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Preprint - Experimental hypoxia to probe neuro-metabolic and vascular dysregulation in ME/CFS: a multimodal proof-of-concept MRI study, 2026, Bader et al.
Now, when exposed to the simulated hypoxic conditions, the Lac/tCr ratio increases less than healthy controls, this could mean there is a lesser capacity for additional compensatory glycolysis to be g...
![Central origin of fatigability in Myalgic encephalomyelitis/chronic fatigue syndrome revealed by multimodal neuroimaging — Bedard et al
"Our most novel results relate to the lack of neuromuscular adaptation in ME/CFS compared to the [Healthy Volunteers]." "ME/CFS did not change their muscular and brain activity as measured via DI, EEG, BOLD, and CMC, and as a result, they demonstrated fatigue earlier than HV"
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