Reposted by The Batlle LabEACR - European Association for Cancer Research @helloeacr.bsky.social · 22/06/2026Already excited for next year's congress? Make sure to save the date in your calendars, and sign up for #EACR2027 updates! eepurl.com/dvcaQf 033
Reposted by The Batlle LabIRB Barcelona @irbbarcelona.org · 22/06/2026📌 Join us in our plenary #seminar this week, with Hugo Snippert, from @themaximacenter.bsky.social. 🤝 Host: @batllelab.bsky.social Register here ➡️ shorturl.at/pWcSN #IRBBarcelona #CancerResearch 031
The Batlle Lab @batllelab.bsky.social · 23/06/2026Thrilled and grateful 🙏 🌟We have been awarded a new ERC Adv Grant to launch #PlasticCRC, a project that will explore how tumour cell plasticity 🧬🔄 drives adaptation and resistance in metastatic CRC. 🙌🏼Many thanks to everyone in the lab and collaborators. ➡️Looking forward to the science ahead! 281
The Batlle Lab @batllelab.bsky.social · 12/02/2026🙏Thank you to Ràdio Barcelona for the Toresky Award 🎙️ 🏆Although it recognizes a “personality,” the lab’s discoveries are the result of my team’s dedication and passion 🥼PhDs, postdocs, & senior members work relentlessly to make possible the breakthroughs being recognized today 🙌 ✨Huge thanks to all 0103
The Batlle Lab @batllelab.bsky.social · 12/12/2025At the Tumor Heterogeneity, Plasticity & Therapy conference in Leuven! 🌟🇧🇪 Huge thanks to the organizers for the invitation. 🙌 Tumour heterogeneity and plasticity are critical areas that are reshaping how we understand therapy resistance and tumour evolution.🔬 www.vibconferences.be/events/tumor...vibconferences.beTumor Heterogeneity, Plasticity and Therapy (3rd edition)10-12 December 2025, Leuven, Belgium 180
Reposted by The Batlle LabIRB Barcelona @irbbarcelona.org · 26/11/2025Yesterday in Valencia Dr. @nlbigas.bsky.social received the 2025 Premio Rei Jaume I in Biomedical Research. Her work on how cancer mutations arise and evolve has earned major recognition! Congratulations, Núria! 🙌 #ReiJaumeI #CancerResearch @cerca.cat @icreacommunity.bsky.social @bbglab.bsky.social 0178
Reposted by The Batlle LabSociedad Española de Bioquímica y Biología Molecular (SEBBM) @sebbm.bsky.social · 25/11/2025PODCAST: Conversaciones del Premio Nobel Producida por Nobel Prize Outreach y la @fundacionareces.bsky.social, los podcast de la serie "Conversaciones del Premio Nobel " proponen acercar a la sociedad española los logros de estos científicos y sus historias personales. 011
Reposted by The Batlle LabThe Batlle Lab @batllelab.bsky.social · 07/11/20251/17 🧵 🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇 ➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC). Very proud of the team and efforts behind it. www.nature.com/articles/s41...nature.comTGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages - Nature GeneticsTargeting TGFBR1 in transplantable mouse colorectal tumor organoids improves response to anti-PD-L1 therapy. Mechanistically, TGF-β abrogates clonal expansion of T effector and memory phenotypes and i... 14714
Reposted by The Batlle LabThe Batlle Lab @batllelab.bsky.social · 27/10/2025Our recent Cancer Discovery study (Centonze et al.) shows that within hours, metastatic CRC cells switch from an EMP1⁺ invasive state to an LGR5⁺ stem-like program, highlighting that Plasticity is a dynamic, regulated cell-state decision #Bluetorial below👇🏼 #KRAS #Plasticity #ColorectalCancer 0196
Reposted by The Batlle LabCNAG @cnag-eu.bsky.social · 17/11/2025⏳Countdown to the 14th #CNAGSymposium! 🗣️Don’t miss Dr. Eduard Batlle from @irbbarcelona.org (@icreacommunity.bsky.social), sharing his insights on “Plasticity, therapy resistance, and immune evasion in metastatic colorectal cancer” 🗓️Dec 16, BCN 📎 www.cnag.eu/events/14th-... @batllelab.bsky.social 065
Reposted by The Batlle LabThe Batlle Lab @batllelab.bsky.social · 23/10/2025🧵1/17 📣Thrilled to share our latest study just out in Cancer Discovery! ➡️ aacrjournals.org/cancerdiscov...aacrjournals.orgA plastic EMP1⁺ to LGR5⁺ cell state conversion as a bypass to KRAS-G12D pharmacological inhibition in metastatic colorectal cancerAbstract. Inhibitors of the oncogene KRAS hold promise for treating metastatic CRC (mCRC). Here we show that a selective, covalent small molecule inhibitor of the active (ON) conformation of RAS-G12D,... 14116
Reposted by The Batlle LabIRB Barcelona @irbbarcelona.org · 07/11/2025🔬 #ColorectalCancer evades #immunotherapy using a dual barrier: A study by #IRBBarcelona & @cnag-eu.bsky.social reveals how metastatic colorectal tumours block the immune system through two complementary mechanisms. 📰 @natgenet.nature.com ➡️ bit.ly/49BJaC0 #IRBScience @batllelab.bsky.social 🧪 2174
The Batlle Lab @batllelab.bsky.social · 07/11/20251/17 🧵 🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇 ➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC). Very proud of the team and efforts behind it. www.nature.com/articles/s41...nature.comTGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages - Nature GeneticsTargeting TGFBR1 in transplantable mouse colorectal tumor organoids improves response to anti-PD-L1 therapy. Mechanistically, TGF-β abrogates clonal expansion of T effector and memory phenotypes and i... 14714
Reposted by The Batlle LabVIB Training & Conferences @vibtrainconf.bsky.social · 05/11/2025Could understanding how #cancer cells talk to their neighbours help stop the disease? Johanna Joyce, a regular at #VIBConf, will uncover these new ways to predict, prevent, and treat cancer. Join #THPT25 before 26 Nov and decode the therapies that outsmart cancer: vibbio.tech/3Le9oAr #tumorbiology 253
The Batlle Lab @batllelab.bsky.social · 06/11/2025At the Oncode Annual Conference 2025. Fantastic Meeting. Thanks for the invite. Catching up with many colleagues and friends. www.oncodeinstitute.nl/events/oncod...oncodeinstitute.nlOncode Annual Conference 2025 | Oncode InstituteRegistration is closed!There are roadworks, so the public transport route is different from previous years. For up-to-date information, please use Reisplanner | GVB or Plan je reis met het OV en deelv... 000
Reposted by The Batlle LabEACR - European Association for Cancer Research @helloeacr.bsky.social · 29/10/2025Registration for Cancer Cell Plasticity closes on Monday 03 November! Join us online to explore the fundamental mechanisms that control cancer cell plasticity at multiple biological levels: eacr.org/conference/c... 055
The Batlle Lab @batllelab.bsky.social · 29/10/2025🙌🏼 What a fantastic meeting this was! Congrats to everyone who contributed! #EESOrgan @events.embo.org 🔝 A huge thank you to the organizers for the invitation, and for putting together such a memorable conference. 📸 A remarkable aspect was seeing together five generations of Clevers’ Lab!! 030
The Batlle Lab @batllelab.bsky.social · 29/10/2025📣 Last chance to register for the EACR virtual conference on Cancer Cell Plasticity You’ll gain new insights into fundamental mechanisms controlling cancer cell plasticity as well as innovative approaches to target them ➡️https://eacr.org/conference/cancercellplasticity2025 @helloeacr.bsky.social 010
The Batlle Lab @batllelab.bsky.social · 27/10/2025Our recent Cancer Discovery study (Centonze et al.) shows that within hours, metastatic CRC cells switch from an EMP1⁺ invasive state to an LGR5⁺ stem-like program, highlighting that Plasticity is a dynamic, regulated cell-state decision #Bluetorial below👇🏼 #KRAS #Plasticity #ColorectalCancer 0196
Reposted by The Batlle LabThe Batlle Lab @batllelab.bsky.social · 24/10/2025➡️ This important video was missing from yesterday’s #Bluetorial. CRC organoids under treatment with KRAS inhibitor RMC-9945, rapidly acquire a LGR5+ cancer stem cell-like phenotype, allowing them to bypass KRAS inhibition, and eventually resume growth. Centonze et al., in #CancerDiscovery #AACR 0136
The Batlle Lab @batllelab.bsky.social · 24/10/2025➡️ This important video was missing from yesterday’s #Bluetorial. CRC organoids under treatment with KRAS inhibitor RMC-9945, rapidly acquire a LGR5+ cancer stem cell-like phenotype, allowing them to bypass KRAS inhibition, and eventually resume growth. Centonze et al., in #CancerDiscovery #AACR 0136
The Batlle Lab @batllelab.bsky.social · 23/10/2025🧵1/17 📣Thrilled to share our latest study just out in Cancer Discovery! ➡️ aacrjournals.org/cancerdiscov...aacrjournals.orgA plastic EMP1⁺ to LGR5⁺ cell state conversion as a bypass to KRAS-G12D pharmacological inhibition in metastatic colorectal cancerAbstract. Inhibitors of the oncogene KRAS hold promise for treating metastatic CRC (mCRC). Here we show that a selective, covalent small molecule inhibitor of the active (ON) conformation of RAS-G12D,... 14116
The Batlle Lab @batllelab.bsky.social · 17/10/2025Lab Celebrations are in order. More news to come 071
Reposted by The Batlle LabIRB Barcelona @irbbarcelona.org · 24/04/2025🏆 El lliurament dels Premis Dia del Biòleg 2025 de @biolegscat.bsky.social tindrà lloc demà 25 d'abril a les 16:30 h al COACB. Enhorabona a tots els guardonats! Entre ells, @batllelab.bsky.social, de l'#IRBBarcelona! 🔴 Segueix la cerimònia en directe aquí: f.mtr.cool/egtmfleqvu 153
The Batlle Lab @batllelab.bsky.social · 25/04/2025Estic molt agraït pel reconeixement rebut. Em sap greu no haver pogut assistir a l’acte de lliurament del premi i a la celebració del Dia del Biòleg. Afortunadament, l’equip hi ha pogut ser present en representació. 040
The Batlle Lab @batllelab.bsky.social · 25/04/2025Un placer y un honor dar la 28a Lección Conmemorativa Teófilo Hernando. Amigos, colaboradores y científicos a los que respeto y admiro entre los ponentes anteriores. 030
The Batlle Lab @batllelab.bsky.social · 24/04/2025It’s a pleasure to present our work at CRG’s annual symposium. Many good friends and colleagues around. 050
Reposted by The Batlle LabIRB Barcelona @irbbarcelona.org · 20/02/2025🗣️«Estamos empezando a entender cómo se genera la #metástasis y a ser capaces de prevenirlas y eliminarlas cuando ya se han producido». 🗨️ @batllelab.bsky.social #DebatesCaixaResearch 082
The Batlle Lab @batllelab.bsky.social · 14/02/2025En Sevilla, en las Jornadas conjuntas CIBERONC CIBER_OBN. @ciberisciii.bsky.social 010
Reposted by The Batlle LabIRB Barcelona @irbbarcelona.org · 12/02/2025🗣️Debate #CaixaResearch: “La incidencia de #CáncerdeColon aumenta entre los jóvenes" Con @batllelab.bsky.social y @tonigabaldon.bsky.social (@irbbarcelona.org), Angélica Figueroa (INIBIC) y Elena Élez (@vhio.bsky.social). 🗓️ Miércoles 19 febrero 🕖 19 h 💻 online ➡️ tinyurl.com/bdda8tsr 🧪 062
Reposted by The Batlle LabEMBO @embo.org · 12/02/2025Hello everyone on Bluesky! 🧪 We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond. Read more: www.embo.org/about-embo/m... 422574
Reposted by The Batlle LabIRB Barcelona @irbbarcelona.org · 29/01/2025🧪 We are #hiring! 🔵 #Postdoctoral Fellows: @batllelab.bsky.social, Stefanie Wculek 🔵 Personnel Administration Expert 🔵 #FlowCytometry Technician 🔵 Public Procurement Officer 🔵 Programme Secretary ➕ℹ️ here ➡️ s.mtrbio.com/vmyqtfohpj #IRBJobs #Jobs #PostdocJobs #ScienceJobs 067
Reposted by The Batlle LabAngélica_Figueroa_Lab @afigueroainibic.bsky.social · 04/02/2025👉 Debate CaixaResearch “La incidencia de cáncer de colon aumenta entre los jóvenes” Ilusionada por compartir debate con @batllelab.bsky.social y @tonigabaldon.bsky.social 📅 Miércoles 19 de febrero de 2025, a las 19 h. Apúntate aquí👇👇👇 bit.ly/3E5vHoq 073
The Batlle Lab @batllelab.bsky.social · 06/02/2025caixaresearch.org/es/debates-c...caixaresearch.orgDEBATES CaixaResearch - Aumento del cáncer de colon en jóvenesInvestigadores expertos debaten sobre el incremento de casos del cáncer de colon en los jóvenes en los DEBATES CaixaResearch de la Fundación ”la Caixa”. 000
The Batlle Lab @batllelab.bsky.social · 19/01/2025About to give the Keynote Lecture at the The #KSMetastasis25 @KeystoneSymp on Tumor Microenvironment: Metastasis and the Host. The location at Banff is impressive. Thank you Manuel Valiente and Julio Aguirre-Ghiso for the invitation! 0141
The Batlle Lab @batllelab.bsky.social · 16/01/2025Big day today for Maria Salvany! Defence about to start! 020
The Batlle Lab @batllelab.bsky.social · 07/01/2025www.lavanguardia.com/ciencia/2025...lavanguardia.comEl científico Joan Massagué recuerda a su mentor, Joan Guinovart, fallecido a los 77 añosEl 1 de enero, la ciencia perdió a Joan Guinovart, un líder ejemplar y un mentor excepcional que deja una profunda huella en la comunidad científica y en la sociedad. 070
Reposted by The Batlle LabAnna Obenauf @obenaufa.bsky.social · 06/01/2025🌟Keystone Cancer Immunotherapy conference 2025 🌟 #KSCancerImmune25 Speaker Highlight #1 Dr. Carl June, the father of CAR T-cell therapy and 2024 #BreakthroughPrize winner will share critical advances in cancer immunology in his talk “Cell Therapies: Current State of the Art”. 1251
Reposted by The Batlle LabEACR - European Association for Cancer Research @helloeacr.bsky.social · 06/01/2025What practical measures can we take to help break the glass ceiling for women in cancer research? Listen to episode 10 of The Cancer Researcher Podcast for an insightful discussion with three expert guests including @johannajoyce.bsky.social: magazine.eacr.org/how-to-break... 0167
Reposted by The Batlle LabAnna Obenauf @obenaufa.bsky.social · 06/01/2025🌟Keystone Cancer Immunotherapy conference 2025 🌟 Speaker Highlight #2 at #KSCancerImmune25: Dr. Ton N. Schumacher @nkinl.bsky.social will discuss how T cells detect tumors in “Dissecting T Cell Recognition of Cancer.” Don’t miss his cutting-edge immunology insights! 1206
The Batlle Lab @batllelab.bsky.social · 03/01/2025elpais.com/espana/catal...elpais.comMuere a los 77 años Joan Guinovart, fundador y exdirector del Institut de Recerca Biomèdica (IRB)El científico y catedrático, Creu de Sant Jordi en 2014, fue una figura clave en el ámbito de la bioquímica 022
The Batlle Lab @batllelab.bsky.social · 03/01/2025www.ara.cat/ciencia-medi...ara.catJoan Guinovart: una raó per no descansarEl traspàs de Joan Guinovart és per a tots els que l’estimàvem una bufetada. Ho veiem venir, però no ens hi aveníem i al final ens ha agafat per sorpresa. 021
The Batlle Lab @batllelab.bsky.social · 03/01/2025www.lavanguardia.com/ciencia/2025...lavanguardia.comLo que la ciencia le debe a Joan Guinovart, fallecido a los 77 añosSi la ciencia en Catalunya y en el conjunto de España ha logrado la hazaña de salir de la mediocridad y alcanzar la excelencia en los últimos 25 años, ha sido en 000
The Batlle Lab @batllelab.bsky.social · 03/01/2025www.abc.es/sociedad/joa...abc.esJoan Guinovart, el científico que salió del laboratorioFundó y dirigió el IRB de Barcelona, pero sobre todo este bioquímico fue una figura clave en el despertar de la ciencia en España 032
Reposted by The Batlle LabJens Puschhof @jenspuschhof.bsky.social · 05/12/2024#Organoid #Starterpack #1 is now full (go.bsky.app/RmXgs6d). Time for #Organoids #2/2: go.bsky.app/JVA5H2a Already many great new arrivals & finds such as @batllelab.bsky.social, @saurlab.bsky.social & more! 72513