Animals fluctuate between high and low performance states during decision-making. Bandi et al. demonstrate that parietal cortex is causally required for maintaining high-performance states during auditory localization. Parietal cortex population activity distinguishes performance states and exhibits enhanced correlational structure only during the high-performance state, unlike primary auditory cortex.

Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasti...

Behavioural experiments to study decision-making in response to context-dependent accumulation of evidence provide testable models that are consistent with the heterogeneity in neural signatures among...

Carl Olson, Professor of the Neuroscience Institute at Carnegie Mellon University, passed away on November 23, 2024. Carl was an internationally renowned neuroscientist who provided important insights...

The structure of local circuits is highly conserved across the cortex, yet the spatial and temporal properties of population activity differ fundamentally in sensory-level and association-level areas....

The Office for Civil Rights today sent letters to 60 institutions of higher education warning them of potential enforcement actions if they do not fulfill their obligations under Title VI of the Civil...

Behavioural-state-dependent pyramidal neurons have a distinct pattern of long-range glutamatergic inputs, with a larger proportion of thalamic versus motor cortex inputs compared with non-behavio...

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