The Sinha lab studies key aspects of protein synthesis and translational control in healthy and diseased states. We study the multifaceted roles of ribosomes as critical sensors of cellular stress.

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Nature Communications - Here, the authors present a method to rapidly isolate actively translating ribosomes in a time- and cost-effective manner using poly-lysine. The method is compatible with a...

After a quarter of a century, the website remains an essential tool for navigating the genome and understanding its structure, function and clinical impact.

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Intersex people are speaking out in the face of the administration’s efforts to define sex as a biological binary.

Frustrated that there seemed to be no large-scale pro-science movement coalescing, a graduate student took matters into her own hands

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Ever wonder why people label octopuses as "aliens"? It's not because they hitched a ride on a meteor from outer space. Nope, these eight-armed geniuses earned their intergalactic reputation by doing s...

An email obtained by NPR says NIH employees are subject to a travel freeze and offers of employment are being rescinded. Scientists worry about disruptions to critical research.

Inhibitors of protein synthesis, including anisomycin, homoharringtonine, and other natural products bind in the peptidyl-transferase center (PTC) of the eukaryotic ribosome to inhibit translation. Re...