Sign in

Katie Chapple

@katiechapple.bsky.social
101 followers 226 following 3 posts

#neuroimmunologist researching glial-axonal interaction in the context of #multiplesclerosis -- PostDoc in Julia Edgars lab at University of Glasgow She/Her🏳️‍🌈🏳️‍⚧️Views=mine axo-glialgroup.co.uk

PostsRepliesMedia
Reposted by Katie Chapple
Vanja Tepavcevic @tepavcevicvanja.bsky.social · 04/08/2026
The final version of our article is available at www.nature.com/articles/s41...
nature.com
Monocarboxylate transporter 2 regulates maintenance of myelin and axonal integrity by oligodendrocytes - Nature Communications
Metabolic determinants of white matter integrity remain elusive. Here, the authors show downregulation of MCT2 in oligodendrocytes in progressive MS, and then demonstrate its role in myelin maintenanc...
054
Katie Chapple @katiechapple.bsky.social · 31/07/2026
📢 Thrilled to share our new paper @juliae.bsky.social! We show that myelin does more than insulate axons: it contains an activity-responsive transport system, TRAM, that moves organelles and helps maintain axonal health 🧠🔬 👏 Huge thanks to all our collaborators. 🔗 www.nature.com/articles/s41...
nature.com
An activity-modulated transport route across myelin (TRAM) for motor-driven organelle transfer in oligodendrocytes - Nature Neuroscience
Axons require intracellular transport of cargoes between the soma and the terminus. The authors show a related logistical challenge exists at smaller scale with respect to the interaction of process-b...
1136
Reposted by Katie Chapple
Multiple Sclerosis @multiplesclerosis.bsky.social · 24/06/2026
What connects autoimmune conditions? Four things we learnt from BBC’s Woman’s Hour www.mssociety.org.uk/research/lat...
mssociety.org.uk
What connects autoimmune conditions? Four things we learnt from BBC’s Woman’s Hour
We’re partners in Connect Immune Research – a project trying to link the science of autoimmune conditions. Last week, BBC Radio 4’s Woman’s Hour programme spoke about it in a special episode on women’...
022
Reposted by Katie Chapple
Michael D Kornberg @mdkornberg.bsky.social · 19/06/2026
www.nature.com/articles/s41...
nature.com
Monocarboxylate transporter 2 regulates maintenance of myelin and axonal integrity by oligodendrocytes - Nature Communications
Metabolic determinants of white matter integrity remain elusive. Here, the authors show downregulation of MCT2 in oligodendrocytes in progressive MS, and then demonstrate its role in myelin maintenanc...
033
Katie Chapple @katiechapple.bsky.social · 25/02/2025
Officially launched (a few weeks ago)! It has been an exciting time working on this novel T cell therapy project for the past year with the aim to address a significant unmet need in solid cancer treatments #tcelltherapy #cancerresearch swarmoncology.bio/swarm-oncolo...
swarmoncology.bio
Swarm Oncology announces Martin Olin as Chief Executive Officer - Swarm Oncology
Swarm Oncology Unveils Highly Differentiated, Personalised T Cell Therapy Platform to Significantly Improve Treatment Outcome for Cancer Patients and Appoints Martin Olin as Chief Executive Officer
010
Reposted by Katie Chapple
Gill Wilson @gillwilson00.bsky.social · 27/11/2024
Our new preprint is here! We show eosinophils are retained in the bone marrow by everyone’s (our😊) favourite atypical #chemokine receptor ACKR2. #Eosinophil education of #monocytes promotes differentiation to #macrophages and bacterial elimination during E.coli #infection. Please read and share.
biorxiv.org
Eosinophils promote monocyte to macrophage differentiation and anti-bacterial immunity
Chemokine receptors control cell migration within the body. Here we reveal a novel interaction between eosinophils and monocytes in the bone marrow, indirectly controlled by the atypical chemokine rec...
1358