Specific goals and estimation targets for randomized clinical trials have still not been well defined for general outcome variables. Proponents of causal inference calculus have claimed to define goal...

Este livro responde a diversas questões relacionadas à análise estatística de dados, revisitando os principais conceitos e sugerindo métodos computacionais para os mais diversos delineamentos de estud...

Failure is part and parcel of research, but discussing it sometimes seems to be taboo in science. It doesn’t need to be.

Our methodology provides a practical framework for examining required sample sizes when developing or updating prediction models with continuous outcomes, focusing on achieving precise and equitable p...

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The mistaken belief that statistical methods can tell you what to believe drove the science replication crisis.

Coarsened exact matching (CEM) is often promoted as a superior alternative to propensity score matching (PSM) for addressing imbalance, model dependence, bias, and efficiency. However, this recommend...

Applied Psychophysiology and Biofeedback - The postural biofeedback technique has been of potential interest to postural rehabilitation, as it promotes conscious postural control and reduces sway,...

The current status of applied clinical prediction modeling is poor. Many models are developed with suboptimal methods and are not evaluated, and hence have little impact on clinical care. We review 12...

Results with confidence intervals (CIs) crossing the null should not be interpreted as indicating no effect. We assessed how often clinicians make this error and explored predictors of correct interpr...

We have studied 21 435 unique randomized controlled trials (RCTs) from the Cochrane Database of Systematic Reviews (CDSR). Of these trials, 7224 (34%) have a continuous (numerical) outcome and 14 211...