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Juan (胡安)

@angiopteris.bsky.social
81 followers 96 following 11 posts

Juan Carlos Lopez-Agudelo PhD student at Academia Sinica, Taiwan Agrobacteria | Plant-pathogen interactions | Bacterial evolution Never stop exploring 🌱

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Reposted by Juan (胡安)
Joe Hanly @hanliconius.bsky.social · 22/09/2026
I hate to do this with real data, but this is a persistent data vis issue in chromosome synteny riparian plots that we Need to get better at. Left, a synteny plot published today. Right, a rearranged version with exactly the same gross arrangement but with reordered chromosomes:
chromosome synteny riparian plot in which every chromosome has crossing lineschromosome synteny plot in which no chromosomes have crossing lines. The underlying structure is identical.
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Reposted by Juan (胡安)
Thorsten Langner @thorstenlangner.bsky.social · 01/07/2026
‼️Job altert🚨📢 please spread the word: We're looking for a postdoctoral researcher to join our new department "Phytopathology and Plant Protection" at @unihalle.bsky.social. www.verwaltung.uni-halle.de/DEZERN3/AUSS...
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Reposted by Juan (胡安)
Bacteriophage Lab of Institut Pasteur @phagepasteur.bsky.social · 01/07/2026
We’re happy to introduce phageFACTor (Functional Annotation and Curation Tool) 👩‍💻Developed by Tanaïs Moreau, our most recent PhD candidate, and building on Phold, we were able to improve annotation of prophage genes by as much as 50% 🧬 You should check it out github.com/TMs-code/pha...
In this example, we're showing the improvement in the percentage of annotated genes from prophage "Maintenon" from Clostridium innocuum (doi: 10.1186/s40168-023-01541-x) using the phageFACTor pipeline
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Reposted by Juan (胡安)
Jiorgos Kourelis @jiorgoskourelis.bsky.social · 04/06/2026
📢 PDRA Position - Plant Immune Receptor Bioengineering at Imperial College London 🌱 Start: Aug 2026 (flexible) 🧪 Wet lab + bioinformatics 📅 Up to 3 years (ERC-funded) 📍 South Kensington, on site ℹ️ shorturl.at/VIITk 🔗 kourelislab.com #PlantImmunity #PlantPathology 🙏 Share with interested candidates!
shorturl.at
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Reposted by Juan (胡安)
Sofya Garushyants @garushyants.bsky.social · 12/06/2026
Our paper on the YprA family of helicases and their roles in bacterial defence is now out! We describe ARMADA, a defence system synergise with Druantia and show that both systems spread horizontally on a novel type of mobile genetic element that we call SPIDERs www.sciencedirect.com/science/arti...
sciencedirect.com
YprA-family helicases provide the missing link between diverse prokaryotic immune systems
Bacteria and archaea possess an enormous variety of antiviral immune systems that often share homologous proteins and domains. YprA-family helicases a…
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Reposted by Juan (胡安)
Diana Gómez De La Cruz @dianagdlc.bsky.social · 05/06/2026
So proud to see this story finally out!🎉 We added new data since our previous preprint—transgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short 🧵 and link to the original preprint thread on X👇 www.science.org/doi/10.1126/...
science.org
Molecular mimicry of a pathogen virulence target by a plant immune receptor
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
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Juan (胡安) @angiopteris.bsky.social · 04/06/2026
Very exciting news, congratulations! :)
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Plant Science Spotlight @plant-sci.bsky.social · 30/05/2026
🌿🧬Bryophytes have a larger gene family space than vascular plants. New super pangenome analysis of 123 genomes reveals new immune receptors & microbial genes acquired through horizontal transfer Small in size. Big in genetic toolkit #plantscience @natgenet.nature.com www.nature.com/articles/s41...
nature.com
Bryophytes hold a larger gene family space than vascular plants - Nature Genetics
A super-pangenome analysis incorporating 123 newly sequenced bryophyte genomes reveals that bryophytes exhibit a larger number of unique and lineage-specific gene families than vascular plants.
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Reposted by Juan (胡安)
Ye Jin (Jennie) Ahn @yejinjennieahn.bsky.social · 22/05/2026
A new preprint is OUT! 🚨 Thrilled to finally share our work on how decoy diversification underpins the regulation of an NLR-mediated autoimmunity. Check out the full story on @bioRxiv: www.biorxiv.org/content/10.6... (1/6)
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Adam Steinbrenner @adsteinbrenner.bsky.social · 13/05/2026
We are excited to release the BAT!🦇🚨 We've used this phylogenetic analysis pipeline in our lab for years, and grad Ben Sheppard now presents a Github release and preprint. I run BAT analyses almost daily. It makes exploring gene families routine, customizable, and fun🧵
pipeline logo
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Reposted by Juan (胡安)
Ákos T Kovács @evolvedbiofilm.bsky.social · 11/05/2026
See a brief review summarizing the use of synthetic microbial communities (SynComs) for revealing the ecology of specialized metabolites [my holiday break writing exercise] portlandpress.com/essaysbioche... #MicrobiomeEcology at Institute of Biology Leiden (IBL)
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Andrew Roger @andrewjroger.bsky.social · 06/05/2026
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models academic.oup.com/mbe/article/...
academic.oup.com
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models
Abstract. IQ-TREE (https://iqtree.github.io/) is a widely used open-source software tool for efficiently inferring phylogenetic trees under maximum likelih
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Reposted by Juan (胡安)
Jana Sperschneider @jsperschneider.bsky.social · 07/05/2026
📢 EffectorGeneP is finally here! Stop missing small, single-exon or orphan genes from your favourite pathogen genome. Current tools only annotate 15%-78% of effector genes, EffectorGeneP finds 95% - including the large AvrSr26 family in stem rust. #Bioinformatics 📖 www.biorxiv.org/content/10.6...
biorxiv.org
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Freddie King @freddie-king.bsky.social · 01/05/2026
Very excited to see our recent work on NRG1 organellar targeting now published! It has been a pleasure working with Tarhan on this, combining synthetic biology/genetics with some incredible microscopy 🤝 www.science.org/doi/10.1126/...
science.org
A helper NLR channels organellar calcium to trigger plant immunity
Upon activation, plant nucleotide-binding leucine-rich repeat (NLR) immune receptors are known to assemble into oligomeric resistosomes that insert into the plasma membrane, forming calcium (Ca2+)–per...
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European Commission @ec.europa.eu · 09/04/2026
Big opportunities for researchers 🌍 We are investing nearly €400 million to help researchers share their work and collaborate with the best scientific teams across the EU. The 2026 Marie Skłodowska-Curie Actions Postdoctoral Fellowships are now open. More: link.europa.eu/PNxpxw
Graphic announcing the MSCA Postdoctoral Fellowships 2026 call. It shows the opening date (9 April 2026), closing date (9 September 2026), and a budget of €399.05 million. The design features scientific visuals such as cells, a leaf, and lab elements on a dark background, with the European Commission logo at the bottom.
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Freddie King @freddie-king.bsky.social · 23/04/2026
Excited to share our preprint using Rhizobium rhizogenes AS109 for agroinfiltration, facilitating strong transient expression across non-model plants including sweet potato, mustard, Medicago and faba bean! doi.org/10.64898/202... 1/7
doi.org
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Juan (胡安) @angiopteris.bsky.social · 23/04/2026
Finally out! A follow-up to our Rhizobium rhizogenes story with @tolgaboz.bsky.social and Lida. We hope this work will make it easier to study many other plant species. www.biorxiv.org/content/10.6...
biorxiv.org
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Gitta Coaker @gittacoaker.bsky.social · 18/04/2026
We are hiring! We’re excited to recruit a postdoc to our lab at UC Davis to work on plant immune engineering and single-cell analyses of plant pathogen interactions. Apply by June 1. Please repost. www.coakerlab.org/postdoctoral...
Postdoctoral Scholar position in the Coaker group
University of California, Davis
We are seeking a Postdoctoral Scholar to join our research program focused on immune receptor engineering and spatial analyses of plant pathogens interactions using computational and imaging approaches. The position will involve integration of molecular, imaging, and computational approaches. Relevant publications from the laboratory include Nature Plants (2025, PMID: 40721669), Proceedings of the National Academy of Sciences (2024, PMID: 38814867), and Cell Reports (2023, PMID: 37342910). https://www.coakerlab.org/
Qualifications:
•	Ph.D. in plant biology, molecular biology, genetics, computational biology, or a related field
•	Strong background in genomics and/or computational biology 
•	First author publications in peer-reviewed journals
•	Ability to work both independently and collaboratively in a multidisciplinary environment
•	Experience in plant innate immunity is preferred

Application Instructions:
The position is initially available for two years, with the possibility of extension based on performance and funding. Salary is based on the University of California postdoctoral salary scale (https://www.ucop.edu/academic-personnel-programs/_files/2025-26/represented-oct-2025-scales/t23.pdf). The salary range for this position is $69,073-$82,836 US Dollars/year. 
Review of applications will begin June 1, 2026 and will continue until the position is filled.
Please submit a CV, a brief statement of research interests (~1 page), and contact information for three references to glcoaker@ucdavis.edu. The research statement should describe your previous work, how your expertise aligns with ongoing research in the lab, and potential future research directions.
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Juan (胡安) @angiopteris.bsky.social · 15/04/2026
Congratulations Mauricio! You and your work truly deserve it :)
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Biochemical Society @biochemsoc.bsky.social · 14/04/2026
As an emerging leader in plant innate immunity, we're thrilled to present Mauricio Contreras with a 2027 Early Career Research Award! Alongside advocating for Open Science and preprint review, Mauricio's "activation-and-release" and "NLR resurrection" models are already referenced worldwide.
Award announcement for Dr. Mauricio P. Contreras from University of Tübingen, Germany, receiving the Early Career Research Award at The Biochemical Society 2027 Awards.
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Cecile Lorrain @ccilelorrain.bsky.social · 15/04/2026
Thrilled to share our paper now out in Nature Plants 🎉 We developed a genome-host association (GHA) approach to study pathogen adaptation directly from field metadata by using the originating host cultivar as phenotype. www.nature.com/articles/s41...
nature.com
Genome–host association mapping reveals wheat pathogen genes involved in host specialization - Nature Plants
This study introduces genome–host association (GHA), leveraging natural epidemics to map the genetic landscape of host adaptation in the pathogen Zymoseptoria tritici. Applied to 832 wheat fungal stra...
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Khaled_Selim Lab @selimlab.bsky.social · 09/04/2026
"Research is often described as ‘basic’, but there is nothing basic about it. The links between discovery-based research and downstream applications aren’t always clear at the outset. Although a translational output may require years to achieve" www.nature.com/articles/s41...
nature.com
Advancing microbiology through foundational science - Nature Microbiology
Microorganisms have tremendous potential to impact humanity, but such revelations are only possible in the light of foundational, discovery-based microbiology research.
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 11/04/2026
Reconstructing plant beneficial bacterial consortia by integrating dilution-to-extinction microbiome perturbation with genome-resolved synthetic ecology www.biorxiv.org/content/10.64898/20…
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Caitlyn Cardetti, PhD @caitlyncardetti.bsky.social · 09/04/2026
Dear Conference Organizers, Please for the love of all things, provide an easily printable agenda. These weird web interfaces to build your own and apps are just not it. I'm sure you could find better ways to spend our conference fees. Maybe on more coffee? #AcademicSky
media.tenor.com
a furry animal with yellow eyes is laying on a rock
ALT: a furry animal with yellow eyes is laying on a rock
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Oleksandr Maistrenko @omaistrenko.bsky.social · 06/04/2026
There is a lot of undescribed prokaryotic diversity in existing whole-genome metagenomic data! www.nature.com/articles/s41...
nature.com
Unbinned contigs expand known diversity in the global microbiome - Nature Microbiology
Re-analysis of over 92,000 metagenomes reveals hundreds of thousands of previously undescribed Bacterial and Archaeal clades hidden in plain sight.
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Bruna de Sousa @desousabfs.bsky.social · 02/03/2026
Super happy to share our new review about how bacteria adapt to plant environment over the years. It was a collaborative effort between the network #redplantmicro of researchers interested in molecular biology and plant microbe interactions.
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Sophien Kamoun @kamounlab.bsky.social · 27/02/2026
Never outdated: 12 timeless tips for effective leadership. blog.venturemagazine.net/12-tips-for-...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 22/02/2026
Microbial Cohorts: Bringing Ecological Meaning to the Modularity Concept of Co-Occurrence Networks #ISMECommun by Felix Milke, @sarilog.bsky.social, Meinhard Simon, Armando Pacheco-Valenciana & Sinikka T Lennartz academic.oup.com/ismecommun/a...
academic.oup.com
Microbial Cohorts: Bringing Ecological Meaning to the Modularity Concept of Co-Occurrence Networks
Abstract. Microbial communities are structured through complex interactions that are difficult to observe directly. Co-occurrence networks offer a way to i
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Manuel Lera-Ramirez @manu-lera.bsky.social · 24/11/2025
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software ✅ Free 🔓 Open Source 🧬 More cloning methods than SnapGene 🤖 Can be automated with python 👨‍🔬 Built by a researcher — for researchers! 👉 Check it out at opencloning.org
A cloning strategy as depicted in the OpenCloning website
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Sophien Kamoun @kamounlab.bsky.social · 14/01/2026
Kamounia striata -- a 300 million year-old oomycete fossil! Thank you Christine Strullu-Derrien ☺️ doi.org/10.1016/j.is...
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Tiffany Lowe-Power stands with Minnesota @tlowepower.bsky.social · 29/12/2025
Interesting
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Craig MacLean @craigmaclean.bsky.social · 09/10/2025
This is first paper from a new line of research in my lab, with more to come soon. If interested in PDPs I highly recommend this @baym.lol paper www.nature.com/articles/s41... and this classic from Matti Jalasvuori royalsocietypublishing.org/doi/10.1098/...
nature.com
Diverse and abundant phages exploit conjugative plasmids - Nature Communications
Some phages use plasmid-encoded conjugation proteins as receptors to infect their bacterial hosts, making their host range dependent on horizontal transfer of the plasmid. Here, the authors present a method for identification of new plasmid-dependent phages, and find that they are common and abundant in wastewater and their genetic diversity is largely unexplored.
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PM Delaux @pierremarcdelaux.bsky.social · 09/10/2025
A first dive in fern x pathogen interaction! More to come! Congratulations @baptistebio.bsky.social @jacquet-chris.bsky.social et al.!
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JiangzhaoQian.bsky.social @jiangzhaoqian.bsky.social · 25/09/2025
Thrilled to share that our TEtrimmer paper has just been published in Nature Communications! A big thank you to all collaborators — the article is now online ;) www.nature.com/articles/s41...
nature.com
TEtrimmer: a tool to automate the manual curation of transposable elements - Nature Communications
Transposons are repetitive DNA sequences that are hard to identify and map accurately. TEtrimmer automates key manual steps, enabling faster and more reliable annotation of transposable elements in any genome.
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Facundo Romani @fromani.bsky.social · 22/09/2025
Very important paper and resource. Bryophyte genomes expanded by one order of magnitude. www.nature.com/articles/s41...
nature.com
Bryophytes hold a larger gene family space than vascular plants - Nature Genetics
A super-pangenome analysis incorporating 123 newly sequenced bryophyte genomes reveals that bryophytes exhibit a larger number of unique and lineage-specific gene families than vascular plants.
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Vaughn Cooper @vscooper.micropopbio.org · 13/08/2025
For those recalling the awesome session on ecology and evolution of zoonoses at GRC MPB 2023, or those who wish they were there, these authors and topic were on Rosie's and my wish list. Ancient pathogen genomes have much to say. www.cell.com/cell/fulltex...
cell.com
Bronze Age Yersinia pestis genome from sheep sheds light on hosts and evolution of a prehistoric plague lineage
A Yersinia pestis genome from a Bronze Age domesticated sheep provides insight into the host range, evolution, and possible transmission scenarios of an ancient lineage of the plague-causing bacteria,...
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Reposted by Juan (胡安)
Matthew Hahn @3rdreviewer.bsky.social · 06/08/2025
This looks like an amazing tool www.biorxiv.org/content/10.1...
biorxiv.org
Phyling: phylogenetic inference from annotated genomes
Phyling is a fast, scalable, and user-friendly tool supporting phylogenomic reconstruction of species phylogenies directly from protein-encoded genomic data. It identifies orthologous genes by searchi...
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Reposted by Juan (胡安)
The Plant Cell @theplantcell.bsky.social · 01/08/2025
A root-specific NLR network mediates immune signaling of resistance genes against plant parasitic nematodes (Daniel Lüdke , Toshiyuki Sakai , Jiorgos Kourelis , et al) doi.org/10.1093/plce... #PlantScience
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Phil Carella @philcarella.bsky.social · 23/07/2025
I’m very grateful and excited to start our ARIA-funded project on redesigning plant immunity!
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Gitta Coaker @gittacoaker.bsky.social · 23/07/2025
Conserved Phytophthora effector protease cleaves BAK1 to suppress defense. www.nature.com/articles/s41...
nature.com
A conserved Phytophthora apoplastic trypsin-like serine protease targets the receptor-like kinase BAK1 to dampen plant immunity - Nature Plants
Phytophthora secretes a conserved trypsin-like serine protease, PsTry1, that suppresses apoplastic immunity by cleaving the extracellular domain of the co-receptor BAK1, revealing a novel mechanism by...
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Juan (胡安) @angiopteris.bsky.social · 17/07/2025
It fills me with pride listening to Yi-Feng Chen talking about his research at #2025ISMPMI. I am happy to see the fruits of his effort. Congratulations!
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Tolga Bozkurt @tolgaboz.bsky.social · 07/07/2025
Plz RT. We are looking for a postdoc to join our collborative project on AI-guided bioengineering of plant immune receptors @tolgaboz.bsky.social and @jiorgoskourelis.bsky.social labs: www.jobs.ac.uk/job/DNV032/r...
jobs.ac.uk
Research Associate in Programmable Plant Immunity at Imperial College London
Apply for the Research Associate in Programmable Plant Immunity role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
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Juan (胡安) @angiopteris.bsky.social · 17/07/2025
Very happy to finally present my poster to a very interested audience! It’s always a pleasure to discuss about agro, commonly seen as a tool, but still a (cool) plant pathogen. Still at #2025ISMPMI, so if you are interested in my work, don’t be shy to say hi!
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Juan (胡安) @angiopteris.bsky.social · 14/07/2025
It was an amazing sciences day at #2025ISMPMI! Right after the “Population, biology, ecology and genomics” session, I had the opportunity to have lunch and discuss about this topic with the co-chair @honour.bsky.social
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Ming Tommy Tang @tommytang.bsky.social · 14/07/2025
String manipulation is a critical daily task for bioinformaticians. Here is a cheatsheet using stringr: rstudio.github.io/cheatsheets... I probably use stringr::str_replace() once every other day... to clean up metadata (of course!) #rstats
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Juan (胡安) @angiopteris.bsky.social · 13/07/2025
Just arrived to #2025ISMPMI! I am very excited to learn a lot about plant-pathogen interactions from all of you! If you want to learn more about A4 and our current progress, feel free to visit me at P-211 on Wednesday!
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Mauricio Contreras @mpcontreras.bsky.social · 09/07/2025
Thrilled to share our latest preprint! This work started during my PhD and was finished together with @jmadhuprakash.bsky.social. We found a Phytophthora infestans L-shaped effector that bridges a host TOL protein to activated NLRs to suppress immunity! www.biorxiv.org/content/10.1... 1/15
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Pingtao Ding (he/him) @dinglab.bsky.social · 01/07/2025
Cell-type-specific execution of effector-triggered immunity Our new preprint is online, 1 July⬇️ With @himanshuchhillar.bsky.social @leonardojo.bsky.social Amey Redkar @kaisakajala.bsky.social @jonathandgjones.bsky.social For early readers & community feedback🙏🏼 #openscience @erc.europa.eu
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Francois Keck @francoiskeck.bsky.social · 08/07/2025
So, has this reached us yet? Yes, it did. I did a quick #rstats analysis of the literature in ecology. 📊 🔗 See my new blog post: www.pieceofk.fr/the-rise-of-...
Barplot showing how the usage of different typographic character has changed in abstracts between 2021 and 2025 and showing that the use em dash indeed has doubled.
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Sophien Kamoun @kamounlab.bsky.social · 05/07/2025
This is textbook cell biology material by chin-hang Wu and colleagues . Check it out 👇 #plantsci #plantpath #immunology #NLRbiology www.biorxiv.org/content/10.1...
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