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Thibault Mayor

@cellsandprots.bsky.social
844 followers 413 following 56 posts

Prof of Biochemistry & Molecular Biology at @ubc and @msl Our team focuses on proteostasis and yeast cell biofactories ❤️ ubiquitin, chaperones & proteomics 💙 outdoor, repast, electro-rock & traveling 🇨🇭🇨🇦 mayor51.wixsite.com/mayorlab

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Thibault Mayor @cellsandprots.bsky.social · 02/09/2026
Doing proteomics on different yeast biofactories showed us that strains from different origins respond differently to the stress caused by recombinant protein expression—something I had not expected. link.springer.com/article/10.1...
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Thibault Mayor @cellsandprots.bsky.social · 05/05/2026
Very excited to share our preprint on BAG6 and RNF126 in cytosolic protein quality control—from BioID to degron mapping. Along with @rhp-lab.bsky.social, we show this pathway plays a major role in targeting misfolded cytosolic proteins for degradation #proteostasis www.biorxiv.org/content/10.6...
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UBC Biochemistry & Molecular Biology @ubcbiochemistry.bsky.social · 13/11/2025
📢BMBDG Seminar! Join us November 27, 2025 for an in-person presentation by Dr. El Bachir Affar. 📷 November 27, 2025, 2:30 PM, LSC 3 Hope to see you there!
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Thibault Mayor @cellsandprots.bsky.social · 24/05/2025
I survived the 2025 EMBO protein quality control meeting - it was amazing despite a defective projector on day 1, and epileptic crisis on day 2, a black out in day 3, and we all got a shaky wake up call ~6am on day 5 by an earthquake… never a dull moment but most importantly great science
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Thibault Mayor @cellsandprots.bsky.social · 11/05/2025
We ran over 200 eggaggregation experiments for Science Rendezvous - a blast!
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Saccharomyces Genome Database @yeastgenome.bsky.social · 02/04/2025
Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out! meetings.cshl.edu/courses.aspx...
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Thibault Mayor @cellsandprots.bsky.social · 20/03/2025
Here’s a quick throwback to celebrate the last day of winter: curling with the lab!
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Thibault Mayor @cellsandprots.bsky.social · 04/03/2025
Some of you will recognize this - I am done with our CIHR application. Just in time to start teaching a big course section ✌️
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Wyeth Wasserman @wywywa.bsky.social · 27/02/2025
Bioinformatics Job Opportunity Research Associate / Staff Scientist Vancouver Canada Join the Silent Genomes Project to provide an outstanding genetic variation database for Indigenous peoples of Canada to improve rare disease diagnosis tinyurl.com/bm4ptux3 Priority to Canadians Please repost
tinyurl.com
Research Associate
Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Wasserman Laboratory | Department of Medical Genetics | Faculty of Medicine (Wyeth Wasserman) Posting End Date Febr...
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Pablo Nepomnaschy @pablonep.bsky.social · 22/02/2025
Job available for Full Professor Tier 1 Canada Research Chair (CRC) - Indigenous Health and Well-Being at the Faculty of Health Science, Simon Fraser University (RT 🙏🏼 please): www.sfu.ca/vpacademic/a...
sfu.ca
Canada Research Chair - Indigenous Health and Well-Being
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Thibault Mayor @cellsandprots.bsky.social · 07/02/2025
I enjoyed both @cherisirois.bsky.social presentation and conversation about the publishing world and Cell Press today
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Thibault Mayor @cellsandprots.bsky.social · 28/01/2025
With the help of e@UBC our BMB and MSL postdocs organized this great 1/2 day Academia to Industry workshop with a focus on entrepreneurship today
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Thibault Mayor @cellsandprots.bsky.social · 15/01/2025
Even though David Baker's presentation was online, it was rad and inspiring. I really enjoyed today's session on machine learning at the 2025 PepTalk & BioLogic Summit
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Amanda Moehring @flybehaviour.bsky.social · 14/01/2025
Calling early-career colleagues with stories of racism / sexism / microaggressions to share (anonymously or not) for an article someone I know is doing! Please send me a DM asap. They'd need to interview you tomorrow (Tues). It's important these stories are shared, so please do reach out!
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Thibault Mayor @cellsandprots.bsky.social · 10/01/2025
Protein quality control is a tug-of-war between degradation machinery and chaperones that promote folding. Thrilled to see our latest manuscript is now published! 👇 Follow 🧵 for quick summary journals.biologists.com/jcs/article-...
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Marc Johnson (he/him) @evoecolab.bsky.social · 10/12/2024
CONGRATS to @supportourscience.bsky.social, Dr. Kaitlin Kharas, @sarahlaframboise.bsky.social & @cdrobich.bsky.social who were named "Nature's 10", a list of people who shaped science in 2024. #SupportOurScience achieved amazing things. The advocacy continues! www.nature.com/articles/d41...
nature.com
This PhD student helped to win a major pay hike for Canadian researchers
Kaitlin Kharas is part of Nature’s 10, a list of people who shaped science in 2024.
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Cheshire @thatsregrettab1.bsky.social · 16/12/2024
ICYMI: Finland downgrades a bunch of Frontiers and MDPI journals to level 0. julkaisufoorumi.fi/en/news/chan...
julkaisufoorumi.fi
Changes to the classification
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Thibault Mayor @cellsandprots.bsky.social · 10/12/2024
Failures in Science - I just received a negative decision on a grant proposal—my fifth in a row. It’s a though streak but not the first one, and I just wanted to share. short 🧵👇
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Center for Biological Diversity @biologicaldiversity.org · 06/12/2024
Will U.S. government scientists soon face the “muzzling” their Canadian counterparts experienced under right-wing Prime Minister Stephen Harper? David Shiffman spoke to several people whose work was affected by Harper’s regressive policies, and they have advice to help prepare for Trump 2.0. ⬇️
therevelator.org
Advice for U.S. Government Scientists: Lessons Learned From the ‘Muzzling’ of Their Canadian Counterparts • The Revelator
The next four years will be awful for the science and conservation community. By learning from past experiences, we can minimize the damage.
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Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 04/12/2024
ubc.wd10.myworkdayjobs.com/en-US/ubcfac... We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.
ubc.wd10.myworkdayjobs.com
Research Associate
Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Johnson Laboratory | Department of Cellular and Physiological Sciences | Faculty of Medicine (James Johnson) Postin...
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Michael Bertram @michaelgbertram.bsky.social · 03/12/2024
Earlier this year, I received news that fake peer reviews were allegedly being submitted impersonating me and approximately six others I shared my story with Science to, hopefully, reduce the chance of this kind of breach happening again www.science.org/content/arti...
science.org
‘It felt very icky’: This scientist’s name was used to write fake peer reviews
Elsevier retracts dozens of journal articles that were published based on “fictitious” reviews
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Micha Rapé Lab @micharapelab.bsky.social · 03/12/2024
Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI. www.biorxiv.org/content/10.1...
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Thibault Mayor @cellsandprots.bsky.social · 02/12/2024
Congrats to Dane Sands in our lab for his Zymeworks Fellowships Award in Advanced Protein Therapeutics
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Thibault Mayor @cellsandprots.bsky.social · 01/12/2024
Great quick read and a reminder that we first need to admit and accept our ignorance—that's what makes science so fun!
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SFB Targeted Protein Degradation @sfb-tpd-vienna.bsky.social · 29/11/2024
SAVE THE DATE 🗓️Ubiquitin & Friends Symposium: 8-9 May 2025 in Vienna! Registration will open🔜 Keep an eye out for the announcement 👀 ✨guest speaker lineup👇🧵 +talks from abstracts! Great chance for #ECRs to meet with peers & experts in a friendly setting! 🔗 www.protein-degradation.org/symposium/
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Thibault Mayor @cellsandprots.bsky.social · 29/11/2024
This is real cool study showing how ubiquitin can recruit and activate a protease to eliminate a (DNA cross linked) protein … independently of the proteasome
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Xin Tang @xintang.bsky.social · 28/11/2024
🚀 Excited to announce that our Lab @UBC is recruiting! 🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces. 🏔️ Vancouver awaits! 👉 tanglab.msl.ubc.ca 📧 xin.tang@msl.ubc.ca
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Thibault Mayor @cellsandprots.bsky.social · 27/11/2024
I love CAT tails (how cool is to have an RNA-independent pathway to synthesize polypeptides at the ribosome). Check out our preview article on a recent study from the Young-Jun Choe's lab written by @shriyakamat.bsky.social www.cell.com/molecular-ce...
cell.com
Lost in translation: Threonine dictates aggregation of CAT tails
In this issue of Molecular Cell, Chang et al. elaborate on the mechanisms by which CAT tail aggregation is mediated through threonine residues and how it contributes to the perturbation of proteostasi...
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Thibault Mayor @cellsandprots.bsky.social · 25/11/2024
agree!! I can only remember 1/2 of the acronyms on a good day, so when a sentence uses several of them, it simply become too cryptic I use a bold font each time I introduce an acronym to help distracted readers
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Thibault Mayor @cellsandprots.bsky.social · 25/11/2024
I read that article last spring and I highly recommend it - even for non NIH applications!!!
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CNPN @cnpn-org.bsky.social · 22/11/2024
Thanks to CNPN 2024 organizers, @philipplange.bsky.social and Mari De Marco, great sponsors, and all participants who made this conference happen🙌
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Thibault Mayor @cellsandprots.bsky.social · 21/11/2024
Thanks for doing this!
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Thibault Mayor @cellsandprots.bsky.social · 21/11/2024
Our lab sells them for 1/2 of the price in case you are interested
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Thibault Mayor @cellsandprots.bsky.social · 19/11/2024
Shriya from our lab presented our work on temporal BioID at the @cnpn-org.bsky.social meeting today It’s a great feeling when trainees do a better job at presenting their work than we could have done 🤩
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Thibault Mayor @cellsandprots.bsky.social · 19/11/2024
Sahil presenting some of his bioID work at the 2024 CNPN go #proteomics !
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Thibault Mayor @cellsandprots.bsky.social · 18/11/2024
Ryan from our lab presenting his work @cnpn looking at yeast strains capable of producing more recombinant proteins. When we started doing #proteomics we actually found quite important differences between these strains More here www.biorxiv.org/content/10.1...
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Thibault Mayor @cellsandprots.bsky.social · 18/11/2024
Snowflakes & Proteomics: the 2024 CNPN Fairmont fairytale… once upon a time there was a tiny single cell (Ljijana Pasa-Tolic), a mutated proteome (Matthew Berg from the Villen lab) and a nasty protease (Olivier Julien)…
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Thibault Mayor @cellsandprots.bsky.social · 16/11/2024
Team work: making our new batch of competent cells (2.5 x 10^8) for next year of cloning
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