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Bahareh Ajami Lab

@baharehajami.bsky.social
230 followers 147 following 28 posts

Immunologist by heart,#microglia, Immigrant, mom, Triple Negative breast cancer survivor “hopefully”, Opinions mine. #AD, #ALS, #PD

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Bahareh Ajami Lab @baharehajami.bsky.social · 07/07/2026
Excited to share that our work is featured on the cover of the July issue of @natneuro.nature.com
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Bahareh Ajami Lab @baharehajami.bsky.social · 18/05/2026
Excited to share our paper published today in @NatureNeuro: www.nature.com/articles/s41... Using spatial proteomics, we identified a previously undescribed plaque-associated microglial population that emerged only when morphology and spatial context were integrated with protein expression #Microglia
nature.com
Spatial proteomic analysis in human Alzheimer’s disease brains enables identification of microenvironment-dependent microglial cell states - Nature Neuroscience
Myeloid cells show marked heterogeneity in Alzheimer’s disease. This study introduces CODEX-CNS, a single-cell spatial proteomics pipeline, and identifies a human microglial subpopulation enriched in ...
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Bahareh Ajami Lab @baharehajami.bsky.social · 15/04/2026
#Hiring Staff Scientist: Seeking expertise in: Microglial biology, ALS (required), Neuroimmunology / single-cell / spatial approaches. iPSCs, CRISPER. Thrilled to share our lab has been awarded its first NIH R01 #NOA! Project: α5 integrin mechanisms in #ALS pathology.
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saligramalab.bsky.social @saligramalab.bsky.social · 29/01/2026
#NOA is in #today from #NIH. We are very much looking for #postdocs with expertise in #TCR #molecular #biology and #protein #engineering #autoimmunity
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Joe Sabatino @jsabatino37.bsky.social · 27/08/2025
Modeling of T cell-mediated autoimmune pituitary disease using human induced pluripotent stem cell-originated organoid www.nature.com/articles/s41...
nature.com
Modeling of T cell-mediated autoimmune pituitary disease using human induced pluripotent stem cell-originated organoid - Nature Communications
Cytotoxic T lymphocytes (CTL) have been implicated in anti-PIT-1 hypophysitis, an autoimmune disease, but direct evidence is lacking. Here the authors use induced pluripotent stem cells to generate pi...
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Bahareh Ajami Lab @baharehajami.bsky.social · 13/07/2025
Thanks #ALSNorthwest for featuring #Ajamilab and our work in ALS: alsnorthwest.org/research-app...
alsnorthwest.org
Research Appeal 2025 | ALS Northwest
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Waggoner Lab @labwaggoner.bsky.social · 13/06/2025
Review @eurjimmunol.bsky.social Meningeal Immunity: Anatomy, Function, and Neonatal Unique Features onlinelibrary.wiley.com/doi/10.1002/...
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SFU Faculty of Science @sfuscience.bsky.social · 02/06/2025
Simon Fraser University invites applications from world-renowned researchers for the Canada Excellence Research Chairs (CERC) 2026 competition, offering up to $8M over eight years to support innovative and impactful research. Learn more and apply by June 30: www.sfu.ca/vpacademic/a...
sfu.ca
Canada Excellence Research Chairs (CERC) 2026 Competition
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David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 15/05/2025
Inspired by Vietnam-era activism, Stand Up For Science is hosting a series of teach-ins around the USA this summer, focusing on the importance of science and science funding. I’m doing one May 30th in Silver Spring. Many of you should consider doing one too, and I’m happy to help you plan it 🦑🧪🌎
Flier for the talk
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Beth Stevens @bethstevenslab.bsky.social · 10/05/2025
Let’s get the word out about the importance of federal funding of curiosity -driven science We all have similar stories to share
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Johnson Lab - University of Iowa @campylobacterlab.bsky.social · 09/05/2025
Hey y'all! My department is conducting a search for an assistant or associate professor in bacteriology. It's pretty broadly defined. If you know anyone who's looking for a great department that does awesome science - please send them our way! You can DM me with any questions you have 😀
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Shannon Macauley @macauleylab.bsky.social · 09/05/2025
This is unbelievable! All funding announcements for F30, F31, F32 awards expired May 8, 2025. No more Fs.
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Bahareh Ajami Lab @baharehajami.bsky.social · 11/04/2025
Had a truly fantastic time @MDAnderson as the inaugural speaker for the #CancerNeuroscience Seminar Series! Grateful to the amazing faculty, trainees, and staff for such a warm and inspiring visit. Thanks to all who attended! 🧠🧬 #Neuroimmunology #Neurodegeneration #Neuroscience
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Bahareh Ajami Lab @baharehajami.bsky.social · 08/03/2025
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Brittany Barker @brittanysbarker.bsky.social · 28/02/2025
Only 1 week until the Stand Up For Science rally at the OR capitol! We'll be hearing from Rep. Andrea Salinas and at least 4 renowned scientists. Rally with me to defend science from censorship and cuts! Let's make this big! #sciencenotsilence #standupforscience2025 @standupforscience.bsky.social
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Bella Rauch @rauchlab.bsky.social · 21/02/2025
Join me in standing up for science on March 7. in Salem, Oregon! Tell your friends and bring them too!! This is a nation wide event, with every state having at least one gathering. We need to show up strong!!! standupforscience2025.org
A flyer for the “stand up for science” event March 7, 2025, at the Oregon capitol (Salem)
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Chrystal Starbird @drstarbird.bsky.social · 10/02/2025
If only that breast cancer commercial ended with a notice about all the research funding cuts the current administration is pushing through and how it has immediate negative impacts on breast cancer research and screening.
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Jeremy Berg @jeremymberg.bsky.social · 09/02/2025
F99/R00 AND K99/R00 DIVERSITY AWARD APPLICANTS If you have applied for a F99/R00 or K99/R00 Diversity award and the study section for review is not listed on your eRA Commons page, please reach out to me. DM me, email berg.grants.2029@gmail.com, Signal jeremymberg.78 THANK YOU
media.tenor.com
a picture of a cartoon character with the words call me on it
ALT: a picture of a cartoon character with the words call me on it
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Bahareh Ajami Lab @baharehajami.bsky.social · 29/01/2025
Neuropathy pain has been the most debilitating side effect of chemotherapy for me with no treatment. This reports summarize it very well!
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Bahareh Ajami Lab @baharehajami.bsky.social · 02/01/2025
Ok this is cool!
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Bahareh Ajami Lab @baharehajami.bsky.social · 31/12/2024
Very interesting! Love to see biotech’s big breakthrough at the end of each year!
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Paul Frankland @franklandlab.bsky.social · 17/12/2024
Scientist position at The Hospital for Sick Children in Toronto. We are looking for neuroscientists with interests in the molecular and cellular bases of cognition. The position is open-rank, and the successful candidate will also be appointed at U Toronto. Deadline is Feb 15th. Come join us!
career.sickkids.ca
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Graeme Cumming @gscumming.bsky.social · 17/12/2024
We are hiring two postdocs. The first position is co-funded with The Australian Institute of Marine Sciences and will involve research on #marine connectivity with a stellar team, based in Perth. This is a 3-year full-time research position. More at external.jobs.uwa.edu.au/en/job/51901...
external.jobs.uwa.edu.au
Prospective staff : Jobs at UWA : IN DEVELOPMENT
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asamelson @asamelson.bsky.social · 25/11/2024
Come join my lab!! Starting in 2025 at UCLA!
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Valerie Tornini @valetornini.bsky.social · 09/12/2024
We are openly recruiting at all levels at the Tornini Lab at the University of California, Los Angeles (UCLA)! Please share with your networks. For more information, please check the info below, visit www.torninilab.org, or email me directly at vtornini at ucla dot edu. Thank you in advance!
Open recruitment for the Tornini Lab
Department of Integrative Biology and Physiology & Institute for Society and Genetics
Hispanic Serving Institution Infrastructure Initiative
University of California, Los Angeles (UCLA)
www.torninilab.org
We are a new developmental, cell, and molecular biology lab interested in understanding the
genetics of vertebrate neurodevelopment.
We use genome engineering, single-cell technologies, behavioral analyses, pharmacological
profiling, confocal imaging, genomics, and computational biology using the vertebrate
zebrafish (Danio rerio) system and other models (like sea lamprey) for evolutionary studies.
Our work is driven by curiosity, independence and teamwork, fun, a sense of urgency, and a
desire to understand how networks of genes regulate brain and organismal development. This
work can help us better understand basic mechanisms of what happens in human
developmental disorders or diseases and can inform novel therapeutic strategies.
We are recruiting across all levels.
Our lab works in multiple complementary areas (please see below).
We’re looking to match motivated people with what motivates them in a supportive and
engaging environment.
We are recruiting staff research scientists (1-2 years after undergrad+), graduate students (open
rotation positions), postdocs, and other positions as relevant.
While multiple of our projects are already funded, we strongly support candidates to identify
and apply for your own fellowships/grants with the full mentorship and resources of the lab.
Like our research? Think you might be a good fit?
Consider joining us!
For more information, please visit our website, the next page, or contact Val at: vtornini at ucla
dot edu
UCLA is an equal opportunity employer. Novel micropeptides in vertebrate neurodevelopment
 Using zebrafish models, we
ask: what are these proteins; what are their functions in neurodevelopment; what are other
“ignored” or “dark proteome” genes we are missing; and what can they reveal about human
neurodevelopmental disorders or diseases?
Chromatin regulators in vertebrate development and behavior
A growing group of evolutionarily conserved chromatin regulators have been identified as
genes linked with neurodevelopmental disorders, such as autism. In many cases, patients may
struggle with co-occurring conditions that impact daily life in childhood and adulthood,
including seizures, sleeplessness or sleep disruptions, and autoimmune disruptions. How do
these genes work to establish and maintain neural cell types during development, and in turn
shape circuits during early critical periods, including interactions with the environment, to
establish organismal physiological processes? 

Non-neuronal regulation during development and aging
Non-neuronal cell types, including oligodendrocytes and microglia, have emerged as key
players in shaping neurodevelopment and into adulthood. How are the cellular, molecular, and
physiological dynamics of these cell types in developing and aging brains affected in mutant
genetic models linked to neurodevelopmental disorders? Can we target these cells to
modulate neural dysregulation and resulting behaviors in these mutant models?

Evolution of vertebrate brain cell states
We seek to understand the principles of how novel genes co-evolve with the emergence of
neural cell types found only in vertebrates.
We use cross-species genomics and functional approaches with the jawless vertebrate model,
sea lamprey, to elucidate the roles of vertebrate-specific genes on the gene regulatory
networks.
Bioethics, neuroethics, and genetics
We seek to integrate evidence-based methods throughout our projects to investigate and address bioethical considerations in this research domain.
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Bahareh Ajami Lab @baharehajami.bsky.social · 10/12/2024
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Eric Topol @erictopol.bsky.social · 08/12/2024
Guardians of the Brain. A brief review of 6 recent, important reports that help us understand the brain-immune system axis erictopol.substack.com/p/guardians-... in the new Ground Truths, open-access (free) relevance: #LongCovid, brain tumors, multiple sclerosis, ME/CFS, autoimmunity
The brain's immune protection from its borders, including the bone marrow of the skull and 3 meninges layers
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Bahareh Ajami Lab @baharehajami.bsky.social · 08/12/2024
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