Reposted by Antonio Rodriguez RomeraCharlotte Brierley @ckbrierley.bsky.social · 10/06/2025🚨🚨Paper out! 🚨🚨 Delighted to share our work, now published in @natgenet.nature.com 🧬! shorturl.at/94s5S We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n Illustration: Hratch Arbach 🧵👇 184
Reposted by Antonio Rodriguez RomeraCamelia Benlabiod @cameliabenlabiod.bsky.social · 10/12/2024As we’re coming towards the end of #ASH2024 I’d like to express my gratitude for the great science, company and feedback! @antoniorromera.bsky.social @alexrampotas.bsky.social @bethpsaila.bsky.social 1102
Reposted by Antonio Rodriguez RomeraBeth Psaila @bethpsaila.bsky.social · 08/12/2024Terrific talk from the brilliant @antoniorromera.bsky.social this morning on how cells tolerate whole genome duplication and implications for cancer evolution. Check it out on the virtual platform if you missed it! 1101
Reposted by Antonio Rodriguez RomeraBeth Psaila @bethpsaila.bsky.social · 29/11/2024and also not to be missed - Ros Cooper and Dan Royston's oral abstract 'mapping the human bone marrow in MPNs using Spatial Transcriptomics' 053
Reposted by Antonio Rodriguez RomeraBeth Psaila @bethpsaila.bsky.social · 29/11/2024Finally - thanks to a collaborative effort from the NCRI MPN subgroup across the UK - we are super excited to share a poster presenting 'real-world' efficacy and safety data of momelotinib for patients with myelofibrosis and anaemia 153
Reposted by Antonio Rodriguez RomeraBeth Psaila @bethpsaila.bsky.social · 29/11/2024(3) Camelia Benlabiod presents her work from her PhD with Caroline Marty & Isabelle Plo @ Gustave Roussy on dissecting the cell-of-origin of mutCALR driven MPNs, and how del52 and ins5 elicit different signalling responses 253
Reposted by Antonio Rodriguez RomeraBeth Psaila @bethpsaila.bsky.social · 29/11/2024(2) @alexrampotas.bsky.social from Pule/Roddie Labs @uclofficial.bsky.social presenting joint work (co-led by Zoe Wong from my group)-1st-in-class CAR-T against mutCALR MPNs & evaluation in the relevant human tissue environment using @abattacks.bsky.social bone marrow organoids model 173
Reposted by Antonio Rodriguez RomeraBeth Psaila @bethpsaila.bsky.social · 29/11/2024Do swing by to hear: (1) @antoniorromera.bsky.social present his fascinating work on how megakaryocytes tolerate whole genome duplication, implications for genome integrity & cancer evolution 153
Reposted by Antonio Rodriguez RomeraPride in STEM @prideinstem.bsky.social · 18/11/2024November 18 is the International Day of LGBQTIA+ People in STEM! Today more than ever we want to stress the importance of communities, building connections, and raising each other up. Let's keep leaving our mark for the betterment of us all! 🏳️⚧️🏳️🌈 #QueerinSTEM prideinstem.org/lgbtstemday/ 8867369