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Bianca Introini

@bianca-introini.bsky.social
137 followers 214 following 6 posts

Structural Biologist | Ion channels and membrane proteins enthusiast | Curious to see what’s inside cells nuclei | Cryo-EM and Cryo-ET | Post doc at Max Planck Institute of Biophysics in @becklab.bsky.social

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Reposted by Bianca Introini
Katharina Geißler @kgeissler.bsky.social · 21/04/2026
Out now in Nature Communications! We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky www.nature.com/articles/s41...
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Reposted by Bianca Introini
Max Planck Institute of Biophysics @mpibp.bsky.social · 20/04/2026
That’s a wrap on our @embo.org #cryoFIB & #cryoET course! It was an incredible week of hands-on learning, collaboration, and shared expertise, made possible by dedicated organizers, incredible trainers, and an engaged group of participants.
A large diverse group of people waving and smiling at the camera in front of scientific posters displayed on a wall.
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Reposted by Bianca Introini
Max Planck Institute of Biophysics @mpibp.bsky.social · 17/04/2026
We are having a very hands-on week at the @embo.org #cryoFIB & #cryoET course 🔬 Our participants are learning about sample vitrification, lamella milling, FLM, lift-out, data acquisition and more! We are learning by doing, troubleshooting, and sharing expertise across labs. 🧪
Three female researchers discuss data displayed on dual monitors in a microscopy workspace with keyboards, mouse, and electronic equipment on the desk.Two female researchers working at a computer displaying a 3D scientific visualization on a large curved monitor in a modern office.Two young researchers examining an object with tweezers in a lab setting near a sink and hygiene supplies.Group of participants in a lab setting reviewing microscopy images on computer screens and looking at printed diagrams during a practical course.
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Bianca Introini @bianca-introini.bsky.social · 14/07/2025
Great work by @tzujingyang.bsky.social and @melaniemcdowell.bsky.social!!
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Reposted by Bianca Introini
RSPB @rspb.bsky.social · 08/05/2025
Happy 99th birthday to the man who gave voice to the wild. 🎉 Sir David Attenborough, thank you for a lifetime dedicated to the natural world, and for sharing its story with wisdom, wonder, and grace. You've inspired generations to fall in love with nature.
This photograph captures Sir David Attenborough seated outdoors on the rugged terrain of Skomer Island. Behind him, the ocean and coastal cliffs form a scenic backdrop under a clear sky. Sir David, dressed in a khaki jacket and light trousers, looks towards the camera with a gentle expression, exuding a sense of warmth, calm, and wisdom. Around him, puffins can be seen flying and perched on the rocky ground, illuminated in rays of golden sunlight as the sun sets behind the cliffs.
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Vanessa Linke @massspecvanili.bsky.social · 18/04/2025
Super excited to share this as my first post with the 🦋 world! In my first co-correspondent article, we (@Mayra Borrero @Agnieszka Chacińska @IMOL Institute) look at the roles of lipids in mitochondrial protein import complexes (spoiler: there are plenty!) &call for methods (spoiler: there are few!)
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Reposted by Bianca Introini
Jan Philipp Kreysing @jpkreysing.bsky.social · 11/04/2025
New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇
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RCSB Protein Data Bank @rcsbpdb.bsky.social · 10/03/2025
After the start of the AIDS epidemic, scientists revealed the atomic structures of the molecules in HIV, helping to design treatments Explore how PDB structures help our understanding of HIV at PDB-101 #CROI2025 pdb101.rcsb.org/brow... Images are free for use
pdb101.rcsb.org
PDB101: Browse: HIV and AIDS
PDB-101: Training, Outreach, and Education portal of RCSB PDB
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Reposted by Bianca Introini
Mitosis Lab @mitosislab.bsky.social · 04/03/2025
Zhi Yang Tan & @shujuncai.bsky.social's comparative study of G0 (quiescent) and interphase fission yeast cells is out in @jcellsci.bsky.social doi.org/10.1242/jcs.263654. This study combines multiple cell-biological analyses with in situ cryo-ET. Raw data: www.ebi.ac.uk/empiar/EMPIAR-10339
DIC and cryo-ET images of G1 and G0 fission yeast cells.
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Reposted by Bianca Introini
Jana Kroll @janakroll.bsky.social · 12/02/2025
Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" www.biorxiv.org/content/10.1... We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️
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Rita Strack @ritastrack.bsky.social · 12/02/2025
It turns out this works well for improving segmentation, and Cellpose3 offers a general solution for many segmentation tasks. Please see the full paper for all the details. www.nature.com/articles/s41...
nature.com
Cellpose3: one-click image restoration for improved cellular segmentation - Nature Methods
Cellpose3 employs deep-learning-based approaches for image restoration to improve cellular segmentation and shows strong generalized performance even on images degraded by noise, blurring or undersamp...
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Reposted by Bianca Introini
Constantin Pape @cppape.bsky.social · 12/02/2025
After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...
Improvements in LM (top) and EM (bottom) of our micro-sam model (finetuned) compared to the default SAM model.
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Pablo J. Sáez @pjsaez.bsky.social · 10/02/2025
Hot from the press for #CellMigration + #Nucleus aficionados Karling @helenweavers.bsky.social lab show *in vivo* how immune cell adapt quickly to confined microenvironments during motility. Live-cell imaging, image analysis, #Drosophila ! Full @emboreports.org www.embopress.org/doi/full/10....
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Bianca Introini @bianca-introini.bsky.social · 07/02/2025
These days at EMBL in Heidelberg for the EMBO Workshop “In situ structural biology: expanding the toolbox for structural cell biology” were amazing! I showed my work on the tetrameric serotonin receptor: www.embopress.org/doi/full/10.... #EMBOinsitu
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Reposted by Bianca Introini
Pablo J. Sáez @pjsaez.bsky.social · 06/02/2025
#CellMigration happens all the time in our bodies. This may (or not) rely on adhesion molecules #Cancer cells switch strategies during metastasis to invade other tissues Naomi Wee (naomiwee.com) did this neat movie to explain it: www.youtube.com/watch?v=D9aD... #SciSky 🧪🔬 @cellcommlab.bsky.social
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Bianca Introini @bianca-introini.bsky.social · 27/01/2025
I am very happy to share our latest work on the detailed cryo-EM structure of the NDH-PSI supercomplex of spinach. Thanks to Werner Kühlbrandt, Alex Hahn and @mpibp.bsky.social ! 🍃❄️🔬 You can find the paper in open access in Nature Structural and Molecular Biology: www.nature.com/articles/s41...
nature.com
Cryo-EM structure of the NDH–PSI–LHCI supercomplex from Spinacia oleracea - Nature Structural & Molecular Biology
Here, the authors report the structure of the nicotinamide adenine dinucleotide phosphate dehydrogenase–photosystem I–light-harvesting complex I supercomplex, providing insights into subunit interacti...
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