iiinova — where your digital self keeps evolving

Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 27/09/2026

Time to boycott @mlb.com (easy for me since I don’t watch baseball). Our national parks are not for sale!

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doxy-cycling.bsky.social @doxy-cycling.bsky.social · 08/09/2026

No! 🤬

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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 05/09/2026

“Totalitarianism demands, in fact, the continuous alteration of the past, and in the long run probably demands a disbelief in the very existence of objective truth” —George Orwell, from Orwell on Truth

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 26/08/2026

Everything you need to know about why Children’s Health Defense needs to be buried under so much legal and financial burdens that they cease to exist at all.

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 17/08/2026

AI companies destroying books is despicable, and I wish was a criminal act.

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 17/08/2026

Please don’t waste time and money sending a test that tells you someone has bacteria in their urine. We know they do; it’s not sterile! #IDSky

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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 11/08/2026

Measles cases in the US just hit a 35-year high This is an illness that can be eliminated. Eliminated. And the response from RFK Jr & the 2 physicians with him yesterday (Drs Bhattacharya & Overton) was to issue guidance that will LOWER MMR vaccination rates It's what anti-vaxx activists would do

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Michael Osterholm, PhD, MPH @mtosterholm.bsky.social · 10/08/2026

In response to today’s White House Executive Order (EO) on vaccines, parents should continue to rely on evidence-based immunization recommendations developed by experts. Today's EO does not change the scientific evidence supporting childhood immunization. That data has been built over decades.

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Gillian Branstetter @gbbranstetter.bsky.social · 31/07/2026

El Sayed: "When it comes to trans rights, this is the right to get the health care that you need...It’s the right not to be discriminated against by your government because of who you are. Because what tends to happen is they come for theirs, then they come for yours"

The idea that we can assent to the taking away of anybody’s rights, and think that somehow the government won’t come for all of our rights, is itself the problem. And, look, I don’t need people to understand how they use their rights. I just need people to agree that the government shouldn’t be able to take any of our rights. I put my face on the ground thirty-four times a day, David. Most people don’t understand why I do it. I don’t need them to understand. I just want to have the right to do it. And when people decide that they want to take away my right to do that, I’ve got a problem.

Now, I hope that everybody’s going to show up and say, No, no, no. You can’t stop that person or that community from reflecting and praying as they choose. Similarly, when it comes to trans rights, this is the right to get the health care that you need. That’s really what it comes down to. It’s the right to be who you are. It’s the right not to be discriminated against by your government because of who you are. Because what tends to happen is they come for theirs, then they come for yours, then they come for theirs. And at some point you live in a society where rights are negotiable, and that is not the America I was born in. It’s not the America I know and love. It’s not the America I’m going to allow somebody like Donald Trump to give us.

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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 27/07/2026

🔥🔥Just published 🔥🔥 IDSA AMR Guidance 2026 IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections 🔺ESBL , AmpC Enterobacterales 🔺CRE 🔺DTR P. aeruginosa 🔺CRAB 🔺Stenotrophomonas maltophilia #idsky www.idsociety.org/practice-gui...

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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 24/07/2026

Ah yes, when it comes to making a decision about whether or not to approve an experimental unproven drug, it is CRUCIAL to ensure that “sellers” of the product—the ones with the most extreme financial conflicts of interests—get to decide! MAHA is just grift & blatant corruption

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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 23/07/2026

Jay Bhattacharya is head of the CDC, so this utter BS tracks….

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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 21/07/2026

Evidence from Mexico that Ceftriaxone is an effective alternative to IV penicillin for neurosyphilis in PLWH Prospective data would be so helpful for this, as we need better alternatives (ideally something PO) #IDSky academic.oup.com/ofid/article...

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Society of Infectious Diseases Pharmacists - SIDP @sidpharm.bsky.social · 16/07/2026

🧐Did you know most patients with a labeled penicillin allergy can tolerate the drug? Not to mention other beta lactams! Proactively de-labeling and providing education is crucial for patient care and antimicrobial stewardship 🥳 #stewardship #AncefForAll

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Andy Conway Morris @andymoz78.bsky.social · 12/07/2026

Vaccines work, folks. Measles is an entirely preventable disease, it has no animal reservoir

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Society of Infectious Diseases Pharmacists - SIDP @sidpharm.bsky.social · 06/07/2026

New to ID? Want to network and hear from experts in the field? Check out our Antimicrobial Stewardship Certificate Program! To see the program description and register, please visit the link in our bio.

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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 17/06/2026

🔥Just published 🔥NEJM SNAP RCT In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky www.nejm.org/doi/full/10....

nejm.org

Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia | NEJM

Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus ...

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 11/06/2026

Great paper for all the cephalexin/cefadroxil users out there! #IDSky

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Patrick Ching @patrickching.bsky.social · 12/05/2026

Adding tobramycin powder to vancomycin powder during surgery for high-risk periarticular tibial fractures does NOT offer extra protection against deep surgical site infection compared w vancomycin alone #IDSky #MedSky jamanetwork.com/journals/jama/fullarticle/2847582

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University of Minnesota Infectious Diseases @umn-idim.bsky.social · 05/05/2026

🚨 New research alert! For early postoperative spinal implant infections (PSII) managed with debridement and implant retention, is longer antibiotic therapy always better? Our team, alongside 9 other academic centers, evaluated 499 patients to find out. #IDSky

academic.oup.com

Antibiotic Duration after Debridement and Implant Retention for Early Postoperative Spinal Implant Infections: A Multicenter Cohort Study

In this multicenter retrospective cohort of 499 patients with early postoperative spinal implant infection managed by debridement and implant retention, ex

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Steven Tong @steventong.bsky.social · 06/05/2026

We looked at empiric B-lactam antibiotics in MRSA bacteraemia and BC persistence and AKI, using CAMERA2 dataset. Groups: none, early (only empiric B-lactam), late (only after trial enrolment), throughout (empiric and after enrolment). #IDSky www.clinicalmicrobiologyandinfection.org/article/S119...

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jamelle @jamellebouie.net · 30/04/2026

as long as john roberts has his majority, there is simply no pro democracy reform that will survive the supreme court. none.

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 28/04/2026

Film you've watched more than six times with gif. hard mode: no star wars, star trek, lotr, dc, marvel, disney, pixar, dreamworks, spielberg, cameron, wachowskis, or ghibli

media.tenor.com

ALT:

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Ilan Schwartz @germhuntermd.bsky.social · 23/04/2026

Spinal Epidural Abscess Aaron Tande and colleagues Review in @nejm.org #IDSky www.nejm.org/doi/full/10....

Diagram of relevant anatomy along with MRI findings in spinal abscess

Microbiology of SEA.

Table 2. Pathogens Associated with Spinal Epidural Abscess.*
Pathogen
Infections Attributable to Pathogen or Pathogen Group

Methicillin-susceptible Staphylococcus aureus
40%
Methicillin-resistant S. aureus
18%
Coagulase-negative staphylococcus species
5%
Streptococcus or enterococcus species
10%
Aerobic gram-negative bacilli
4%
Other pathogens
6%
Polymicrobial infections
2%
No growth or unknown
14%
* Shown are data from 2282 patients included in observational studies.511

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 23/04/2026

Wow, I wish our mindset here in the US was to discharge patients on PO ABX as option #1 and IV only if necessary. #IDSky

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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 23/04/2026

NGL the last few days were rough for folks working in public health—RFK Jr’s horrific lies, his extraordinarily vile eugenics, his blaming infectious diseases on immigrants, his refusal to take any responsibility for the measles crisis or its control & the appointment of a tobacco executive at CDC 🫣

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 22/04/2026

This administration is full of such despicable people. #VaccinesWork

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Gregg Gonsalves @gregggonsalves.bsky.social · 21/04/2026

~53,000 military personnel died in combat in WW1. ~45,000 other soldiers died from the flu. #PeteHegseth may be ignorant of history, careless about the lives of those in uniform, but the army remembers. www.army.mil/article/2104...

army.mil

Worldwide flu outbreak killed 45,000 American Soldiers during World War I

In September 1918 there were two killers in the world. World War I, which would claim 20 million lives by its end, and the flu pandemic known as the Spanish Flu, is estimated to have killed between at...

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 21/04/2026

I agree. Definitely not going back to the Other Place!

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Clinical Infectious Diseases @cidjournal.bsky.social · 08/04/2026

Evaluation of the impact of universal mupirocin decolonization in intensive care units on the utility of MRSA PCR nasal swab testing ✅ Just Accepted 🔗 bit.ly/4bWBN9b

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Kathleen Bachynski @bachynski.bsky.social · 31/03/2026

I showed this graph in class yesterday on how measles cases in the United States plummeted dramatically after the vaccine was licensed in 1963. It’s not subtle and I could not resist observing: “This stunning design in measles cases was not thanks to vitamin A. It was not due to beef tallow.”

A graph titled “the public health success of the measles vaccine” that shows the number of measles cases in the United States plummeting after the vaccine was introduced in 1963

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josh farkas 💊 @pulmcrit.bsky.social · 26/03/2026

missing sepsis - bad misdiagnosing another catastrophe as “sepsis” - also bad it almost makes me think that maybe we should specially train people how to identify and differentiate these disease processes and provide personalized care 🤔

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Sitting on a corn flake @grrlscientist.bsky.social · 26/03/2026

Never in recorded history has a four-year-old found his father’s loaded book and accidentally killed his younger sister with it. BUT WE BAN BOOKS NOT GUNS #guns #violence #BookBans #NaziAmeriKKKa #fascism

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Dimitri Drekonja, MD, MS @dimitridrekonja.bsky.social · 21/03/2026

I’m old enough to remember people being fired for saying this about Charlie Kirk 🤷🏻‍♂️

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AnniePdD @anniepdd.bsky.social · 20/03/2026

@jakescottmd.bsky.social connects the dots perfectly in this must-read @cidrap.bsky.social op-ed. It's hard to focus on any single issue with this ongoing barrage of insanity and illegality, but what's happening at HHS/CDC needs to stay on everyone's short list of important issues.

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Clinical Infectious Diseases @cidjournal.bsky.social · 15/03/2026

IDSA 2025 Guidelines on the use of vaccines for the prevention of seasonal COVID-19 infections in immunocompromised patients ✅ Just Accepted 🔗 bit.ly/47FAtok

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 14/03/2026

My favorite is when they’re on dapto + ceftaroline, but the ICU is convinced the patient has a new VAP and adds Zosyn 😭

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 06/03/2026

Really disappointed in the ATS’ stubbornness and doubling down on a bad rec that they keep trying to justify with weak reasoning.

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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 01/03/2026

New PJI study in @ofidjournal.bsky.social: Largest restrospective study to date of doxycycline use for PJI treatment with encouraging results All doxycycline use was in combination though, primarily rifampin. Limited to Staph, Coryne, & Cuti #IDSky #OrthoID academic.oup.com/ofid/advance...

academic.oup.com

Effectiveness of Doxycycline in Combination with Other Antibiotics for Gram-Positive Periprosthetic Joint Infections: a Causal Inference Study

AbstractObjectives. Doxycycline is occasionally used as step-down therapy in periprosthetic joint infections (PJI), but evidence supporting its efficacy is

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Ben Ereshefsky, PharmD @brainofbpharm.bsky.social · 28/02/2026

“When the rich wage war, it’s the poor who die.” -Sartre

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Society of Infectious Diseases Pharmacists - SIDP @sidpharm.bsky.social · 25/02/2026

🥳SIDP is turning 35 this year!🥳 Let’s get in that celebratory birthday mood by looking back at some of the things going on when SIDP was founded 😱⏰ Follow along because we’ll be keeping the party going all year long!

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Ilan Schwartz @germhuntermd.bsky.social · 13/02/2026

Mucormycosis Review in @nejm.org by Dimitrios Kontoyiannis and Tom Walsh www.nejm.org/doi/10.1056/... #IDSky #TxID #MedMycoSky @msgerc.bsky.social

Pathogenesis of Mucormycosis, Host Defenses, and Potential Future Therapeutic Targets.
Mucorales sporangiospores released into the air from sporangia are inhaled, and the sporangiospore coat protein CotH3 binds to GRP78 on the pseudostratified columnar epithelial cells of the upper resp tract, where the sporangiospores may germinate into hyphae to invade nasal airways and sinuses (Panel A). Sporangiospores, by means of another coat adhesin (CotH7), also bind to epidermal growth factor receptor (EGFR) and integrin α3β1 receptor on pulmonary alveolar epithelial cells of the lower respiratory tract, which triggers a downstream transcriptional response involving cytokines (interleukin-6 and interleukin-8), chemokines (CCL2 and CCL5), and intercellular adhesion molecule 1 (ICAM-1). Hyphal invasion also triggers production of hypoxia-inducible factor 1α (HIF1α) and release of proinflammatory cytokines. In wound-related mucormycosis, traumatic inoculation of fungal elements (found on the surfaces of rocks, wood, glass, and metal) into damaged tissue allows for the development of infection in a host with immune paralysis due to trauma. The release of endogenous host-derived molecules known as damage-associated molecular patterns (DAMPs) reduces phagocytosis, impairs chemotaxis, and induces immune paralysis. Mucoricin released by the invading hyphae induces death of immune and endothelial cells, which results in tissue necrosis and accelerates endovascular thrombosis, ischemia, and infarction (Panel B). PMNs and monocytes recognize early germinated sporangiospores by pattern recognition receptors (e.g., TLR2) that detect mucorales-associated molecular patterns (e.g., 1,3-βD-glucans exposed on hyphal structures). Intrinsic host colony-stimulating factors such as granulocyte–macrophage colony-stimulating factor (GM-CSF) and IFN-γ further contribute to augmentation of innate host defenses against the invading hyphae, which in turn dampen immune responses. Factors in the tissue …

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rahaeli @rahaeli.bsky.social · 10/02/2026

I genuinely cannot believe the degree to which we are pissing away this generational breakthrough, even given the fuckmuppets who are involved www.nbcnews.com/health/healt...

nbcnews.com

FDA declines to review Moderna's mRNA flu shot

Under Health Secretary Robert F. Kennedy Jr., the Food and Drug Administration has taken an aggressive stance against mRNA technology.

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Ambassador Ken Fairfax (ret) @portlandken.bsky.social · 27/01/2026

Today's front page on @lemonde.fr

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NBC News @nbcnews.com · 25/01/2026

DHS has shot 12 people during immigration enforcement operations since September:

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