-...
academic.oup.com
Highlights from the 14th International Conference for Plant Mitochondrial Biology: Current Trends and Future Directions
Abstract. Plant mitochondrial biology is undergoing a rapid transformation driven by advances in genomics, structural biology, quantitative imaging, and ge
010
Reposted by Joanna Chustecki
Advanced Research + Invention Agency (ARIA) @aria-research.bsky.social · 09/09/2026
Meet the 19 teams we’re funding in Precision Mitochondria. They’ll work on developing a genetic toolbox to make mitochondria programmable for the first time, empowering scientists to robustly investigate the link between mitochondrial health + disease. Find out more here: link.aria.org.uk/jz4
link.aria.org.uk
Funded projects | Precision Mitochondria
We're funding 19 teams of world-leading experts spanning fields from mitochondrial and engineering biology to nanotechnology. Explore the projects we're funding in the Precision Mitochondria programme.
071
Reposted by Joanna Chustecki
Robert Arkowitz @robertarkowitz.bsky.social · 03/09/2026
www.molbiolcell.org/doi/abs/10.1...
molbiolcell.org
Organelle partitioning in the multi-budding yeast Aureobasidium pullulans | Molecular Biology of the Cell
Cellular organelle content is fairly constant within a given cell type. This is accomplished in part by ensuring equitable organelle partitioning during division. Much of our understanding of organell...
044
Reposted by Joanna Chustecki
bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 04/08/2026
A Modular Platform for Purification of Organelle-associated Mitochondria Reveals Functional Specialization at Organelle Contact Sites www.biorxiv.org/content/10.64898/20…
054
Reposted by Joanna Chustecki
Rory Osborne @drosborneplantsci.bsky.social · 08/07/2026
If you're attending the @sebiology.bsky.social conferennce, make sure to join myself and @robynemm.bsky.social for day 2 of the Plant Epigenetics session! Featuring somatic memory, epigenetic perception, immunity and developmental plasticity 😍🌿🧬
0147
Reposted by Joanna Chustecki
Nitish Dua @nitishdua.bsky.social · 27/06/2026
Really hyped to share our pre-print on mtDNA replication-fission ! @nanigrotjahn.bsky.social (doi: doi.org/10.64898/202...) 🧵with details below ⤵️
doi.org
ATAD3A structurally links mtDNA replication and mitochondrial fission
Mitochondrial function depends on the maintenance of its genome, and disruptions in copy number and distribution are hallmarks of mitochondrial disorders. Mitochondrial DNA (mtDNA) replication is spat...
25622
Reposted by Joanna Chustecki
Sainsbury Laboratory Cambridge University (SLCU) @slcuplants.bsky.social · 27/05/2026
Mechanical forces & cell shape guide how plant stomata form🥬👄 @leoserra.bsky.social & Euan Smithers from @robinsonsci.bsky.social's team uncover how the interplay between cell shape & mechanical stress influences the orientation of stomata doi.org/10.1016/j.ce... www.slcu.cam.ac.uk/news/mechani...
Time-lapse images of adaxial side of PM-YFP cotyledons showing new stomatal divisions occurring between 1 and 2 days after germination (DAG). Newly formed stomata are highlighted in magenta at 2DAG. Imaging by Leo Serra.
211449
Reposted by Joanna Chustecki
bioRxivpreprint @biorxivpreprint.bsky.social · 13/06/2026
Endosomal mRNA transport coordinates local mitochondrial bioenergetics during polar fungal growth www.biorxiv.org/content/10.64898/20…
034
Reposted by Joanna Chustecki
Molecular Biology and Evolution @molbioevol.bsky.social · 30/04/2026
@lfceriotti.bsky.social et al. investigate the rewiring of organellar translation in the holoparasitic Balanophoraceae, revealing extreme changes in the anciently conserved machinery of plant organellar translation. 🔗 doi.org/10.1093/molbev/msag077 #evobio #molbio #PlantSky
MBE | Reshaping organellar translation and tRNA metabolism: the consequences of photosynthesis loss and massive horizontal gene transfer

Photo: Tuber and two inflorescences of the holoparasitic plant Lophophytum pyramidale collected from Parque Nacional Calilegua, Argentina
166
Reposted by Joanna Chustecki
Juan C. Landoni @jclandoni.bsky.social · 24/04/2026
We're hiring! 🔬🏔️ Looking for curious, open-minded, and multidisciplinary #PhD candidates to research at the intersection of #mitochondria, #metabolism, #imaging & #physiology, with the #Alps as a backdrop. Sounds like you or someone you know? Link below! @fbm-unil.bsky.social @unil.bsky.social
15743
Reposted by Joanna Chustecki
Viktoriia Voloboeva @viktoriiavoloboeva.bsky.social · 01/04/2026
Tiny shoot apical meristems demand precision and patience. During my PhD, I measured oxygen directly by inserting a 3 or 10 µm microsensor into the meristem. Very happy that this work is now published in Molecular Plant. Link: doi.org/10.1016/j.mo...
1235
Reposted by Joanna Chustecki
Rachael DeTar @organelledchaos.bsky.social · 01/04/2026
Our undergraduate researcher Jennifer Marron @jennamarron.bsky.social is graduating this semester and looking for a job! If you are looking for a candidate with molecular and computational biology skills as well as great time management and work ethic, look no further! Otherwise, please repost!
032
Reposted by Joanna Chustecki
FocalPlane @focalplane.bsky.social · 30/03/2026
We are excited to launch a new webinar series, Macro to micro: quantitative plant imaging across scales, organised by @ajcellbio.bsky.social and @joemckenna.bsky.social. Our first webinar will featured talks from @blace.bsky.social and Simon Gilroy. focalplane.biologists.com/2026/03/30/n...
FocalPlane features… quantitative plant imaging across scales
Thursday 30 April, 15:00 BST (UTC+1)
Organised by Alex Johnson and Joe McKenna 
Image of Beatrice Lace (University of Freiburg)
Multiplexing and Endogenous Fluorescence Discrimination Using FLIM in Plants
Image of Simon Gilroy (University of Wisconsin–Madison)
Do plants feel pain? How imaging has brought plant wound signaling into the human timescale.
#FocalPlaneFeatures           focalplane.biologists.com
Image of a segmented root
14432
Joanna Chustecki @chusteckisci.bsky.social · 07/03/2026
It’s not just plant mitochondria that remain small and lack mtDNA- functional specialisation of axonal mitochondria www.biorxiv.org/content/10.1...
biorxiv.org
040
Reposted by Joanna Chustecki
Kin Pan Chung @kinpanchung.bsky.social · 03/03/2026
Mitochondria can indeed be inherited from the father! 🍀 In this new study, we uncovered the molecular mechanisms underlying mitochondrial inheritance in Nicotiana tabacum. @natplants.nature.com doi.org/10.1038/s414...
doi.org
High-frequency biparental inheritance of plant mitochondria upon chilling stress and loss of a genome-degrading nuclease - Nature Plants
Maternal inheritance of mitochondria breaks down in the cold when a mitochondrial DNA degrading nuclease is defective, resulting in biparental inheritance that can rescue mitochondrial mutations and g...
12912
Joanna Chustecki @chusteckisci.bsky.social · 27/02/2026
Check out this article summarising the recent Flora in Focus conference! Summing up some wonderful advances in plant imaging 🌱🔬💥
025
Joanna Chustecki @chusteckisci.bsky.social · 12/02/2026
All together now 🗣️🗣️ : mitochondrial dynamics are vital *even in plants*! 🗣️🗣️ Fantastic work looking looking at the prime candidate for the mysterious & elusive plant mito fusion factors: MIRO1 The momentum for plant mito dynamics is picking up 💪🏻 www.nature.com/articles/s41...
nature.com
Mitochondrial fusion safeguards stomatal defence in plants - Nature Plants
Plants close their stomata to block pathogen entry, but how this defence is supported at the organelle level remains unclear. Our study reveals that immune signalling promotes MIRO1-dependent mitochon...
0207
Reposted by Joanna Chustecki
Vinay Shukla @vinayshukla.bsky.social · 21/01/2026
PhD opportunity in the newly minted RO2T Respiration Group! Please share! Interested in root biology, oxygen dynamics, imaging & modelling? We’re recruiting a PhD student at the University of Nottingham. Deadline 15th February. jobs.nottingham.ac.uk/Vacancy.aspx... #plantscijobs #plantscience
12228
Reposted by Joanna Chustecki
Journal of Cell Science @jcellsci.bsky.social · 14/01/2026
In their Review, Rahul Kumar Verma, Somya Madan and Richa Rikhy discuss mitochondrial dynamics and signalling in stem cell differentiation. journals.biologists.com/jcs/article/...
Schematic showing interaction of mitochondrial fusion with Notch signaling. (A) Mouse embryonic stem cells (ESCs) have fragmented mitochondria and active Notch signaling. The Notch intracellular domain (NICD) accumulates in the nucleus, where it regulates CBF1-dependent transcription, resulting in maintenance of fragmented mitochondria. Increased capacitative Ca2+ entry and calcineurin A (CnA) activity stimulate Notch1 signaling, maintaining the stem cell state. During differentiation of ESCs into cardiomyocytes, Notch signaling is reduced, which is accompanied by mitochondrial fusion due to increased expression of the fusion proteins Opa1, Mfn1 and Mfn2 (Mfn1/2). (B) Drosophila neural stem cells (NSCs) have fused mitochondria and active Notch signaling. Increased NICD in the nucleus results in Suppressor of Hairless [Su(H)]-mediated transcription and increased Opa1 and Marf expression. Opa1 and Marf maintain fused mitochondria and support the formation of intermediate progenitor cells. Created in BioRender by Rikhy, R., 2025. https://BioRender.com/wqklpid. This figure was sublicensed under CC-BY 4.0 terms.
142
Reposted by Joanna Chustecki
Dan Sloan @sloanevolab.bsky.social · 13/01/2026
Great collaboration with the Sanchez-Puerta lab and colleagues! @lfceriotti.bsky.social @organelledchaos.bsky.social @jumpinggenomes.bsky.social @chusteckisci.bsky.social @achristensenphd.bsky.social (and others not on bsky) www.biorxiv.org/content/10.6...
biorxiv.org
Reshaping Organellar Translation and tRNA Metabolism: The Consequences of Photosynthesis Loss and Massive Horizontal Gene Transfer
The transition to holoparasitism in plants precipitates the loss of photosynthesis, fundamentally altering the selective landscape acting on organellar genomes. These changes raise questions about the...
154
Joanna Chustecki @chusteckisci.bsky.social · 11/01/2026
More evidence for the sphere of influence model- local mtDNA quality determines local mitochondrial function, even when part of an interconnected network- and drives selection! Beautiful work
020
Reposted by Joanna Chustecki
Iain Johnston @mitomaths.bsky.social · 09/01/2026
1. Apply for one of the positions below (lab or theory) by Jan 18th 2. Learn interdisc skills and discover cool new things about how mitochondria move and socialise 3. Explore some of Norway's beautiful nature (both the below, Rundemanen and Gullfjellet, <10km from work)
058
Joanna Chustecki @chusteckisci.bsky.social · 19/12/2025
Apply here for an incredible mentor, cool science and a beautiful city in which to work! ✨
000
Reposted by Joanna Chustecki
Juan C. Landoni @jclandoni.bsky.social · 17/11/2024
🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪 www.annualreviews.org/content/jour... #Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA
Review titleReview sections graphicSub compartments of mitochondria graphicMitochondrial.dynamics graphic
715545
Reposted by Joanna Chustecki
Rory Osborne @drosborneplantsci.bsky.social · 04/12/2025
So happy to see this work finally online! In this Research Review, I discuss the emerging roles of H3K27me3 writers (the enzymes that lay it down) and erasers (the enzymes that remove it) in controlling plant adaptation 🌿🌡️❄️🦠 nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com
Finding balance: the dynamic interplay between H3K27me3 writers and erasers in regulating environmental plasticity and memory
Subject to an ever-changing world, plants must respond to harmful conditions and environmental fluctuations. Their evolutionary success can be attributed to their plasticity in both perceiving and in...
22515
Joanna Chustecki @chusteckisci.bsky.social · 01/12/2025
Check out the editorial 'Plant Mitochondrial Biology' special issue; home to our paper 'Running on empty: Mitochondria Without DNA Exhibit Differential Motility&Connectivity' @achristensenphd.bsky.social Editorial onlinelibrary.wiley.com/doi/10.1111/... Paper onlinelibrary.wiley.com/doi/10.1111/...
052
Reposted by Joanna Chustecki
Jean-Yves Tinevez @jytinevez.bsky.social · 20/11/2025
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji. It ships many new features, detailed below, but that are articulated around the following:
418275
Reposted by Joanna Chustecki
John Ngo @johntngo.bsky.social · 22/09/2025
🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/
622497
Joanna Chustecki @chusteckisci.bsky.social · 15/09/2025
A privilege to attend the 9th annual Computational Plant Biology workshop last week at @slcuplants.bsky.social heard inspiring talks, got direct help and advice with pipeline bottlenecks and explored some very pretty places!
020
Joanna Chustecki @chusteckisci.bsky.social · 13/09/2025
Nice to see a small summary of our research findings in the Plantae Research Weekly! ☺️🌱
041
Reposted by Joanna Chustecki
Ivan Radin @radinbio.bsky.social · 08/09/2025
This might be one of the simplest images I captured, but very fascinating nonetheless, as it shows how tight the cytoplasm in a plant cell is. The cytosol and all other organelles are squished between the plasma membrane (magenta) and the central vacuole (its membrane is green) #MicroscopyMonday
The image shows one straight magenta line and, close to it, another wavy green line.
711730
Reposted by Joanna Chustecki
Sam Lewis, Ph.D. @samlewis.bsky.social · 29/08/2025
I'm happy to share new work in collaboration with Elena Koslover's lab! First author Keaton developed a mathematical framework for diffusion of soluble material through mitochondrial networks. Then, Lewis lab PhD candidate Camryn used live cell imaging to parameterize... 1/3
1136
Reposted by Joanna Chustecki
Alexey Amunts @amunts.bsky.social · 29/08/2025
Mitochondrial transfer is a fascinating phenomenon where cells shuttle mitos. The therapeutic potential is compelling and observational science is solid but the mechanism is a black box. Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
23312
Reposted by Joanna Chustecki
Plant Physiology @plantphys.bsky.social · 17/07/2025
Cytoplasmic inheritance: The transmission of plastid and mitochondrial genomes across cells and generations (Kin Pan Chung) doi.org/10.1093/plph... #PlantScience
031
Joanna Chustecki @chusteckisci.bsky.social · 07/08/2025
The only meeting I’ve ever been to with a fun fair at night! #brumforever #NGS2025
030
Joanna Chustecki @chusteckisci.bsky.social · 06/08/2025
It’s been a wonderful meeting so far at #NGS2025 the ECR community is a great place to be right now, and we’ve had some fascinating talks and workshops. Loved presenting my work on mtDNA and mito dynamics #plantscience
0101
Reposted by Joanna Chustecki
Harry Low’s Lab @lowlab.bsky.social · 28/07/2025
Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏 www.imperial.ac.uk/media/imperi...
imperial.ac.uk
02030
Joanna Chustecki @chusteckisci.bsky.social · 24/07/2025
Got papped yesterday at the @biology.ox.ac.uk research showcase spreading the good word about mitochondrial dynamics! So fun being in the new LaMB building and interacting with psych/bio colleagues 🌱🧠 (You can check out the paper I was soapboxing about here: onlinelibrary.wiley.com/doi/10.1111/...)
094
Reposted by Joanna Chustecki
UNL Center for Biotechnology @biotechunl.bsky.social · 15/07/2025
Congrats, Joanna! New article out in collaboration with our Microscopy Core!
011
Reposted by Joanna Chustecki
Journal of Cell Science @jcellsci.bsky.social · 15/07/2025
In their Review, Sangheeta Bhattacharjee and Benu Brata Das discuss the roles of topoisomerases in mtDNA maintenance and repair, and highlight their potential as therapeutic targets. journals.biologists.com/jcs/article/...
Spatial organization of mitochondrial nucleoids. (A) Human mitochondrial DNA (mtDNA) is a covalently closed, circular DNA molecule composed of heavy (outer) and light (inner) DNA strands. Each strand has its own origin of replication, referred to as OH and OL, respectively. mtDNA contains 16,569 nucleotides and encodes 37 genes, including two rRNAs and 22 tRNAs (designated by letters). These genes are vital for protein synthesis within mitochondria. (B) Left, live-cell microscopy image of MCF7 breast cancer cells stained with Picogreen (DNA, green) and MitoTracker red (mitochondria, red) taken by S.B. of our laboratory. mtDNA nucleoids appear yellow. Right, a schematic diagram shows mtDNA wrapped in nucleoid-associated proteins, which form core and peripheral complexes within the nucleoid. These protein complexes are essential for the replication, transcription, translation and maintenance of mtDNA within mitochondria.
132
Reposted by Joanna Chustecki
KatajistoLab @katajistolab.bsky.social · 14/07/2025
Proudly presenting Simon’s @simonsterson.bsky.social‬ paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism @naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
nature.com
Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells - Nature Metabolism
Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.
47022
Reposted by Joanna Chustecki
Alan Christensen @achristensenphd.bsky.social · 14/07/2025
Thank you to David Macherel, Jose Gualberto and Hakim Mireau for organizing the 2024 ICPMB meeting and the special issue of Phys. Plant. And to Olivier Keech, Allan Rassumsson and Olivier Van Aken for organizing the 2022 ICPMB meeting where I first met Joanna and the seeds of this work germinated.
001
Joanna Chustecki @chusteckisci.bsky.social · 14/07/2025
An exciting day! Our latest work is now out; we ask the question, are there any differences between plant mitochondria with and without mtDNA? 🌱 onlinelibrary.wiley.com/doi/10.1111/... (1/9)
onlinelibrary.wiley.com
(ID‐ICPMB05) Running on Empty: Mitochondria Without DNA Exhibit Differential Motility and Connectivity
Plant mitochondria are in continuous motion. While providing ATP to other cellular processes, they also constantly consume ATP to move rapidly within the cell. This movement is in part related to tak....
3166
Reposted by Joanna Chustecki
Dan Sloan @sloanevolab.bsky.social · 04/07/2025
Happy to share that this study is now published. Check it out! journals.plos.org/plosgenetics...
042
Reposted by Joanna Chustecki
Sam Lewis, Ph.D. @samlewis.bsky.social · 18/04/2025
I'm thrilled to share that our story is now out in Science Advances! 🎉 We use quantitative imaging to map the mito central dogma, define translation hubs in the mitochondrial matrix, and show that they're replaced by Mitochondrial Stress Bodies (MSB) when mtRNA processing is perturbed 1/4
89836
Reposted by Joanna Chustecki
Susan Shao @sshaolab.bsky.social · 10/04/2025
How do cells achieve an optimal mitochondrial distribution? Excited to share a piece of this puzzle: www.science.org/doi/10.1126/...
science.org
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution
ARMC1 partitions between distinct outer mitochondrial membrane complexes and the cytosol to control mitochondrial distribution.
15820
Joanna Chustecki @chusteckisci.bsky.social · 07/04/2025
Nice to be back in sunny Münster to help out with the GoPMF Imaging Workshop 2025!
120
Reposted by Joanna Chustecki
mitotalks.bsky.social @mitotalks.bsky.social · 01/04/2025
MITOtalks this week
0108