Reposted by Alyssa SlickoAlexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 6h#nobelprize #mednobel #modelorganism Time to update my slide 😀 1263
Reposted by Alyssa SlickoFlorent Waltz @florentwaltz.bsky.social · 6hHuge congratulations to all three Nobel Laureates, and especially Peter Hegemann! 👏 His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨ Proof that groundbreaking discoveries don't always come from animal models! 🔬 018368
Reposted by Alyssa SlickoJeremy Berg @jeremymberg.bsky.social · 29/09/2026Here is @jenna-m-norton.bsky.social explaining the issues and highlighting the letter. www.instagram.com/reel/Dd2xFUs... 3/3 063
Reposted by Alyssa SlickoJeremy Berg @jeremymberg.bsky.social · 29/09/2026Letter from the American Society of Clinical Investigation regarding recent projected changes in NIH K (career development) awards. beta.the-asci.org/news/advocac... 1/3beta.the-asci.orgOpen letter to the NIH regarding proposed changes to K awards - The American Society for Clinical InvestigationRead more about Open letter to the NIH regarding proposed changes to K awards at The American Society for Clinical Investigation 12315
Reposted by Alyssa SlickoMagnoliaBouton @magnoliabouton.bsky.social · 11/08/2026NIH plans to block international researchers on visas from accessing key funding avenue: the K99/R00. Devastating news for the international research training community, who strongly contribute to US biomedical research. All will feel this great loss! www.statnews.com/2026/08/07/n...statnews.comNIH plans to block international researchers on visas from accessing key funding avenueThe NIH plans to close the door on one of the few pathways available to international students on visas to forge a career in biomedical research in the U.S. 311486
Reposted by Alyssa SlickoGenetics Society of America @genetics-gsa.bsky.social · 24/09/2026Science needs your voice! A proposed Executive Order could give the White House a role in reviewing NIH research grants. It's essential that you contact your elected representatives and ask them to: 👉 Keep NIH grant decisions grounded in scientific merit and expert review 1/3🧵⬇️ 145
Reposted by Alyssa SlickoAmerican Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 22/09/2026NIH funding decisions should be made by scientific experts, not political appointees. Protecting rigorous peer review safeguards public trust, biomedical progress and U.S. scientific leadership. ➡️Learn more: www.asbmb.org/advocacy/pos... #ScienceServesUsAll #ASBMBAdvocates 01915
Reposted by Alyssa SlickoSheri @sagrill.bsky.social · 19/09/2026Incredibly excited to share my new preprint! 🪰🧬 Ever wondered how germ cells can specify their fate without having a dedicated transcriptional program? We found that germ cells keep the uncommitted chromatin state of the early embryo www.biorxiv.org/content/10.6...biorxiv.orgDecoupling Transcription from Cell Fate Preserves Germ Cell TotipotencyOnly germ cells can give rise to a totipotent embryo, yet a conserved transcriptional program for germ cell identity remains elusive. Profiling Drosophila primordial germ cells (PGCs) across embryogen... 24214
Reposted by Alyssa SlickoArjuna Rajakumar PhD @arjunarajakumar.bsky.social · 19/09/2026So proud of my lab mate @sagrill.bsky.social (whose on the job market 👀) for this magnum opus from @remlehmann.bsky.social lab @whiteheadinstitute.bsky.social ScRNA-seq of 🪰 germ cells reveals new biology, answers age old questions, and proposes new paradigms! 1/8 www.biorxiv.org/content/10.6... 35928
Reposted by Alyssa SlickobioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 18/09/2026Decoupling Transcription from Cell Fate Preserves Germ Cell Totipotency www.biorxiv.org/content/10.64898/20… 033
Reposted by Alyssa SlickoJason Rasgon @vectorgen.bsky.social · 17/09/2026Banger of a new RasgonLab study by Drs. Najmeh Nejat and Travis van Warmerdam on a new arthropod germline CRISPR delivery system. Knock-out AND knock-in by ORAL delivery! No more injections! Germline Engineering by Viral transduction (GEValT) 95927
Reposted by Alyssa SlickoMark Peifer (He, him) @peiferlabunc.bsky.social · 13/09/2026Hoping legal challenges at least delay this. It's sadly impressive that someone involved knows the things most likely to damage the US scientific enterprise 12713
Reposted by Alyssa SlickoGenetics Society of America @genetics-gsa.bsky.social · 01/09/2026🪰 A new study in #GENETICS demonstrates how the Stellate meiotic drive system in #Drosophila is active in contemporary populations, revealing its evolutionary significance. 🔗 buff.ly/UqEQJrQ 01410
Reposted by Alyssa SlickoJeremy Berg @jeremymberg.bsky.social · 01/09/2026For those in the mood for some seriously well-done gallows humor, I heartily recommend this... inpreparation.substack.com/p/nih-simpli...inpreparation.substack.comNIH Simplifies Grant Scoring To 👍 🤷♂️ 😂BETHESDA, MD—The National Institutes of Health announced Tuesday that it would replace its 50-year-old numerical scoring system with a streamlined three-emoji format, in which grant applications will ... 711440
Reposted by Alyssa SlickoBarbara Moran @moranwriter.bsky.social · 27/08/2026Yikes: “I cannot do my best work in America,” said Zamore. “I can’t recruit the best people to help me do that, and I can’t promise them an environment where they’ll be safe.” www.wbur.org/news/2026/08...wbur.orgWhy a UMass researcher is among the dozens leaving the U.S. for CanadaA renowned scientist at UMass Chan Medical School is moving his lab to Canada. The Canadian government named RNA researcher Phillip Zamore among the first recipients of awards that will total more tha... 22714
Reposted by Alyssa SlickoCarl Zimmer @carlzimmer.com · 26/08/2026Nature honors Dolly Parton's scientific legacy. www.nature.com/articles/d41...nature.comDolly Parton dies aged 80 – researchers celebrate her contributions to scienceThe country singer was an advocate for vaccines, public health, literacy and marginalized communities. 3736272
Reposted by Alyssa SlickoJeff Lewis @lewislab.bsky.social · 19/08/2026"I think we need to focus our critique on the question of who is doing the deciding and what is the basis for that decision." 032
Reposted by Alyssa SlickoJeff Lewis @lewislab.bsky.social · 19/08/2026"I encourage you to keep this in mind as you craft your response...My view is that outraged responses that imply or declare the misunderstanding that all NIH grant selection marches in lockstep with the peer review outcome, and/or should only follow the order of peer review, are a huge mistake." 145
Reposted by Alyssa SlickoElizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 14/08/2026The NIH just released a proposal that will apparently hide peer reviewers’ impact scores and percentiles from the research team, their institution, and NIH program officers. All the better to obscure how funding decisions will be made primarily via political review, I’m guessing.grants.nih.govNOT-OD-26-088: Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer ReviewNIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review NOT-OD-26-088. NIH 17394215
Reposted by Alyssa SlickoJournal of Cell Biology @jcb.org · 07/07/2026Meiotic CENP-C supports #centromere assembly and #kinetochore recruitment in #spermatogenesis. New study form Rachel S. Keegan, Dina Malkeyeva, Meg B. Weever, and Elaine M. Dunleavy @uniofgalway.bsky.social: rupress.org/jcb/article/... #CellCycle #CellDivision #Development #Meiosis #Drosophila 0158
Reposted by Alyssa SlickoJames Gagnon @james-gagnon.bsky.social · 04/08/2026In a new (ish) preprint, we used CRISPR barcodes to label germline stem cell clones in zebrafish, then tracked their contributions to sperm production for 2 years. Instead of staying stable, individual clones rose, fell, and disappeared over time. www.biorxiv.org/content/10.6...biorxiv.orgClonal dynamics deviate from neutral drift in zebrafish spermatogenesisSpermatogonial stem cells (SSCs) maintain male fertility, but how their clonal dynamics change with age remains poorly understood. Here, we use in vivo CRISPR barcoding in zebrafish to label SSCs and ... 25721
Reposted by Alyssa SlickoBarbara Mellone 🇺🇦 @centromellone.bsky.social · 24/07/2026Well, this explains A LOT www.biorxiv.org/content/10.6...biorxiv.orgTriplex DNA and inverted repeats cause long-read sequencing bias against simple satellite DNAWe recently showed that Oxford Nanopore Technologies (ONT) and Pacific Biosciences (PacBio) have very strong sequencing bias against simple satellites, probably caused by single-stranded DNA folding i... 1135
Reposted by Alyssa SlickoPeiwei Chen @peiwei-chen.bsky.social · 17/07/2026How do transposons jump when they’re released from host control? I babysat two chromosomes for 2 years, making sure they are ok without most piRNAs. Here’s what we found & excited to share my 1st postdoc paper: “piRNA loss unleashes episodic transposition bursts” www.biorxiv.org/content/10.6...biorxiv.orgpiRNA loss unleashes episodic transposition burstsIn Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon ex... 715369
Reposted by Alyssa SlickoNature Portfolio @natureportfolio.nature.com · 29/06/2026The world’s highest 10% of spenders are responsible for environmental damage estimated to be worth US $1.7–5.7 trillion (at 2017 values) each year, according to research in Communications Sustainability. go.nature.com/43KAHIz #econsky 🌎🧪 15431
Reposted by Alyssa SlickoNoam Ross @noamross.net · 23/06/2026Thousands of biomedical studies are stuck in limbo as NIH drags out renewals months after annual budgets expire. Since 2025, the rate of overdue renewals has TRIPLED. This leaves scientists unable to plan, keep staff employed, or maintain long-term research. grant-witness.us/posts/2026-0... #NIH 🧪grant-witness.usOverdue Grant Renewals at NIH and AHRQ – Grant WitnessThe government’s delays renewing in-progress research are leaving researchers in limbo. 4201138
Reposted by Alyssa SlickoMindy Weisberger @laminda.bsky.social · 24/06/2026Gutted for the staff affected by Scientific American's layoffs & for the uncertain future of a science magazine that fed curious minds & showed us what excellent science reporting looked like. I hate that the more we need good science writing (and writers), the fewer staff jobs there are to do it 113346
Reposted by Alyssa SlickoAsher HELLbein @asherelbein.bsky.social · 23/06/2026Employees at Scientific American were told today that the magazine has been sold to LabX Media Group, the outfit that runs Discover Magazine and IFLScience. And that means -- of course! -- editorial layoffs. The media mass extinction rolls ever onward. 101023397
Reposted by Alyssa Slickothe babahuck @tylerhuckabee.bsky.social · 13/06/2026eating in mexico as a european has gotta be like hearing music for the first time 418200863534
Reposted by Alyssa SlickoGenetics Society of America @genetics-gsa.bsky.social · 08/06/2026We urge GSA members and the genetics community to submit a public comment on the recently proposed OMB regulations—which pose drastic challenges to the scientific enterprise—by July 13, 2026! Submit your comments here: www.regulations.gov/document/OMB... 11816
Reposted by Alyssa SlickoNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 08/06/2026Comment here: www.regulations.gov/document/OMB...regulations.govRegulations.gov 074
Reposted by Alyssa SlickoStacey Ogden 🦔 @labogden.bsky.social · 03/06/2026Make some noise about this 🧪 www.npr.org/2026/06/03/n...npr.orgPresident Trump seeks control of science fundingThe White House Office of Management and Budget is moving to take more control of billions of dollars in federal grants. Critics say the proposed change would jeopardize the integrity of U.S. science. 8162103
Reposted by Alyssa SlickoMark Peifer (He, him) @peiferlabunc.bsky.social · 03/06/2026I have often been critical of the leadership @aaas.org but they just took action on the new OMB rules that will politicize science, speaking out and notifying members. I hope all take the time to follow their advice, contact Congress, and most important, post a comment www.aaas.org/news/aaas-st... 0228122
Reposted by Alyssa SlickoRangan Lab @ranganlab.bsky.social · 22/05/2026 @benforward3.bsky.social is running for State Rep in MA. Ben is a fellow scientist and fly biologist who has gone into public service, and I think supporting scientists running for office matters at every level. Support his campaign:https://secure.actblue.com/donate/ben-for-state-rep Please RT 044
Reposted by Alyssa SlickoScience Magazine @science.org · 23/05/2026Parents often fight about how to raise their children, but a mouse study suggests an even more basic form of parental conflict starts soon after conception when the chromosomes from each side come together. scim.ag/4um0LW3scim.agCan one parent silence the other’s genes? Natural ‘paramutations’ found in miceOdd phenomenon first seen in plants could explain puzzling disease inheritance patterns 0344
Reposted by Alyssa SlickoCarl T. Bergstrom @carlbergstrom.com · 22/05/2026“Units of the NIH are privately directing grantees to request permission in advance for any co-authorship with a scholar affiliated with a foreign institution, even if all the work was done in the United States.” Grantees also told to remove papers with foreign authors from progress reports.science.orgU.S. researchers face new restrictions on publishing with foreign collaboratorsNIH, NASA grantees are confused and concerned amid agencies’ piecemeal communication 31417259
Reposted by Alyssa SlickoMarvin Tanenbaum @marvintanenbaum.bsky.social · 13/05/2026For 40 years the 8-nt ‘Kozak Sequence’ was thought to mark sites of translation initiation. In a new study, we revise this model by identifying an ~80-nt sequence—the extended Translation Initiation Sequence (eTIS)— that guides ribosomes to correct start sites. 🧵 www.biorxiv.org/content/10.6...biorxiv.org 317878
Reposted by Alyssa SlickoMindy Weisberger @laminda.bsky.social · 11/05/2026All you have to do is spend literally 5 minutes on Bluesky to see how much scientists have to say about science, and how you could not get them to stop talking about science if you tried 320858
Reposted by Alyssa SlickoJeremy Berg @jeremymberg.bsky.social · 11/05/2026Open letter calling for the reinstatement of the National Science Board. This letter is from leaders of the National Academies Note: This does not refer to the leaders on paper such as presidents of the NAS, NAM, and NAE. www.standupforscience.net/nasem-letter... @standupforscience.netstandupforscience.netNASEM Open Letter to Congress demanding the restoration of the NSB — STAND UP FOR SCIENCESupport NASEM's open letter to Congress by signing your endorsement now! 8256118
Reposted by Alyssa SlickoThe New York Times @nytimes.com · 09/05/2026Bentonville, a town of 61,000 in northwest Arkansas, has become a national mecca for cycling and home to a world-class art museum. See how to spend your next visit at the charming, accessible destination in the Ozark Mountains. nyti.ms/4u3lAWj 21638
Reposted by Alyssa SlickoIsabel @isabelott.bsky.social · 07/05/2026These viruses have been known problems in Korea for so long that there’s literally a M*A*S*H episode about them. People work their whole careers on viruses most people have never heard of…so that you never have to hear about them. 201253370
Reposted by Alyssa SlickoHarmit Singh Malik @harmitmalik.bsky.social · 07/05/2026OMG! I can’t believe someone actually bought insurance for their car and house. This almost certainly means they planned to burn down their belongings! Not to mention life insurance for their spouse. How suspicious is that?! (Viral vaccines in the age of RFK Jr is probably the safest bet of all) 0452
Reposted by Alyssa SlickoSimon Hammann @simonhammann.bsky.social · 20/04/2026Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey. 191958537
Reposted by Alyssa SlickoDan Garisto @dangaristo.bsky.social · 25/04/2026Breaking: Trump has fired the membership of the National Science Board, which is oversees NSF. I have confirmed separately with multiple now-former members of NSB.democrats-science.house.govRanking Member Lofgren Reacts to Latest Trump Scheme to Undermine Science | House Committee on Science, Space and TechnologyThe House Committee on Science, Space and Technology 581055762
Reposted by Alyssa SlickoPeiwei Chen @peiwei-chen.bsky.social · 17/04/2026plz repost 🙏 we are looking for a technician to start this summer/fall for 1-2 years to work with me at Cornell in the labs of @cedricfeschotte.bsky.social and Andy Clark, in collaboration with @corriemoreau.bsky.social on flies & termites 🪰🐜🧬🔬 Ithaca is gorges! jobs.hr.cornell.edu/us/en/job/WD...jobs.hr.cornell.eduCALS- Technician I- Molecular Biology and Genetics in Ithaca, New York, United States of America | Research & Instructional Support at Cornell UniversityApply for CALS- Technician I- Molecular Biology and Genetics job with Cornell University in Ithaca, New York, United States of America. Research & Instructional Support at Cornell University 12841
Reposted by Alyssa SlickoJeffrey Ross-Ibarra @jrossibarra.bsky.social · 14/04/2026All these folks focusing on extending lifespans don't consider that we wouldn't need to extend lifespans if we didn't waste so much frickin' time doing captchas. 5435
Reposted by Alyssa SlickoProceedings of the National Academy of Sciences @pnas.org · 10/04/2026In a recent PNAS QnAs, Yukiko Yamashita explores how stem cells maintain the ability to both differentiate and revert, revealing new insights into cell identity and regeneration. Her work sheds light on mechanisms that could inform future disease research. Read more: ow.ly/zppo50YGHkU 011
Reposted by Alyssa SlickoWhitehead Institute @whiteheadinstitute.bsky.social · 13/04/2026Congratulations to Whitehead Institute trainees Elizabeth Black, Juntao Yu, and Tatsat Banerjee for being named as Damon Runyon Fellows — 3 of just 13 selected nationwide! Learn more about their efforts to advance cancer research: tinyurl.com/4dvhtzwr 061
Reposted by Alyssa SlickoWhitehead Institute @whiteheadinstitute.bsky.social · 07/04/2026This work, published in @pnas.org, also identifies the mechanisms that help determine whether a cell will self-renew, differentiate, or revert to a stem cell state. Yamashita shares more the findings in a conversation with @pnas.org: www.pnas.org/doi/10.1073/...pnas.orgQnAs with Yukiko Yamashita | PNASQnAs with Yukiko Yamashita 032
Reposted by Alyssa SlickoWhitehead Institute @whiteheadinstitute.bsky.social · 07/04/2026Stem cells can both renew themselves and give rise to cells that differentiate into specialized types like lung cells or blood cells. Now, a new study out of the Yamashita Lab uncovers how cells are able to preserve stem cell potential while adopting distinct identities. tinyurl.com/469utx4p 141
Reposted by Alyssa SlickoWhitehead Institute @whiteheadinstitute.bsky.social · 09/03/2026When closely related species mate, their offspring sometimes survive but can’t reproduce. New work from the Yamashita Lab shows that in hybrid male fruit flies, large Y-chromosome genes fail during RNA processing preventing sperm development: shorturl.at/MGyZe 041
