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Alyssa Pradhan

@alyssapradhan.bsky.social
2.5K followers 609 following 43 posts

Australian Infectious Diseases trainee | DPhil in Clinical Medicine @ndm.ox.ac.uk‬ Interested in equitable healthcare AI and tahini-based dips

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Reposted by Alyssa Pradhan
Bash the bug @bashthebug.net · 20/11/2025
Our team wore blue for World Antimicrobial Awareness Week 2025💙 Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance. #WAAW @oxfordbrc.bsky.social
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Reposted by Alyssa Pradhan
Scott McGrath @smcgrath.phd · 17/10/2025
An overemphasis on helpfulness makes LLMs vulnerable. Research shows models will comply with illogical medical requests, generating false information. This sycophantic tendency can be corrected with specific prompting and fine-tuning. #MedSky #MedAI #MLSky
nature.com
When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior - npj Digital Medicine
npj Digital Medicine - When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior
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Reposted by Alyssa Pradhan
JAMA @jama.com · 16/06/2025
Viewpoint: The sudden removal of all Advisory Committee on Immunization Practices (ACIP) members and changes to #COVID19 vaccine policy have critically weakened the US vaccine program. #MedSky ja.ma/43MpHvd
Advisory Committee on Immunization Practices at a Crossroads
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Reposted by Alyssa Pradhan
Karandeep(Singh) @kdpsingh.bsky.social · 16/11/2024
"All the data in the world will not make a difference, unless there are people ready to use it." — Atul Butte, MD, PHD, FACMI 2024 Morris F. Collen Award Winner
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Alyssa Pradhan @alyssapradhan.bsky.social · 28/05/2025
I like these papers where the risk from subtle patterns we pick up on clinically can be somewhat quantified: pubmed.ncbi.nlm.nih.gov/40345937/ #MedicalAI #MedSky #MLSky #DigitalHealth #AIinHealthcare
pubmed.ncbi.nlm.nih.gov
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Reposted by Alyssa Pradhan
Medical Attention Podcast @medicalattention.bsky.social · 10/05/2025
Can #LLMs introspect? Can they do maths? We're back (again) busting myths about #LLMs and #AIinmedicine! Listen now: podcasts.apple.com/au/podcast/m... #MedicalAI #MedSky #FOAMed #digitalhealth
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Reposted by Alyssa Pradhan
ProPublica @propublica.org · 20/02/2025
NEW: Pregnancy became far more dangerous in Texas after the state banned abortion, according to ProPublica’s first-of-its-kind analysis, which found the sepsis rate for women hospitalized as they miscarried in the 2nd trimester shot up by more than 50%. propub.li/43487Tj
propub.li
Texas Banned Abortion. Then Sepsis Rates Soared.
ProPublica’s first-of-its-kind analysis is the most detailed look yet into a rise in life-threatening complications for women experiencing pregnancy loss under Texas’ abortion ban.
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Alyssa Pradhan @alyssapradhan.bsky.social · 02/02/2025
#GPT-4 generated plain language notes improved comprehension of discharge notes, particularly in Black and Hispanic patients and those with decreased #healthliteracy. Very cool to see the practical effect of this work #MedicalAI #digitalhealth #MedSky #AI ai.nejm.org/doi/full/10....
ai.nejm.org
A Cross-Sectional Study of GPT-4–Based Plain Language Translation of Clinical Notes to Improve Patient Comprehension of Disease Course and Management
The 21st Century Cures Act provides patients with access to their clinical notes, but most patients, particularly those with limited health literacy, have difficulty understanding and utilizing the...
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Alyssa Pradhan @alyssapradhan.bsky.social · 29/01/2025
Interesting discussion with Hoffman, ft. some concerning sidestepping about regulation, conflating any guardrails with stifling innovation. Also interesting to see the anxiety around #DeepSeek immediately leading to justification / apology for tech billionaires.. #MLSky #digitalhealth #AI
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Alyssa Pradhan @alyssapradhan.bsky.social · 27/01/2025
I really like the detail in this paper! Exploring the bias in #LLM responses through counterfactuals, SHAP, embeddings (oh my) and looking at intersections of gender x ethnicity 😍 TLDR: #Algorithmicbias runs deep #MedSky #MLSky #digitalhealth #healthequity arxiv.org/abs/2410.16574
arxiv.org
How Can We Diagnose and Treat Bias in Large Language Models for Clinical Decision-Making?
Recent advancements in Large Language Models (LLMs) have positioned them as powerful tools for clinical decision-making, with rapidly expanding applications in healthcare. However, concerns about bias...
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Alyssa Pradhan @alyssapradhan.bsky.social · 20/01/2025
This is an interesting question but does the methodology address whether an LLM is "uncertain"? It would be interesting to see how the LLM reports of confidence in an answer correspond to probability of the token for that answer... #MLSky #medsky #healthcareAI www.nature.com/articles/s41...
nature.com
Large Language Models lack essential metacognition for reliable medical reasoning - Nature Communications
Large Language Models demonstrate expert-level accuracy in medical exams, supporting their potential inclusion in healthcare settings. Here, authors reveal that their metacognitive abilities are under...
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Alyssa Pradhan @alyssapradhan.bsky.social · 17/01/2025
Ever wondered what it’s like being stuck talking to me at a party? Look no further. #MedSky #MLSky #algorithmicbias #healthcareAI
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Alyssa Pradhan @alyssapradhan.bsky.social · 15/01/2025
"Replacement of just 0.001% of training tokens with medical misinformation results in harmful models more likely to propagate medical errors.... Corrupted models match the performance of their corruption-free counterparts on open-source benchmarks routinely used to evaluate medical LLMs."
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Reposted by Alyssa Pradhan
Dr. Annie Andrews @drannieandrews.com · 13/01/2025
If RFK Jr. is confirmed. @donttreadonkids.bsky.social
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Alyssa Pradhan @alyssapradhan.bsky.social · 09/01/2025
Interested to see what people's thoughts are regarding this #NEJMAI perspective 🧵 #MedSky #MLSky #algorithmicbias #healthcareAI #healthequity ai.nejm.org/doi/full/10....
ai.nejm.org
Ethical Use of Artificial Intelligence in Medical Diagnostics Demands a Focus on Accuracy, Not Fairness
Artificial intelligence (AI) promises to be a transformative technology for medicine and health care. As such, there is an increasing interest in ensuring its ethical use. In this perspective, we c...
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Reposted by Alyssa Pradhan
TRIPOD Statement @tripodstatement.bsky.social · 08/01/2025
Great to see "TRIPOD+AI and DECIDE-AI are the highest quality guidelines with respect to rigor of development and the involvement of the stakeholders" 😄 in academic.oup.com/jamiaopen/ar... Get TRIPOD+AI from www.bmj.com/content/385/... #MLSky #StatsSky #MedSky
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Stephen Pfohl @stephenpfohl.bsky.social · 18/12/2024
Check out our new paper "Tackling Algorithmic Bias and Promoting Transparency in Health Datasets: The STANDING Together Consensus Recommendations" jointly published in NEJM AI and The Lancet Digital Health, led by @jaldmn.bsky.social @xiaoliu.bsky.social
ai.nejm.org
Tackling Algorithmic Bias and Promoting Transparency in Health Datasets: The STANDING Together Consensus Recommendations
Without careful dissection of the ways in which biases can be encoded into artificial intelligence (AI) health technologies, there is a risk of perpetuating existing health inequalities at scale. O...
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Alyssa Pradhan @alyssapradhan.bsky.social · 03/01/2025
I agree with this Lancet Digital Health viewpoint that data harmonisation and funding for microbiology reference labs is a public health issue. Investment in the expertise to standardise and analyse this data in real time is also needed @thelancet.bsky.social www.thelancet.com/journals/lan...
thelancet.com
The importance of microbiology reference laboratories and adequate funding for infectious disease surveillance
Microbiology reference laboratories perform a crucial role within public health systems. This role was especially evident during the COVID-19 pandemic. In this Viewpoint, we emphasise the importance of microbiology reference laboratories and highlight the types of digital data and expertise they provide, which benefit national and international public health. We also highlight the value of surveillance initiatives among collaborative international partners, who work together to share, analyse, and interpret data, and then disseminate their findings in a timely manner.
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Alyssa Pradhan @alyssapradhan.bsky.social · 17/12/2024
Move over Spotify wrapped, it's time for 49 minutes of us chatting about the trends in #healthcareAI for 2024! #MLSky #MedSky #MedEd #Podcast
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Alyssa Pradhan @alyssapradhan.bsky.social · 15/12/2024
A cool illustration of the richness of routine laboratory data. In all the hype of #healthcareAI, this use to unveil patterns we can't perceive is particularly powerful. #MedSky #MLSky www.nature.com/articles/s41...
nature.com
Haematological setpoints are a stable and patient-specific deep phenotype - Nature
Complete blood count indices are tightly regulated around setpoints for decades in healthy adults, and represent a deep phenotype providing opportunities for investigating differential disease risks, ...
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Reposted by Alyssa Pradhan
Justin Beardsley @beardsley-j.bsky.social · 11/12/2024
Nice paper - tricky case. Patient w COVID-19 isolated for 7 months, impacting rehab. Rules and interpretation of tests were too rigid for lung Tx patient, long after IPC threat had passed. Authors @priyagargiddoc.bsky.social @alyssapradhan.bsky.social et al offer some solutions!
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Scott McGrath @smcgrath.phd · 06/12/2024
Tagging 🩺🖥️
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Reposted by Alyssa Pradhan
Eric Topol @erictopol.bsky.social · 05/12/2024
The opportunities, challenges and outlook for LLM-based agents in medicine and healthcare—our paper published today nature.com/articles/s42...
nature.com
LLM-based agentic systems in medicine and healthcare - Nature Machine Intelligence
Large language model-based agentic systems can process input information, plan and decide, recall and reflect, interact and collaborate, leverage various tools and act. This opens up a wealth of oppor...
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Alyssa Pradhan @alyssapradhan.bsky.social · 27/11/2024
Welcome to bsky @jenniferdmotter.bsky.social whose work on HIV+ to HIV+ transplant contributed to this policy change 😍👏🏽 www.hhs.gov/about/news/2... #IDSky #TxID #Medsky
hhs.gov
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Reposted by Alyssa Pradhan
Bennett Waxse @bwaxse.bsky.social · 20/11/2024
The ID march of shorter treatment is ok continues, this time for bacteremia (not including S. aureus). FYI, E. coli, Klebsiella, Enterococcus, and CoNS made up > 70% of organisms. By pathogen breakdown of risk difference emphasizes applicability of these results for GN bacteremia.
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Reposted by Alyssa Pradhan
Saira Butt, MD @sairabt.bsky.social · 19/11/2024
idsociety.quorum.us/campaign/811... #idsky #hivsky #idadvocacy #advocacy #idfellows #idfellowship Congress Is Making Funding Decisions Now: Urge Them to Protect ID/HIV Funding @idsainfo.bsky.social town hall
idsociety.quorum.us
Congress Is Making Funding Decisions Now: Urge Them to Protect ID/HIV Funding
Ask your members of Congress to support robust funding for vital ID/HIV programs.
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Alyssa Pradhan @alyssapradhan.bsky.social · 19/11/2024
Getting my predictions in early 😭 #IDSky
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Danielle Bitterman MD @daniellebitterman.bsky.social · 16/11/2024
🩺💡The Bitterman lab has spent much of the past year researching #LLMs for healthcare. This post summarizes our inroads into making LLMs safer and reliable for clinicians and patients: huggingface.co/blog/shanche.... We'll be at #EMNLP2024 - come chat if you have similar interests!
huggingface.co
What We Learned About LLM/VLMs in Healthcare AI Evaluation:
A Blog post by Shan Chen on Hugging Face
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Reposted by Alyssa Pradhan
BK. Titanji @boghuma.bsky.social · 14/11/2024
I lack the words to fully express how utterly devastating will be for public health and vaccines. The consequences will last for years and we may never fully recover. www.politico.com/news/2024/11...
politico.com
Trump to select Robert F. Kennedy Jr. to lead HHS
The choice will roil many public health experts after his years of touting debunked claims that vaccines cause autism.
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Alyssa Pradhan @alyssapradhan.bsky.social · 14/11/2024
One of the things I’ve really enjoyed about #AMIA2024 has been the thoughtful discussion about strategies to mitigate #algorithmicbias and promote #healthequity🧵
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Sébastien Poulin @sebpoule.bsky.social · 12/11/2024
Hey #IDsky #MedSky 👋 Do you know your Evans-based Medicine Rules ? You can now learn them with @skepticaliddoc.bsky.social on 🦋! Welcome 🤗
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Alyssa Pradhan @alyssapradhan.bsky.social · 12/11/2024
A great poster from both a content and user engagement perspective! #AMIA24 #indigenoushealth
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Ryan Radecki MD MS @www.evidencetriage.com · 12/11/2024
Examples of how, potentially, the routine maintenance of predictive models could allow bad actors to systematically insert trigger tokens to maliciously output an erroneous target state based on user inputs. #AMIA2024
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Alyssa Pradhan @alyssapradhan.bsky.social · 12/11/2024
Lots of discussion about #NLP for unstructured clinical notes over the past few days. Data from UTHealth in suicide risk detection demonstrates fine tuned #LLM > in context learning > BERT models with significant caveats of cost and training corpus size. #AMIA24 #MLSky #MedSky
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Alyssa Pradhan @alyssapradhan.bsky.social · 12/11/2024
Joining @smcgrath.phd on his quest to make #AMIA24 happen. Some sobering results on the very high hallucination rates of GPT-4 use for ED discharge summaries by UCSF.
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Irene Chen @irenetrampoline.bsky.social · 12/11/2024
Creative AIES 2024 paper by andreawwenyi.bsky.social that uses NLP to help uncover gender bias for men/women defendants. Legal experts used NLP to build consensus and evidence on annotation rules. Could have relevant tie-ins to healthcare and bias in clinical notes
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Alyssa Pradhan @alyssapradhan.bsky.social · 12/11/2024
Time for some shameless self promotion! If you're interested in learning more about the impacts, implementation and ethics of AI in healthcare, listen to my podcast 🤖
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Alyssa Pradhan @alyssapradhan.bsky.social · 11/11/2024
Celebrating joining bksy by reposting my favourite paper reviewing tip. I can’t recall the OP but this is how I use RSS feeds to game-ify looking at abstracts, hope it’s handy 🧵 #medsky #medtwitter #idtwitter #foamed #academictwitter #IDsky #academicsky
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Ilan Schwartz @germhuntermd.bsky.social · 10/11/2024
IDSky continues to grow rapidly We are now >300 users, which means we are on a third Starter Pack IDSky Starter Pack 1 go.bsky.app/LnAQjdq IDSky Starter Pack 2 go.bsky.app/JNfSvQT ID Starter Pack 3 go.bsky.app/FeogT7o Check back on the most recent one often as it is updated frequently
#IDSky Starter Pack heading with 7 photos of users IDSky Starter Pack 2 heading IDSky Starter Pack 3 header
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Roxana Daneshjou, MD, PhD @roxanadaneshjou.bsky.social · 08/11/2024
I’ve started an AI in healthcare starter pack! Let me know who is missing. go.bsky.app/7PeNwep
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Scott McGrath @smcgrath.phd · 25/10/2024
I created a starter pack for Health AI and Informatics. Mix of folks (reporters and researchers) that I think you should follow. I've got room to include more, so please tag anyone you think I should add! 🧪🩺 🤖 🛟
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Alyssa Pradhan @alyssapradhan.bsky.social · 09/11/2024
First day at #AMIA24, some great insights about evaluation of #LLM in healthcare. Also an apt time to scream into the #Medsky void, if you’re part of the #IDtwitter #Medtwitter #healthcareAI exodus, hmu
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