Scientists have unearthed a rare class of ultra-potent antibodies derived from llamas that can neutralize a vast array of coronaviruses—including SARS-CoV-1 and multiple forms of SARS-CoV-2, both old ...

Lipids play a critical role in the physiology, life cycle, and pathogenicity of mycobacteria. They largely participate in host–pathogen interactions and fulfill important functions ranging from cell w...

The constant emergence of drug-resistant mycobacteria, together with the lack of new antibiotics entering the market, has become a global public health problem that threatens the effective treatment o...

Research Associate Genetic and functional analysis of Gram positive secretion systems and substrates

Research Associate - Biochemical and structural analysis of bacterial protein toxins

This study sheds light into the complex process of intracellular lipid accumulation and storage in the survival and persistence of pathogenic mycobacteria, which is of clinical relevance. By identifying the proteins involved in the formation of ...

Background Mycobacterium abscessus is an emerging pathogen causing severe pulmonary infections, particularly in individuals with underlying conditions, such as cystic fibrosis or chronic obstructive p...

Salicylic acid (SA), its two iodinated analogues 5ISA and 3,5diISA, as well as the anti-inflammatory drug aspirin (ASP), are anti-TB drugs that disrupt the intrabacterial pH homeostasis of Mycobacter...

Background Mycobacterium abscessus is an emerging pathogen causing severe pulmonary infections, particularly in individuals with underlying conditions, such as cystic fibrosis or chronic obstructive p...

The glycolytic pathway is required for maximum IL-1β production by macrophages infected with live distinct M. tuberculosis isolates, but mitochondria metab