iiinova — where your digital self keeps evolving

Beth Psaila @bethpsaila.bsky.social · 09/09/2025

‼️See below terrific opportunity for a postdoc post with a leading group in Oxford, super exciting science! 🔥🔥👇

Beth Psaila @bethpsaila.bsky.social · 15/08/2025

Thanks Charley!! Take care though, platelet and meg biology is a fascinating world and once you start thinking about them it’s hard to stop…don’t get too distracted from those T cells!

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Beth Psaila @bethpsaila.bsky.social · 15/08/2025

we couldn't have done it without you Ben and Jeanne!

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Beth Psaila @bethpsaila.bsky.social · 15/08/2025

Thrilled that our paper is in print @science.org!! *Platelets sequester cell free DNA, including free fetal and tumour-derived DNA* Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight

science.org

By sucking up DNA, clot-producing platelets could help diagnose cancer

The cells could be a new source of tumor DNA for liquid biopsies

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Beth Psaila @bethpsaila.bsky.social · 02/07/2025

MPN community (patients/families) - do join us with MPN voice tomorrow if you are interested to hear updates on all the exciting data presented at the recent European Haematology Congress @mpnvoice.bsky.social @mpnrf.bsky.social www.mpnvoice.org.uk/news/mpn-voi...

mpnvoice.org.uk

MPN Voice ‘virtual’ forum – Post EHA 2025 updates Thu 3 July 2025

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Beth Psaila @bethpsaila.bsky.social · 15/06/2025

Exciting times for mutCALR MPNs - lovely data from the ET cohort presented in late breaking abstract at @EHA_Hematology. Rapid platelet control after just 2 doses with 89% of patients benefitting from a molecular response with INCA033989. @mpnvoice.bsky.social @mpnrf.bsky.social @mpnhv.bsky.social

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Beth Psaila @bethpsaila.bsky.social · 29/04/2025

Exciting job opportunities here for *TWO* computational researchers to contribute to a new collaborative effort between the @imm.ox.ac.uk and @ludwigcancer.bsky.social focussing on progression to high risk blood cancers and secondary leukaemia. Come join our brilliant team!

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Beth Psaila @bethpsaila.bsky.social · 28/03/2025

Lovely sunset family picnic serenaded by the geese at the Costa Del Port Meadow. #beautifuloxford

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Beth Psaila @bethpsaila.bsky.social · 27/03/2025

Go to www.jobs.ox.ac.uk and search for Vacancy ID 178728 for the Data Coordinator) closing date 11th April) and/or 178808 for the RA posts (closing date 16th April). We look forward to hearing from you !

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Beth Psaila @bethpsaila.bsky.social · 27/03/2025

We are recruiting!! Ads now live for a Data Coordinator and 2 Research Assistants/biobankers to join a new @ludwigcancer.bsky.social - @imm.ox.ac.uk joint initiative to prevent progression from early- to advanced blood cancer. Joint posts with Adam Mead+others in Oxford Ludwig. Links below

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Reposted by Beth Psaila

Roychoudhuri Lab @roychoudhurilab.bsky.social · 05/03/2025

Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U

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Reposted by Beth Psaila

MRC Weatherall Institute of Molecular Medicine @imm.ox.ac.uk · 24/02/2025

Rare Disease Day is coming up this Friday (28th Feb) 🧪 We spoke with Sarah Gooding, a clinician scientist in @rosschapmanlab.bsky.social's group at the MRC WIMM researching multiple myeloma - a currently incurable type of bone marrow cancer that desperately requires friendlier therapies.

youtu.be

Rare Disease Day 2025: Multiple Myeloma

YouTube video by MRC Weatherall Institute of Molecular Medicine

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Beth Psaila @bethpsaila.bsky.social · 19/02/2025

Congrats Rebekka - look forward to reading this!!

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Beth Psaila @bethpsaila.bsky.social · 18/02/2025

Check out @imm.ox.ac.uk latest video on innovation - we are fortunate to work in such a dynamic environment, bridging biological discovery and clinical translation @ox.ac.uk @cancerresearchuk.org

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Beth Psaila @bethpsaila.bsky.social · 18/02/2025

Check out @abattacks.bsky.social’s new and improved bone marrow organoid model - preprint below. More cell types (lymphoid progenitors and osteo- lineage), myeloma modelling and a cool method to improve scalability!

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Beth Psaila @bethpsaila.bsky.social · 29/01/2025

Super proud of brilliant NIH-OxCAM PhD student ZoeWong for winning the Doug Higgs Best Abstract award at Oxford Centre for Haematology Day @ox.ac.uk @ouhospitals.bsky.social @imm.ox.ac.uk, for her collab project with @alexrampotas.bsky.social. They are racking up prizes betw them…paper coming!

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Beth Psaila @bethpsaila.bsky.social · 23/01/2025

Great paper from @immunothrombosis.bsky.social group - platelets alter their functional properties with time since thrombogenesis. Important implications for transfusion storage time!

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Beth Psaila @bethpsaila.bsky.social · 23/12/2024

Join Us for the MPN Voice Virtual Forum! 🗓 Date: Monday, 6 January 2025 🕒 Time: 4:30 PM – 6:00 PM (GMT)📍 Location: Online (Zoom). Registration is now open! Focusing on the latest updates from the American Society of Hematology (ASH). linktr.ee/Mpnvoice

linktr.ee

MPN Community: Resources, Support & Donation Options | Linktree

MPN Voice empowers patients with MPNs. Find support groups, resources, and ways to donate to the cause.

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Beth Psaila @bethpsaila.bsky.social · 14/12/2024

So proud of DrLaurenMurphy passing PhD @imm.ox.ac.uk with flying colours.Grateful that she was brave enough to join as 2nd lab recruit 6yrs ago, and determined enough to make a huge success of a high-risk-high-reward PhD inspired by a @cancerresearchuk.org sandpit!Thanks examiners ProfsCurry&Gibbins

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Reposted by Beth Psaila

Linde Miles @lindemileslab.bsky.social · 11/12/2024

Make sure to get your talk submissions in! Can't wait for this conference and the all-star speakers/science!!

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Beth Psaila @bethpsaila.bsky.social · 08/12/2024

Terrific talk from the brilliant @antoniorromera.bsky.social this morning on how cells tolerate whole genome duplication and implications for cancer evolution. Check it out on the virtual platform if you missed it!

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Beth Psaila @bethpsaila.bsky.social · 08/12/2024

Very well deserved @alexrampotas.bsky.social ! We are thrilled to work with you and the CAR-T team

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Reposted by Beth Psaila

Alex Rampotas @alexrampotas.bsky.social · 08/12/2024

Very pleased to present the results of a UK wide collaborative study on real world efficacy and safety of Momelotininb - >60% anaemia responses at 6 months -G1-2 peripheral neuropathy (15%) -unexpected thrombocytosis (?hepcidin dysregulation due to AVCR1 inhibition) #ASH24 @bethpsaila.bsky.social

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Beth Psaila @bethpsaila.bsky.social · 07/12/2024

Sunrise and moonset beyond the Coronado Bridge on a beautiful run around San Diego bay this morning

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Beth Psaila @bethpsaila.bsky.social · 06/12/2024

It’s a long old way from @imm.ox.ac.uk Oxford to #ASH24 San Diego - but grateful for the stunning views flying over Greenland and Utah…and arrived to sunset over SD bay

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Beth Psaila @bethpsaila.bsky.social · 05/12/2024

All packed and ready for #ASH24 @ash-hematology.bsky.social! Just trying to decide which essential item to leave behind to get my suitcase to close

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Beth Psaila @bethpsaila.bsky.social · 29/11/2024

and also not to be missed - Ros Cooper and Dan Royston's oral abstract 'mapping the human bone marrow in MPNs using Spatial Transcriptomics'

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Beth Psaila @bethpsaila.bsky.social · 29/11/2024

Finally - thanks to a collaborative effort from the NCRI MPN subgroup across the UK - we are super excited to share a poster presenting 'real-world' efficacy and safety data of momelotinib for patients with myelofibrosis and anaemia

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Beth Psaila @bethpsaila.bsky.social · 29/11/2024

(3) Camelia Benlabiod presents her work from her PhD with Caroline Marty & Isabelle Plo @ Gustave Roussy on dissecting the cell-of-origin of mutCALR driven MPNs, and how del52 and ins5 elicit different signalling responses

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Beth Psaila @bethpsaila.bsky.social · 29/11/2024

(2) @alexrampotas.bsky.social from Pule/Roddie Labs @uclofficial.bsky.social presenting joint work (co-led by Zoe Wong from my group)-1st-in-class CAR-T against mutCALR MPNs & evaluation in the relevant human tissue environment using @abattacks.bsky.social bone marrow organoids model

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Beth Psaila @bethpsaila.bsky.social · 29/11/2024

Do swing by to hear: (1) @antoniorromera.bsky.social present his fascinating work on how megakaryocytes tolerate whole genome duplication, implications for genome integrity & cancer evolution

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Beth Psaila @bethpsaila.bsky.social · 29/11/2024

Excited for #ASH24 & thrilled that *3* brilliant folks from the team have oral presentations, travel awards and 2/3 nominated for **best of ASH**!! @imm.ox.ac.uk @ox.ac.uk @cancerresearchuk.org @ludwigcancer.bsky.social

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