Thibault Mayor @cellsandprots.bsky.social · 02/09/2026Doing proteomics on different yeast biofactories showed us that strains from different origins respond differently to the stress caused by recombinant protein expression—something I had not expected. link.springer.com/article/10.1... 130
Thibault Mayor @cellsandprots.bsky.social · 05/05/2026Very excited to share our preprint on BAG6 and RNF126 in cytosolic protein quality control—from BioID to degron mapping. Along with @rhp-lab.bsky.social, we show this pathway plays a major role in targeting misfolded cytosolic proteins for degradation #proteostasis www.biorxiv.org/content/10.6... 2112
Reposted by Thibault MayorUBC Biochemistry & Molecular Biology @ubcbiochemistry.bsky.social · 13/11/2025📢BMBDG Seminar! Join us November 27, 2025 for an in-person presentation by Dr. El Bachir Affar. 📷 November 27, 2025, 2:30 PM, LSC 3 Hope to see you there! 013
Thibault Mayor @cellsandprots.bsky.social · 24/05/2025I survived the 2025 EMBO protein quality control meeting - it was amazing despite a defective projector on day 1, and epileptic crisis on day 2, a black out in day 3, and we all got a shaky wake up call ~6am on day 5 by an earthquake… never a dull moment but most importantly great science 1131
Thibault Mayor @cellsandprots.bsky.social · 11/05/2025We ran over 200 eggaggregation experiments for Science Rendezvous - a blast! 050
Reposted by Thibault MayorSaccharomyces Genome Database @yeastgenome.bsky.social · 02/04/2025Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out! meetings.cshl.edu/courses.aspx... 1811
Thibault Mayor @cellsandprots.bsky.social · 20/03/2025Here’s a quick throwback to celebrate the last day of winter: curling with the lab! 060
Thibault Mayor @cellsandprots.bsky.social · 04/03/2025Some of you will recognize this - I am done with our CIHR application. Just in time to start teaching a big course section ✌️ 090
Reposted by Thibault MayorWyeth Wasserman @wywywa.bsky.social · 27/02/2025Bioinformatics Job Opportunity Research Associate / Staff Scientist Vancouver Canada Join the Silent Genomes Project to provide an outstanding genetic variation database for Indigenous peoples of Canada to improve rare disease diagnosis tinyurl.com/bm4ptux3 Priority to Canadians Please reposttinyurl.comResearch AssociateAcademic Job Category Faculty Non Bargaining Job Title Research Associate Department Wasserman Laboratory | Department of Medical Genetics | Faculty of Medicine (Wyeth Wasserman) Posting End Date Febr... 02830
Reposted by Thibault MayorPablo Nepomnaschy @pablonep.bsky.social · 22/02/2025Job available for Full Professor Tier 1 Canada Research Chair (CRC) - Indigenous Health and Well-Being at the Faculty of Health Science, Simon Fraser University (RT 🙏🏼 please): www.sfu.ca/vpacademic/a...sfu.caCanada Research Chair - Indigenous Health and Well-Being 06579
Thibault Mayor @cellsandprots.bsky.social · 07/02/2025I enjoyed both @cherisirois.bsky.social presentation and conversation about the publishing world and Cell Press today 061
Thibault Mayor @cellsandprots.bsky.social · 28/01/2025With the help of e@UBC our BMB and MSL postdocs organized this great 1/2 day Academia to Industry workshop with a focus on entrepreneurship today 020
Thibault Mayor @cellsandprots.bsky.social · 15/01/2025Even though David Baker's presentation was online, it was rad and inspiring. I really enjoyed today's session on machine learning at the 2025 PepTalk & BioLogic Summit 000
Reposted by Thibault MayorAmanda Moehring @flybehaviour.bsky.social · 14/01/2025Calling early-career colleagues with stories of racism / sexism / microaggressions to share (anonymously or not) for an article someone I know is doing! Please send me a DM asap. They'd need to interview you tomorrow (Tues). It's important these stories are shared, so please do reach out! 135
Thibault Mayor @cellsandprots.bsky.social · 10/01/2025Protein quality control is a tug-of-war between degradation machinery and chaperones that promote folding. Thrilled to see our latest manuscript is now published! 👇 Follow 🧵 for quick summary journals.biologists.com/jcs/article-... 13815
Reposted by Thibault MayorMarc Johnson (he/him) @evoecolab.bsky.social · 10/12/2024CONGRATS to @supportourscience.bsky.social, Dr. Kaitlin Kharas, @sarahlaframboise.bsky.social & @cdrobich.bsky.social who were named "Nature's 10", a list of people who shaped science in 2024. #SupportOurScience achieved amazing things. The advocacy continues! www.nature.com/articles/d41...nature.comThis PhD student helped to win a major pay hike for Canadian researchersKaitlin Kharas is part of Nature’s 10, a list of people who shaped science in 2024. 1209
Reposted by Thibault MayorCheshire @thatsregrettab1.bsky.social · 16/12/2024ICYMI: Finland downgrades a bunch of Frontiers and MDPI journals to level 0. julkaisufoorumi.fi/en/news/chan...julkaisufoorumi.fiChanges to the classification 23717
Thibault Mayor @cellsandprots.bsky.social · 10/12/2024Failures in Science - I just received a negative decision on a grant proposal—my fifth in a row. It’s a though streak but not the first one, and I just wanted to share. short 🧵👇 220
Reposted by Thibault MayorCenter for Biological Diversity @biologicaldiversity.org · 06/12/2024 Will U.S. government scientists soon face the “muzzling” their Canadian counterparts experienced under right-wing Prime Minister Stephen Harper? David Shiffman spoke to several people whose work was affected by Harper’s regressive policies, and they have advice to help prepare for Trump 2.0. ⬇️therevelator.orgAdvice for U.S. Government Scientists: Lessons Learned From the ‘Muzzling’ of Their Canadian Counterparts • The RevelatorThe next four years will be awful for the science and conservation community. By learning from past experiences, we can minimize the damage. 714996
Reposted by Thibault MayorJim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 04/12/2024ubc.wd10.myworkdayjobs.com/en-US/ubcfac... We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.ubc.wd10.myworkdayjobs.comResearch AssociateAcademic Job Category Faculty Non Bargaining Job Title Research Associate Department Johnson Laboratory | Department of Cellular and Physiological Sciences | Faculty of Medicine (James Johnson) Postin... 169
Reposted by Thibault MayorMichael Bertram @michaelgbertram.bsky.social · 03/12/2024Earlier this year, I received news that fake peer reviews were allegedly being submitted impersonating me and approximately six others I shared my story with Science to, hopefully, reduce the chance of this kind of breach happening again www.science.org/content/arti...science.org‘It felt very icky’: This scientist’s name was used to write fake peer reviewsElsevier retracts dozens of journal articles that were published based on “fictitious” reviews 26436195
Reposted by Thibault MayorMicha Rapé Lab @micharapelab.bsky.social · 03/12/2024Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI. www.biorxiv.org/content/10.1... 811635
Thibault Mayor @cellsandprots.bsky.social · 02/12/2024Congrats to Dane Sands in our lab for his Zymeworks Fellowships Award in Advanced Protein Therapeutics 030
Thibault Mayor @cellsandprots.bsky.social · 01/12/2024Great quick read and a reminder that we first need to admit and accept our ignorance—that's what makes science so fun! 094
Reposted by Thibault MayorSFB Targeted Protein Degradation @sfb-tpd-vienna.bsky.social · 29/11/2024SAVE THE DATE 🗓️Ubiquitin & Friends Symposium: 8-9 May 2025 in Vienna! Registration will open🔜 Keep an eye out for the announcement 👀 ✨guest speaker lineup👇🧵 +talks from abstracts! Great chance for #ECRs to meet with peers & experts in a friendly setting! 🔗 www.protein-degradation.org/symposium/ 15928
Thibault Mayor @cellsandprots.bsky.social · 29/11/2024This is real cool study showing how ubiquitin can recruit and activate a protease to eliminate a (DNA cross linked) protein … independently of the proteasome 031
Reposted by Thibault MayorXin Tang @xintang.bsky.social · 28/11/2024🚀 Excited to announce that our Lab @UBC is recruiting! 🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces. 🏔️ Vancouver awaits! 👉 tanglab.msl.ubc.ca 📧 xin.tang@msl.ubc.ca 0104
Thibault Mayor @cellsandprots.bsky.social · 27/11/2024I love CAT tails (how cool is to have an RNA-independent pathway to synthesize polypeptides at the ribosome). Check out our preview article on a recent study from the Young-Jun Choe's lab written by @shriyakamat.bsky.social www.cell.com/molecular-ce...cell.comLost in translation: Threonine dictates aggregation of CAT tailsIn this issue of Molecular Cell, Chang et al. elaborate on the mechanisms by which CAT tail aggregation is mediated through threonine residues and how it contributes to the perturbation of proteostasi... 1165
Thibault Mayor @cellsandprots.bsky.social · 25/11/2024agree!! I can only remember 1/2 of the acronyms on a good day, so when a sentence uses several of them, it simply become too cryptic I use a bold font each time I introduce an acronym to help distracted readers 100
Thibault Mayor @cellsandprots.bsky.social · 25/11/2024I read that article last spring and I highly recommend it - even for non NIH applications!!! 040
Reposted by Thibault MayorCNPN @cnpn-org.bsky.social · 22/11/2024Thanks to CNPN 2024 organizers, @philipplange.bsky.social and Mari De Marco, great sponsors, and all participants who made this conference happen🙌 192
Thibault Mayor @cellsandprots.bsky.social · 21/11/2024Our lab sells them for 1/2 of the price in case you are interested 000
Thibault Mayor @cellsandprots.bsky.social · 19/11/2024Shriya from our lab presented our work on temporal BioID at the @cnpn-org.bsky.social meeting today It’s a great feeling when trainees do a better job at presenting their work than we could have done 🤩 0132
Thibault Mayor @cellsandprots.bsky.social · 19/11/2024Sahil presenting some of his bioID work at the 2024 CNPN go #proteomics ! 020
Thibault Mayor @cellsandprots.bsky.social · 18/11/2024Ryan from our lab presenting his work @cnpn looking at yeast strains capable of producing more recombinant proteins. When we started doing #proteomics we actually found quite important differences between these strains More here www.biorxiv.org/content/10.1... 041
Thibault Mayor @cellsandprots.bsky.social · 18/11/2024Snowflakes & Proteomics: the 2024 CNPN Fairmont fairytale… once upon a time there was a tiny single cell (Ljijana Pasa-Tolic), a mutated proteome (Matthew Berg from the Villen lab) and a nasty protease (Olivier Julien)… 0102
Thibault Mayor @cellsandprots.bsky.social · 16/11/2024Team work: making our new batch of competent cells (2.5 x 10^8) for next year of cloning 020