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Triad sou.

@triadsou.bsky.social
180 followers 338 following 484 posts

Biostatistician, Bioinformatician. My interests: Biostatistics, Bioinformatics, Survival Analysis, Meta-analysis, Diagnostic Statistics, and Causal Inference. linktr.ee/tridasou

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Triad sou. @triadsou.bsky.social · 11/09/2026
No cure for cure models: killed by competing risks. Hein Putter, Per Kragh Andersen. Lifetime Data Analysis. link.springer.com/article/10.1...
link.springer.com
No cure for cure models: killed by competing risks - Lifetime Data Analysis
Cure models have become increasingly popular over the last couple of decades. An appealing element of cure models is the idea that part of the population is immune to the event of interest. We argue t...
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Triad sou. @triadsou.bsky.social · 10/09/2026
A Unified Framework for Rerandomization using Quadratic Forms. Kyle Schindl, Zach Branson. Journal of the American Statistical Association. www.tandfonline.com/doi/full/10....
tandfonline.com
A Unified Framework for Rerandomization using Quadratic Forms
When designing a randomized experiment, one way to ensure treatment and control groups exhibit similar covariate distributions is to randomize treatment until some prespecified level of covariate b...
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Triad sou. @triadsou.bsky.social · 10/09/2026
Statistics for Climate Science: Differentiation and Integration. Bo Li, Trevor Harris. Annual Review of Statistics and Its Application. doi.org/10.1146/annu...
doi.org
Statistics for Climate Science: Differentiation and Integration
Climate science increasingly relies on statistical tools to evaluate and synthesize diverse datasets, including observations, reanalyses, paleoclimate proxies, and model simulations. Climate data diff...
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Triad sou. @triadsou.bsky.social · 10/09/2026
Book Review: Behaviour Analysis with Machine Learning Using R. Enrique Garcia Ceja. Chapman & Hall. 2022, 434 Pages. doi.org/10.1093/jrss...
doi.org
Behaviour Analysis with Machine Learning Using R
Machine-learning texts are often organized around individual algorithms. This book instead presents machine-learning methods through the applied task of in
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Triad sou. @triadsou.bsky.social · 10/09/2026
Bias correction for Chatterjee’s graph-based correlation coefficient. Mona Azadkia, Leihao Chen, Fang Han. Biometrika. doi.org/10.1093/biom...
doi.org
Bias correction for Chatterjee’s graph-based correlation coefficient
Summary. Azadkia & Chatterjee (2021) recently introduced a simple nearest-neighbour graph-based correlation coefficient that consistently detects both
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Triad sou. @triadsou.bsky.social · 03/09/2026
Bayesian Models in Health Technology Assessment. Gianluca Baio. Chapman & Hall 2026, 384 Pages. www.routledge.com/Bayesian-Mod...
routledge.com
Bayesian Models in Health Technology Assessment
Bayesian models in Health Technology Assessment aims at presenting a thorough and yet accessible description of the philosophy underlying the Bayesian approach to statistical inference, as specificall...
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Triad sou. @triadsou.bsky.social · 03/09/2026
How to be SMART in oncology: A practical framework to assess the contribution of phase using sequential multiple adaptive randomized treatment designs. Kristine R. Broglio, Elizabeth F. Krakow, Erica E. M. Moodie. Clinical Trials. journals.sagepub.com/doi/abs/10.1...
journals.sagepub.com
How to be SMART in oncology: A practical framework to assess the contribution of phase using sequential multiple adaptive randomized treatment designs - Kristine R. Broglio, Elizabeth F. Krakow, Erica...
Background: Sequential multiple adaptive randomized treatment designs can generate registrational-quality evidence for the contribution of phase in perioperativ...
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Triad sou. @triadsou.bsky.social · 01/09/2026
Finite-Sample Adjustments in Estimating Equations for Correlated Overdispersed Count Outcomes With Application to Cluster Randomized Trials. Ying Zhang, John S. Preisser. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Finite‐Sample Adjustments in Estimating Equations for Correlated Overdispersed Count Outcomes With Application to Cluster Randomized Trials
Generalized estimating equations (GEE) produce population-averaged estimates of treatment effects in marginal mean models for correlated count outcomes, when intra-cluster correlations are considered...
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Triad sou. @triadsou.bsky.social · 26/08/2026
Bayesian Machine Learning for Estimating Optimal Dynamic Treatment Regimes With Ordinal Outcomes. Xinru Wang, Tanujit Chakraborty, Bibhas Chakraborty. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Bayesian Machine Learning for Estimating Optimal Dynamic Treatment Regimes With Ordinal Outcomes
Dynamic treatment regimes (DTRs) are sequences of decision rules designed to tailor treatments based on patients' treatment history and evolving disease status. Ordinal outcomes frequently serve as p....
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Triad sou. @triadsou.bsky.social · 25/08/2026
Sparse maximum likelihood estimation of regression models. Min Tsao. Canadian Journal of Statistics. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Sparse maximum likelihood estimation of regression models
For regression model selection and estimation, we study a small set of candidate models of maximum likelihood from which all information criteria such as the Akaike information criterion (AIC) and th...
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Triad sou. @triadsou.bsky.social · 20/08/2026
Blinded sample size recalculation in randomized controlled trials with analysis of covariance. Takumi Kanata, Yasuhiro Hagiwara, Koji Oba. Biometrics. doi.org/10.1093/biom...
doi.org
Blinded sample size recalculation in randomized controlled trials with analysis of covariance
Abstract. In randomized controlled trials, covariate adjustment can improve statistical power and reduce the required sample size compared with unadjusted
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Triad sou. @triadsou.bsky.social · 19/08/2026
Random-effects meta-analysis via generalized linear mixed models: A Bartlett-corrected approach for few studies. Keisuke Hanada, Tomoyuki Sugimoto. Biometrics. doi.org/10.1093/biom...
doi.org
Validate User
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Triad sou. @triadsou.bsky.social · 19/08/2026
Bayesian semiparametric modeling of biomarker variability in joint models. Sida Chen, Jessica K Barrett, Marco Palma, Jianxin Pan, Brian D M Tom. Biometrics. doi.org/10.1093/biom...
doi.org
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Triad sou. @triadsou.bsky.social · 19/08/2026
Comparing performance of three propensity score weighting methods for continuous exposures in nutritional epidemiology. Yuriko Muramatsu, Tosiya Sato, Hirohito Sone, Shiro Tanaka. BMC Medical Research Methodology. doi.org/10.1186/s128...
doi.org
Client Challenge
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Triad sou. @triadsou.bsky.social · 16/08/2026
Optimal Dynamic Treatment Regimes for High-Dimensional Accelerated Failure Time Model. Shijie Zhao, Wei Zhao. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Optimal Dynamic Treatment Regimes for High‐Dimensional Accelerated Failure Time Model
The increasing prevalence of high-dimensional covariates presents a significant challenge to precision medicine. To overcome this, we propose a novel multi-stage optimal dynamic treatment regime meth...
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Triad sou. @triadsou.bsky.social · 16/08/2026
Statistical Methods in Generative Artificial Intelligence. Edgar Dobriban. Annual Review of Statistics and Its Application. doi.org/10.1146/annu...
doi.org
Statistical Methods in Generative Artificial Intelligence
Generative artificial intelligence (AI) is emerging as an important technology, promising to be transformative in many areas. At the same time, generative AI techniques are based on sampling from prob...
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Triad sou. @triadsou.bsky.social · 14/08/2026
Methods of Selective Inference for Linear Mixed Models: A Review and Empirical Comparison. Matteo D'Alessandro, Magne Thoresen. International Statistical Review. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Methods of Selective Inference for Linear Mixed Models: A Review and Empirical Comparison
Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant...
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Triad sou. @triadsou.bsky.social · 14/08/2026
Bounds for the regression parameters in dependently censored survival models. Ilias Willems, Jad Beyhum, Ingrid Van Keilegom. Journal of the Royal Statistical Society Series B: Statistical Methodology. doi.org/10.1093/jrss...
doi.org
Bounds for the regression parameters in dependently censored survival models
Abstract. We propose a semiparametric model to study the effect of covariates on the distribution of a censored event time while making minimal assumptions
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Triad sou. @triadsou.bsky.social · 13/08/2026
Recent criteria and simple rules agreed often on required sample size for developed clinical prediction models. Ewout Steyerberg, Toby Hackmann, Ben van Calster, Maarten van Smeden, Laure Wynants. Journal of Clinical Epidemiology. www.sciencedirect.com/science/arti...
sciencedirect.com
Recent criteria and simple rules agreed often on required sample size for developed clinical prediction models
Adequate sample size is essential to the development of new prediction models with binary outcomes. We aim to relate recent approaches to traditional …
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Triad sou. @triadsou.bsky.social · 10/08/2026
What is estimated in cluster randomized crossover trials with informative sizes? A survey of estimands and common estimators. Kenneth M Lee, Andrew B Forbes, Jessica Kasza, Andrew Copas, Brennan C Kahan, Paul J Young, Michael O Harhay, Fan Li. SMMR. journals.sagepub.com/doi/full/10....
journals.sagepub.com
What is estimated in cluster randomized crossover trials with informative sizes? A survey of estimands and common estimators - Kenneth M Lee, Andrew B Forbes, Jessica Kasza, Andrew Copas, Brennan C Ka...
The cluster randomized crossover (CRXO) trial, among other multi-period cluster randomized trial designs, can target average treatment effect (ATE) estimands th...
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Triad sou. @triadsou.bsky.social · 07/08/2026
Fixed or Random Effects: Analysis of Clustered Data. Kevin He, Xiangeng Fang, Yubo Shao, Nicholas Hartman, John D. Kalbfleisch. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Fixed or Random Effects: Analysis of Clustered Data
In analyzing clustered data, random effects (RE) and fixed effects (FE) models are two primary approaches. The RE model assumes that the cluster-specific effects are random and uncorrelated with indi...
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Triad sou. @triadsou.bsky.social · 23/07/2026
Book Review: Foundations of Bayesian Statistics for Data Scientists: With R and Python. Alan Agresti, Maria Kateri, Ranjini Grove, Antonietta Mira. Chapman & Hall/CRC, 2026, 452 pages. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
<citation type='book' id='insr70060-cit-0002'><bookTitle>Foundations of Bayesian Statistics for Data Scientists: With R and Python</bookTitle> <author><givenNames>Alan</givenNames> <familyName>Agresti...
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Triad sou. @triadsou.bsky.social · 21/07/2026
One-at-a-time knockoffs. Charlie K Guan, Zhimei Ren, Daniel W Apley. Biometrics. doi.org/10.1093/biom...
doi.org
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Triad sou. @triadsou.bsky.social · 09/07/2026
Risk of bias assessment for Mendelian randomisation studies: a guide. Tabinda Jabeen, Adrienne O’Neil, Deborah N. Ashtree, Robyn E. Wootton, Luisa Zuccolo. European Journal of Epidemiology. link.springer.com/article/10.1...
link.springer.com
Risk of bias assessment for Mendelian randomisation studies: a guide - European Journal of Epidemiology
European Journal of Epidemiology -
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Triad sou. @triadsou.bsky.social · 07/07/2026
A Modified Random Survival Forest for Improving Prediction Accuracy in Case-Cohort and Generalized Case-Cohort Studies. Haolin Li, Haibo Zhou, David Couper, Jianwen Cai. Scandinavian Journal of Statistics. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
A Modified Random Survival Forest for Improving Prediction Accuracy in Case‐Cohort and Generalized Case‐Cohort Studies
Case-cohort and generalized case-cohort study designs offer cost-effective alternatives to full cohort studies for analyzing associations between risk factors and survival outcomes. However, existing...
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Triad sou. @triadsou.bsky.social · 07/07/2026
Asymptotic results for penalized quasi-likelihood estimation in generalized linear mixed models. Xu Ning, Francis K.C. Hui and A.H. Welsh. Statistica Sinica. www3.stat.sinica.edu.tw/statistica/J...
www3.stat.sinica.edu.tw
Xu Ning, Francis K.C. Hui and A.H. Welsh (2026). ASYMPTOTIC RESULTS FOR PENALIZED QUASI-LIKELIHOOD ESTIMATION IN GENERALIZED LINEAR MIXED MODELS. Vol 36 No. 3, 1257-1278. DOI:10.5705/ss.202023.0343.
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Triad sou. @triadsou.bsky.social · 07/07/2026
Bayesian statistics by arithmetic operations of conjugate distributions. Hang Qian. Statistica Sinica. www3.stat.sinica.edu.tw/statistica/J...
www3.stat.sinica.edu.tw
Hang Qian (2026). BAYESIAN STATISTICS BY ARITHMETIC OPERATIONS OF CONJUGATE DISTRIBUTIONS. Vol 36 No. 3, 1175-1192. DOI:10.5705/ss.202024.0052.
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Triad sou. @triadsou.bsky.social · 07/07/2026
Regression by composition. Daniel M Farewell, Rhian M Daniel, Mats J Stensrud, Anders Huitfeldt. Journal of the Royal Statistical Society Series B: Statistical Methodology. doi.org/10.1093/jrss...
doi.org
Regression by composition
We describe a modular regression framework in which covariate-dependent transformations are composed together and act on probability distributions. This fr
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Triad sou. @triadsou.bsky.social · 07/07/2026
Variable selection for clinical prediction models in low-dimensional data - a simulation study comparing traditional regression and machine learning methods. Johannes A. Vey, Georg Heinze, Meinhard Kieser. BMC Medical Research Methodology. link.springer.com/article/10.1...
link.springer.com
Variable selection for clinical prediction models in low-dimensional data - a simulation study comparing traditional regression and machine learning methods - BMC Medical Research Methodology
Purpose A wide range of methods exist for developing a clinical prediction model (CPM) and for performing variable selection. Our purpose was to develop a fair simulation study design and to investiga...
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Triad sou. @triadsou.bsky.social · 02/07/2026
Semiparametric fiducial inference for Cox models. Yifan Cui, Jan Hannig, Paul Edlefsen. Journal of the Royal Statistical Society Series B: Statistical Methodology. doi.org/10.1093/jrss...
doi.org
Semiparametric fiducial inference for Cox models
Abstract. R.A. Fisher introduced the fiducial distribution as a potential replacement for the Bayesian posterior distribution in the 1930s. During the past
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Triad sou. @triadsou.bsky.social · 02/07/2026
Recursive learning without collapse: a weighting-based stabilization framework. Hengzhi He, Shirong Xu, Guang Cheng. Journal of the Royal Statistical Society Series B: Statistical Methodology. doi.org/10.1093/jrss...
doi.org
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Triad sou. @triadsou.bsky.social · 02/07/2026
Covariate Adjustment for Wilcoxon Two Sample Statistic and Test. Zhilan Lou, Jun Shao, Ting Ye, Tuo Wang, Yanyao Yi, Yu Du. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Covariate Adjustment for Wilcoxon Two Sample Statistic and Test
We apply covariate adjustment to the Wilcoxon two sample statistic and Wilcoxon–Mann–Whitney test in comparing two treatments. The covariate adjustment through calibration not only improves efficienc....
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Triad sou. @triadsou.bsky.social · 30/06/2026
Extracting Interpretable Models from Tree Ensembles: Computational and Statistical Perspectives. Brian Liu, Rahul Mazumder, Peter Radchenko. Journal of the American Statistical Association. www.tandfonline.com/doi/full/10....
tandfonline.com
Extracting Interpretable Models from Tree Ensembles: Computational and Statistical Perspectives
Tree ensembles are nonparametric methods widely recognized for their accuracy and ability to capture complex interactions. While these models excel at prediction, they are difficult to interpret an...
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Triad sou. @triadsou.bsky.social · 26/06/2026
Rejoinder to Commentaries on “A Perspective on the Appropriate Implementation of ICH E9(R1) Addendum Strategies for Handling Intercurrent Events”. Thomas R. Fleming, et al. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Rejoinder to Commentaries on “A Perspective on the Appropriate Implementation of ICH E9(R1) Addendum Strategies for Handling Intercurrent Events”
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Triad sou. @triadsou.bsky.social · 24/06/2026
Reinterpreting I2 Thresholds: Toward Context-Specific Heterogeneity Assessment in Evidence Synthesis. Arturo J. Martí-Carvajal, David L. Streiner. Cochrane Evidence Synthesis and Methods. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Reinterpreting I2 Thresholds: Toward Context‐Specific Heterogeneity Assessment in Evidence Synthesis
Background The Cochrane Handbook's I2 categorization system (0%–25% “low”, 25%–75% “moderate”, ≥ 50% “high” heterogeneity) defines the standard approach to interpreting heterogeneity in meta-analysi...
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Triad sou. @triadsou.bsky.social · 24/06/2026
Leveraging external controls in clinical trials: estimands, estimation, assumptions. Bo Liu, Fan Li, Rury R. Holman, Laine E. Thomas. Journal of Biopharmaceutical Statistics. www.tandfonline.com/doi/full/10....
tandfonline.com
Leveraging external controls in clinical trials: estimands, estimation, assumptions
It is increasingly common to augment randomized controlled trial with external controls from observational data, to evaluate the treatment effect of an intervention. Traditional approaches to treat...
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Triad sou. @triadsou.bsky.social · 23/06/2026
Book Review: Fundamentals of Robust Machine Learning: Handling Outliers and Anomalies in Data Science. Resve Saleh, Sohaib Majzoub, A.K. Md. Ehsanes Saleh, John Wiley & Sons, 2025, xiv + 416 pages. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Fundamentals of Robust Machine Learning: Handling Outliers and Anomalies in Data Science, Resve Saleh, Sohaib Majzoub, A.K. Md. Ehsanes Saleh, John Wiley & Sons, 2025, xiv + 416 pages, £103.95, hardcover. ISBN: 978‐1‐394‐29437‐4
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Triad sou. @triadsou.bsky.social · 23/06/2026
Comparison of flexible parametric modeling and nonparametric methods to estimate restricted mean survival time: A simulation study. Ryusei Kimura, Shogo Nomura, Takahiro Hasegawa, Kohei Uemura. Journal of Biopharmaceutical Statistics. www.tandfonline.com/doi/full/10....
tandfonline.com
Comparison of flexible parametric modeling and nonparametric methods to estimate restricted mean survival time: A simulation study
In randomized controlled trials with survival time as the primary endpoint, it can be difficult to evaluate treatment effects using hazard ratios, particularly when the proportional hazards (PH) as...
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Triad sou. @triadsou.bsky.social · 22/06/2026
Simulated treatment comparisons with jackknife pseudo values for estimating population-adjusted marginal treatment effects. Sean Yiu, Kirsty Rhodes. Journal of Biopharmaceutical Statistics. www.tandfonline.com/doi/full/10....
tandfonline.com
Simulated treatment comparisons with jackknife pseudo values for estimating population-adjusted marginal treatment effects
Matching-adjusted indirect comparisons (MAIC) and simulated treatment comparisons (STC) are commonly used for indirect treatment comparisons when patient-level data are available for some treatment...
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Triad sou. @triadsou.bsky.social · 18/06/2026
INTACT: a method for integration of longitudinal physical activity data from multiple sources. Jingru Zhang, Erjia Cui, Hongzhe Li, Haochang Shou. Biometrics. doi.org/10.1093/biom...
doi.org
INTACT: a method for integration of longitudinal physical activity data from multiple sources
ABSTRACT. Wearable devices and digital phenotyping are increasingly used in observational and interventional studies to measure real-time biosignals such a
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Triad sou. @triadsou.bsky.social · 18/06/2026
Practical considerations when using the covariate-adjusted log-rank test for the analysis of time-to-event endpoints in oncology trials. Daniel Backenroth, Sanne Roels, Shiva Dibaj, Ting Ye, Fredrik Öhrn, Kelly Van Lancker. Biometrics. doi.org/10.1093/biom...
doi.org
Practical considerations when using the covariate-adjusted log-rank test for the analysis of time-to-event endpoints in oncology trials
ABSTRACT. Adjusting for prognostic baseline covariates in the design and analysis of randomized controlled trials can increase statistical power and improv
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Triad sou. @triadsou.bsky.social · 18/06/2026
Integration of aggregate data in causally interpretable meta-analysis by inverse weighting. Tat-Thang Vo, Tran Trong Khoi Le, Sivem Afach, Stijn Vansteelandt. Biometrics. doi.org/10.1093/biom...
doi.org
Integration of aggregate data in causally interpretable meta-analysis by inverse weighting
ABSTRACT. Obtaining causally interpretable meta-analysis results is challenging when there are differences in the distribution of effect modifiers between
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Triad sou. @triadsou.bsky.social · 17/06/2026
A generalized difference-in-differences estimator for stepped-wedge cluster-randomized trials. Lee Kennedy-Shaffer. Biometrics. doi.org/10.1093/biom...
doi.org
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Triad sou. @triadsou.bsky.social · 15/06/2026
cv: An R Package for Cross-Validating Regression Models. John Fox, Georges Monette. Journal of Statistical Software. www.jstatsoft.org/article/view...
jstatsoft.org
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Triad sou. @triadsou.bsky.social · 14/06/2026
How should covariates be handled in randomized trials? Empirical evidence from 50 trials and recommendations for practice. Yulin Shao, Liangbo Lyu, Menggang Yu, Bingkai Wang. Journal of Clinical Epidemiology. www.sciencedirect.com/science/arti...
sciencedirect.com
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Triad sou. @triadsou.bsky.social · 14/06/2026
AIC for many-regressor heteroskedastic regressions. Stanislav Anatolyev. Journal of Econometrics. www.sciencedirect.com/science/arti...
sciencedirect.com
AIC for many-regressor heteroskedastic regressions
The original and corrected Akaike information criteria (AIC) have been routinely used for model selection for ages. The penalty terms in these criteri…
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Triad sou. @triadsou.bsky.social · 10/06/2026
Selective randomization inference for adaptive experiments. Tobias Freidling, Qingyuan Zhao, Zijun Gao. Journal of the Royal Statistical Society Series B: Statistical Methodology. doi.org/10.1093/jrss...
doi.org
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Triad sou. @triadsou.bsky.social · 08/06/2026
bayesNMF: Fast Bayesian Poisson NMF with Automatically Learned Rank Applied to Mutational Signatures. Jenna M. Landy, Nishanth Basava & Giovanni Parmigiani. Journal of Computational and Graphical Statistics. www.tandfonline.com/doi/full/10....
tandfonline.com
bayesNMF: Fast Bayesian Poisson NMF with Automatically Learned Rank Applied to Mutational Signatures
Bayesian Poisson Non-Negative Matrix Factorization (NMF) is widely used to model count data, including in cancer mutational signature analysis. However, standard Gibbs samplers rely on computationa...
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Triad sou. @triadsou.bsky.social · 08/06/2026
Causal Inference: A Tale of Three Frameworks. Linbo Wang, Thomas S. Richardson, James M. Robins. Journal of Data Science. jds-online.org/journal/JDS/...
jds-online.org
Causal Inference: A Tale of Three Frameworks | Journal of Data Science | School of Statistics, Renmin University of China
Causal inference is a central goal across many scientific disciplines. Over the past several decades, three major frameworks have emerged to formalize causal questions and guide their analysis: the po...
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Triad sou. @triadsou.bsky.social · 08/06/2026
Automatic debiased machine learning for covariate shifts. V Chernozhukov, M Newey, W K Newey, R Singh, V Syrgkanis. Biometrika. doi.org/10.1093/biom...
doi.org
Automatic debiased machine learning for covariate shifts
SUMMARY. We present machine learning estimators for causal and predictive parameters under covariate shift, where covariate distributions differ between tr
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